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1.

Study protocol   Open Access

Rationale and design of a randomized controlled trial of the effect of retinol and vitamin D supplementation on treatment in active pulmonary tuberculosis patients with diabetes

Qiuzhen Wang, Aiguo Ma, Ib Christian Bygbjerg, Xiuxia Han, Yufeng Liu, Shanliang Zhao, Jing Cai BMC Infectious Diseases 2013, 13:104 (26 February 2013)

Abstract | Provisional PDF | PubMed

2.

Commentary   Open Access

Predicting the evolution of antibiotic resistance

Martijn F Schenk, J Arjan GM de Visser BMC Biology 2013, 11:14 (22 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Commenting on research in BMC Evolutionary Biology, Arjan de Visser and Martijn Schenk discuss how two genetic properties, pleiotropy and epistasis, might help us to predict the evolution of antibiotic resistance.

3.

Research   Open Access

Fast probabilistic file fingerprinting for big data

Konstantin Tretyakov, Sven Laur, Geert Smant, Jaak Vilo, Pjotr Prins BMC Genomics 2013, 14(Suppl 2):S8 (15 February 2013)

Abstract | Full text | PDF

4.

Review   Open Access

The 3rd DBCLS BioHackathon: improving life science data integration with semantic Web technologies

Toshiaki Katayama, Mark D Wilkinson, Gos Micklem, Shuichi Kawashima, Atsuko Yamaguchi, Mitsuteru Nakao, Yasunori Yamamoto, Shinobu Okamoto, Kenta Oouchida, Hong-Woo Chun, Jan Aerts, Hammad Afzal, Erick Antezana, Kazuharu Arakawa, Bruno Aranda, Francois Belleau, Jerven Bolleman, Raoul Jean Bonnal, Brad Chapman, Peter Cock, Tore Eriksson, Paul Gordon, Naohisa Goto, Kazuhiro Hayashi, Heiko Horn, Ryosuke Ishiwata, Eli Kaminuma, Arek Kasprzyk, Hideya Kawaji, Nobuhiro Kido et al. Journal of Biomedical Semantics 2013, 4:6 (11 February 2013)

Abstract | Provisional PDF | PubMed

5.

Research article   Open Access

Genome-wide gene expression analysis of anguillid herpesvirus 1

Steven J Beurden, Ben PH Peeters, Peter JM Rottier, Andrew J Davison, Marc Y Engelsma BMC Genomics 2013, 14:83 (6 February 2013)

Abstract | Provisional PDF | PubMed

6.

Research article   Open Access

Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data

Kristina M Hettne, André Boorsma, Dorien A M van Dartel, Jelle J Goeman, Esther de Jong, Aldert H Piersma, Rob H Stierum, Jos C Kleinjans, Jan A Kors BMC Medical Genomics 2013, 6:2 (29 January 2013)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Geographic parthenogenesis and plant-enemy interactions in the common dandelion

Koen JF Verhoeven, Arjen Biere BMC Evolutionary Biology 2013, 13:23 (28 January 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access Highly Accessed

Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease

Lotta Nylund, Reetta Satokari, Janne Nikkilä, Mirjana Rajilić-Stojanović, Marko Kalliomäki, Erika Isolauri, Seppo Salminen, Willem M de Vos BMC Microbiology 2013, 13:12 (23 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Children with eczema harbour a greater diversity of microbes in the gut than those without, including an increased abundance of bacteria that are typically more common in adults, which may contribute to the perpetuation of the condition.

9.

Research   Open Access Highly Accessed

Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages

Tanya L Russell, Dickson W Lwetoijera, Bart GJ Knols, Willem Takken, Gerry F Killeen, Louise A Kelly-Hope Malaria Journal 2013, 12:24 (18 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Malaria elimination necessitates an improved understanding of fine-scale geographic variations in transmission risk so that complementary vector control tools can be integrated into control programmes.

10.

Short report   Open Access Highly Accessed

Systemic distribution of different low pathogenic avian influenza (LPAI) viruses in chicken

Jacob Post, Eveline D de Geus, Lonneke Vervelde, Jan BWJ Cornelissen, Johanna MJ Rebel Virology Journal 2013, 10:23 (17 January 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

RNA-Seq analysis reveals new gene models and alternative splicing in the fungal pathogen Fusarium graminearum

Chunzhao Zhao, Cees Waalwijk, Pierre J G M de Wit, Dingzhong Tang, Theo van der Lee BMC Genomics 2013, 14:21 (16 January 2013)

Abstract | Full text | PDF | PubMed

12.

Short report   Open Access

Anemia in relation to body mass index and waist circumference among chinese women

Yu Qin, Alida Melse-Boonstra, Xiaoqun Pan, Baojun Yuan, Yue Dai, Jinkou Zhao, Michael B Zimmermann, Frans J Kok, Minghao Zhou, Zumin Shi Nutrition Journal 2013, 12:10 (11 January 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Association between transmission rate and disease severity for Actinobacillus pleuropneumoniae infection in pigs

Tijs J Tobias, Annemarie Bouma, Angeline JJM Daemen, Jaap A Wagenaar, Arjan Stegeman, Don Klinkenberg Veterinary Research 2013, 44:2 (11 January 2013)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access

‘Everybody knows’, but the rest of the world: the case of a caterpillar-borne reproductive loss syndrome in dromedary camels observed by Sahrawi pastoralists of Western Sahara

Gabriele Volpato, Antonello Di Nardo, Davide Rossi, Saleh M Lamin Saleh, Alessandro Broglia Journal of Ethnobiology and Ethnomedicine 2013, 9:5 (10 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

Opinion   Open Access

Integration of gastronomy and physics for innovation

Erik van der Linden Flavour 2013, 2:11 (9 January 2013)

Abstract | Full text | PDF

16.

Methodology article   Open Access

A simplified counter-selection recombineering protocol for creating fluorescent protein reporter constructs directly from C. elegans fosmid genomic clones

Nisha Hirani, Marcel Westenberg, Minaxi S Gami, Paul Davis, Ian A Hope, Colin T Dolphin BMC Biotechnology 2013, 13:1 (3 January 2013)

Abstract | Full text | PDF | PubMed

17.

Research   Open Access

Biocatalytic potential of laccase-like multicopper oxidases from Aspergillus niger

Juan Antonio Tamayo-Ramos, Willem JH van Berkel, Leo H de Graaff Microbial Cell Factories 2012, 11:165 (27 December 2012)

Abstract | Full text | PDF | PubMed

18.

Research   Open Access Highly Accessed

Healing war wounds and perfuming exile: the use of vegetal, animal, and mineral products for perfumes, cosmetics, and skin healing among Sahrawi refugees of Western Sahara

Gabriele Volpato, Pavlína Kourková, Václav Zelený Journal of Ethnobiology and Ethnomedicine 2012, 8:49 (27 December 2012)

Abstract | Full text | PDF | PubMed

19.

Research article   Open Access

In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A

Marcela de Azevedo, Jurgen Karczewski, François Lefévre, Vasco Azevedo, Anderson Miyoshi, Jerry M Wells, Philippe Langella, Jean-Marc Chatel BMC Microbiology 2012, 12:299 (19 December 2012)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

Circumstantial evidence for an increase in the total number and activity of borrelia-infected ixodes ricinus in the Netherlands

Hein Sprong, Agnetha Hofhuis, Fedor Gassner, Willem Takken, Frans Jacobs, Arnold JH van Vliet, Marijn van Ballegooijen, Joke van der Giessen, Katsuhisa Takumi Parasites & Vectors 2012, 5:294 (17 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In The Netherlands, the incidence of Lyme disease has been on the rise since 1994. Here, we investigated whether the abundance of questing Ixodes ricinus infected with the Lyme spirochete has increased concomitantly. Image: Questing female Ixodes ricinus. Courtsey: Hans Smid (http://www.bugsinthepicture.com/).

21.

Research article   Open Access Highly Accessed

Healthy snacks at the checkout counter: A lab and field study on the impact of shelf arrangement and assortment structure on consumer choices

Ellen van Kleef, Kai Otten, Hans CM van Trijp BMC Public Health 2012, 12:1072 (12 December 2012)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access Highly Accessed

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

Frank Koopman, Jules Beekwilder, Barbara Crimi, Adele van Houwelingen, Robert D Hall, Dirk Bosch, Antonius JA van Maris, Jack T Pronk, Jean-Marc Daran Microbial Cell Factories 2012, 11:155 (8 December 2012)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Modeling and analysis of flux distributions in the two branches of the phosphotransferase system in Pseudomonas putida

Andreas Kremling, Katharina Pflüger-Grau, Max Chavarría, Jacek Puchalka, Vitor Martins dos Santos, Víctor de Lorenzo BMC Systems Biology 2012, 6:149 (6 December 2012)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

Domestic dog demographic structure and dynamics relevant to rabies control planning in urban areas in Africa: the case of Iringa, Tanzania

Alena S Gsell, Darryn L Knobel, Rudovick R Kazwala, Penelope Vounatsou, Jakob Zinsstag BMC Veterinary Research 2012, 8:236 (5 December 2012)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access

Differential effects of exposure to ambient vanilla and citrus aromas on mood, arousal and food choice

René A de Wijk, Suzet M Zijlstra Flavour 2012, 1:24 (1 December 2012)

Abstract | Full text | PDF |  Editor’s summary

Differential effects of exposure to ambient vanilla and citrus aromas on mood, arousal and food choice

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