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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at DKFZ Heidelberg (Helmholtz Consortium)

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1.

Research article   Open Access

Comparison of survival of patients with metastases from known versus unknown primaries: survival in metastatic cancer

Matias Riihimäki, Hauke Thomsen, Akseli Hemminki, Kristina Sundquist, Kari Hemminki BMC Cancer 2013, 13:36 (28 January 2013)

Abstract | Full text | PDF | PubMed

2.

Research   Open Access

Intensity modulated radiotherapy (IMRT) combined with concurrent but not adjuvant chemotherapy in primary nasopharyngeal cancer -- a retrospective single center analysis

Ladan Saleh-Ebrahimi, Felix Zwicker, Marc W Muenter, Marc Bischof, Katja Lindel, Juergen Debus, Peter E Huber, Falk Roeder Radiation Oncology 2013, 8:20 (24 January 2013)

Abstract | Provisional PDF | PubMed

3.

Question & Answer   Open Access

Video Q&A: Excess body weight and cancer

Rudolf Kaaks BMC Medicine 2013, 11:2 (3 January 2013)

Full text | PDF | PubMed |  Editor’s summary

Rudolf Kaaks talks about types of cancers linked to the overweight and obesity epidemic, and advises that although weight loss may decrease the risk of developing cancer, ultimately prevention is better than the cure.

4.

Research   Open Access

Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment

Lars Wiechert, Julia Németh, Tobias Pusterla, Christine Bauer, Aurora De Ponti, Sandra Manthey, Silke Marhenke, Arndt Vogel, Ursula Klingmüller, Jochen Hess, Peter Angel Cell Communication and Signaling 2012, 10:40 (15 December 2012)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Intraoperative Electron Radiation Therapy (IOERT) in the management of locally recurrent rectal cancer

Falk Roeder, Joerg-Michael Goetz, Gregor Habl, Marc Bischof, Robert Krempien, Markus W Buechler, Frank W Hensley, Peter E Huber, Juergen Weitz, Juergen Debus BMC Cancer 2012, 12:592 (11 December 2012)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access

The protein interaction network of a taxis signal transduction system in a Halophilic Archaeon

Matthias Schlesner, Arthur Miller, Hüseyin Besir, Michalis Aivaliotis, Judith Streif, Beatrix Scheffer, Frank Siedler, Dieter Oesterhelt BMC Microbiology 2012, 12:272 (21 November 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

7.

Poster presentation   Open Access

A kinome-wide RNA interference screen identifies the microtubule affinity regulating kinase MARK4 as a new regulator of primary cilium formation

S Kuhns, K Schmidt, G Pereira Cilia 2012, 1(Suppl 1):P30 (16 November 2012)

Full text | PDF

8.

Research article   Open Access

Incidence and survival in non-hereditary amyloidosis in Sweden

Kari Hemminki, Xinjun Li, Asta Försti, Jan Sundquist, Kristina Sundquist BMC Public Health 2012, 12:974 (13 November 2012)

Abstract | Full text | PDF | PubMed

9.

Short report   Open Access

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

Richard J Mellanby, Helen Cambrook, Darryl G Turner, Richard A O’Connor, Melanie D Leech, Florian C Kurschus, Andrew S MacDonald, Bernd Arnold, Stephen M Anderton Journal of Neuroinflammation 2012, 9:248 (30 October 2012)

Abstract | Full text | PDF | PubMed

10.

Research   Open Access Highly Accessed

Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT): establishment of workflow and initial clinical data

Stephanie E Combs, Kerstin A Kessel, Klaus Herfarth, Alexandra Jensen, Susanne Oertel, Claudia Blattmann, Swantje Ecker, Angelika Hoess, Eike Martin, Olaf Witt, Oliver Jäkel, Andreas E Kulozik, Jürgen Debus Radiation Oncology 2012, 7:170 (17 October 2012)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access Highly Accessed

Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases

Stefanie Huhn, Melanie Bevier, Anja Rudolph, Barbara Pardini, Alessio Naccarati, Rebecca Hein, Michael Hoffmeister, Ludmila Vodickova, Jan Novotny, Hermann Brenner, Jenny Chang-Claude, Kari Hemminki, Pavel Vodicka, Asta Försti BMC Medical Genetics 2012, 13:94 (5 October 2012)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma

Kari Hemminki, Xiangdong Liu, Asta Försti, Jianguang Ji, Jan Sundquist, Kristina Sundquist Journal of Hematology & Oncology 2012, 5:59 (2 October 2012)

Abstract | Full text | PDF | PubMed

13.

Poster presentation   Open Access

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing

Natalie Jäger, David TW Jones, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae Cho, Trevor J Pugh, Volker Hovestadt, Adrian M Stütz, Tobias Rausch, Hans-Jörg Warnatz, Benedikt Brors, Paul A Northcott, Michael D Taylor, Matthew Meyerson, Scott L Pomeroy, Marie-Laure Yaspo, Jan O Korbel, Andrey Korshunov, Roland Eils, Stefan M Pfister, Peter Lichter BMC Proceedings 2012, 6(Suppl 6):P43 (1 October 2012)

Full text | PDF

14.

Research article   Open Access

Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters

David D O'Keefe, Sean R Thomas, Kelsey Bolin, Ellen Griggs, Bruce A Edgar, Laura A Buttitta BMC Genomics 2012, 13:498 (20 September 2012)

Abstract | Provisional PDF | PubMed

15.

Research   Open Access

Assisted reproductive techniques and the risk of anorectal malformations: a German case-control study

Nadine Zwink, Ekkehart Jenetzky, Eberhard Schmiedeke, Dominik Schmidt, Stefanie Märzheuser, Sabine Grasshoff-Derr, Stefan Holland-Cunz, Sandra Weih, Stuart Hosie, Peter Reifferscheid, Helen Ameis, Christina Kujath, Anke Rißmann, Florian Obermayr, Nicole Schwarzer, Enrika Bartels, Heiko Reutter, Hermann Brenner, Orphanet Journal of Rare Diseases 2012, 7:65 (15 September 2012)

Abstract | Full text | PDF | PubMed

16.

Study protocol   Open Access Highly Accessed

Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial

Vasileios Askoxylakis, Julien Dinkel, Monika Eichinger, Bram Stieltjes, Gregor Sommer, Ludwig G Strauss, Antonia Dimitrakopoulou-Strauss, Annette Kopp-Schneider, Uwe Haberkorn, Peter E Huber, Marc Bischof, Jürgen Debus, Christian Thieke Radiation Oncology 2012, 7:157 (14 September 2012)

Abstract | Full text | PDF | PubMed

17.

Research article   Open Access Highly Accessed

A novel multiplex-protein array for serum diagnostics of colon cancer: a case–control study

Stefanie Bünger, Ulrike Haug, Maria Kelly, Nicole Posorski, Katja Klempt-Giessing, Andrew Cartwright, Stephen P Fitzgerald, Vicki Toner, Damien McAleer, Timo Gemoll, Tilman Laubert, Jürgen Büning, Klaus Fellermann, Hans-Peter Bruch, Uwe J Roblick, Hermann Brenner, Ferdinand von Eggeling, Jens K Habermann BMC Cancer 2012, 12:393 (7 September 2012)

Abstract | Full text | PDF | PubMed

18.

Methodology article   Open Access

Conditional gene expression systems in the transgenic rat brain

Kai Schönig, Tillmann Weber, Ariana Frömmig, Lena Wendler, Brigitte Pesold, Dominik Djandji, Hermann Bujard, Dusan Bartsch BMC Biology 2012, 10:77 (3 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The advantages of rats over mice for biomedical research have to date been offset by a dearth of proven methods for their genetic manipulation. Addressing this deficit, Bartsch and coauthors develop transgenic rats with inducible reporter gene expression in forebrain neurons.

19.

Research   Open Access

IGRT versus non-IGRT for postoperative head-and-neck IMRT patients: dosimetric consequences arising from a PTV margin reduction

Michael Schwarz, Kristina Giske, Armin Stoll, Simeon Nill, Peter E Huber, Jürgen Debus, Rolf Bendl, Eva M Stoiber Radiation Oncology 2012, 7:133 (8 August 2012)

Abstract | Full text | PDF | PubMed

20.

Research highlight   Subscription Highly Accessed

The aging epigenome: DNA methylation from the cradle to the grave

Marc Winnefeld, Frank Lyko Genome Biology 2012, 13:165 (30 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Frank Lyko and Marc Winnefeld highlight a new survey of age-related epigenetic changes in newborn and centenarian methylomes

21.

Research article   Open Access

Trends of population-based breast cancer survival in Germany and the US: Decreasing discrepancies, but persistent survival gap of elderly patients in Germany

Bernd Holleczek, Hermann Brenner BMC Cancer 2012, 12:317 (28 July 2012)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Connection of European particle therapy centers and generation of a common particle database system within the European ULICE-framework

Kerstin A Kessel, Nina Bougatf, Christian Bohn, Daniel Habermehl, Dieter Oetzel, Rolf Bendl, Uwe Engelmann, Roberto Orecchia, Piero Fossati, Richard Pötter, Manjit Dosanjh, Jürgen Debus, Stephanie E Combs Radiation Oncology 2012, 7:115 (24 July 2012)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Aggressive local treatment containing intraoperative radiation therapy (IORT) for patients with isolated local recurrences of pancreatic cancer: a retrospective analysis

Falk Roeder, Carmen Timke, Matthias Uhl, Gregor Habl, Frank W Hensley, Markus W Buechler, Robert Krempien, Peter E Huber, Juergen Debus, Jens Werner BMC Cancer 2012, 12:295 (18 July 2012)

Abstract | Full text | PDF | PubMed

24.

Study protocol   Open Access

A Clinical phase I/II trial to investigate preoperative dose-escalated intensity-modulated radiation therapy (IMRT) and intraoperative radiation therapy (IORT) in patients with retroperitoneal soft tissue sarcoma

Falk Roeder, Daniela Schulz-Ertner, Anna V Nikoghosyan, Peter E Huber, Lutz Edler, Gregor Habl, Robert Krempien, Susanne Oertel, Ladan Saleh-Ebrahimi, Frank W Hensley, Markus W Buechler, Juergen Debus, Moritz Koch, Juergen Weitz, Marc Bischof BMC Cancer 2012, 12:287 (12 July 2012)

Abstract | Full text | PDF | PubMed

25.

Research article   Open Access

Real-imaging cDNA-AFLP transcript profiling of pancreatic cancer patients: Egr-1 as a potential key regulator of muscle cachexia

Alexander Skorokhod, Jeannine Bachmann, Nathalia A Giese, Marc E Martignoni, Holger Krakowski-Roosen BMC Cancer 2012, 12:265 (21 June 2012)

Abstract | Full text | PDF | PubMed

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