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351.

Research   Open Access

Genome-wide analysis reveals rapid and dynamic changes in miRNA and siRNA sequence and expression during ovule and fiber development in allotetraploid cotton (Gossypium hirsutum L.)

Mingxiong Pang, Andrew W Woodward, Vikram Agarwal, Xueying Guan, Misook Ha, Vanitharani Ramachandran, Xuemei Chen, Barbara A Triplett, David M Stelly, Z Jeffrey Chen Genome Biology 2009, 10:R122 (4 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Rapid and dynamic changes in the expression of small RNAs are seen during ovule and fiber development in allotetraploid cotton.

352.

Research   Open Access

An intelligent listening framework for capturing encounter notes from a doctor-patient dialog

Jeffrey G Klann, Peter Szolovits BMC Medical Informatics and Decision Making 2009, 9(Suppl 1):S3 (3 November 2009)

Abstract | Full text | PDF | PubMed

353.

Poster presentation   Open Access

P09-20 LB. Ultra-deep sequencing of full-length HIV-1 genomes identifies rapid viral evolution during acute infection

MR Henn, C Boutwell, N Lennon, K Power, C Malboeuf, P Charlebois, A Gladden, J Levin, M Casali, L Philips, A Berlin, A Berical, R Erlich, S Anderson, H Streeck, M Kemper, E Ryan, Y Wang, L Green, K Axten, Z Brumme, C Brumme, C Russ, E Rosenberg, H Jessen, M Altfeld, C Nusbaum, B Walker, B Birren, TM Allen Retrovirology 2009, 6(Suppl 3):P400 (22 October 2009)

Full text | PDF

354.

Poster presentation   Open Access

P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity

CL Boutwell, A Schneidewind, Z Brumme, M Brockman, H Streeck, C Brumme, T Dudek, K Kane, M Kemper, B Walker, M Altfeld, T Allen Retrovirology 2009, 6(Suppl 3):P399 (22 October 2009)

Full text | PDF

355.

Poster presentation   Open Access

P16-41. Evidence for in vivo immune selection pressure exerted by HLA class I restricted CTL responses to anti-sense encoded HIV sequences

CT Berger, J Carlson, CJ Brumme, ZL Brumme, K Hartman, LM Henry, C Kadie, MA Brockman, R Harrigan, D Heckerman, C Brander Retrovirology 2009, 6(Suppl 3):P270 (22 October 2009)

Full text | PDF

356.

Poster presentation   Open Access

P16-31. Skewed HIV-1-specific CD4+ Th2 helper cell contribution in progressive HIV-1 infection

M Chevalier, A Pyo, JS Jolin, M Addo, DS Kwon, I Toth, B Walker, H Streeck Retrovirology 2009, 6(Suppl 3):P260 (22 October 2009)

Full text | PDF

357.

Poster presentation   Open Access

P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection

M Angin, H Streeck, F Wen, A Pyo, A Trocha, I Toth, D Kwon, F Pereyra, G Alter, M Altfeld, BD Walker, MM Addo Retrovirology 2009, 6(Suppl 3):P247 (22 October 2009)

Full text | PDF

358.

Poster presentation   Open Access

P16-12. Relative dominance of Gag-specific cytotoxic T lymphocytes is associated with viral load inversely in HIV-1 clade B' infected Chinese

M Jia, J Chen, K Hong, S Liu, X Zhang, H Zhao, M Altfeld, B Walker, X Yu, Y Shao Retrovirology 2009, 6(Suppl 3):P241 (22 October 2009)

Full text | PDF

359.

Poster presentation   Open Access

P16-08. Combined blockade of the PD-1 and IL-10 pathways synergistically enhance HIV-specific CD4 T cell functions

F Porichis, DS Kwon, DP Tighe, DF Pavlik, DG Kavanagh, GJ Freeman, BD Walker, DE Kaufmann Retrovirology 2009, 6(Suppl 3):P237 (22 October 2009)

Full text | PDF

360.

Poster presentation   Open Access

P16-07. HLA-B1302 is associated with viral control in clade CRF01_AE HIV-1 infection in Thailand

U Hempel, S Buranapraditkun, P Chatkulkawin, P Pitakpolrat, LC Phillips, RL Allgaier, S Lorenzen, WH Hildebrand, T Leitner, P Matthews, P Goulder, BD Walker, K Ruxrungtham, TM Allen Retrovirology 2009, 6(Suppl 3):P236 (22 October 2009)

Full text | PDF

361.

Poster presentation   Open Access

P10-11. NK cells do not accumulate at sites of HIV-replication but show increased activation

R Luteijn, A Nolting, J van Lunzen, M Altfeld, G Alter Retrovirology 2009, 6(Suppl 3):P142 (22 October 2009)

Full text | PDF

362.

Poster presentation   Open Access

P10-01. MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction

A Nolting, R Luteijn, A Dugast, M Carrington, S Rihn, K Kane, S Jost, I Toth, G Faetkenheuer, P Hartmann, M Altfeld, G Alter Retrovirology 2009, 6(Suppl 3):P132 (22 October 2009)

Full text | PDF

363.

Poster presentation   Open Access

P09-11. Reduced replication capacity of NL4-3 chimeric viruses encoding RT-Integrase sequences from HIV-1 elite controllers

C Li, ZL Brumme, T Miura, PC Rosato, J Sela, CJ Brumme, D Heckerman, F Pereyra, BD Walker, MA Brockman Retrovirology 2009, 6(Suppl 3):P124 (22 October 2009)

Full text | PDF

364.

Poster presentation   Open Access

P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication

C Oniangue-Ndza, A Schneidewind, MA Brockman, ZL Brumme, CL Boutwell, YE Wang, CJ Brumme, KA Power, AD Gladden, M Kemper, S Le Gall, H Streeck, G Alter, M Altfeld, D Heckerman, BD Walker, TM Allen Retrovirology 2009, 6(Suppl 3):P123 (22 October 2009)

Full text | PDF

365.

Poster presentation   Open Access

P09-03. HLA class I alleles impact on HIV-1 disease progression by interacting with immunoregulatory HLA receptors on dendritic cells

J Huang Retrovirology 2009, 6(Suppl 3):P116 (22 October 2009)

Full text | PDF

366.

Oral presentation   Open Access

S04-06 OA. Polyvalent Gag-specific CD8 T-cells with enhanced functional properties are enriched in HIV-1 clade C infected individuals with lower viral loads

B Julg, KL Williams, S Reddy, K Bishop, PJ Goulder, T Ndung'u, BD Walker Retrovirology 2009, 6(Suppl 3):O48 (22 October 2009)

Full text | PDF

367.

Oral presentation   Open Access

SO4-05 OA. The intracellular production of HIV antigenic peptides is guided by predictable motifs and can be altered: implications for immunogen design

E Lazaro, S Zhang, M Zhang, S Martinez, D Heckerman, BD Walker, S Le Gall Retrovirology 2009, 6(Suppl 3):O47 (22 October 2009)

Full text | PDF

368.

Oral presentation   Open Access

S03-06 OA. Rapid perforin upregulation by CD8 T cells in elite controllers as a correlate of immune-mediated control of HIV replication

AR Hersperger, F Pereyra, K Demers, P Sheth, LY Shin, B Rodriguez, SF Sieg, L Teixeira-Johnson, PA Goepfert, MM Lederman, R Kaul, G Makedonas, BD Walker, MR Betts Retrovirology 2009, 6(Suppl 3):O45 (22 October 2009)

Full text | PDF

369.

Oral presentation   Open Access

OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules

H Streeck, D Kwon, JS Jolin, K Trocha, M Chevalier, T Caron, K Law, A Pyo, I Toth, DE Kaufmann, SJ Rodig, BD Walker, M Altfeld Retrovirology 2009, 6(Suppl 3):O22 (22 October 2009)

Full text | PDF

370.

Oral presentation   Open Access

OA011-05. TLR-mediated pDC responses to HIV-1 ligands

J Chang, S Kulkarni, A Meier, RJ Lindsay, S Bazner, JD Lifson, RJ Bosch, M Carrington, M Altfeld Retrovirology 2009, 6(Suppl 3):O11 (22 October 2009)

Full text | PDF

371.

Introduction   Open Access

Highlights from the 5th International Society for Computational Biology Student Council Symposium at the 17th Annual International Conference on Intelligent Systems for Molecular Biology and the 8th European Conference on Computational Biology

Thomas Abeel, Jeroen de Ridder, Lucia Peixoto BMC Bioinformatics 2009, 10(Suppl 13):I1 (19 October 2009)

Full text | PDF | PubMed | Cited on BioMed Central

372.

Method   Open Access Highly Accessed

Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts

Joshua Z Levin, Michael F Berger, Xian Adiconis, Peter Rogov, Alexandre Melnikov, Timothy Fennell, Chad Nusbaum, Levi A Garraway, Andreas Gnirke Genome Biology 2009, 10:R115 (16 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Combining next-generation sequencing with capture of sequences from a relevant subset of a transcriptome produces an enhanced view of this subset

373.

Research article   Open Access

The l1-l2 regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines

Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri, Luigi Varesio BMC Genomics 2009, 10:474 (15 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

374.

Research   Open Access Highly Accessed

A mechanistic approach for accurate simulation of village scale malaria transmission

Arne Bomblies, Jean-Bernard Duchemin, Elfatih AB Eltahir Malaria Journal 2009, 8:223 (2 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This paper sets out to investigate whether a detailed description of the hydrology around villages in the Sahel can improve models of malaria transmission based solely on climatological parameters. This is a pilot study and based only on two villages.

375.

Method   Open Access Highly Accessed

ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads

Iain MacCallum, Dariusz Przybylski, Sante Gnerre, Joshua Burton, Ilya Shlyakhter, Andreas Gnirke, Joel Malek, Kevin McKernan, Swati Ranade, Terrance P Shea, Louise Williams, Sarah Young, Chad Nusbaum, David B Jaffe Genome Biology 2009, 10:R103 (1 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Allpaths2, a method for accurately assembling small genomes with high continuity using short paired reads.

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