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1.

Study protocol   Open Access

The combined effect of chemoprophylaxis with single dose rifampicin and immunoprophylaxis with BCG to prevent leprosy in contacts of newly diagnosed leprosy cases: a cluster randomized controlled trial (MALTALEP study)

Renate A Richardus, Khorshed Alam, David Pahan, Sabiena G Feenstra, Annemieke Geluk, Jan H Richardus BMC Infectious Diseases 2013, 13:456 (3 October 2013)

Abstract | Provisional PDF

2.

Case report   Open Access

Post-transplantation encapsulating peritoneal sclerosis without inflammation or radiological abnormalities

Sayed Habib, Frank Johan Marinus Frederik Dor, Mario Korte, Sander Hagen, Michiel Gerardus Betjes BMC Nephrology 2013, 14:203 (26 September 2013)

Abstract | Full text | PDF | PubMed

3.

Research article   Open Access

Mixed venous O2 saturation and fluid responsiveness after cardiac or major vascular surgery

Arjan N Kuiper, Ronald J Trof, AB Groeneveld Journal of Cardiothoracic Surgery 2013, 8:189 (22 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis

Fabiola Puentes, Baukje J van der Star, Marion Victor, Markus Kipp, Cordian Beyer, Regina Peferoen-Baert, Kimberley Ummenthum, Gareth Pryce, Wouter Gerritsen, Ruth Huizinga, Arie Reijerkerk, Paul van der Valk, David Baker, Sandra Amor Journal of Neuroinflammation 2013, 10:118 (22 September 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

Jeroen CH Leijten, Steffan D Bos, Ellie BM Landman, Nicole Georgi, Holger Jahr, Ingrid Meulenbelt, Janine N Post, Clemens A van Blitterswijk, Marcel Karperien Arthritis Research & Therapy 2013, 15:R126 (19 September 2013)

Abstract | Full text | PDF

6.

Research   Open Access

Aggravation of myocardial dysfunction by injurious mechanical ventilation in LPS-induced pneumonia in rats

Lonneke Smeding, Jan Kuiper, Frans B Plötz, Martin CJ Kneyber, AB Groeneveld Respiratory Research 2013, 14:92 (18 September 2013)

Abstract | Full text | PDF | PubMed

7.

Research   Open Access

ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase

Johannes Hofland, Leo J Hofland, Peter M van Koetsveld, Jacobie Steenbergen, Wouter W de Herder, Casper H van Eijck, Ronald R de Krijger, Francien H van Nederveen, Maarten O van Aken, Johannes W de Groot, Thera P Links, Frank H de Jong, Richard A Feelders Orphanet Journal of Rare Diseases 2013, 8:142 (13 September 2013)

Abstract | Full text | PDF | PubMed

8.

Research   Open Access

Accurate IMRT fluence verification for prostate cancer patients using 'in-vivo' measured EPID images and in-room acquired kilovoltage cone-beam CT scans

Ali ASAM Ali, Maarten MLP Dirkx, Ruud RM Cools, Ben BJM Heijmen Radiation Oncology 2013, 8:211 (10 September 2013)

Abstract | Provisional PDF | PubMed

9.

Oral presentation   Open Access

cGMP-dependent kinase 2, Na+/H+ regulatory factor 2, and Na+/H+ exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane

Min Luo, Ayesha Sultan, Qin Yu, Brigitte Riederer, Weiliang Xia, Min Luo, Mingmin Chen, Simone Lissner, Engelbert Gessner, Enrico Patrucco, Franz Hofmann, Mark Donowitz, Chris C Yun, Hugo de Jonge, Georg Lamprecht, Ursula Seidler BMC Pharmacology and Toxicology 2013, 14(Suppl 1):O31 (29 August 2013)

Full text | PDF

10.

Speaker presentation   Open Access

Development of a standardised instrument to assess ageing-related health outcomes in a comparable fashion in European ageing populations, the CHANCES Health Module

Martin Bobak, Simone Croezen BMC Proceedings 2013, 7(Suppl 4):S7 (23 August 2013)

Full text | PDF

11.

Speaker presentation   Open Access

Comparing health outcomes in SHARE with other European surveys

Simone Croezen, Mauricio Avendano, Alex Burdorf, Frank J van Lenthe BMC Proceedings 2013, 7(Suppl 4):S2 (23 August 2013)

Full text | PDF

12.

Methodology article   Open Access

Computational estimation of tricarboxylic acid cycle fluxes using noisy NMR data from cardiac biopsies

Hannes Hettling, David J C Alders, Jaap Heringa, Thomas W Binsl, A B Groeneveld, Johannes H G M van Beek BMC Systems Biology 2013, 7:82 (21 August 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access Highly Accessed

Incremental value of rare genetic variants for the prediction of multifactorial diseases

Raluca Mihaescu, Michael J Pencina, Alvaro Alonso, Kathryn L Lunetta, Susan R Heckbert, Emelia J Benjamin, A JW Janssens Genome Medicine 2013, 5:76 (20 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Rare variants are only useful for predicting the risk of complex diseases when they have strong effects on disease risk, when they are not too rare and when the risk of disease is high.

14.

Research article   Open Access

Transcriptional profiling reveals progeroid Ercc1 -/Δ mice as a model system for glomerular aging

Bernhard Schermer, Valerie Bartels, Peter Frommolt, Bianca Habermann, Fabian Braun, Joachim L Schultze, Marianne Roodbergen, Jan HJ Hoeijmakers, Björn Schumacher, Peter Nürnberg, Martijn ET Dollé, Thomas Benzing, Roman-Ulrich Müller, Christine E Kurschat BMC Genomics 2013, 14:559 (16 August 2013)

Abstract | Full text | PDF | PubMed

15.

Commentary   Subscription Highly Accessed

Transition of mesenchymal stem/stromal cells to endothelial cells

Mihaela Crisan Stem Cell Research & Therapy 2013, 4:95 (14 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Mihaela Crisan comments on recent research on the effect of isolation protocols and culture conditions on the endothelial differentiation of human Wharton’s jelly-derived cells, demonstrating the need for well-controlled procedures.

16.

Study protocol   Open Access

Development and evaluation of a structured programme for promoting physical activity among seniors with intellectual disabilities: a study protocol for a cluster randomized trial

Marieke van Schijndel-Speet, Heleen M Evenhuis, Pepijn van Empelen, Ruud van Wijck, Michael A Echteld BMC Public Health 2013, 13:746 (12 August 2013)

Abstract | Full text | PDF | PubMed

17.

Study protocol   Open Access

The effectiveness of aerobic training, cognitive behavioural therapy, and energy conservation management in treating MS-related fatigue: the design of the TREFAMS-ACE programme

Heleen Beckerman, Lyan JM Blikman, Martin Heine, Arjan Malekzadeh, Charlotte E Teunissen, Johannes BJ Bussmann, Gert Kwakkel, Jetty van Meeteren, Vincent de Groot, Trials 2013, 14:250 (12 August 2013)

Abstract | Full text | PDF | PubMed

18.

Research article   Open Access Highly Accessed

Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis: a hypothesis generating post hoc analysis

Namkje AR Vellinga, Can Ince, E Boerma BMC Anesthesiology 2013, 13:17 (7 August 2013)

Abstract | Full text | PDF | PubMed

19.

Review   Open Access

Dose and type of crystalloid fluid therapy in adult hospitalized patients

Annemieke Smorenberg, Can Ince, AB Groeneveld Perioperative Medicine 2013, 2:17 (6 August 2013)

Abstract | Full text | PDF

20.

Research article   Open Access Highly Accessed

Low agreement between cardiologists diagnosing left ventricular hypertrophy in children with end-stage renal disease

Nikki J Schoenmaker, Johanna H van der Lee, Jaap W Groothoff, Gabrielle G van Iperen, Ingrid ME Frohn-Mulder, Ronald B Tanke, Jaap Ottenkamp, Irene M Kuipers BMC Nephrology 2013, 14:170 (2 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Changes in diastolic wall thickness of less than 1.6 mm or left ventricle mass index of less than 17.7 g/m2 cannot be distinguished from measurement error when monitoring the appearance of left ventricular hypertrophy (LVH) by echocardiography in children with ESRD.

21.

Research   Open Access

Severity of imported malaria: protective effect of taking malaria chemoprophylaxis

Klaske Vliegenthart-Jongbloed, Mariana de Mendonça Melo, Marlies E van Wolfswinkel, Rob Koelewijn, Jaap J van Hellemond, Perry JJ van Genderen Malaria Journal 2013, 12:265 (31 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An observational study quantifying the protective effect of malaria chemoprophylaxis in a large cohort of Dutch travellers. The results provide useful information for travel clinics.

22.

Review   Open Access Highly Accessed

Evolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: from treatment to prevention

Ravindra K Gupta, David A M C Van de Vijver, Sheetal Manicklal, Mark A Wainberg Retrovirology 2013, 10:82 (31 July 2013)

Abstract | Full text | PDF | PubMed

23.

Editorial   Open Access Highly Accessed

Editors’ Pick: mad and genius in the same gene?

Manfred Kayser Investigative Genetics 2013, 4:14 (26 July 2013)

Full text | PDF | PubMed |  Editor’s summary

It is often said that 'there is a fine line between genius and madness.' Professor Manfred Kayser discusses the available evidence for this link.

24.

Study protocol   Open Access

The NLstart2run study: health effects of a running promotion program in novice runners, design of a prospective cohort study

Bas Kluitenberg, Marienke van Middelkoop, Ron L Diercks, Fred Hartgens, Evert Verhagen, Dirk-Wouter Smits, Ida Buist, Henk van der Worp BMC Public Health 2013, 13:685 (26 July 2013)

Abstract | Full text | PDF | PubMed

25.

Research article   Open Access

Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0

Alexander Teumer, Florian D Ernst, Anja Wiechert, Katharina Uhr, Matthias Nauck, Astrid Petersmann, Henry Völzke, Uwe Völker, Georg Homuth BMC Genomics 2013, 14:506 (26 July 2013)

Abstract | Full text | PDF | PubMed

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