1.
Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct saliva-induced cellular recruitment into BALB/c mice ear
Vanessa
Carregaro,
Diego Luis
Costa,
Claudia
Brodskyn,
Aldina Maria
Barral,
Manuel
Barral-Netto,
Fernando
Q
Cunha,
João Santana
Silva
BMC Microbiology 2013, 13 :102 (8 May 2013)
Abstract | Full text | PDF | PubMed
2.
Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria
Yuri
C
Martins,
Leah
Clemmer,
Pamela
Orjuela-Sánchez,
Graziela
M
Zanini,
Peng Kai
Ong,
John
A
Frangos,
Leonardo
JM
Carvalho
Malaria Journal 2013, 12 :138 (24 April 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
This paper presents original and interesting data on the cardiac effect of experimental cerebral malaria in mice, and that nimodipine at low doses shows a safe profile in terms of cardiovascular effects.
3.
A cross-sectional analysis of women’s mental health problems: examining the association with different types of violence among a sample of Brazilian mothers
Joviana
Avanci,
Simone
Assis,
Raquel
Oliveira
BMC Women's Health 2013, 13 :20 (15 April 2013)
Abstract | Full text | PDF | PubMed
4.
Candidatus Liberibacter americanus induces significant reprogramming of the transcriptome of the susceptible citrus genotype
Valéria
Mafra,
Polyana
K
Martins,
Carolina
S
Francisco,
Marcelo
Ribeiro-Alves,
Juliana
Freitas-Astúa,
Marcos
A
Machado
BMC Genomics 2013, 14 :247 (12 April 2013)
Abstract | Full text | PDF | PubMed
5.
Does the trematode Centrocestus formosanus affect the locomotory activity of the mollusc Melanoides tuberculatus ?
Everton Gustavo Nunes
dos Santos,
Viviane da Silva
Costa,
Cláudia Portes
Santos
Parasites & Vectors 2013, 6 :92 (10 April 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The aim of the work was to evaluate the locomotory activity of uninfected Melanoides tuberculatus (Mollusca) compared with those naturally infected with Centrocestus. formosanus (Trematoda) using an image analysis system. Image: Image analysis biomonitoring system composed of an illuminating cabin and a recording cabin holding a fixed analogue video camera.
6.
Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
Thiago Affonso
Belinato,
Ademir Jesus
Martins,
José Bento Pereira
Lima,
Denise
Valle
Parasites & Vectors 2013, 6 :83 (4 April 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Chitin synthesis inhibitors are effective against Ae. aegypti populations resistant to neurotoxic insecticides and other mosquitoes of public health importance. Image: Aedes aegypti mosquito during blood-feeding.
7.
Nutritional status of indigenous children: findings from the First National Survey of Indigenous People’s Health and Nutrition in Brazil
Bernardo
L
Horta,
Ricardo Ventura
Santos,
James
R
Welch,
Andrey
M
Cardoso,
Janaína Vieira
dos Santos,
Ana Marlúcia Oliveira
Assis,
Pedro
CI
Lira,
Carlos
EA
Coimbra Jr
International Journal for Equity in Health 2013, 12 :23 (3 April 2013)
Abstract | Full text | PDF | PubMed
8.
LUMINEX®: a new technology for the simultaneous identification of five Entamoeba spp. commonly found in human stools
Helena Lúcia Carneiro
Santos,
Kakali
Bandyopadhyay,
Rebecca
Bandea,
Regina Helena Saramago
Peralta,
José Mauro
Peralta,
Alexandre Januário
Da Silva
Parasites & Vectors 2013, 6 :69 (15 March 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The goal of this study was to develop a rapid, high-throughput multiplex screening method for detection and differentiation of Entamoeba spp. The assay was based on the Luminex platform and should strengthen the diagnostic identification of mixed infections. Image: Luminex technology for rapid, high-throughput multiplexed nucleic acid detection.
9.
Transcriptome exploration of the sex pheromone gland of Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae)
Natalia
González-Caballero,
Jesus
G
Valenzuela,
José
MC
Ribeiro,
Patricia
Cuervo,
Reginaldo
P
Brazil
Parasites & Vectors 2013, 6 :56 (7 March 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
This study constitutes the first transcriptomic analysis exploring the repertoire of genes expressed in the tissue containing the L. longipalpis pheromone gland. Using a comparative approach, a set of molecules potentially present in the mevalonate pathway emerge as interesting subjects for further study regarding their association to pheromone biosynthesis. Image: The stereoscope image of a L. longipalpis male showing the 4th abdominal segment with pheromone gland
10.
Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages
Izabela Coimbra
Ibraim,
Rafael Ramiro
de Assis,
Natália Lima
Pessoa,
Marco Antônio
Campos,
Maria Norma
Melo,
Salvatore Joseph
Turco,
Rodrigo Pedro
Soares
Parasites & Vectors 2013, 6 :54 (7 March 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The role of the L. braziliensis and L. infantum LPG during interaction with macrophages was assessed. The polymorphisms of the glycan moieties resulted in differential activation of NFKB and inflammatory mediators, suggesting an important role of LPG in the immune response. Image: Leishmania promastigotes. Cultured promastigotes were placed in glass slides and stained by Giemsa.
11.
Molecular characterization of HTLV-1 gp46 glycoprotein from health carriers and HAM/TSP infected individuals
Aline C A
Mota-Miranda,
Fernanda
K
Barreto,
Maria F C
Amarante,
Everton
Batista,
Joana
P
Monteiro-Cunha,
Lourdes
Farre,
Bernardo
Galvão-Castro,
Luiz C J
Alcantara
Virology Journal 2013, 10 :75 (6 March 2013)
Abstract | Full text | PDF | PubMed
12.
Disseminated intravascular coagulation in a dog naturally infected by Leishmania (Leishmania ) chagasi from Rio de Janeiro – Brazil
Carla
O
Honse,
Fabiano
B
Figueiredo,
Nayro X de
Alencar,
Maria de
Fátima Madeira,
Isabella
DF
Gremião,
Tânia
MP
Schubach
BMC Veterinary Research 2013, 9 :43 (5 March 2013)
Abstract | Full text | PDF | PubMed
13.
Trypsin-like serine peptidase profiles in the egg, larval, and pupal stages of Aedes albopictus
Leonardo
Saboia-Vahia,
André
Borges-Veloso,
Camila
Mesquita-Rodrigues,
Patricia
Cuervo,
Geovane
Dias-Lopes,
Constança
Britto,
Ana Paula de Barros
Silva,
Jose
B
De Jesus
Parasites & Vectors 2013, 6 :50 (27 February 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
In this study, the active trypsin-like serine peptidases profile of pre-imaginal stages of Aedes albopictus were characterized. Egg, larval and pupal stages of this species express a complex proteolytic profile with optimal activity at alkaline pH and over a wide range of temperature. By a comparative analysis of the differential expression of peptidase activities, it was possible to detect and assign specific trypsin activities to each pre-imaginal stage. Image: Trypsin-like serine peptidases profile exhibited by egg, larva and pupa of Aedes albopictus.
14.
Blomia tropicalis Blo t 5 and Blo t 21 recombinant allergens might confer higher specificity to serodiagnostic assays than whole mite extract
Kellyanne dos Anjos
Carvalho,
Osvaldo Pompílio
de Melo-Neto,
Franklin Barbalho
Magalhães,
João Carlos Marques
Ponte,
Filipe Adriano Borba
Felipe,
Mariese Conceição Alves
dos Santos,
Givaneide
dos Santos Lima,
Álvaro Augusto
Cruz,
Carina Silva
Pinheiro,
Lain Carlos
Pontes-de-Carvalho,
Neuza Maria
Alcantara-Neves
BMC Immunology 2013, 14 :11 (27 February 2013)
Abstract | Full text | PDF | PubMed
15.
Phylogeography of the neotropical Anopheles triannulatus complex (Diptera: Culicidae) supports deep structure and complex patterns
Marta
Moreno,
Sara
Bickersmith,
Wesley
Harlow,
Jessica
Hildebrandt,
Sascha
N
McKeon,
Teresa Fernandes
Silva-do-Nascimento,
Jose
R
Loaiza,
Freddy
Ruiz,
Ricardo
Lourenço-de-Oliveira,
Maria AM
Sallum,
Eduardo
S
Bergo,
Gary
N
Fritz,
Richard
C
Wilkerson,
Yvonne
M
Linton,
Maria J Dantur
Juri,
Yadira
Rangel,
Marinete
M
Póvoa,
Lina
A
Gutiérrez-Builes,
Margarita
M
Correa,
Jan
E
Conn
Parasites & Vectors 2013, 6 :47 (22 February 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
We examined the molecular phylogenetic relationships and population structure of the species of the Anopheles triannulatus complex (Anopheles triannulatus s.s., Anopheles halophylus and the putative species Anopheles triannulatus C) using the mitochondrial COI gene, the nuclear white gene and rDNA ITS2. Image: Origin of the samples.
16.
Networking the host immune response in Plasmodium vivax malaria
Vitor
RR
Mendonça,
Artur
TL
Queiroz,
Fabrício
M
Lopes,
Bruno
B
Andrade,
Manoel
Barral-Netto
Malaria Journal 2013, 12 :69 (21 February 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The clinical outcome of an infection is a consequence of the interaction of multiple factors - parasite, environmental and host factors. This study is a network analysis of different clinical presentations of vivax malaria to identify patterns of association between various candidate biomarkers and the clinical outcome.
17.
The current scenario of emergency care policies in Brazil
Gisele
O'Dwyer,
Mariana Teixeira
Konder,
Cristiani Vieira
Machado,
Camila Paes
Alves,
Renan Paes
Alves
BMC Health Services Research 2013, 13 :70 (20 February 2013)
Abstract | Full text | PDF | PubMed
18.
Detection of DENV-4 genotype I from mosquitoes collected in the city of Manaus, Brazil
Mario Luis Garcia
de Figueiredo,
Helda
L
Alfonso,
Alberto Anastacio
Amarilla,
Luiz Tadeu Moraes
Figueiredo,
Victor Hugo
Aquino,
Cristóvão Alves
da Costa,
Sergio Luiz Bessa
Luz
Virology Journal 2013, 10 :60 (19 February 2013)
Abstract | Full text | PDF | PubMed
19.
Determining gestational age for public health care users in Brazil: comparison of methods and algorithm creation
Ana Paula Esteves
Pereira,
Marcos Augusto Bastos
Dias,
Maria Helena
Bastos,
Silvana granado Nogueira
da Gama,
Maria do Carmo
Leal
BMC Research Notes 2013, 6 :60 (13 February 2013)
Abstract | Full text | PDF | PubMed
20.
Clinical and laboratory features that discriminate dengue from other febrile illnesses: a diagnostic accuracy study in Rio de Janeiro, Brazil
Regina
P
Daumas,
Sonia
RL
Passos,
Raquel
VC
Oliveira,
Rita
MR
Nogueira,
Ingebourg
Georg,
Keyla
BF
Marzochi,
Patrícia
Brasil
BMC Infectious Diseases 2013, 13 :77 (8 February 2013)
Abstract | Full text | PDF | PubMed
21.
Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis
Márcia Carvalho
Vilela,
Graciela Kunrath
Lima,
David Henrique
Rodrigues,
Norinne
Lacerda-Queiroz,
Vinicius Sousa Pietra
Pedroso,
Aline Silva
Miranda,
Milene Alvarenga
Rachid,
Erna Geessien
Kroon,
Marco Antônio
Campos,
Mauro Martins
Teixeira,
Johann
Sellner,
Antonio Lucio
Teixeira
BMC Neuroscience 2013, 14 :19 (7 February 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The absence of the chemokine receptor CCR5 in mice inoculated with herpes simplex virus 1 leads to a lower viral load and high neutrophil recruitment, thought to play a role in the pathogenesis of neuroaxonal damage in herpetic encephalitis.
22.
Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity
Sylvia
S
Amaral,
André
G
Oliveira,
Pedro
E
Marques,
Jayane L
D
Quintão,
Daniele
A
Pires,
Rodrigo
R
Resende,
Bruna
R
Sousa,
Juliana
G
Melgaço,
Marcelo
A
Pinto,
Remo
C
Russo,
Ariane K
C
Gomes,
Lidia
M
Andrade,
Rafael
F
Zanin,
Rafaela V
S
Pereira,
Cristina
Bonorino,
Frederico
M
Soriani,
Cristiano
X
Lima,
Denise
C
Cara,
Mauro
M
Teixeira,
Maria
F
Leite,
Gustavo
B
Menezes
Cell Communication and Signaling 2013, 11 :10 (5 February 2013)
Abstract | Full text | PDF | PubMed
23.
Prevalence and risk factors of Hepatitis C virus infection in Brazil, 2005 through 2009: a cross-sectional study
Leila
MMB
Pereira,
Celina
MT
Martelli,
Regina
C
Moreira,
Edgar
Merchan-Hamman,
Airton
T
Stein,
Regina Maria
A
Cardoso,
Gerusa
M
Figueiredo,
Ulisses
R
Montarroyos,
Cynthia
Braga,
Marília
D
Turchi,
Gabriela
Coral,
Deborah
Crespo,
Maria Luiza
C
Lima,
Luis Claudio
A
Alencar,
Marcelo
Costa,
Alex
A
dos Santos,
Ricardo
AA
Ximenes
BMC Infectious Diseases 2013, 13 :60 (1 February 2013)
Abstract | Full text | PDF | PubMed
24.
Accuracy of real-time PCR, Gram stain and culture for Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae meningitis diagnosis
Henry
M
Wu,
Soraia
M
Cordeiro,
Brian
H
Harcourt,
MariadaGloriaS
Carvalho,
Jailton
Azevedo,
Tainara
Q
Oliveira,
Mariela
C
Leite,
Katia
Salgado,
Mitermayer
G
Reis,
Brian
D
Plikaytis,
Thomas
A
Clark,
Leonard
W
Mayer,
Albert
I
Ko,
Stacey
W
Martin,
Joice
N
Reis
BMC Infectious Diseases 2013, 13 :26 (22 January 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Real-time PCR and Gram stain display relative accuracy in diagnosing meningitis when compared with cerebrospinal fluid culture and are less affected by antibiotic presence suggesting that these methods may be useful when antibiotics have been previously administered.
25.
The First National Survey of Indigenous People’s Health and Nutrition in Brazil: rationale, methodology, and overview of results
Carlos EA
Coimbra,
Ricardo Ventura
Santos,
James
R
Welch,
Andrey Moreira
Cardoso,
Mirian Carvalho
de Souza,
Luiza
Garnelo,
Elias
Rassi,
Maj-Lis
Follér,
Bernardo
L
Horta
BMC Public Health 2013, 13 :52 (19 January 2013)
Abstract | Full text | PDF | PubMed
FIOCRUZ is the most prominent science and technology institution in health in Latin America, attached to the Brazilian Ministry of Health. Its main purpose is to improve the population health and reduce social inequalities through a range of activities which include research development, production of vaccines, education and training of human resources and the implementation of social programs.
