Genomic analysis of Xenopus organizer function
BMC Developmental Biology 2006, 6:27 (6 June 2006)
Simulation of the Xenopus organizer function by inhibiting BMP and Wnt pathways, through overexpression of Noggin and Dkk-1, demonstrates that BMP induction of genes occurs in early development for dorsal patterning and Wnt acts later.
Insights into the structure and activity of prototype foamy virus RNase H
Retrovirology 2012, 9:14 (10 February 2012)
This paper demonstrates that the independent PFV RNase H domain is structured and active. The presence of the C-helix in PFV RNase H could be confirmed by assigning the protein backbone and calculating the chemical shift index using NMR spectroscopy.
Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure
BMC Structural Biology 2013, 13:17 (2 October 2013)
Mining the literature: new methods to exploit keyword profiles
Genome Medicine 2012, 4:81 (30 October 2012)
Miguel Andrade-Navarro highlights two recent publications by Wasserman et al. demonstrating that keyword profiles can be used to detect new associations between genes and inherited diseases.
Differential RelA- and RelB-dependent gene transcription in LT βR-stimulated mouse embryonic fibroblasts
BMC Genomics 2008, 9:606 (16 December 2008)
Preimplantation development regulatory pathway construction through a text-mining approach
BMC Genomics 2011, 12(Suppl 4):S3 (22 December 2011)
Distribution of DNA replication proteins in Drosophila cells
BMC Cell Biology 2007, 8:42 (15 October 2007)
Whilst the DNA replication machinery in Drosophila is organized into replication foci similar to most higher eukaryotes, surprisingly no accumulation of replication factors could be detected, suggesting a fundamental difference between Drosophila and mammalian cells.
Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent
Arthritis Research & Therapy 2009, 11:R16 (5 February 2009)
Recent developments in StemBase: a tool to study gene expression in human and murine stem cells
BMC Research Notes 2009, 2:39 (10 March 2009)
StemBase, the comprehensive online repository developed by the Canadian Stem Cell Network, now supports the analysis of gene coexpression patterns in human and mouse stem cells, and the visualization of expression data by genomic regions.
Novel insights into proteomic technologies and their clinical perspective
Genome Med 2009, 1:53 (21 May 2009)
A report on the Proteomic Forum 2009 conference, Berlin, Germany, 29 March to 2 April, 2009.
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)
BMC Structural Biology 2005, 5:21 (14 December 2005)
Multi-compartmental modeling of SORLA’s influence on amyloidogenic processing in Alzheimer’s disease
BMC Systems Biology 2012, 6:74 (22 June 2012)
Genomic parasites and genome evolution
Genome Biology 2009, 10:306 (15 April 2009)
A report of the Second International Conference/Workshop on the Genomic Impact of Eukaryotic Transposable Elements, Pacific Grove, USA, 6-10 February 2009.
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming
BMC Developmental Biology 2005, 5:18 (24 August 2005)
The short form of Dnmt1, the prevalent maintenance DNA methylase of mouse preimplantation embryos, is specifically immobilized in the cytoplasm, which may be a factor in epigenetic reprogamming during this stage of development.
Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression
BMC Genomics 2006, 7:148 (13 June 2006)
Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis
BMC Medical Genetics 2012, 13:8 (27 January 2012)
Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina
BMC Developmental Biology 2009, 9:40 (8 July 2009)
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process
BMC Bioinformatics 2005, 6:285 (30 November 2005)
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker
BMC Cancer 2005, 5:47 (17 May 2005)
QiSampler: evaluation of scoring schemes for high-throughput datasets using a repetitive sampling strategy on gold standards
BMC Research Notes 2011, 4:57 (9 March 2011)
Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis
BMC Cancer 2005, 5:5 (14 January 2005)
Ca 2+ binding to complement-type repeat domains 5 and 6 from the low-density lipoprotein receptor-related protein
BMC Biochemistry 2003, 4:7 (18 August 2003)
Pseudogenes as an alternative source of natural antisense transcripts
BMC Evolutionary Biology 2010, 10:338 (3 November 2010)
Receptor guanylyl cyclase B-mediated cGMP signalling controls axon bifurcation of cranial sensory ganglion neurons at the embryonic hindbrain
BMC Pharmacology and Toxicology 2013, 14(Suppl 1):P71 (29 August 2013)
Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy
BMC Cancer 2006, 6:124 (10 May 2006)