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1.

Methodology article   Open Access

An endogenous artificial microRNA system for unraveling the function of root endosymbioses related genes in Medicago truncatula

Emanuel A Devers, Julia Teply, Armin Reinert, Nicole Gaude, Franziska Krajinski BMC Plant Biology 2013, 13:82 (16 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

An artificial microRNA (amiR)-mediated gene silencing system for Medicago truncatula roots sheds light on the function of MtErf1, a putative transcription factor that is strongly induced in arbuscule-containing cells during mycorrhizal symbiosis.

2.

Methodology article   Open Access

Foamy virus for efficient gene transfer in regeneration studies

Shahryar Khattak, Tatiana Sandoval-Guzmán, Nicole Stanke, Stephanie Protze, Elly M Tanaka, Dirk Lindemann BMC Developmental Biology 2013, 13:17 (3 May 2013)

Abstract | Full text | PDF | PubMed

3.

Research article   Open Access

NaMYC2 transcription factor regulates a subset of plant defense responses in Nicotiana attenuata

Melkamu G Woldemariam, Son Truong Dinh, Youngjoo Oh, Emmanuel Gaquerel, Ian T Baldwin, Ivan Galis BMC Plant Biology 2013, 13:73 (1 May 2013)

Abstract | Full text | PDF | PubMed

4.

Methodology article   Open Access Highly Accessed

Evolution of MHC class I genes in the endangered loggerhead sea turtle (Caretta caretta) revealed by 454 amplicon sequencing

Victor A Stiebens, Sonia E Merino, Frédéric J J Chain, Christophe Eizaguirre BMC Evolutionary Biology 2013, 13:95 (30 April 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Silencing of Nicotiana benthamiana Neuroblastoma-Amplified Gene causes ER stress and cell death

Jae-Yong Lee, Sujon Sarowar, Hee Seung Kim, Hyeran Kim, Inhwan Hwang, Young Jin Kim, Hyun-Sook Pai BMC Plant Biology 2013, 13:69 (27 April 2013)

Abstract | Full text | PDF | PubMed

6.

Opinion   Subscription Highly Accessed

Sixty years of genome biology

W Doolittle, Peter Fraser, Mark B Gerstein, Brenton R Graveley, Steven Henikoff, Curtis Huttenhower, Alicia Oshlack, Chris P Ponting, John L Rinn, Michael C Schatz, Jernej Ule, Detlef Weigel, George M Weinstock Genome Biology 2013, 14:113 (25 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Members of Genome Biology's Editorial Board select their highlights from the 60 years of genome biology that followed the double helix

7.

Research   Open Access

Ecological characterization of soil-inhabiting and hypolithic soil crusts within the Knersvlakte, South Africa

Bettina Weber, Dirk CJ Wessels, Kirstin Deutschewitz, Stephanie Dojani, Hans Reichenberger, Burkhard Büdel Ecological Processes 2013, 2:8 (24 April 2013)

Abstract | Full text | PDF

8.

Research   Open Access

Patient-reported outcomes in adequately treated hypothyroidism – insights from the German versions of ThyDQoL, ThySRQ and ThyTSQ

Eva M Quinque, Arno Villringer, Juergen Kratzsch, Stefan Karger Health and Quality of Life Outcomes 2013, 11:68 (23 April 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

LocARNAscan: Incorporating thermodynamic stability in sequence and structure-based RNA homology search

Sebastian Will, Michael F. Siebauer, Steffen Heyne, Jan Engelhardt, Peter F. Stadler, Kristin Reiche, Rolf Backofen Algorithms for Molecular Biology 2013, 8:14 (20 April 2013)

Abstract | Provisional PDF | PubMed

10.

Review   Subscription Highly Accessed

Neurogenomics of speech and language disorders: the road ahead

Pelagia Deriziotis, Simon E Fisher Genome Biology 2013, 14:204 (18 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

From GWAS to Neanderthal genomes: Fisher and Deriziotis review what genomics can teach us about speech, language and their associated disorders

11.

Research article   Open Access Highly Accessed

Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator

Philip Vlaicu, Philipp Mertins, Thomas Mayr, Peter Widschwendter, Beyhan Ataseven, Bernhard Högel, Wolfgang Eiermann, Pjotr Knyazev, Axel Ullrich BMC Cancer 2013, 13:197 (18 April 2013)

Abstract | Full text | PDF | PubMed

12.

Research article   Open Access Highly Accessed

Inferring the evolutionary histories of divergences in Hylobates and Nomascus gibbons through multilocus sequence data

Yi-Chiao Chan, Christian Roos, Miho Inoue-Murayama, Eiji Inoue, Chih-Chin Shih, Kurtis Jai-Chyi Pei, Linda Vigilant BMC Evolutionary Biology 2013, 13:82 (12 April 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Phylostratigraphic profiles reveal a deep evolutionary history of the vertebrate head sensory systems

Martin Sebastijan Šestak, Vedran Božičević, Robert Bakarić, Vedran Dunjko, Tomislav Domazet-Lošo Frontiers in Zoology 2013, 10:18 (12 April 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Lophelia pertusa corals from the Ionian and Barents seas share identical nuclear ITS2 and near-identical mitochondrial genome sequences

Jean-François Flot, Mikael Dahl, Carl André BMC Research Notes 2013, 6:144 (11 April 2013)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access

Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions

Satyendra K Singh, Alena Bencsik-Theilen, Emil Mladenov, Burkhard Jakob, Gisela Taucher-Scholz, George Iliakis Radiation Oncology 2013, 8:77 (2 April 2013)

Abstract | Full text | PDF | PubMed

16.

Review   Open Access Highly Accessed

Immunosenescence in vertebrates and invertebrates

Ludmila Müller, Tamas Fülöp, Graham Pawelec Immunity & Ageing 2013, 10:12 (2 April 2013)

Abstract | Full text | PDF | PubMed

17.

Research   Open Access Highly Accessed

Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care

Martin J Llewelyn, Mario Berger, Mark Gregory, Ravi Ramaiah, Amanda L Taylor, Ingo Curdt, Frédéric Lajaunias, Rolf Graf, Stuart J Blincko, Stephen Drage, Jonathan Cohen Critical Care 2013, 17:R60 (26 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

Review   Subscription

Proteomic profiling in schizophrenia: enabling stratification for more effective treatment

Paul C Guest, Daniel Martins-de-Souza, Emanuel Schwarz, Hassan Rahmoune, Murtada Alsaif, Jakub Tomasik, Christoph W Turck, Sabine Bahn Genome Medicine 2013, 5:25 (26 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Sabine Bahn and colleagues review the impact of studying co-morbidities and the use of proteomic profiling on the future of schizophrenia diagnosis and therapeutics.

19.

Poster presentation   Open Access

Deterministic clustering of the available chemical space

Philipp Thiel, Lisa Peltason, Christian Ottmann, Oliver Kohlbacher Journal of Cheminformatics 2013, 5(Suppl 1):P53 (22 March 2013)

Full text | PDF

20.

Research article   Open Access Highly Accessed

Antennal transcriptome analysis of the chemosensory gene families in the tree killing bark beetles, Ips typographus and Dendroctonus ponderosae (Coleoptera: Curculionidae: Scolytinae)

Martin N Andersson, Ewald Grosse-Wilde, Christopher I Keeling, Jonas M Bengtsson, Macaire MS Yuen, Maria Li, Ylva Hillbur, Jörg Bohlmann, Bill S Hansson, Fredrik Schlyter BMC Genomics 2013, 14:198 (21 March 2013)

Abstract | Full text | PDF | PubMed

21.

Research   Open Access

Pre-analytical stability of the plasma proteomes based on the storage temperature

Sara Pasella, Angela Baralla, Elisabetta Canu, Sara Pinna, James Vaupel, Marta Deiana, Claudio Franceschi, Giovannella Baggio, Angelo Zinellu, Salvatore Sotgia, Giuseppe Castaldo, Ciriaco Carru, Luca Deiana Proteome Science 2013, 11:10 (21 March 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Heterogeneous resource federation with a centralized security model for information extraction

Milad Daivandy, Denis Hünich, René Jäkel, Steffen Metzger, Ralph Müller-Pfefferkorn, Bernd Schuller Journal of Internet Services and Applications 2013, 4:10 (20 March 2013)

Abstract | Provisional PDF

23.

Research   Open Access

The whole mesh deformation model: a fast image segmentation method suitable for effective parallelization

Przemyslaw Lenkiewicz, Manuela Pereira, Mário M Freire, José Fernandes EURASIP Journal on Advances in Signal Processing 2013, 2013:55 (19 March 2013)

Abstract | Full text | PDF

24.

Oral presentation   Open Access

Towards a causative function of histone modifications in regulation of chromatin dynamics and transcription

Philipp Tropberger, Sebastian Pott, Kinga Kamieniarz, Matthieu Caron, Edison T Liu, Raphael Margueron, Robert Schneider Epigenetics & Chromatin 2013, 6(Suppl 1):O30 (18 March 2013)

Full text | PDF

25.

Poster presentation   Open Access

Kinetic control of nucleosome displacement by ISWI/ACF chromatin remodelers

Ana-Maria Florescu, Helmut Schiessel, Ralf Blossey Epigenetics & Chromatin 2013, 6(Suppl 1):P7 (18 March 2013)

Full text | PDF

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