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FIOCRUZ is the most prominent science and technology institution in health in Latin America, attached to the Brazilian Ministry of Health. Its main purpose is to improve the population health and reduce social inequalities through a range of activities which include research development, production of vaccines, education and training of human resources and the implementation of social programs.

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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Fundação Oswaldo Cruz / Far-Manguinhos

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1.

Research article   Open Access

Prevalence of arterial hypertension among Brazilian adolescents: systematic review and meta-analysis

Erika Magliano, Luciane Guedes, Evandro Silva Coutinho, Katia Bloch BMC Public Health 2013, 13:833 (11 September 2013)

Abstract | Full text | PDF | PubMed

2.

Research article   Open Access Highly Accessed

Anticonvulsant activity of bone marrow cells in electroconvulsive seizures in mice

Enéas Ferrazoli, Miriam Blanco, Simone Bittencourt, André Luis Lacerda Bachi, Luciana Bahia, Milena Botelho Pereira Soares, Ricardo Ribeiro-dos-Santos, Luiz Mello, Beatriz Longo BMC Neuroscience 2013, 14:97 (6 September 2013)

Abstract | Full text | PDF | PubMed

3.

Research   Open Access

The Panamanian health research system: a baseline analysis for the construction of a new phase

Luz I Romero, Cristiane Quental Health Research Policy and Systems 2013, 11:33 (4 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access

Trypanosoma cruzi mitochondrial swelling and membrane potential collapse as primary evidence of the mode of action of naphthoquinone analogues

Kelly Salomão, Natalia A De Santana, Maria Teresa Molina, Solange L De Castro, Rubem F S Menna-Barreto BMC Microbiology 2013, 13:196 (3 September 2013)

Abstract | Full text | PDF | PubMed

5.

Research   Open Access

High levels of IgG3 anti ICB2-5 in Plasmodium vivax-infected individuals who did not develop symptoms

Fernanda G Versiani, Maria EM Almeida, Gisely C Melo, Francivaldo OL Versiani, Patrícia P Orlandi, Luís André M Mariúba, Leidiane A Soares, Luciana P Souza, Antonio A da Silva Balieiro, Wuelton M Monteiro, Fabio TM Costa, Hernando A del Portillo, Marcus VG Lacerda, Paulo A Nogueira Malaria Journal 2013, 12:294 (27 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

It is more frequently recognized that Plasmodium vivax is not that benign parasite it has long been described as. The main objective of the study was to examine antibody responses to a P. vivax vaccine candidate and associations with clinical protection. This is the first study that has attempted to directly correlate IgG subclass responses to P. vivax MSP-1 with clinical protection.

6.

Research   Open Access

Nitric oxide synthase expression correlates with death in an experimental mouse model of dengue with CNS involvement

Kátia Paulino Ribeiro de Souza, Emanuele Silva, Eliseu de Oliveira Rocha, Leandra Figueiredo, Camila de Almeida-Leite, Rosa Maria Esteves Arantes, Juliana de Assis Silva Gomes, Gustavo Ferreira, Jaquelline de Oliveira, Erna Kroon, Marco Campos Virology Journal 2013, 10:267 (26 August 2013)

Abstract | Full text | PDF | PubMed

7.

Research   Open Access Highly Accessed

Use of a colorimetric (DELI) test for the evaluation of chemoresistance of Plasmodium falciparum and Plasmodium vivax to commonly used anti-plasmodial drugs in the Brazilian Amazon

Lilian R Pratt-Riccio, Yonne F Chehuan, Maria Siqueira, Maria das Graças Alecrim, Cesare Bianco-Junior, Pierre Druilhe, Philippe Brasseur, Maria de Fátima Ferreira-da-Cruz, Leonardo JM Carvalho, Cláudio T Daniel-Ribeiro Malaria Journal 2013, 12:281 (12 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Non-isotopic in vitro assays are important laboratory tools to monitor drug-resistant malaria. The authors report on the field application of DELI test in Brazilian Amazon. This assay has been developed as a reproducible and reliable alternative to tritium-labeled-hypoxanthine incorporation assay, and several earlier reports have attested its feasibility in the field.

8.

Research   Open Access

The compositional landscape of minicircle sequences isolated from active lesions and scars of American cutaneous leishmaniasis

Eduardo Henrique Rodrigues, Fábia da Silva Soares, Roberto Werkhäuser, Maria Edileuza F de Brito, Octavio Fernandes, Frederico G Coutinho Abath, Adeilton Brandão Parasites & Vectors 2013, 6:228 (7 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Development of a dictionary of nucleotide words based on minicircle sequences allows the comparison of segments of the Leishmania mitochondrial genome directly from human biological samples without the need for cultivation. Image: Word cloud.

9.

Research   Open Access Highly Accessed

Phylogeography and evolutionary history of hepatitis B virus genotype F in Brazil

Francisco CA Mello, Oscar C Araujo, Barbara V Lago, Ana Rita C Motta-Castro, Marcia Terezinha B Moraes, Selma A Gomes, Gonzalo Bello, Natalia M Araujo Virology Journal 2013, 10:236 (16 July 2013)

Abstract | Full text | PDF | PubMed

10.

Research   Open Access

Seroprevalence and risk factors of toxoplasmosis in cattle from extensive and semi-intensive rearing systems at Zona da Mata, Minas Gerais state, Southern Brazil

Hugo Fajardo, Sthefane D’ávila, Ronaldo Bastos, Carolina Cyrino, Michelle de Lima Detoni, João Garcia, Leandro das Neves, José Nicolau, Maria Regina Amendoeira Parasites & Vectors 2013, 6:191 (25 June 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study analyses the seroprevalence of toxoplasmosis in cattle from farms with extensive or semi-intensive rearing systems and identifies associated risk factors, through an epidemiological investigation. Our results may contribute to the development of preventive strategies in Brazil and other developing countries. Image: Cattle farm with semi-intensive rearing system at Zona da Mata, Minas Gerais, Southern Brazil.

11.

Research   Open Access

The eukaryotic translation initiation factor 3 subunit L protein interacts with Flavivirus NS5 and may modulate yellow fever virus replication

Ana TS Morais, Ana CB Terzian, Danilo VB Duarte, Roberta VM Bronzoni, Maria CFS Madrid, Arieli F Gavioli, Laura HVG Gil, Amanda G Oliveira, Cleslei F Zanelli, Sandro R Valentini, Paula Rahal, Mauricio L Nogueira Virology Journal 2013, 10:205 (22 June 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

American tegumentary leishmaniasis caused by Leishmania (Viannia) braziliensis: assessment of parasite genetic variability at intra- and inter-patient levels

Fernanda S Oliveira, Cláudia M Valete-Rosalino, Sandro JB Pacheco, Filipe Costa, Armando O Schubach, Raquel S Pacheco Parasites & Vectors 2013, 6:189 (20 June 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

We investigated the genetic variability of L. (V.) braziliensis at intra- and inter-patient levels of individuals with distinct clinical manifestations of ATL using LSSP-PCR and phenetic analyses. The results revealed that intrapatient genetic variability was less pronounced than that between different patients. Image: Conceptual model proposed by Pacheco RS and Oliveira FS to better understand the genetic complexity of Leishmania (Viannia) braziliensis at intra- and inter-patient levels.

13.

Research article   Open Access

Individual and contextual factors of influence on adherence to antiretrovirals among people attending public clinics in Rio de Janeiro, Brazil

Homaira Hanif, Francisco I Bastos, Monica Malta, Neilane Bertoni, Pamela J Surkan, Peter J Winch, Deanna Kerrigan BMC Public Health 2013, 13:574 (13 June 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

An analysis of actions to promote health in underprivileged urban areas: a case in Brazil

Érika dos Reis Moreira, Gisele O’Dwyer BMC Family Practice 2013, 14:80 (13 June 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access

Prevalence and incidence of dengue virus and antibody placental transfer during late pregnancy in central Brazil

Angela FLT Argolo, Valéria CR Féres, Lucimeire A Silveira, Anna Carolina M Oliveira, Luiz A Pereira, João Bosco Júnior, Cynthia Braga, Celina MT Martelli BMC Infectious Diseases 2013, 13:254 (31 May 2013)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access

Prevalence of anemia and associated factors among indigenous children in Brazil: results from the First National Survey of Indigenous People’s Health and Nutrition

Maurício S Leite, Andrey M Cardoso, Carlos EA Coimbra, James R Welch, Silvia A Gugelmin, Pedro Cabral I Lira, Bernardo L Horta, Ricardo Santos, Ana Escobar Nutrition Journal 2013, 12:69 (28 May 2013)

Abstract | Full text | PDF | PubMed

17.

Research article   Open Access

Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct saliva-induced cellular recruitment into BALB/c mice ear

Vanessa Carregaro, Diego Luis Costa, Claudia Brodskyn, Aldina Maria Barral, Manuel Barral-Netto, Fernando Q Cunha, João Santana Silva BMC Microbiology 2013, 13:102 (8 May 2013)

Abstract | Full text | PDF | PubMed

18.

Research   Open Access

Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria

Yuri C Martins, Leah Clemmer, Pamela Orjuela-Sánchez, Graziela M Zanini, Peng Kai Ong, John A Frangos, Leonardo JM Carvalho Malaria Journal 2013, 12:138 (24 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper presents original and interesting data on the cardiac effect of experimental cerebral malaria in mice, and that nimodipine at low doses shows a safe profile in terms of cardiovascular effects.

19.

Research article   Open Access

A cross-sectional analysis of women’s mental health problems: examining the association with different types of violence among a sample of Brazilian mothers

Joviana Avanci, Simone Assis, Raquel Oliveira BMC Women's Health 2013, 13:20 (15 April 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

Research article   Open Access Highly Accessed

Candidatus Liberibacter americanus induces significant reprogramming of the transcriptome of the susceptible citrus genotype

Valéria Mafra, Polyana K Martins, Carolina S Francisco, Marcelo Ribeiro-Alves, Juliana Freitas-Astúa, Marcos A Machado BMC Genomics 2013, 14:247 (12 April 2013)

Abstract | Full text | PDF | PubMed

21.

Short report   Open Access

Does the trematode Centrocestus formosanus affect the locomotory activity of the mollusc Melanoides tuberculatus?

Everton Gustavo Nunes dos Santos, Viviane da Silva Costa, Cláudia Portes Santos Parasites & Vectors 2013, 6:92 (10 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The aim of the work was to evaluate the locomotory activity of uninfected Melanoides tuberculatus (Mollusca) compared with those naturally infected with Centrocestus. formosanus (Trematoda) using an image analysis system. Image: Image analysis biomonitoring system composed of an illuminating cabin and a recording cabin holding a fixed analogue video camera.

22.

Research   Open Access

Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions

Thiago Affonso Belinato, Ademir Jesus Martins, José Bento Pereira Lima, Denise Valle Parasites & Vectors 2013, 6:83 (4 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Chitin synthesis inhibitors are effective against Ae. aegypti populations resistant to neurotoxic insecticides and other mosquitoes of public health importance. Image: Aedes aegypti mosquito during blood-feeding.

23.

Research   Open Access

Nutritional status of indigenous children: findings from the First National Survey of Indigenous People’s Health and Nutrition in Brazil

Bernardo L Horta, Ricardo Ventura Santos, James R Welch, Andrey M Cardoso, Janaína Vieira dos Santos, Ana Marlúcia Oliveira Assis, Pedro CI Lira, Carlos EA Coimbra Jr International Journal for Equity in Health 2013, 12:23 (3 April 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Research   Open Access

LUMINEX®: a new technology for the simultaneous identification of five Entamoeba spp. commonly found in human stools

Helena Lúcia Carneiro Santos, Kakali Bandyopadhyay, Rebecca Bandea, Regina Helena Saramago Peralta, José Mauro Peralta, Alexandre Januário Da Silva Parasites & Vectors 2013, 6:69 (15 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The goal of this study was to develop a rapid, high-throughput multiplex screening method for detection and differentiation of Entamoeba spp. The assay was based on the Luminex platform and should strengthen the diagnostic identification of mixed infections. Image: Luminex technology for rapid, high-throughput multiplexed nucleic acid detection.

25.

Research   Open Access

Transcriptome exploration of the sex pheromone gland of Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae)

Natalia González-Caballero, Jesus G Valenzuela, José MC Ribeiro, Patricia Cuervo, Reginaldo P Brazil Parasites & Vectors 2013, 6:56 (7 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study constitutes the first transcriptomic analysis exploring the repertoire of genes expressed in the tissue containing the L. longipalpis pheromone gland. Using a comparative approach, a set of molecules potentially present in the mevalonate pathway emerge as interesting subjects for further study regarding their association to pheromone biosynthesis. Image: The stereoscope image of a L. longipalpis male showing the 4th abdominal segment with pheromone gland

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