Association of the endothelial protein C receptor ( PROCR) rs867186-G allele with protection from severe malaria
Malaria Journal 2014, 13:105 (17 March 2014)
The authors describe a significant association of SNPs in the endothelial protein C receptor gene and surrounding regions with protection from severe malaria, which strengthens the case for involvement of this receptor in pathology.
Long-term booster schedules with AS03 A-adjuvanted heterologous H5N1 vaccines induces rapid and broad immune responses in Asian adults
Daniel Wai Sing
BMC Infectious Diseases 2014, 14:142 (15 March 2014)
Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria
Malaria Journal 2014, 13:91 (12 March 2014)
Interesting study on the correlation of biomarkers for parasite burden and immune activation with acute kidney injury (AKI) in severe falciparum malaria. The authors convincingly demonstrated that both parasite burden and immune activation via modulation of mononuclear cell adhesion and migration are strongly correlated with kidney dysfunction.
Plaque reduction neutralization antibody test does not accurately predict protection against dengue infection in Ratchaburi cohort, Thailand
Virology Journal 2014, 11:48 (12 March 2014)
Nuclear factor kappa B in urine sediment: a useful indicator to detect acute kidney injury in Plasmodium falciparum malaria
Malaria Journal 2014, 13:84 (7 March 2014)
Acute Kidney Injury is a major factor for the outcome of the survival of the patients.
There is a need for finding out new biomarkers which should be easy, simple and inexpensive to replace serum creatinine estimation, which takes time and is very late to rise. This study is a step in the right direction.
Consent and assent in paediatric research in low-income settings
BMC Medical Ethics 2014, 15:22 (5 March 2014)
Brachytherapy boost in loco-regionally advanced nasopharyngeal carcinoma: a prospective randomized trial of the International Atomic Energy Agency
Radiation Oncology 2014, 9:67 (1 March 2014)
Risk prediction score for death of traumatised and injured children
BMC Pediatrics 2014, 14:60 (28 February 2014)
Clinical audit to enhance safe practice of skilled birth attendants for the fetus with nuchal cord: evidence from a refugee and migrant cohort
BMC Pregnancy and Childbirth 2014, 14:76 (20 February 2014)
Motivations and perceptions of community advisory boards in the ethics of medical research: the case of the Thai-Myanmar border
BMC Medical Ethics 2014, 15:12 (17 February 2014)
A rapid sensitive, flow cytometry-based method for the detection of Plasmodium vivax-infected blood cells
Malaria Journal 2014, 13:55 (14 February 2014)
An antibody-based flow cytometry method to detect Plasmodium vivax-infected reticulocytes in human blood samples. The paper adds to the small tool-kit box for research in Plasmodium vivax malaria.
Comparison of salivary and plasma adiponectin and leptin in patients with metabolic syndrome
Diabetology & Metabolic Syndrome 2014, 6:19 (14 February 2014)
Mass primaquine treatment to eliminate vivax malaria: lessons from the past
Malaria Journal 2014, 13:51 (7 February 2014)
In the past, some countries aiming for vivax malaria eradication deployed mass treatments with primaquine on a massive scale, without prior G6PD testing. In Azerbaijan, Tajikistan, North Afghanistan and DPR Korea eight million people received primaquine treatment to control post-eradication malaria epidemics. These mass primaquine preventive treatment campaigns were conducted by dedicated teams who administered the drugs under supervision and then monitored the population for adverse events. This experience shows that with careful planning and implementation, mass treatment strategies can be used in elimination programmes, with relatively limited and manageable risks.
Introducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau
Malaria Journal 2014, 13:50 (6 February 2014)
Innovative strategies are needed to tackle childhood mortality in the rural tropics, as the state of a febrile child can deteriorate very rapidly and a large number of the deaths in rural areas occur before patients have reached a health care facility. Artesunate suppositories were developed for severely ill children with malaria in rural areas where injectable treatment is not possible for several hours. This study has investigated the acceptability of introducing a combined antimalarial-antibacterial suppository.
Use of the i2b2 research query tool to conduct a matched case–control clinical research study: advantages, disadvantages and methodological considerations
BMC Medical Research Methodology 2014, 14:16 (30 January 2014)
Assessment of emergency medical service of three schemes under the concept “medical emergency care for everybody everywhere”
BMC Public Health 2014, 14(Suppl 1):O31 (29 January 2014)
Development of ambulatory care sensitive conditions (ACSC) in Thai context: hospitalisation rates for ACSC as indicator of access and quality in primary care
BMC Public Health 2014, 14(Suppl 1):O28 (29 January 2014)
Impacts of pH, temperature, and pretreatment method on biohydrogen production from organic wastes by sewage microflora
International Journal of Energy and Environmental Engineering 2014, 5:6 (24 January 2014)
Residual macrovascular risk in 2013: what have we learned?
Cardiovascular Diabetology 2014, 13:26 (24 January 2014)
Female genital mutilation and intimate partner violence in the Ivory Coast
BMC Women's Health 2014, 14:13 (22 January 2014)
Measurement of the levels of leptin, BDNF associated with polymorphisms LEP G2548A, LEPR Gln223Arg and BDNF Val66Met in Thai with metabolic syndrome
Diabetology & Metabolic Syndrome 2014, 6:6 (21 January 2014)
Four years’ monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border
Malaria Journal 2014, 13:23 (15 January 2014)
In vitro sensitivity of a large number of parasite isolates (collected over two periods on the Thai-Myanmar border) to several important anti-malarials, with links to mutations in a range of well characterized resistance-associated genes. They conclude that in vitro artesunate sensitivity of parasites in the region has declined and that multidrug resistance is predominantly associated with mutations in pfmdr1 and pfmrp1.
Silicon balance in human volunteers; a pilot study to establish the variance in silicon excretion versus intake
Nutrition & Metabolism 2014, 11:4 (9 January 2014)
Hand grip strength and associated factors in non-institutionalised men and women 50 years and older in South Africa
BMC Research Notes 2014, 7:8 (7 January 2014)
Efficacy and effectiveness of infant vaccination against chronic hepatitis B in the Gambia Hepatitis Intervention Study (1986–90) and in the nationwide immunisation program
BMC Infectious Diseases 2014, 14:7 (7 January 2014)