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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Fox Chase Cancer Center

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26.

Research article   Open Access Highly Accessed

Circulating tumor cells as prognostic and predictive markers in metastatic breast cancer patients receiving first-line systemic treatment

Mario Giuliano, Antonio Giordano, Summer Jackson, Kenneth R Hess, Ugo De Giorgi, Michal Mego, Beverly C Handy, Naoto T Ueno, Ricardo H Alvarez, Michelino De Laurentiis, Sabino De Placido, Vicente Valero, Gabriel N Hortobagyi, James M Reuben, Massimo Cristofanilli Breast Cancer Research 2011, 13:R67 (15 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

Research article   Open Access Highly Accessed

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

Hyung-Ok Lee, Stefanie R Mullins, Janusz Franco-Barraza, Matthildi Valianou, Edna Cukierman, Jonathan D Cheng BMC Cancer 2011, 11:245 (13 June 2011)

Abstract | Full text | PDF | PubMed

28.

Research article   Open Access

Exploring the symbiotic pangenome of the nitrogen-fixing bacterium Sinorhizobium meliloti

Marco Galardini, Alessio Mengoni, Matteo Brilli, Francesco Pini, Antonella Fioravanti, Susan Lucas, Alla Lapidus, Jan-Fang Cheng, Lynne Goodwin, Samuel Pitluck, Miriam Land, Loren Hauser, Tanja Woyke, Natalia Mikhailova, Natalia Ivanova, Hajnalka Daligault, David Bruce, Chris Detter, Roxanne Tapia, Cliff Han, Hazuki Teshima, Stefano Mocali, Marco Bazzicalupo, Emanuele G Biondi BMC Genomics 2011, 12:235 (12 May 2011)

Abstract | Full text | PDF | PubMed

29.

Minireview   Open Access Highly Accessed

Circulating tumor cells in breast cancer: A tool whose time has come of age

Ramona F Swaby, Massimo Cristofanilli BMC Medicine 2011, 9:43 (21 April 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Swaby and Cristofanilli review circulating tumor cells (CTCs), which are isolated tumor cells that have disseminated from the site of disease, in terms of clinical utility in targeted therapy, response to treatment and prognosis.

30.

Research article   Open Access Highly Accessed

Exploring the link between MORF4L1 and risk of breast cancer

Griselda Martrat, Christopher A Maxwell, Emiko Tominaga, Montserrat Porta-de-la-Riva, Núria Bonifaci, Laia Gómez-Baldó, Massimo Bogliolo, Conxi Lázaro, Ignacio Blanco, Joan Brunet, Helena Aguilar, Juana Fernández-Rodríguez, Sheila Seal, Anthony Renwick, Nazneen Rahman, Julia Kühl, Kornelia Neveling, Detlev Schindler, María J Ramírez, María Castellà, Gonzalo Hernández, Douglas F Easton, Susan Peock, Margaret Cook, Clare T Oliver, Debra Frost, Radka Platte, D Gareth Evans, Fiona Lalloo et al. Breast Cancer Research 2011, 13:R40 (5 April 2011)

Abstract | Full text | PDF | PubMed

31.

Research   Open Access

In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2

Klara Berencsi, Pyapalli Rani, Tianqian Zhang, Laura Gross, Michael Mastrangelo, Neal J Meropol, Dorothee Herlyn, Rajasekharan Somasundaram Journal of Translational Medicine 2011, 9:33 (30 March 2011)

Abstract | Full text | PDF | PubMed

32.

Research article   Open Access

Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer

Callinice D Capo-chichi, Kathy Q Cai, Fiona Simpkins, Parvin Ganjei-Azar, Andrew K Godwin, Xiang-Xi Xu BMC Medicine 2011, 9:28 (26 March 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Defects in nuclear morphology and ploidy, two of the hallmarks of ovarian cancer, may be caused by aberrant nuclear envelope protein lamin A/C expression, which may also cause similar defects in other cancer types.

33.

Research article   Open Access Highly Accessed

Sun protection and sunbathing practices among at-risk family members of patients with melanoma

Sharon L Manne, Elliot J Coups, Paul B Jacobsen, Michael Ming, Carolyn J Heckman, Stuart Lessin BMC Public Health 2011, 11:122 (21 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The level of sunbathing and sun protection practices varies among first-degree relatives of patients with melanoma, with older and more educated relatives showing a lower perception of the benefits of sunbathing and a higher knowledge of sun protection norms.

34.

Research article   Open Access

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry

Letitia D Smith, Andrea A Tesoriero, Ee M Wong, Susan J Ramus, Frances P O'Malley, Anna Marie Mulligan, Mary Beth Terry, Ruby T Senie, Regina M Santella, Esther M John, Irene L Andrulis, Hilmi Ozcelik, Mary B Daly, Andrew K Godwin, Saundra S Buys, Stephen Fox, David E Goldgar, Graham G Giles, John L Hopper, Melissa C Southey Breast Cancer Research 2011, 13:R14 (31 January 2011)

Abstract | Full text | PDF | PubMed

35.

Research   Open Access

In utero exposure to butyl benzyl phthalate induces modifications in the morphology and the gene expression profile of the mammary gland: an experimental study in rats

Raquel Moral, Julia Santucci-Pereira, Richard Wang, Irma H Russo, Coral A Lamartiniere, Jose Russo Environmental Health 2011, 10:5 (17 January 2011)

Abstract | Full text | PDF | PubMed | F1000 Medicine | F1000 Biology

36.

Research   Open Access Highly Accessed

Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin

Arti Shukla, Jedd M Hillegass, Maximilian B MacPherson, Stacie L Beuschel, Pamela M Vacek, Harvey I Pass, Michele Carbone, Joseph R Testa, Brooke T Mossman Molecular Cancer 2010, 9:314 (15 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

Research article   Open Access Highly Accessed

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

Logan C Walker, Zachary S Fredericksen, Xianshu Wang, Robert Tarrell, Vernon S Pankratz, Noralane M Lindor, Jonathan Beesley, Sue Healey, Xiaoqing Chen, Dominique Stoppa-Lyonnet, Carole Tirapo, Sophie Giraud, Sylvie Mazoyer, Danièle Muller, Jean-Pierre Fricker, Capucine Delnatte, Rita K Schmutzler, Barbara Wappenschmidt, Christoph Engel, Ines Schönbuchner, Helmut Deissler, Alfons Meindl, Frans B Hogervorst, Martijn Verheus, Maartje J Hooning, Ans MW van den Ouweland, Marcel R Nelen, Margreet GEM Ausems et al. Breast Cancer Research 2010, 12:R102 (29 November 2010)

Abstract | Full text | PDF | PubMed

38.

Research article   Open Access Highly Accessed

Prospective case-control study of premenopausal serum estradiol and testosterone levels and breast cancer risk

Joanne F Dorgan, Frank Z Stanczyk, Lisa L Kahle, Louise A Brinton Breast Cancer Research 2010, 12:R98 (18 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

Research article   Open Access Highly Accessed

Modifiers of notch transcriptional activity identified by genome-wide RNAi

Philippos Mourikis, Robert J Lake, Christopher B Firnhaber, Brian S DeDecker BMC Developmental Biology 2010, 10:107 (19 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

40.

Research   Open Access

Development of a syngeneic mouse model of epithelial ovarian cancer

Bridget A Quinn, Fang Xiao, Laura Bickel, Lainie Martin, Xiang Hua, Andres Klein-Szanto, Denise C Connolly Journal of Ovarian Research 2010, 3:24 (19 October 2010)

Abstract | Full text | PDF | PubMed

41.

Research   Open Access

The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation

Finola E Moore, Evan C Osmundson, Jennifer Koblinski, Elena Pugacheva, Erica A Golemis, Dipankar Ray, Hiroaki Kiyokawa Cell Division 2010, 5:22 (8 September 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The regulatory factor, Smurf2, controls cell cycle progression by direct physical effect upon the stability and ubiquitination of the NEDD9 protein, which in turn regulates timely entry into mitosis.

42.

Research   Open Access

I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

Ayad Al-Katib, Alan A Arnold, Amro Aboukameel, Angela Sosin, Peter Smith, Anwar N Mohamed, Frances W Beck, Ramzi M Mohammad Molecular Cancer 2010, 9:228 (1 September 2010)

Abstract | Full text | PDF | PubMed

43.

Research   Open Access

Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

Konstantin Golovine, Peter Makhov, Robert G Uzzo, Alexander Kutikov, David J Kaplan, Eric Fox, Vladimir M Kolenko Molecular Cancer 2010, 9:183 (9 July 2010)

Abstract | Full text | PDF | PubMed

44.

Research   Open Access Highly Accessed

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

Alyssa L Kennedy, Tony McBryan, Greg H Enders, F Johnson, Rugang Zhang, Peter D Adams Cell Division 2010, 5:16 (22 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

Commentary   Open Access

Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry

Greg H Enders Cell Division 2010, 5:12 (13 May 2010)

Abstract | Full text | PDF | PubMed

46.

Research   Open Access

Over-expression of eukaryotic translation initiation factor 4 gamma 1 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma

Luxia Tu, Zhen Liu, Xiufang He, Ying He, Huiling Yang, Qingping Jiang, Siming Xie, Guanghui Xiao, Xin Li, Kaitai Yao, Weiyi Fang Molecular Cancer 2010, 9:78 (16 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

Review   Open Access Highly Accessed

Vascular clamping in liver surgery: physiology, indications and techniques

Elie K Chouillard, Andrew A Gumbs, Daniel Cherqui Annals of Surgical Innovation and Research 2010, 4:2 (26 March 2010)

Abstract | Full text | PDF | PubMed

48.

Research article   Open Access

A comparison of perioperative outcomes of Video-Assisted Thoracic Surgical (VATS) Lobectomy with open thoracotomy and lobectomy: Results of an analysis using propensity score based weighting

Walter J Scott, Ronald S Matteotti, Brian L Egleston, Salewa Oseni, James F Flaherty Annals of Surgical Innovation and Research 2010, 4:1 (22 March 2010)

Abstract | Full text | PDF | PubMed

49.

Research article   Open Access

Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila

Silvia Gluderer, Erich Brunner, Markus Germann, Virginija Jovaisaite, Changqing Li, Cyrill A Rentsch, Ernst Hafen, Hugo Stocker Journal of Biology 2010, 9:9 (11 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Stocker and colleagues identify and analyze a growth-promoting complex in Drosophila, formed between the putative transcription factor BunA, for which human homologs can functionally substitute, and the adaptor protein Madm.

50.

Research article   Open Access Highly Accessed

Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent

Deborah A Altomare, Susanna M Rybak, Jianming Pei, Jacob V Maizel, Mitchell Cheung, Joseph R Testa, Kuslima Shogen BMC Cancer 2010, 10:34 (5 February 2010)

Abstract | Full text | PDF | PubMed

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