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1.

Research article   Open Access

Association of plasma endotoxin, inflammatory cytokines and risk of colorectal adenomas

Melissa Kang, Patrick Edmundson, Felix Araujo-Perez, Amber N McCoy, Joseph Galanko, Temitope O Keku BMC Cancer 2013, 13:91 (26 February 2013)

Abstract | Provisional PDF | PubMed

2.

Research Article   Open Access

On the exoneration of Dr. William H. Stewart: debunking an urban legend

Brad Spellberg, Bonnie Taylor-Blake Infectious Diseases of Poverty 2013, 2:3 (18 February 2013)

Abstract | Full text | PDF |  Editor’s summary

It is time to close the book on infectious diseases, and declare the war against pestilence won - One of the most infamous quotes in the history of biomedicine, long attributed to the United States Surgeon General, Dr. William H. Stewart (1965-1969), is now shown to be an urban legend with origins in legitimate public health policy. Image: It is from 1965, and shows William Stewart as Surgeon General on the far left, with President Johnson in the middle, and NIH Director Dr. James Shannon on the right.

3.

Research   Open Access

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease

Ted Wun, Denis Soulieres, Andrew L Frelinger, Lakshmanan Krishnamurti, Enrico M Novelli, Abdullah Kutlar, Kenneth I Ataga, Charles L Knupp, Lillian E McMahon, John J Strouse, Chunmei Zhou, Lori E Heath, Chuke E Nwachuku, Joseph A Jakubowski, Jeffrey S Riesmeyer, Kenneth J Winters Journal of Hematology & Oncology 2013, 6:17 (17 February 2013)

Abstract | Full text | PDF | PubMed

4.

Review   Open Access Highly Accessed

Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution

Lin Yang, Xiao Xiao Virology Journal 2013, 10:50 (11 February 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access Highly Accessed

Patient safety and quality improvement education: a cross-sectional study of medical students’ preferences and attitudes

Claire L Teigland, Rachel C Blasiak, Lindsay A Wilson, Rachel E Hines, Karen L Meyerhoff, Anthony J Viera BMC Medical Education 2013, 13:16 (5 February 2013)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access Highly Accessed

International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)

Jacob M Wilson, Peter J Fitschen, Bill Campbell, Gabriel J Wilson, Nelo Zanchi, Lem Taylor, Colin Wilborn, Douglas S Kalman, Jeffrey R Stout, Jay R Hoffman, Tim N Ziegenfuss, Hector L Lopez, Richard B Kreider, Abbie E Smith-Ryan, Jose Antonio Journal of the International Society of Sports Nutrition 2013, 10:6 (2 February 2013)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Lifestyle change in Kerala, India: needs assessment and planning for a community-based diabetes prevention trial

Meena Daivadanam, Pilvikki Absetz, Thirunavukkarasu Sathish, K R Thankappan, Edwin B Fisher, Neena Elezebeth Philip, Elezebeth Mathews, Brian Oldenburg BMC Public Health 2013, 13:95 (1 February 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Exploring the potential for using results-based financing to address non-communicable diseases in low- and middle-income countries

Chelsey R Beane, Suzanne Havala Hobbs, Harsha Thirumurthy BMC Public Health 2013, 13:92 (1 February 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access Highly Accessed

Public health program capacity for sustainability: a new framework

Sarah F Schell, Douglas A Luke, Michael W Schooley, Michael B Elliott, Stephanie H Herbers, Nancy B Mueller, Alicia C Bunger Implementation Science 2013, 8:15 (1 February 2013)

Abstract | Provisional PDF | PubMed

10.

Research   Open Access Highly Accessed

Characterizing biobank organizations in the U.S.: results from a national survey

Gail E Henderson, R Jean Cadigan, Teresa P Edwards, Ian Conlon, Anders G Nelson, James P Evans, Arlene M Davis, Catherine Zimmer, Bryan J Weiner Genome Medicine 2013, 5:3 (25 January 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

In the first study of its kind, a survey of US biobanks reveals the diverse reasons for their establishment, the samples stored, usage, and funding, with implications for utilization and government.

11.

Methodology   Open Access Highly Accessed

The U.S. training institute for dissemination and implementation research in health

Helen I Meissner, Russell E Glasgow, Cynthia A Vinson, David Chambers, Ross C Brownson, Lawrence W Green, Alice S Ammerman, Bryan J Weiner, Brian Mittman Implementation Science 2013, 8:12 (24 January 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access Highly Accessed

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

Timothy R Gershon, Andrew J Crowther, Andrey Tikunov, Idoia Garcia, Ryan Annis, Hong Yuan, C Miller, Jeffrey Macdonald, James Olson, Mohanish Deshmukh Cancer & Metabolism 2013, 1:2 (23 January 2013)

Abstract | Full text | PDF |  Editor’s summary

The Warburg effect, where cancer cells switch to aerobic glycolysis for their metabolic requirements, was observed in normal cerebellum development, as well as in medulloblastoma where it contributed to tumorogenesis.

13.

Review   Open Access

Comparing effects of tobacco use prevention modalities: need for complex system models

Steve Sussman, David Levy, Kristen Hassmiller Lich, Crystal W Cené, Mimi M Kim, Louise A Rohrbach, Frank J Chaloupka Tobacco Induced Diseases 2013, 11:2 (22 January 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access Highly Accessed

Comparison of outcomes for veterans receiving dialysis care from VA and non-VA providers

Virginia Wang, Matthew L Maciejewski, Uptal D Patel, Karen M Stechuchak, Denise M Hynes, Morris Weinberger BMC Health Services Research 2013, 13:26 (18 January 2013)

Abstract | Full text | PDF | PubMed

15.

Software   Open Access Highly Accessed

The taxonomic name resolution service: an online tool for automated standardization of plant names

Brad Boyle, Nicole Hopkins, Zhenyuan Lu, Juan Antonio Raygoza Garay, Dmitry Mozzherin, Tony Rees, Naim Matasci, Martha L Narro, William H Piel, Sheldon J Mckay, Sonya Lowry, Chris Freeland, Robert K Peet, Brian J Enquist BMC Bioinformatics 2013, 14:16 (16 January 2013)

Abstract | Full text | PDF | PubMed

16.

Research article   Open Access Highly Accessed

Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study

Megan D Fesinmeyer, Kari E North, Unhee Lim, Petra Bůžková, Dana C Crawford, Jeffrey Haessler, Myron D Gross, Jay H Fowke, Robert Goodloe, Shelley-Ann Love, Misa Graff, Christopher S Carlson, Lewis H Kuller, Tara C Matise, Ching-Ping Hong, Brian E Henderson, Melissa Allen, Rebecca R Rohde, Ping Mayo, Nathalie Schnetz-Boutaud, Kristine R Monroe, Marylyn D Ritchie, Ross L Prentice, Lawrence N Kolonel, JoAnn E Manson, James Pankow, Lucia A Hindorff, Nora Franceschini, Lynne R Wilkens, Christopher A Haiman, Loic Le Marchand, Ulrike Peters et al. BMC Medical Genetics 2013, 14:6 (11 January 2013)

Abstract | Full text | PDF | PubMed

17.

Research   Open Access Highly Accessed

Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants

Genevieve G Fouda, Tatenda Mahlokozera, Jesus F Salazar-Gonzalez, Maria G Salazar, Gerald Learn, Surender B Kumar, S Moses Dennison, Elizabeth Russell, Katherine Rizzolo, Frederick Jaeger, Fangping Cai, Nathan A Vandergrift, Feng Gao, Beatrice Hahn, George M Shaw, Christina Ochsenbauer, Ronald Swanstrom, Steve Meshnick, Victor Mwapasa, Linda Kalilani, Susan Fiscus, David Montefiori, Barton Haynes, Jesse Kwiek, S Munir Alam, Sallie R Permar Retrovirology 2013, 10:3 (10 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

There was no difference in the efficiency of epithelial cell interactions between Env virus variants from the breast milk of transmitting and nontransmitting mothers. Moreover, there was similar efficiency of DC-mediated trans-infection, CCR5-usage, target cell fusion, and infectivity between HIV-1 Env-pseudoviruses from nontransmitting mothers and postnatal T/F viruses.

18.

Review   Open Access

Resolution of complex ends by non-homologous end joining - better to be lucky than good?

Natasha Tiffany Strande, Crystal Ann Waters, Dale A Ramsden Genome Integrity 2012, 3:10 (31 December 2012)

Abstract | Full text | PDF | PubMed

19.

Research article   Open Access

Genome-wide association Scan of dental caries in the permanent dentition

Xiaojing Wang, John R Shaffer, Zhen Zeng, Ferdouse Begum, Alexandre R Vieira, Jacqueline Noel, Ida Anjomshoaa, Karen T Cuenco, Myoung-Keun Lee, James Beck, Eric Boerwinkle, Marilyn C Cornelis, Frank B Hu, David R Crosslin, Cathy C Laurie, Sarah C Nelson, Kimberly F Doheny, Elizabeth W Pugh, Deborah E Polk, Robert J Weyant, Richard Crout, Daniel W McNeil, Daniel E Weeks, Eleanor Feingold, Mary L Marazita BMC Oral Health 2012, 12:57 (21 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A number of novel genes potentially linked to caries susceptibility and resistance have been identified, several of them involved in common signalling pathways, opening the horizon for new approaches to overcoming this disease

20.

Software   Open Access Highly Accessed

CpGAVAS, an integrated web server for the annotation, visualization, analysis, and GenBank submission of completely sequenced chloroplast genome sequences

Chang Liu, Linchun Shi, Yingjie Zhu, Haimei Chen, Jianhui Zhang, Xiaohan Lin, Xiaojun Guan BMC Genomics 2012, 13:715 (20 December 2012)

Abstract | Full text | PDF | PubMed

21.

Research   Open Access

Associations of adult physical activity with perceived safety and police-recorded crime: the Multi-ethnic Study of Atherosclerosis

Kelly R Evenson, Richard Block, Ana V Roux, Aileen P McGinn, Fang Wen, Daniel A Rodríguez International Journal of Behavioral Nutrition and Physical Activity 2012, 9:146 (17 December 2012)

Abstract | Full text | PDF | PubMed

22.

Short report   Open Access

Multivariate methods and software for association mapping in dose-response genome-wide association studies

Chad C Brown, Tammy M Havener, Marisa Wong Medina, Ronald M Krauss, Howard L McLeod, Alison A Motsinger-Reif BioData Mining 2012, 5:21 (12 December 2012)

Abstract | Provisional PDF | PubMed |  Editor’s summary

The multivariate analysis of variance method (MANOVA) is superior to other methods for association mapping in dose-response genome-wide association studies when applied to a simulation study.

23.

Research article   Open Access

Bayesian methods in clinical trials: a Bayesian analysis of ECOG trials E1684 and E1690

Joseph G Ibrahim, Ming-Hui Chen, Haitao Chu BMC Medical Research Methodology 2012, 12:183 (29 November 2012)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access Highly Accessed

Community perceptions of malaria and vaccines in two districts of Mozambique

Allison Bingham, Felisbela Gaspar, Kathryn Lancaster, Juliana Conjera, Yvette Collymore, Antoinette Ba-Nguz Malaria Journal 2012, 11:394 (28 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A malaria vaccine is not yet available, but planning is underway for a possible introduction. This study explored sociocultural and health communications issues among individuals at the community level who are likely to influence decisions about vaccine use. A communications strategy would need to build on existing immunization efforts and use trusted sources¿including current government dissemination arrangements¿to deliver health information.

25.

Study protocol   Open Access

Oral cleft prevention program (OCPP)

George L Wehby, Norman Goco, Danilo Moretti-Ferreira, Temis Felix, Antonio Richieri-Costa, Carla Padovani, Fernanda Queiros, Camilla Vila Guimaraes, Rui Pereira, Steve Litavecz, Tyler Hartwell, Hrishikesh Chakraborty, Lorette Javois, Jeffrey C Murray BMC Pediatrics 2012, 12:184 (26 November 2012)

Abstract | Full text | PDF | PubMed

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