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1.

Research article   Open Access

Improving sensitivity of machine learning methods for automated case identification from free-text electronic medical records

Zubair Afzal, Martijn J Schuemie, Jan C van Blijderveen, Elif F Sen, Miriam CJM Sturkenboom, Jan A Kors BMC Medical Informatics and Decision Making 2013, 13:30 (2 March 2013)

Abstract | Provisional PDF

2.

Editorial   Open Access

Epigenetics & chromatin: interactions and processes

Steven Henikoff, Frank Grosveld Epigenetics & Chromatin 2013, 6:2 (27 February 2013)

Abstract | Full text | PDF | PubMed

3.

Poster presentation   Open Access

Capsaicin-induced CGRP-mediated vasodilatation of the human skin: influence of gender, female hormones and migraine

SGG Vermeersch, P Frederiks, A Maassen VandenBrink, J de Hoon The Journal of Headache and Pain 2013, $article.volume.volumeNumber(Suppl 1):P124 (21 February 2013)

Full text | PDF

4.

Poster presentation   Open Access

Influence of varying estrogen levels on trigeminal CGRP release in healthy women

K Ibrahimi, AHJ Danser, CM Villalón, AH van den Meiracker, A MaassenVanDenBrink The Journal of Headache and Pain 2013, $article.volume.volumeNumber(Suppl 1):P123 (21 February 2013)

Full text | PDF

5.

Protocol   Open Access

Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT)

Georg M Schuetz, Peter Schlattmann, Stephan Achenbach, Matthew Budoff, Mario J Garcia, Robert Roehle, Gianluca Pontone, Willem Bob Meijboom, Daniele Andreini, Hatem Alkadhi, Lily Honoris, Nuno Bettencourt, Jörg Hausleiter, Sebastian Leschka, Bernhard L Gerber, Matthijs FL Meijs, Abbas Arjmand Shabestari, Akira Sato, Elke Zimmermann, Uwe J Schoepf, Axel Diederichsen, David A Halon, Vladimir Mendoza-Rodriguez, Ashraf Hamdan, Bjarne L Nørgaard, Harald Brodoefel, Kristian A Øvrehus, Shona MM Jenkins, Bjørn A Halvorsen, Johannes Rixe et al. Systematic Reviews 2013, 2:13 (15 February 2013)

Abstract | Full text | PDF | PubMed

6.

Research   Open Access Highly Accessed

The joint action on healthy life years (JA: EHLEIS)

Jean-Marie Robine, Emmanuelle Cambois, Wilma Nusselder, Bernard Jeune, Herman Van Oyen, Carol Jagger Archives of Public Health 2013, 71:2 (4 February 2013)

Abstract | Provisional PDF | PubMed

7.

Study protocol   Open Access

Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

M Jenda Hop, Jakob Hiddingh, Carlijn Stekelenburg, Hester C Kuipers, Esther Middelkoop, Marianne K Nieuwenhuis, Suzanne Polinder, Margriet E van Baar, BMC Surgery 2013, 13:2 (1 February 2013)

Abstract | Full text | PDF | PubMed

8.

Oral presentation   Open Access

Quantification of left ventricular regional myocardial function using MRI feature tracking in healthy children - a dual-center study

Joachim G Eichhorn, Sebastian Buss, Angela Foell, Astrid Helling, Daniel Robbers-Visser, E Pieterman, Sjoerd Bossers, Dirk Lossnitzer, Matthias Gorenflo, Willem A Helbing Journal of Cardiovascular Magnetic Resonance 2013, 15(Suppl 1):O42 (30 January 2013)

Full text | PDF

9.

Poster presentation   Open Access

Robust motion correction in the frequency domain of cardiac MR stress perfusion sequences

Vikas Gupta, Martijn Van de Giessen, Hortense Kirisli, Sharon Kirschbaum, Rob J van der Geest, Wiro J Niessen, Boudewijn Lelieveldt Journal of Cardiovascular Magnetic Resonance 2013, 15(Suppl 1):P41 (30 January 2013)

Full text | PDF

10.

Research article   Open Access

Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data

Kristina M Hettne, André Boorsma, Dorien A M van Dartel, Jelle J Goeman, Esther de Jong, Aldert H Piersma, Rob H Stierum, Jos C Kleinjans, Jan A Kors BMC Medical Genomics 2013, 6:2 (29 January 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

The Prevention and Reactivation Care Program: intervention fidelity matters

Annemarie JBM de Vos, Ton JEM Bakker, Paul L de Vreede, Jeroen DH van Wijngaarden, Ewout W Steyerberg, Johan P Mackenbach, Anna P Nieboer BMC Health Services Research 2013, 13:29 (26 January 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

Why a successful task substitution in glaucoma care could not be transferred from a hospital setting to a primary care setting: a qualitative study

Kim M Holtzer-Goor, Thomas Plochg, Hans G Lemij, Esther van Sprundel, Marc A Koopmanschap, Niek S Klazinga Implementation Science 2013, 8:14 (25 January 2013)

Abstract | Full text | PDF | PubMed

13.

Study protocol   Open Access

Rotterdam Aphasia Therapy Study (RATS) – 3: “The efficacy of intensive cognitive-linguistic therapy in the acute stage of aphasia”; design of a randomised controlled trial

Femke Nouwens, Diederik WJ Dippel, Marjolein de Jong-Hagelstein, Evy G Visch-Brink, Peter J Koudstaal, Lonneke M L de Lau, Trials 2013, 14:24 (23 January 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access Highly Accessed

Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes

Natalia V Rivera, Robert Carreras-Torres, Roberta Roncarati, Chiara Viviani-Anselmi, Francesca De Micco, Alessandra Mezzelani, Werner Koch, Petra Hoppmann, Adnan Kastrati, Alexandre FR Stewart, Li Chen, Robert Roberts, Lennart C Karssen, Najaf Amin, Valentina Trimarco, Raffaele Izzo, Guido Iaccarino, Gerolama Condorelli, Annibale A Puca, Paolo Pagnotta, Flavio Airoldi, Bruno Trimarco, Cornelia M van Duijn, Gianluigi Condorelli, Carlo Briguori BMC Medical Genetics 2013, 14:11 (23 January 2013)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access Highly Accessed

Serological profiles in nursery piglets colonized with Staphylococcus aureus

Florence Crombé, Wannes Vanderhaeghen, Corné P de Vogel, Willem J Van Wamel, Kurt Barbé, Katleen Hermans, Freddy Haesebrouck, Patrick Butaye Veterinary Research 2013, 44:4 (22 January 2013)

Abstract | Full text | PDF | PubMed

16.

Research article   Open Access

How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?

Jan Y Verbakel, Ann Van den Bruel, Matthew Thompson, Richard Stevens, Bert Aertgeerts, Rianne Oostenbrink, Henriette A Moll, Marjolein Y Berger, Monica Lakhanpaul, David Mant, Frank Buntinx, BMC Medicine 2013, 11:10 (15 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Clinical prediction rules to recognize infections in children do not show perfect diagnostic accuracy in high and low prevalence ambulatory care settings, suggesting that additional laboratory tests should be used to increase certainty.

17.

Research   Open Access Highly Accessed

Progress towards malaria control targets in relation to national malaria programme funding

Eline L Korenromp, Mehran Hosseini, Robert D Newman, Richard E Cibulskis Malaria Journal 2013, 12:18 (14 January 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Description of malaria control efforts and the funding received by national government and external donors during the 2003-2009 interval for 90 malaria-endemic countries.

18.

Research   Open Access Highly Accessed

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

Ana B Abecasis, Annemarie MJ Wensing, Dimitris Paraskevis, Jurgen Vercauteren, Kristof Theys, David AMC Van de Vijver, Jan Albert, Birgitta Asjö, Claudia Balotta, Danail Beshkov, Ricardo J Camacho, Bonaventura Clotet, Cillian De Gascun, Algis Griskevicius, Zehava Grossman, Osamah Hamouda, Andrzej Horban, Tatjana Kolupajeva, Klaus Korn, Leon G Kostrikis, Claudia Kücherer, Kirsi Liitsola, Marek Linka, Claus Nielsen, Dan Otelea, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Jean-Claude Schmit, Anders Sönnerborg, Danika Stanekova, Maja Stanojevic, Daniel Struck, Charles AB Boucher, Anne-Mieke Vandamme et al. Retrovirology 2013, 10:7 (14 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The association of subtype with demographic parameters suggests highly compartmentalized epidemics, determined by social and behavioural characteristics of the patients.

19.

Research   Open Access Highly Accessed

Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains

Jolanta Draus-Barini, Susan Walsh, Ewelina Pośpiech, Tomasz Kupiec, Henryk Głąb, Wojciech Branicki, Manfred Kayser Investigative Genetics 2013, 4:3 (14 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Externally visible human features can be predicted from 800-year old bones. A novel technique is reported to predict hair and eye colour from just skeletal remains.

20.

Original research   Open Access

Treatment of penetrating trauma of the extremities: ten years’ experience at a dutch level 1 trauma center

Oscar JF Van Waes, Esther MM Van Lieshout, Wouter Hogendoorn, Jens A Halm, Jefrey Vermeulen Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2013, 21:2 (14 January 2013)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access

Chronic disease prevalence from Italian administrative databases in the VALORE project: a validation through comparison of population estimates with general practice databases and national survey

Rosa Gini, Paolo Francesconi, Giampiero Mazzaglia, Iacopo Cricelli, Alessandro Pasqua, Pietro Gallina, Salvatore Brugaletta, Daniele Donato, Andrea Donatini, Alessandro Marini, Carlo Zocchetti, Claudio Cricelli, Gianfranco Damiani, Mariadonata Bellentani, Miriam CJM Sturkenboom, Martijn J Schuemie BMC Public Health 2013, 13:15 (9 January 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Changes in Timing and kinematics of goal directed eye-hand movements in early-stage Parkinson’s disease

Danya Muilwijk, Simone Verheij, Johan JM Pel, Agnita JW Boon, Johannes van der Steen Translational Neurodegeneration 2013, 2:1 (9 January 2013)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access Highly Accessed

Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature

David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.

24.

Study protocol   Open Access Highly Accessed

Cost-effectiveness of minimal interventional procedures for chronic mechanical low back pain: design of four randomised controlled trials with an economic evaluation

Esther T Maas, Johan NS Juch, J George Groeneweg, Raymond WJG Ostelo, Bart W Koes, Arianne P Verhagen, Merel van Raamt, Frank Wille, Frank JPM Huygen, Maurits W van Tulder BMC Musculoskeletal Disorders 2012, 13:260 (28 December 2012)

Abstract | Full text | PDF | PubMed | 1 comment

25.

Research article   Open Access

Prevalence rate, predictors and long-term course of probable posttraumatic stress disorder after major trauma: a prospective cohort study

Juanita A Haagsma, Akkie N Ringburg, Esther MM van Lieshout, Ed F van Beeck, Peter Patka, Inger B Schipper, Suzanne Polinder BMC Psychiatry 2012, 12:236 (27 December 2012)

Abstract | Full text | PDF | PubMed

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