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151.

Full Research Paper   Open Access Highly Accessed

Large-scale ruthenium- and enzyme-catalyzed dynamic kinetic resolution of (rac)-1-phenylethanol

Krisztián Bogár, Belén Martín-Matute, Jan-E Bäckvall Beilstein Journal of Organic Chemistry 2007, 3:50 (20 December 2007)

Abstract | Full text | PDF | PubMed | Graphical abstract

152.

Research   Open Access

Age-related subproteomic analysis of mouse liver and kidney peroxisomes

Jia Mi, Itsaso Garcia-Arcos, Ruben Alvarez, Susana Cristobal Proteome Science 2007, 5:19 (27 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

153.

Research   Open Access

Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD

Rochellys Heijtz, Andrey Alexeyenko, F Xavier Castellanos Behavioral and Brain Functions 2007, 3:33 (10 July 2007)

Abstract | Full text | PDF | PubMed

154.

Research article   Open Access Highly Accessed

Primate brain architecture and selection in relation to sex

Patrik Lindenfors, Charles L Nunn, Robert A Barton BMC Biology 2007, 5:20 (10 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Primate brains are subject to selection according to sex, with male competition correlating with evolution of aggression and larger sensory-motor brain regions while female sociality correlates with the evolution of expanded socio-cognitive brain structures.

155.

Software   Open Access Highly Accessed

primetv: a viewer for reconciled trees

Bengt Sennblad, Eva Schreil, Ann-Charlotte Berglund Sonnhammer, Jens Lagergren, Lars Arvestad BMC Bioinformatics 2007, 8:148 (7 May 2007)

Abstract | Full text | PDF | PubMed

156.

Comment   Open Access

Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes?

Anthony M Poole Biology Direct 2006, 1:36 (7 December 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

157.

Research article   Open Access Highly Accessed

Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study

Kristjana Einarsdóttir, Lena U Rosenberg, Keith Humphreys, Carine Bonnard, Juni Palmgren, Yuqing Li, Yi Li, Kee S Chia, Edison T Liu, Per Hall, Jianjun Liu, Sara Wedrén Breast Cancer Research 2006, 8:R67 (28 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

158.

Review   Open Access

Alkaline fluid circulation in ultramafic rocks and formation of nucleotide constituents: a hypothesis

Nils G Holm, Marion Dumont, Magnus Ivarsson, Cécile Konn Geochemical Transactions 2006, 7:7 (25 July 2006)

Abstract | Full text | PDF | PubMed

159.

Methodology article   Open Access

Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps

Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Robert M MacCallum BMC Bioinformatics 2006, 7:357 (25 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

160.

Research   Open Access Highly Accessed

What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?

Diana Ekman, Sara Light, Åsa K Björklund, Arne Elofsson Genome Biology 2006, 7:R45 (16 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An analysis of hubs (proteins with many interactors) and non-hubs in the S. cerevisiae protein interaction network shows that hub proteins are enriched with multiple and repeated domains.

161.

Methodology   Open Access

Advantages of doubly polished thin sections for the study of microfossils in volcanic rock

M Ivarsson Geochemical Transactions 2006, 7:5 (30 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Doubly polished thin sections, originally prepared for fluid inclusion studies, present great advantages in the study of microfossils in volcanic rocks. Better visibility and light conditions, variation in thickness of the thin sections and the possibility to combine fluid inclusion studies with microfossil studies lead to a wide range of advantages over ordinary thin sections.

162.

Research   Open Access

Analysing ethnobotanical and fishery-related importance of mangroves of the East-Godavari Delta (Andhra Pradesh, India) for conservation and management purposes

F Dahdouh-Guebas, S Collin, D Lo Seen, P Rönnbäck, D Depommier, T Ravishankar, N Koedam Journal of Ethnobiology and Ethnomedicine 2006, 2:24 (8 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

163.

Database   Open Access

NovelFam3000 – Uncharacterized human protein domains conserved across model organisms

Danielle Kemmer, Raf M Podowski, David Arenillas, Jonathan Lim, Emily Hodges, Peggy Roth, Erik LL Sonnhammer, Christer Höög, Wyeth W Wasserman BMC Genomics 2006, 7:48 (13 March 2006)

Abstract | Full text | PDF | PubMed

164.

Methodology article   Open Access

Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional normalization method

Henrik Bengtsson, Ola Hössjer BMC Bioinformatics 2006, 7:100 (1 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

165.

Methodology article   Open Access

Automatic discovery of cross-family sequence features associated with protein function

Markus Brameier, Josien Haan, Andrea Krings , Robert M MacCallum BMC Bioinformatics 2006, 7:16 (12 January 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

166.

Research article   Open Access

ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related proteins

Tomas Ohlson, Arne Elofsson BMC Bioinformatics 2005, 6:253 (14 October 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

167.

Research article   Open Access

Analysis of Escherichia coli nicotinate mononucleotide adenylyltransferase mutants in vivo and in vitro

Martin Stancek, Robert Schnell, Monica Rydén-Aulin BMC Biochemistry 2005, 6:16 (9 September 2005)

Abstract | Full text | PDF | PubMed

168.

Research   Open Access

A retrospective study of PBDEs and PCBs in human milk from the Faroe Islands

Britta Fängström, Anna Strid, Philippe Grandjean, Pál Weihe, Åke Bergman Environmental Health: A Global Access Science Source 2005, 4:12 (14 July 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

169.

Meeting abstract   Open Access

Lowered stomata conductance promotes the oxidative burst, an essential factor in the promotion of programmed cell death

Per Mühlenbock, Stanislaw Karpinski BMC Plant Biology 2005, 5(Suppl 1):S24 (31 May 2005)

Full text | PDF

170.

Research article   Open Access

A combined approach exploring gene function based on Worm-Human Orthology

Ivica Tamas, Emily Hodges, Patrick Dessi, Robert Johnsen, Ana Vaz Gomes BMC Genomics 2005, 6:65 (6 May 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

171.

Research article   Open Access

Negative density-distribution relationship in butterflies

Jussi Päivinen, Alessandro Grapputo, Veijo Kaitala, Atte Komonen, Janne S Kotiaho, Kimmo Saarinen, Niklas Wahlberg BMC Biology 2005, 3:5 (1 March 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A strong negative relationship exists between density and distribution in Finnish butterflies, an unexpected finding which may be due to the isolation of suitable habitat patches on the edge of the butterfly distribution range.

172.

Research article   Open Access Highly Accessed

General practitioners' reasoning when considering the diagnosis heart failure: a think-aloud study

Ylva Skånér, Lars Backlund, Henry Montgomery, Johan Bring, Lars-Erik Strender BMC Family Practice 2005, 6:4 (15 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

173.

Research article   Open Access

GPs' decisions on drug treatment for patients with high cholesterol values: A think-aloud study

Lars Backlund, Ylva Skånér, Henry Montgomery, Johan Bring, Lars-Erik Strender BMC Medical Informatics and Decision Making 2004, 4:23 (13 December 2004)

Abstract | Full text | PDF | PubMed

174.

Research article   Open Access

The role of guidelines and the patient's life-style in GPs' management of hypercholesterolaemia

Lars Backlund, Ylva Skånér, Henry Montgomery, Johan Bring, Lars-Erik Strender BMC Family Practice 2004, 5:3 (9 March 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

These case vignettes reveal the logic in GP's departures from guidelines in treatment of hypercholesterolaemia, and suggest that guidelines need more, not less, detail.

175.

Research article   Open Access Highly Accessed

Network analysis of metabolic enzyme evolution in Escherichia coli

Sara Light, Per Kraulis BMC Bioinformatics 2004, 5:15 (18 February 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Network analysis of metabolic enzymes in Escherichia coli indicates that that the patchwork evolution model, by which functional specialization follows gene duplication, is the main method of metabolic enzyme evolution.

176.

Research article   Open Access

Decreased inducibility of TNF expression in lipid-loaded macrophages

Mikko PS Ares, Maria Stollenwerk, Anneli Olsson, Bengt Kallin, Stefan Jovinge, Jan Nilsson BMC Immunology 2002, 3:13 (6 October 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

177.

Research article   Open Access Highly Accessed

Prediction of MHC class I binding peptides, using SVMHC

Pierre Dönnes, Arne Elofsson BMC Bioinformatics 2002, 3:25 (11 September 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

178.

Meeting report   Free

The salmon genome (and other issues in bioinformatics)

Lena EF Milchert, David A Liberles, Arne Elofsson Genome Biology 2002, 3:reports4022-reports4022.4 (24 June 2002)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A report on the fourth annual conference of the Society for Bioinformatics in the Nordic Countries (SOCBIN), Bioinformatics 2002, Bergen, Norway, 4-7 April 2002.

179.

Meeting report   Free

Evolution enters the genomic era

David A Liberles Genome Biology 2001, 2:reports4026-reports4026.5 (12 October 2001)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A report on the 18th Congress of the European Society for Evolutionary Biology (ESEB), Aarhus, Denmark, 20-25 August, 2001.

180.

Research article   Open Access

A study of quality measures for protein threading models

Susana Cristobal, Adam Zemla, Daniel Fischer, Leszek Rychlewski, Arne Elofsson BMC Bioinformatics 2001, 2:5 (1 August 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

181.

Research   Open Access

The Adaptive Evolution Database (TAED)

David A Liberles, David R Schreiber, Sridhar Govindarajan, Stephen G Chamberlin, Steven A Benner Genome Biology 2001, 2:research0028-research0028.6 (24 July 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In the Adaptive Evolution Database (TAED), potential examples of positive adaptation are identified by high values for the normalized ratio of nonsynonymous to synonymous nucleotide substitution rates (KA/KS values). Evolutionary trees and reconstructed ancestral sequences were extracted from the Master Catalog for every subtree containing proteins from the Chordata only or the Embryophyta only. An unexpectedly large number of families were found to have at least one branch with high KA/KS values. TAED is a raw resource for bioinformaticists interested in data mining and for experimental evolutionists seeking candidate examples of adaptive evolution for further experimental study.

182.

Deposited research article   Free

The Adaptive Evolution Database (TAED)

David A Liberles, David R Schreiber, Sridhar Govindarajan, Stephen G Chamberlin, Steven A Benner Genome Biology 2001, 2:preprint0003-preprint0003.18 (9 March 2001)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The ratio of nonsynonymous to synonymous nucleotide substitution (Ka/Ks) has been estimated for each branch in the evolutionary trees of chordates and green plants. Branches with high Ka/Ks values represent candidate episodes where the protein may have undergone positive selection; these branches have been collected into a database called The Adaptive Evolution Database (TAED).

183.

Research article   Open Access

Different conformations of nascent polypeptides during translocation across the ER membrane

Ismael Mingarro, IngMarie Nilsson, Paul Whitley, Gunnar von Heijne BMC Cell Biology 2000, 1:3 (19 December 2000)

Abstract | Full text | PDF | PubMed

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