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1.

Research   Open Access

Chromoendoscopy in magnetically guided capsule endoscopy

Philip W Mewes, Stefan Foertsch, Aleksandar Lj Juloski, Elli Angelopoulou, Stefan K Goelder, Dirk Guldi, Joachim Hornegger, Helmut Messmann BioMedical Engineering OnLine 2013, 12:52 (11 June 2013)

Abstract | Provisional PDF | PubMed

2.

Research article   Open Access

Two recently duplicated maize NAC transcription factor paralogs are induced in response to Colletotrichum graminicola infection

Anna-Maria Voitsik, Steffen Muench, Holger B Deising, Lars M Voll BMC Plant Biology 2013, 13:85 (29 May 2013)

Abstract | Provisional PDF | PubMed

3.

Research article   Open Access

Catabolic and anabolic periarticular bone changes in patients with rheumatoid arthritis: a computed tomography study on the role of age, disease duration and bone markers

Sophie Aschenberg, Stephanie Finzel, Sarah Schmidt, Sebastian Kraus, Klaus Engelke, Matthias Englbrecht, Juergen Rech, Georg Schett Arthritis Research & Therapy 2013, 15:R62 (27 May 2013)

Abstract | Provisional PDF | PubMed

4.

Research   Open Access Highly Accessed

Limited cross-border infections in patients newly diagnosed with HIV in Europe

Dineke Frentz, Annemarie M J Wensing, Jan Albert, Dimitrios Paraskevis, Ana B Abecasis, Osamah Hamouda, Louise B Jørgensen, Claudia Kücherer, Daniel Struck, Jean-Claude Schmit, Birgitta Åsjö, Claudia Balotta, Danail Beshkov, Ricardo J Camacho, Bonaventura Clotet, Suzie Coughlan, Stéphane De Wit, Algirdas Griskevicius, Zehava Grossman, Andrzej Horban, Tatjana Kolupajeva, Klaus Korn, Leondios G Kostrikis, Kirsi Liitsola, Marek Linka, Claus Nielsen, Dan Otelea, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Anders Sönnerborg, Danica Stanekova, Maja Stanojevic, Anne-Mieke Vandamme, Charles A B Boucher, David A M C Van de Vijver, et al. Retrovirology 2013, 10:36 (3 April 2013)

Abstract | Full text | PDF | PubMed

5.

Poster presentation   Open Access

Is the novel amyloid-β tetramer fold a stable conformation?

Eileen Socher, Anselm HC Horn, Heinrich Sticht Journal of Cheminformatics 2013, 5(Suppl 1):P10 (22 March 2013)

Full text | PDF

6.

Poster presentation   Open Access

Stability of single and double layer fibrillar amyloid-β oligomers

Anna Kahler, Anselm HC Horn, Heinrich Sticht Journal of Cheminformatics 2013, 5(Suppl 1):P9 (22 March 2013)

Full text | PDF

7.

Research article   Open Access Highly Accessed

Evaluation of data completeness in the electronic health record for the purpose of patient recruitment into clinical trials: a retrospective analysis of element presence

Felix Köpcke, Benjamin Trinczek, Raphael W Majeed, Björn Schreiweis, Joachim Wenk, Thomas Leusch, Thomas Ganslandt, Christian Ohmann, Björn Bergh, Rainer Röhrig, Martin Dugas, Hans-Ulrich Prokosch BMC Medical Informatics and Decision Making 2013, 13:37 (21 March 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Early versus deferred androgen suppression therapy for patients with lymph node-positive prostate cancer after local therapy with curative intent: a systematic review

Frank Kunath, Bastian Keck, Gerta Rücker, Edith Motschall, Bernd Wullich, Gerd Antes, Joerg J Meerpohl BMC Cancer 2013, 13:131 (19 March 2013)

Abstract | Full text | PDF | PubMed

9.

Study protocol   Open Access

Effects of behavioural exercise therapy on the effectiveness of a multidisciplinary rehabilitation for chronic non-specific low back pain: Study protocol for a randomised controlled trial

Jana Hofmann, Stefan Peters, Wolfgang Geidl, Christian Hentschke, Klaus Pfeifer BMC Musculoskeletal Disorders 2013, 14:89 (11 March 2013)

Abstract | Full text | PDF | PubMed

10.

Review   Open Access Highly Accessed

Physical inactivity as a policy problem: applying a concept from policy analysis to a public health issue

Alfred Rütten, Karim Abu-Omar, Peter Gelius, Diana Schow Health Research Policy and Systems 2013, 11:9 (7 March 2013)

Abstract | Full text | PDF | PubMed

11.

Research   Open Access Highly Accessed

Restriction of diverse retroviruses by SAMHD1

Thomas Gramberg, Tanja Kahle, Nicolin Bloch, Sabine Wittmann, Erik Müllers, Waaqo Daddacha, Henning Hofmann, Baek Kim, Dirk Lindemann, Nathaniel R Landau Retrovirology 2013, 10:26 (5 March 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

Oncofertility: combination of ovarian stimulation with subsequent ovarian tissue extraction on the day of oocyte retrieval

Ralf Dittrich, Laura Lotz, Andreas Mueller, Inge Hoffmann, David L Wachter, Kerstin U Amann, Matthias W Beckmann, Thomas Hildebrandt Reproductive Biology and Endocrinology 2013, 11:19 (5 March 2013)

Abstract | Full text | PDF | PubMed

13.

Research article   Open Access

Plasmacytoid variant of bladder cancer defines patients with poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy

Bastian Keck, Sven Wach, Robert Stoehr, Frank Kunath, Simone Bertz, Jan Lehmann, Michael Stöckle, Helge Taubert, Bernd Wullich, Arndt Hartmann BMC Cancer 2013, 13:71 (8 February 2013)

Abstract | Full text | PDF | PubMed

14.

Review   Open Access Highly Accessed

The skin prick test – European standards

Lucie Heinzerling, Adriano Mari, Karl-Christian Bergmann, Megon Bresciani, Guido Burbach, Ulf Darsow, Stephen Durham, Wytske Fokkens, Mark Gjomarkaj, Tari Haahtela, Ana Todo Bom, Stefan Wöhrl, Howard Maibach, Richard Lockey Clinical and Translational Allergy 2013, 3:3 (1 February 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

Nano Express   Open Access

Kinetic study of H-terminated silicon nanowires oxidation in very first stages

Muhammad Y Bashouti, Kasra Sardashti, Jürgen Ristein, Silke Christiansen Nanoscale Research Letters 2013, 8:41 (21 January 2013)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access Highly Accessed

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

Ana B Abecasis, Annemarie MJ Wensing, Dimitris Paraskevis, Jurgen Vercauteren, Kristof Theys, David AMC Van de Vijver, Jan Albert, Birgitta Asjö, Claudia Balotta, Danail Beshkov, Ricardo J Camacho, Bonaventura Clotet, Cillian De Gascun, Algis Griskevicius, Zehava Grossman, Osamah Hamouda, Andrzej Horban, Tatjana Kolupajeva, Klaus Korn, Leon G Kostrikis, Claudia Kücherer, Kirsi Liitsola, Marek Linka, Claus Nielsen, Dan Otelea, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Jean-Claude Schmit, Anders Sönnerborg, Danika Stanekova, Maja Stanojevic, Daniel Struck, Charles AB Boucher, Anne-Mieke Vandamme et al. Retrovirology 2013, 10:7 (14 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The association of subtype with demographic parameters suggests highly compartmentalized epidemics, determined by social and behavioural characteristics of the patients.

17.

Research article   Open Access Highly Accessed

Impaction grafting in the femur in cementless modular revision total hip arthroplasty: a descriptive outcome analysis of 243 cases with the MRP-TITAN revision implant

Matthias D Wimmer, Thomas M Randau, Moritz C Deml, Rudolf Ascherl, Ulrich Nöth, Raimund Forst, Nadine Gravius, Dieter Wirtz, Sascha Gravius BMC Musculoskeletal Disorders 2013, 14:19 (11 January 2013)

Abstract | Full text | PDF | PubMed

18.

Database   Open Access Highly Accessed

OPTIMAS-DW: A comprehensive transcriptomics, metabolomics, ionomics, proteomics and phenomics data resource for maize

Christian Colmsee, Martin Mascher, Tobias Czauderna, Anja Hartmann, Urte Schlüter, Nina Zellerhoff, Jessica Schmitz, Andrea Bräutigam, Thea R Pick, Philipp Alter, Manfred Gahrtz, Sandra Witt, Alisdair R Fernie, Frederik Börnke, Holger Fahnenstich, Marcel Bucher, Thomas Dresselhaus, Andreas PM Weber, Falk Schreiber, Uwe Scholz, Uwe Sonnewald BMC Plant Biology 2012, 12:245 (29 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The OPTIMAS Data Warehouse (OPTIMAS-DW) is a comprehensive collection of data for maize, integrating data from different domains such as transcriptomics, metabolomics, ionomics, proteomics and phenomics, and particularly supports systems biological research

19.

Original article   Open Access

Why is there a gender earnings gap in self-employment? A decomposition analysis with German data

Daniel SJ Lechmann, Claus Schnabel IZA Journal of European Labor Studies 2012, 1:6 (28 December 2012)

Abstract | Full text | PDF

20.

Case report   Open Access

Membranoproliferative glomerulonephritis complicating Waldenström’s macroglobulinemia

David Kratochvil, Kerstin Amann, Heike Bruck, Maike Büttner BMC Nephrology 2012, 13:172 (21 December 2012)

Abstract | Full text | PDF | PubMed

21.

Methodology   Open Access

The perfused swine uterus model: long-term perfusion

Klaudija Geisler, Julian Künzel, Philipp Grundtner, Andreas Müller, Matthias W Beckmann, Ralf Dittrich Reproductive Biology and Endocrinology 2012, 10:110 (15 December 2012)

Abstract | Full text | PDF | PubMed

22.

Research article   Open Access

Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct

Oliver Bleiziffer, Matthias Hammon, Andreas Arkudas, Christian D Taeger, Justus P Beier, Kerstin Amann, Elisabeth Naschberger, Michael Stürzl, Raymund E Horch, Ulrich Kneser BMC Biotechnology 2012, 12:94 (6 December 2012)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Are the effects of a non-drug multimodal activation therapy of dementia sustainable? Follow-up study 10 months after completion of a randomised controlled trial

Katharina Luttenberger, Benjamin Hofner, Elmar Graessel BMC Neurology 2012, 12:151 (5 December 2012)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

Activities of daily living in dementia: revalidation of the E-ADL test and suggestions for further development

Katharina Luttenberger, Anke Schmiedeberg, Elmar Gräßel BMC Psychiatry 2012, 12:208 (23 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Methodology   Open Access

INTERBED: internet-based guided self-help for overweight and obese patients with full or subsyndromal binge eating disorder. A multicenter randomized controlled trial

Martina de Zwaan, Stephan Herpertz, Stephan Zipfel, Brunna Tuschen-Caffier, Hans-Christoph Friederich, Frauke Schmidt, Olaf Gefeller, Andreas Mayr, Tony Lam, Carmen Schade-Brittinger, Anja Hilbert Trials 2012, 13:220 (21 November 2012)

Abstract | Full text | PDF | PubMed

26.

Research article   Open Access Highly Accessed

Residual effects of muscle strength and muscle power training and detraining on physical function in community-dwelling prefrail older adults: a randomized controlled trial

Astrid Zech, Michael Drey, Ellen Freiberger, Christian Hentschke, Juergen M Bauer, Cornel C Sieber, Klaus Pfeifer BMC Geriatrics 2012, 12:68 (7 November 2012)

Abstract | Full text | PDF | PubMed

27.

Research   Open Access Highly Accessed

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

Kristof Theys, Koen Deforche, Jurgen Vercauteren, Pieter Libin, David AMC van de Vijver, Jan Albert, Birgitta Åsjö, Claudia Balotta, Marie Bruckova, Ricardo J Camacho, Bonaventura Clotet, Suzie Coughlan, Zehava Grossman, Osamah Hamouda, Andrzei Horban, Klaus Korn, Leondios G Kostrikis, Claudia Kücherer, Claus Nielsen, Dimitrios Paraskevis, Mario Poljak, Elisabeth Puchhammer-Stockl, Chiara Riva, Lidia Ruiz, Kirsi Liitsola, Jean-Claude Schmit, Rob Schuurman, Anders Sönnerborg, Danica Stanekova, Maja Stanojevic, Daniel Struck, Kristel Van Laethem, Annemarie MJ Wensing, Charles AB Boucher, Anne-Mieke Vandamme, et al. Retrovirology 2012, 9:81 (3 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The evolutionary cost of drug resistance (TDR) in HIV should result in a 'less fit' virus in the absence of drugs, but in newly infected people, TDR strains have gained unexpected virulence with worrying implications on future therapy.

28.

Research article   Open Access

Acceptance of virtual dental implant planning software in an undergraduate curriculum: a pilot study

Emeka Nkenke, Elefterios Vairaktaris, Anne Bauersachs, Stephan Eitner, Alexander Budach, Christian Knipfer, Florian Stelzle BMC Medical Education 2012, 12:90 (29 September 2012)

Abstract | Full text | PDF | PubMed

29.

Research   Open Access Highly Accessed

Cost-effectiveness of vaccination with a quadrivalent HPV vaccine in Germany using a dynamic transmission model

Deniz Schobert, Vanessa Remy, Oliver Schoeffski Health Economics Review 2012, 2:19 (25 September 2012)

Abstract | Full text | PDF | PubMed

30.

Case report   Open Access

Chronic calcium pyrophosphate crystal inflammatory arthritis induced by extreme hypomagnesemia in short bowel syndrome

Markus Hahn, Martin Raithel, Alexander Hagel, Teresa Biermann, Bernhard Manger BMC Gastroenterology 2012, 12:129 (22 September 2012)

Abstract | Full text | PDF | PubMed

31.

Research   Open Access Highly Accessed

Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons

Alexandra B Klinger, Mirjam Eberhardt, Andrea S Link, Barbara Namer, Lisa K Kutsche, E Schuy, Ruth Sittl, Tali Hoffmann, Christian Alzheimer, Tobias Huth, Richard W Carr, Angelika Lampert Molecular Pain 2012, 8:69 (15 September 2012)

Abstract | Full text | PDF | PubMed

32.

Research   Open Access

Corticotropin-releasing hormone stimulates expression of leptin, 11beta-HSD2 and syncytin-1 in primary human trophoblasts

Fabian B Fahlbusch, Matthias Ruebner, Gudrun Volkert, Ramona Offergeld, Andrea Hartner, Carlos Menendez-Castro, Reiner Strick, Manfred Rauh, Wolfgang Rascher, Jörg Dötsch Reproductive Biology and Endocrinology 2012, 10:80 (12 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

Research article   Open Access

Basic geriatric assessment does not predict in-hospital mortality after PEG placement

Christine Smoliner, Dorothee Volkert, Anke Wittrich, Cornel C Sieber, Rainer Wirth BMC Geriatrics 2012, 12:52 (6 September 2012)

Abstract | Full text | PDF | PubMed

34.

Research article   Open Access Highly Accessed

Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines

Steffen Zopf, Matthias Ocker, Daniel Neureiter, Beate Alinger, Susanne Gahr, Markus F Neurath, Pietro Di Fazio BMC Cancer 2012, 12:386 (3 September 2012)

Abstract | Full text | PDF | PubMed

35.

Research   Open Access

Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells

Jonathan Zuehlke, Astrid Ebenau, Bettina Krueger, Margarete Goppelt-Struebe Cell Communication and Signaling 2012, 10:25 (2 September 2012)

Abstract | Full text | PDF | PubMed

36.

Research   Open Access

Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH)

Patricia G Oppelt, Johannes Lermann, Reiner Strick, Ralf Dittrich, Pamela Strissel, Ingo Rettig, Christine Schulze, Stefan P Renner, Matthias W Beckmann, Sara Brucker, Katharina Rall, Andreas Mueller Reproductive Biology and Endocrinology 2012, 10:57 (20 August 2012)

Abstract | Full text | PDF | PubMed

37.

Research article   Open Access

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

Bogumiła C Marciniak, Monika Pabijaniak, Anne de Jong, Robert Dűhring, Gerald Seidel, Wolfgang Hillen, Oscar P Kuipers BMC Genomics 2012, 13:401 (17 August 2012)

Abstract | Full text | PDF | PubMed

38.

Case report   Open Access

Unexpected recovery from longterm renal failure in severe diffuse proliferative lupus nephritis

Sophia Ross, Kerstin Benz, Katja Sauerstein, Kerstin Amann, Jörg Dötsch, Katalin Dittrich BMC Nephrology 2012, 13:81 (6 August 2012)

Abstract | Full text | PDF | PubMed

39.

Research   Open Access

Opposing effects of Notch-signaling in maintaining the proliferative state of follicle cells in the telotrophic ovary of the beetle Tribolium

Daniel Bäumer, Nadi M Ströhlein, Michael Schoppmeier Frontiers in Zoology 2012, 9:15 (6 August 2012)

Abstract | Full text | PDF | PubMed

40.

Research article   Open Access

Expression of human Piwi-like genes is associated with prognosis for soft tissue sarcoma patients

Thomas Greither, Franziska Koser, Matthias Kappler, Matthias Bache, Christine Lautenschläger, Steffen Göbel, Hans-Jürgen Holzhausen, Sven Wach, Peter Würl, Helge Taubert BMC Cancer 2012, 12:272 (29 June 2012)

Abstract | Full text | PDF | PubMed

41.

Research article   Open Access

Risk of tobacco-related multiple primary cancers in Bavaria, Germany

Ulrike Braisch, Martin Meyer, Martin Radespiel-Tröger BMC Cancer 2012, 12:250 (18 June 2012)

Abstract | Full text | PDF | PubMed

42.

Research   Open Access

The impact of laser ablation on optical soft tissue differentiation for tissue specific laser surgery-an experimental ex vivo study

Florian Stelzle, Ingo Terwey, Christian Knipfer, Werner Adler, Katja Tangermann-Gerk, Emeka Nkenke, Michael Schmidt Journal of Translational Medicine 2012, 10:123 (15 June 2012)

Abstract | Full text | PDF | PubMed

43.

Research article   Open Access Highly Accessed

Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia

Evgeny A Moskalev, Katrin Luckert, Ivan A Vorobjev, Sergey E Mastitsky, Aleena A Gladkikh, Achim Stephan, Marita Schrenk, Kamil D Kaplanov, Olga B Kalashnikova, Oliver Pötz, Thomas O Joos, Jörg D Hoheisel BMC Cancer 2012, 12:213 (6 June 2012)

Abstract | Full text | PDF | PubMed

44.

Research article   Open Access Highly Accessed

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

Kelly M Hinkle, Mei Yue, Bahareh Behrouz, Justus C Dächsel, Sarah J Lincoln, Erin E Bowles, Joel E Beevers, Brittany Dugger, Beate Winner, Iryna Prots, Caroline B Kent, Kenya Nishioka, Wen-Lang Lin, Dennis W Dickson, Christopher J Janus, Matthew J Farrer, Heather L Melrose Molecular Neurodegeneration 2012, 7:25 (30 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

LRRK2 knockout mice have a normal dopaminergic system and do not develop any pathological features of Parkinsons disease, but they do display altered exploratory and motor co-ordination behaviors, and degeneration in the kidney.

45.

Research article   Open Access Highly Accessed

The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines

Khuloud Bajbouj, Jan Schulze-Luehrmann, Stefanie Diermeier, Amr Amin, Regine Schneider-Stock BMC Complementary and Alternative Medicine 2012, 12:69 (28 May 2012)

Abstract | Full text | PDF | PubMed

46.

Research article   Open Access

Spaced education activates students in a theoretical radiological science course: a pilot study

Emeka Nkenke, Elefterios Vairaktaris, Anne Bauersachs, Stephan Eitner, Alexander Budach, Christian Knipfer, Florian Stelzle BMC Medical Education 2012, 12:32 (23 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

Case report   Open Access

A complex microdeletion 17q12 phenotype in a patient with recurrent de novo membranous nephropathy

Bernward Hinkes, Karl F Hilgers, Hanno J Bolz, Margarete Goppelt-Struebe, Kerstin Amann, Sandra Nagl, Carsten Bergmann, Wolfgang Rascher, Kai-Uwe Eckardt, Johannes Jacobi BMC Nephrology 2012, 13:27 (14 May 2012)

Abstract | Full text | PDF | PubMed

48.

Original basic research   Open Access

Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway

Hans-Georg Topf, Manfred Rauh, Wolfgang Rascher, Jörg Dötsch, Jens M Klinge Thrombosis Journal 2012, 10:6 (7 May 2012)

Abstract | Full text | PDF | PubMed

49.

Research article   Open Access

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization

Beate Böhm, Harald Burkhardt, Steffen Uebe, Maria Apel, Frank Behrens, André Reis, Ulrike Hüffmeier Arthritis Research & Therapy 2012, 14:R84 (18 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

Research   Open Access

Policy assessment and policy development for physical activity promotion: results of an exploratory intervention study in 15 European Nations

Alfred Rütten, Karim Abu-Omar, Peter Gelius, Susie Dinan-Young, Kerstin Frändin, Marijke Hopman-Rock, Archie Young Health Research Policy and Systems 2012, 10:14 (18 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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