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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Weizmann Institute of Science

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51.

Nano Express   Open Access

DNA-directed immobilization of horseradish peroxidase onto porous SiO2 optical transducers

Giorgi Shtenberg, Naama Massad-Ivanir, Sinem Engin, Michal Sharon, Ljiljana Fruk, Ester Segal Nanoscale Research Letters 2012, 7:443 (8 August 2012)

Abstract | Full text | PDF | PubMed

52.

Research   Open Access

Comparative analysis indicates regulatory neofunctionalization of yeast duplicates

Itay Tirosh, Naama Barkai Genome Biology 2007, 8:R50 (5 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Comparison of the expression profiles of S. cerevisiae duplicate pairs with that of their pre-duplication orthologs in C. albicans identified a class of genes that may present cases of regulatory neofunctionalization.

53.

Research article   Open Access Highly Accessed

How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex

Yaki Setty, Chih-Chun Chen, Maria Secrier, Nikita Skoblov, Dimitrios Kalamatianos, Stephen Emmott BMC Systems Biology 2011, 5:154 (30 September 2011)

Abstract | Full text | PDF | PubMed

54.

Research article   Open Access

Diversification of Quiescin sulfhydryl oxidase in a preserved framework for redox relay

Keren Limor-Waisberg, Shifra Ben-Dor, Deborah Fass BMC Evolutionary Biology 2013, 13:70 (19 March 2013)

Abstract | Full text | PDF | PubMed

55.

Research   Open Access Highly Accessed

A catalog of stability-associated sequence elements in 3' UTRs of yeast mRNAs

Reut Shalgi, Michal Lapidot, Ron Shamir, Yitzhak Pilpel Genome Biology 2005, 6:R86 (30 September 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

By analyzing 3' UTR sequences and mRNA decay profiles in yeast, 53 sequence motifs have been identified that may be implicated in stabilization or destabilization of mRNA.

56.

Research   Open Access

Modulation of the transcription regulatory program in yeast cells committed to sporulation

Gilgi Friedlander, Daphna Joseph-Strauss, Miri Carmi, Drora Zenvirth, Giora Simchen, Naama Barkai Genome Biology 2006, 7:R20 (8 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Analysis of the gene expression program in yeast cells suggests that commitment to sporulation involves an active modulation of the gene expression program.

57.

Correspondence   Open Access

Answer to Wang and Luo, "Polyploidization increases meiotic recombination frequency in Arabidopsis: a close look at statistical modelling and data analysis"

Ales Pecinka, Avraham Levy, Ortrun Mittelsten Scheid BMC Biology 2012, 10:31 (18 April 2012)

Abstract | Full text | PDF | PubMed

58.

Research article   Open Access

The evolving doublecortin (DCX) superfamily

Orly Reiner, Frédéric M Coquelle, Bastian Peter, Talia Levy, Anna Kaplan, Tamar Sapir, Irit Orr, Naama Barkai, Gregor Eichele, Sven Bergmann BMC Genomics 2006, 7:188 (26 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

59.

Research article   Open Access Highly Accessed

Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes

Amit Zeisel, Amnon Amir, Wolfgang J Köstler, Eytan Domany BMC Bioinformatics 2010, 11:400 (27 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

60.

Research   Open Access

The society of genes: networks of functional links between genes from comparative genomics

Itai Yanai, Charles DeLisi Genome Biology 2002, 3:research0064-research0064.12 (25 October 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Comparative genomics provides at least three methods for identifying functional links between genes: examination of phylogenetic distributions, analysis of conserved proximity and observations of fusions of genes into a multidomain gene in another organism. We show that the functional networks obtained by applying these methods have different topologies and that the information they provide is largely additive. In particular, the combined networks of functional links contain an average of 57% of an organism's complete genetic complement, uncover substantial portions of known pathways, and suggest the function of previously unannotated genes. In addition, the combined networks are qualitatively different from the networks obtained using individual methods.

61.

Research article   Open Access

Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback

Yonatan Savir, Nir Waysbort, Yaron E Antebi, Tsvi Tlusty, Nir Friedman BMC Systems Biology 2012, 6:111 (27 August 2012)

Abstract | Full text | PDF | PubMed

62.

Research article   Open Access Highly Accessed

Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes

Paz Polak, Eytan Domany BMC Genomics 2006, 7:133 (1 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Alu repeat elements are common upstream of transcription start sites and contain putative binding sites for transcription factors linked to development, evidence for evolution utilizing transposable elements to insert novel binding sites into promoters.

63.

Research   Open Access

FSH regulates acetycholine production by ovarian granulosa cells

Artur Mayerhofer, Lars Kunz, Annette Krieger, Becky Proskocil, Eliot Spindel, Abraham Amsterdam, Gregory A Dissen, Sergio R Ojeda, Ignaz Wessler Reproductive Biology and Endocrinology 2006, 4:37 (17 July 2006)

Abstract | Full text | PDF | PubMed

64.

Research   Open Access

Ancient genomic architecture for mammalian olfactory receptor clusters

Ronny Aloni, Tsviya Olender, Doron Lancet Genome Biology 2006, 7:R88 (1 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A new tool for genome-wide definition of genomic gene clusters conserved in multiple species was applied to olfactory receptors in five mammals, demonstrating that most mammalian olfactory receptor clusters have a common ancestry.

65.

Research article   Open Access

Genetic load and transgenic mitigating genes in transgenic Brassica rapa (field mustard) × Brassica napus (oilseed rape) hybrid populations

Christy W Rose, Reginald J Millwood, Hong S Moon, Murali R Rao, Matthew D Halfhill, Paul L Raymer, Suzanne I Warwick, Hani Al-Ahmad, Jonathan Gressel, C Neal Stewart BMC Biotechnology 2009, 9:93 (31 October 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Brassica rapa (weed) x Brassica napus (crop) transgenic hybrids are less fit than B. rapa in competitive conditions, with crop alleles acting as a negative genetic load opposing transgene introgression, while a mitigating transgene is soon lost from hybrids.

66.

Research article   Open Access Highly Accessed

Coding limits on the number of transcription factors

Shalev Itzkovitz, Tsvi Tlusty, Uri Alon BMC Genomics 2006, 7:239 (19 September 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

67.

Research   Open Access

Live sequence charts to model medical information

Eric Aslakson, Smadar Szekely, Suzanne D Vernon, Lucinda Bateman, Jan Baumbach, Yaki Setty Theoretical Biology and Medical Modelling 2012, 9:22 (15 June 2012)

Abstract | Full text | PDF | PubMed

68.

Research article   Open Access

Robust Control of PEP Formation Rate in the Carbon Fixation Pathway of C4 Plants by a Bi-functional Enzyme

Yuval Hart, Avraham E Mayo, Ron Milo, Uri Alon BMC Systems Biology 2011, 5:171 (24 October 2011)

Abstract | Full text | PDF | PubMed | 1 comment

69.

Research article   Open Access

Search for computational modules in the C. elegans brain

Markus Reigl, Uri Alon, Dmitri B Chklovskii BMC Biology 2004, 2:25 (2 December 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Over-represented patterns of inter-connectivity in the C. elegans nervous system are candidates for computational modules that perform stereotypical functions.

70.

Software   Open Access

Novel definition files for human GeneChips based on GeneAnnot

Francesco Ferrari, Stefania Bortoluzzi, Alessandro Coppe, Alexandra Sirota, Marilyn Safran, Michael Shmoish, Sergio Ferrari, Doron Lancet, Gian Danieli, Silvio Bicciato BMC Bioinformatics 2007, 8:446 (15 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

71.

Database   Open Access Highly Accessed

Expoldb: expression linked polymorphism database with inbuilt tools for analysis of expression and simple repeats

Vineet K Sharma, Anu Sharma, Naveen Kumar, Mamta Khandelwal, Kiran Mandapati, Shirley Horn-Saban, Liora Strichman-Almashanu, Doron Lancet, Samir K Brahmachari, Srinivasan Ramachandran BMC Genomics 2006, 7:258 (13 October 2006)

Abstract | Full text | PDF | PubMed | 1 comment

72.

Research article   Open Access

Environmental variability and modularity of bacterial metabolic networks

Merav Parter, Nadav Kashtan, Uri Alon BMC Evolutionary Biology 2007, 7:169 (23 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

73.

Research article   Open Access Highly Accessed

Discovering local patterns of co - evolution: computational aspects and biological examples

Tamir Tuller, Yifat Felder, Martin Kupiec BMC Bioinformatics 2010, 11:43 (22 January 2010)

Abstract | Full text | PDF | PubMed

74.

Research article   Open Access Highly Accessed

Teratogen-induced alterations in microRNA-34, microRNA-125b and microRNA-155 expression: correlation with embryonic p53 genotype and limb phenotype

Keren Gueta, Natali Molotski, Natalie Gerchikov, Eyal Mor, Shoshana Savion, Amos Fein, Vladimir Toder, Noam Shomron, Arkady Torchinsky BMC Developmental Biology 2010, 10:20 (21 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

75.

Genome databases   Open Access

In-silico human genomics with GeneCards

Gil Stelzer, Irina Dalah, Tsippi Stein, Yigeal Satanower, Naomi Rosen, Noam Nativ, Danit Oz-Levi, Tsviya Olender, Frida Belinky, Iris Bahir, Hagit Krug, Paul Perco, Bernd Mayer, Eugene Kolker, Marilyn Safran, Doron Lancet Human Genomics 2011, 5:709-717 (1 October 2011)

Abstract | Full text | PDF

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