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1.

Method   Open Access Highly Accessed

Bioconductor: open software development for computational biology and bioinformatics

Robert C Gentleman, Vincent J Carey, Douglas M Bates, Ben Bolstad, Marcel Dettling, Sandrine Dudoit, Byron Ellis, Laurent Gautier, Yongchao Ge, Jeff Gentry, Kurt Hornik, Torsten Hothorn, Wolfgang Huber, Stefano Iacus, Rafael Irizarry, Friedrich Leisch, Cheng Li, Martin Maechler, Anthony J Rossini, Gunther Sawitzki, Colin Smith, Gordon Smyth, Luke Tierney, Jean YH Yang, Jianhua Zhang Genome Biology 2004, 5:R80 (15 September 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A detailed description of the aims and methods of the Bioconductor project, an initiative for the collaborative creation of extensible software for computational biology and bioinformatics.

2.

Forum   Open Access Highly Accessed

What does the concept of the stem cell niche really mean today?

Arthur D Lander, Judith Kimble, Hans Clevers, Elaine Fuchs, Didier Montarras, Margaret Buckingham, Anne L Calof, Andreas Trumpp, Thordur Oskarsson BMC Biology 2012, 10:19 (9 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

How do current researchers view the stem cell niche? Eight experts from different fields provide their perspective, and ask how stem cells evolve in such an environment, launching a new Forum article type within the cross-journal collection on stem cells.

3.

Research article   Open Access Highly Accessed

Coffee consumption modifies risk of estrogen-receptor negative breast cancer

Jingmei Li, Petra Seibold, Jenny Chang-Claude, Dieter Flesch-Janys, Jianjun Liu, Kamila Czene, Keith Humphreys, Per Hall Breast Cancer Research 2011, 13:R49 (14 May 2011)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

A Swedish study finds that a high daily intake of coffee is associated with a statistically significant decrease in estrogen receptor-negative breast cancer among postmenopausal women.

4.

Research highlight   Subscription Highly Accessed

The aging epigenome: DNA methylation from the cradle to the grave

Marc Winnefeld, Frank Lyko Genome Biology 2012, 13:165 (30 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Frank Lyko and Marc Winnefeld highlight a new survey of age-related epigenetic changes in newborn and centenarian methylomes

5.

Research article   Open Access Highly Accessed

The Drosophila methyl-DNA binding protein MBD2/3 interacts with the NuRD complex via p55 and MI-2

Joachim Marhold, Alexander Brehm, Katja Kramer BMC Molecular Biology 2004, 5:20 (29 October 2004)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access Highly Accessed

Serum microRNAs as non-invasive biomarkers for cancer

Jan C Brase, Daniela Wuttig, Ruprecht Kuner, Holger Sültmann Molecular Cancer 2010, 9:306 (26 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

Research article   Open Access Highly Accessed

Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3

Ramona Schmid, Patrick Baum, Carina Ittrich, Katrin Fundel-Clemens, Wolfgang Huber, Benedikt Brors, Roland Eils, Andreas Weith, Detlev Mennerich, Karsten Quast BMC Genomics 2010, 11:349 (2 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

Methodology article   Open Access

Conditional gene expression systems in the transgenic rat brain

Kai Schönig, Tillmann Weber, Ariana Frömmig, Lena Wendler, Brigitte Pesold, Dominik Djandji, Hermann Bujard, Dusan Bartsch BMC Biology 2012, 10:77 (3 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The advantages of rats over mice for biomedical research have to date been offset by a dearth of proven methods for their genetic manipulation. Addressing this deficit, Bartsch and coauthors develop transgenic rats with inducible reporter gene expression in forebrain neurons.

9.

Research   Open Access Highly Accessed

The head-regeneration transcriptome of the planarian Schmidtea mediterranea

Thomas Sandmann, Matthias C Vogg, Suthira Owlarn, Michael Boutros, Kerstin Bartscherer Genome Biology 2011, 12:R76 (16 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Next generation sequencing was used to investigate the transcriptome of head regeneration in the planarian Schmidtea mediterranea

10.

Research article   Open Access Highly Accessed

Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

Methodology   Open Access

RNAi-based validation of antibodies for reverse phase protein arrays

Heiko A Mannsperger, Stefan Uhlmann, Christian Schmidt, Stefan Wiemann, Özgür Sahin, Ulrike Korf Proteome Science 2010, 8:69 (23 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

Research   Open Access Highly Accessed

Body fluid derived exosomes as a novel template for clinical diagnostics

Sascha Keller, Johannes Ridinger, Anne-Kathleen Rupp, Johannes WG Janssen, Peter Altevogt Journal of Translational Medicine 2011, 9:86 (8 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

Methodology   Open Access

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

Jan C Brase, Heiko Mannsperger, Holger Fröhlich, Stephan Gade, Christian Schmidt, Stefan Wiemann, Tim Beissbarth, Thorsten Schlomm, Holger Sültmann, Ulrike Korf Proteome Science 2010, 8:36 (22 June 2010)

Abstract | Full text | PDF | PubMed

14.

Methodology article   Open Access Highly Accessed

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

Phillip Hundeshagen, Anne Hamacher-Brady, Roland Eils, Nathan R Brady BMC Biology 2011, 9:38 (2 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

There is much interest in activating autophagy, by which cells deliver their own contents to the lysosomal system, in cancer therapy. Nathan Brady and colleagues report a flow cytometric method whereby drug candidates may be screened for effects on separate steps in the process.

15.

Review   Open Access Highly Accessed

The receptor RAGE: Bridging inflammation and cancer

Astrid Riehl, Julia Németh, Peter Angel, Jochen Hess Cell Communication and Signaling 2009, 7:12 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

Research article   Open Access

Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study

Rebecca Ritte, Annekatrin Lukanova, Franco Berrino, Laure Dossus, Anne Tjønneland, Anja Olsen, Thure Overvad, Kim Overvad, Françoise Clavel-Chapelon, Agnès Fournier, Guy Fagherazzi, Sabine Rohrmann, Birgit Teucher, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, Salvatore Panico, Rosario Tumino, Paolo Vineis, José Quirós, Genevieve Buckland, Maria-José Sánchez, Pilar Amiano, María-Dolores Chirlaque, Eva Ardanaz, Malin Sund et al. Breast Cancer Research 2012, 14:R76 (14 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Review   Open Access Highly Accessed

Molecular biology of cantharidin in cancer cells

Rolf Rauh, Stefan Kahl, Herbert Boechzelt, Rudolf Bauer, Bernd Kaina, Thomas Efferth Chinese Medicine 2007, 2:8 (4 July 2007)

Abstract | Full text | PDF | PubMed

18.

Research article   Open Access Highly Accessed

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Anna Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas vO Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio, Iván Muñoz-Repeto, Mercedes Durán, Javier Godino, Maroulio Pertesi, Javier Benítez, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Elisa Cattaneo et al. Breast Cancer Research 2011, 13:R110 (2 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

Research article   Open Access Highly Accessed

Exploring the link between MORF4L1 and risk of breast cancer

Griselda Martrat, Christopher A Maxwell, Emiko Tominaga, Montserrat Porta-de-la-Riva, Núria Bonifaci, Laia Gómez-Baldó, Massimo Bogliolo, Conxi Lázaro, Ignacio Blanco, Joan Brunet, Helena Aguilar, Juana Fernández-Rodríguez, Sheila Seal, Anthony Renwick, Nazneen Rahman, Julia Kühl, Kornelia Neveling, Detlev Schindler, María J Ramírez, María Castellà, Gonzalo Hernández, Douglas F Easton, Susan Peock, Margaret Cook, Clare T Oliver, Debra Frost, Radka Platte, D Gareth Evans, Fiona Lalloo et al. Breast Cancer Research 2011, 13:R40 (5 April 2011)

Abstract | Full text | PDF | PubMed

20.

Short paper   Open Access Highly Accessed

DNA-vaccination via tattooing induces stronger humoral and cellular immune responses than intramuscular delivery supported by molecular adjuvants

Dana Pokorna, Ivonne Rubio, Martin Müller Genetic Vaccines and Therapy 2008, 6:4 (7 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The tattoo delivery of DNA vaccines is cost effective, induces a greater immune response, and is a more efficient delivery strategy for laboratory studies than intramuscular injection.

21.

Research article   Open Access

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Antonis C Antoniou, Karoline B Kuchenbaecker, Penny Soucy, Jonathan Beesley, Xiaoqing Chen, Lesley McGuffog, Andrew Lee, Daniel Barrowdale, Sue Healey, Olga M Sinilnikova, Maria A Caligo, Niklas Loman, Katja Harbst, Annika Lindblom, Brita Arver, Richard Rosenquist, Per Karlsson, Kate Nathanson, Susan Domchek, Tim Rebbeck, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Elżbieta Złowowcka-Perłowska, Ana Osorio, Mercedes Durán, Raquel Andrés, Javier Benítez, Ute Hamann et al. Breast Cancer Research 2012, 14:R33 (20 February 2012)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access Highly Accessed

Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

Laura D Nelson, Christian Bender, Heiko Mannsperger, Daniel Buergy, Patryk Kambakamba, Giridhar Mudduluru, Ulrike Korf, Dennis Hughes, Michael W Van Dyke, Heike Allgayer Molecular Cancer 2012, 11:38 (8 June 2012)

Abstract | Full text | PDF | PubMed

23.

Question and Answer   Open Access

Video Q&A: Excess body weight and cancer

Rudolf Kaaks BMC Medicine 2013, 11:2 (3 January 2013)

Full text | PDF | PubMed |  Editor’s summary

Rudolf Kaaks talks about types of cancers linked to the overweight and obesity epidemic, and advises that although weight loss may decrease the risk of developing cancer, ultimately prevention is better than the cure.

24.

Research   Open Access

Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress

Simon M Dittami, Delphine Scornet, Jean-Louis Petit, Béatrice Ségurens, Corinne Da Silva, Erwan Corre, Michael Dondrup, Karl-Heinz Glatting, Rainer König, Lieven Sterck, Pierre Rouzé, Yves Van de Peer, J Mark Cock, Catherine Boyen, Thierry Tonon Genome Biology 2009, 10:R66 (16 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The brown alga Ectocarpus siliculosus, unlike terrestrial plants, undergoes extensive reprogramming of its transcriptome during the acclimation to mild abiotic stress.

25.

Research article   Open Access Highly Accessed

Serum 25-hydroxyvitamin D and postmenopausal breast cancer survival: a prospective patient cohort study

Alina Vrieling, Rebecca Hein, Sascha Abbas, Andreas Schneeweiss, Dieter Flesch-Janys, Jenny Chang-Claude Breast Cancer Research 2011, 13:R74 (26 July 2011)

Abstract | Full text | PDF | PubMed

26.

Research   Open Access

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

Frank Westermann, Daniel Muth, Axel Benner, Tobias Bauer, Kai-Oliver Henrich, André Oberthuer, Benedikt Brors, Tim Beissbarth, Jo Vandesompele, Filip Pattyn, Barbara Hero, Rainer König, Matthias Fischer, Manfred Schwab Genome Biology 2008, 9:R150 (13 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Differences in MYCN/c-MYC target gene expression are associated with distinct neuroblastoma subtypes and clinical outcome.

27.

Software   Open Access Highly Accessed

Analysis of cell-based RNAi screens

Michael Boutros, Lígia P Brás, Wolfgang Huber Genome Biology 2006, 7:R66 (25 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

cellHTS is a new method for the analysis and documentation of RNAi screens.

28.

Primary research   Open Access Highly Accessed

MHC class I-related chain A and B ligands are differentially expressed in human cervical cancer cell lines

Susana del Toro-Arreola, Naela Arreygue-Garcia, Adriana Aguilar-Lemarroy, Angel Cid-Arregui, Miriam Jimenez-Perez, Jesse Haramati, Patricio Barros-Nuñez, Oscar Gonzalez-Ramella, Alicia del Toro-Arreola, Pablo Ortiz-Lazareno, Georgina Hernandez-Flores, Alejandro Bravo-Cuellar, Adrian Daneri-Navarro, Luis F Jave-Suarez Cancer Cell International 2011, 11:15 (1 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

Research article   Open Access Highly Accessed

Off-target effects of siRNA specific for GFP

Cordula Tschuch, Angela Schulz, Armin Pscherer, Wiebke Werft, Axel Benner, Agnes Hotz-Wagenblatt, Leticia Barrionuevo, Peter Lichter, Daniel Mertens BMC Molecular Biology 2008, 9:60 (24 June 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

30.

Research   Open Access

Assisted reproductive techniques and the risk of anorectal malformations: a German case-control study

Nadine Zwink, Ekkehart Jenetzky, Eberhard Schmiedeke, Dominik Schmidt, Stefanie Märzheuser, Sabine Grasshoff-Derr, Stefan Holland-Cunz, Sandra Weih, Stuart Hosie, Peter Reifferscheid, Helen Ameis, Christina Kujath, Anke Rißmann, Florian Obermayr, Nicole Schwarzer, Enrika Bartels, Heiko Reutter, Hermann Brenner, Orphanet Journal of Rare Diseases 2012, 7:65 (15 September 2012)

Abstract | Full text | PDF | PubMed

31.

Review   Open Access

Epstein-Barr virus genetics: talking about the BAC generation

Regina Feederle, Emmalene J Bartlett, Henri-Jacques Delecluse Herpesviridae 2010, 1:6 (7 December 2010)

Abstract | Full text | PDF | PubMed

32.

Study protocol   Open Access Highly Accessed

Treatment of patients with atypical meningiomas Simpson grade 4 and 5 with a carbon ion boost in combination with postoperative photon radiotherapy: The MARCIE Trial

Stephanie E Combs, Lutz Edler, Iris Burkholder, Stefan Rieken, Daniel Habermehl, Oliver Jäkel, Thomas Haberer, Andreas Unterberg, Wolfgang Wick, Jürgen Debus, Renate Haselmann BMC Cancer 2010, 10:615 (9 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

Research article   Open Access Highly Accessed

Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia

Evgeny A Moskalev, Katrin Luckert, Ivan A Vorobjev, Sergey E Mastitsky, Aleena A Gladkikh, Achim Stephan, Marita Schrenk, Kamil D Kaplanov, Olga B Kalashnikova, Oliver Pötz, Thomas O Joos, Jörg D Hoheisel BMC Cancer 2012, 12:213 (6 June 2012)

Abstract | Full text | PDF | PubMed

34.

Research article   Open Access Highly Accessed

Integrative analysis of RUNX1 downstream pathways and target genes

Joëlle Michaud, Ken M Simpson, Robert Escher, Karine Buchet-Poyau, Tim Beissbarth, Catherine Carmichael, Matthew E Ritchie, Frédéric Schütz, Ping Cannon, Marjorie Liu, Xiaofeng Shen, Yoshiaki Ito, Wendy H Raskind, Marshall S Horwitz, Motomi Osato, David R Turner, Terence P Speed, Maria Kavallaris, Gordon K Smyth, Hamish S Scott BMC Genomics 2008, 9:363 (31 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

Research   Open Access Highly Accessed

Functions, structure, and read-through alternative splicing of feline APOBEC3 genes

Carsten Münk, Thomas Beck, Jörg Zielonka, Agnes Hotz-Wagenblatt, Sarah Chareza, Marion Battenberg, Jens Thielebein, Klaus Cichutek, Ignacio G Bravo, Stephen J O'Brien, Martin Lochelt, Naoya Yuhki Genome Biology 2008, 9:R48 (3 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

APOBEC3 (A3, Apolipoprotein B mRNA-editing catalytic polypeptide 3) genes in the genome of domestic cat (Felis catus) were identified and characterized

36.

Research article   Open Access Highly Accessed

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

Roger L Milne, Mia M Gaudet, Amanda B Spurdle, Peter A Fasching, Fergus J Couch, Javier Benítez, José Ignacio Arias Pérez, M Pilar Zamora, Núria Malats, Isabel dos Santos Silva, Lorna J Gibson, Olivia Fletcher, Nichola Johnson, Hoda Anton-Culver, Argyrios Ziogas, Jonine Figueroa, Louise Brinton, Mark E Sherman, Jolanta Lissowska, John L Hopper, Gillian S Dite, Carmel Apicella, Melissa C Southey, Alice J Sigurdson, Martha S Linet, Sara J Schonfeld, D Michal Freedman, Arto Mannermaa, Veli-Matti Kosma, Vesa Kataja et al. Breast Cancer Research 2010, 12:R110 (31 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

Research article   Open Access Highly Accessed

Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer

Dmitriy I Dovzhanskiy, Stefanie M Arnold, Thilo Hackert, Ina Oehme, Olaf Witt, Klaus Felix, Nathalia Giese, Jens Werner BMC Cancer 2012, 12:226 (8 June 2012)

Abstract | Full text | PDF | PubMed

38.

Review   Free Highly Accessed

Molecular targeted therapies for breast cancer treatment

Claus M Schlotter, Ulf Vogt, Heike Allgayer, Burkhard Brandt Breast Cancer Research 2008, 10:211 (24 July 2008)

Abstract | Full text | PDF | PubMed

39.

Software   Open Access

Design and evaluation of genome-wide libraries for RNA interference screens

Thomas Horn, Thomas Sandmann, Michael Boutros Genome Biology 2010, 11:R61 (15 June 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

NEXT-RNAi allows the design and evaluation of genome-wide RNAi screens in any organism.

40.

Study protocol   Open Access Highly Accessed

Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial

Vasileios Askoxylakis, Julien Dinkel, Monika Eichinger, Bram Stieltjes, Gregor Sommer, Ludwig G Strauss, Antonia Dimitrakopoulou-Strauss, Annette Kopp-Schneider, Uwe Haberkorn, Peter E Huber, Marc Bischof, Jürgen Debus, Christian Thieke Radiation Oncology 2012, 7:157 (14 September 2012)

Abstract | Full text | PDF | PubMed

41.

Research   Open Access Highly Accessed

MicroRNA expression after ionizing radiation in human endothelial cells

Mechthild Wagner-Ecker, Christian Schwager, Ute Wirkner, Amir Abdollahi, Peter E Huber Radiation Oncology 2010, 5:25 (26 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

Review   Open Access

Parental risk factors and anorectal malformations: systematic review and meta-analysis

Nadine Zwink, Ekkehart Jenetzky, Hermann Brenner Orphanet Journal of Rare Diseases 2011, 6:25 (17 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

43.

Original research   Open Access

A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer

Martin Schäfer, Ulrike Bauder-Wüst, Karin Leotta, Frederic Zoller, Walter Mier, Uwe Haberkorn, Michael Eisenhut, Matthias Eder EJNMMI Research 2012, 2:23 (6 June 2012)

Abstract | Full text | PDF | PubMed

44.

Research   Open Access

Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma

Kari Hemminki, Xiangdong Liu, Asta Försti, Jianguang Ji, Jan Sundquist, Kristina Sundquist Journal of Hematology & Oncology 2012, 5:59 (2 October 2012)

Abstract | Full text | PDF | PubMed

45.

Research   Open Access Highly Accessed

Intensity-modulated radiotherapy of nasopharyngeal carcinoma: a comparative treatment planning study of photons and protons

Zahra Taheri-Kadkhoda, Thomas Björk-Eriksson, Simeon Nill, Jan J Wilkens, Uwe Oelfke, Karl-Axel Johansson, Peter E Huber, Marc W Münter Radiation Oncology 2008, 3:4 (24 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

46.

Research   Open Access Highly Accessed

Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

Sung E Choe, Michael Boutros, Alan M Michelson, George M Church, Marc S Halfon Genome Biology 2005, 6:R16 (28 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

A 'spike-in' experiment for Affymetrix GeneChips is described that provides a defined dataset of 3,860 RNA species. A 'best route' combination of analysis methods is presented which allows detection of approximately 70% of true positives before reaching a 10% false discovery rate.

47.

Review   Open Access

Monitoring spindle orientation: Spindle position checkpoint in charge

Ayse K Caydasi, Bashar Ibrahim, Gislene Pereira Cell Division 2010, 5:28 (11 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

Methodology   Open Access Highly Accessed

Intensity modulated radiotherapy (IMRT) in the treatment of children and Adolescents - a single institution's experience and a review of the literature

Florian Sterzing, Eva M Stoiber, Simeon Nill, Harald Bauer, Peter Huber, Jürgen Debus, Marc W Münter Radiation Oncology 2009, 4:37 (23 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

49.

Research   Open Access Highly Accessed

Organ-, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells

Mert Erkan, Nadine Weis, Zheng Pan, Christian Schwager, Tamar Samkharadze, Xiaohua Jiang, Ute Wirkner, Nathalia A Giese, Wilhelm Ansorge, Jürgen Debus, Peter E Huber, Helmut Friess, Amir Abdollahi, Jörg Kleeff Molecular Cancer 2010, 9:88 (23 April 2010)

Abstract | Full text | PDF | PubMed

50.

Methodology article   Open Access Highly Accessed

Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes

Patrick Warnat, Roland Eils, Benedikt Brors BMC Bioinformatics 2005, 6:265 (4 November 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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