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101.

Research   Open Access Highly Accessed

Probiotics' effects on the incidence of nosocomial pneumonia in critically ill patients: a systematic review and meta-analysis

Kai-xiong Liu, Ying-gang Zhu, Jing Zhang, Li-li Tao, Jae-Woo Lee, Xiao-dan Wang, Jie-ming Qu Critical Care 2012, 16:R109 (25 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

102.

Research   Open Access Highly Accessed

Time to definitive diagnosis of breast cancer in Latina and non-Hispanic white women: the six cities study

Amelie G Ramirez, Eliseo J Pérez-Stable, Gregory A Talavera, Frank J Penedo, J Emilio Carrillo, Maria E Fernandez, Edgar Muñoz, Dorothy Long Parma, Alan EC Holden, Sandra San Miguel de Majors, Anna Nápoles, Sheila F Castañeda, Kipling J Gallion SpringerPlus 2013, 2:84 (5 March 2013)

Abstract | Full text | PDF

103.

Research   Open Access

Availability, prices and affordability of the World Health Organization’s essential medicines for children in Guatemala

Angela Anson, Brooke Ramay, Antonio de Esparza, Lisa Bero Globalization and Health 2012, 8:22 (2 July 2012)

Abstract | Full text | PDF | PubMed

104.

Editorial   Free

The C9ORF72 mutation brings more answers and more questions

Bruce L Miller Alzheimer's Research & Therapy 2013, 5:7 (18 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Bruce Miller, Guest Editor of the special series: The new FTD mutation on chromosome 9, discusses the C9ORF72 mutation associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis.

105.

Research article   Open Access

Knowledge translation of the HELPinKIDS clinical practice guideline for managing childhood vaccination pain: usability and knowledge uptake of educational materials directed to new parents

Anna Taddio, Vibhuti Shah, Eman Leung, Jane Wang, Chaitya Parikh, Sarah Smart, Ross Hetherington, Moshe Ipp, Rebecca Pillai Riddell, Michael Sgro, Aleksandra Jovicic, Linda Franck BMC Pediatrics 2013, 13:23 (8 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An educational pamphlet and video effectively increase parental knowledge about managing vaccination pain in children, suggesting that these educational tools may influence parent behaviors during infant vaccinations in clinical settings.

106.

Review   Open Access

John Widdicombe’s contribution to respiratory physiology and cough: reminiscences

Kian Fan Chung, Jay A Nadel, Giovanni Fontana Cough 2013, 9:6 (6 March 2013)

Abstract | Full text | PDF | PubMed

107.

Research article   Open Access Highly Accessed

Potential for false positive HIV test results with the serial rapid HIV testing algorithm

Steven Baveewo, Moses R Kamya, Harriet Mayanja-Kizza, Robin Fatch, David R Bangsberg, Thomas Coates, Judith A Hahn, Rhoda K Wanyenze BMC Research Notes 2012, 5:154 (19 March 2012)

Abstract | Full text | PDF | PubMed

108.

Research article   Open Access

Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes

Colleen A Fordyce, Kelley T Patten, Tim B Fessenden, RosaAnna DeFilippis, E Shelley Hwang, Jianxin Zhao, Thea D Tlsty Breast Cancer Research 2012, 14:R155 (7 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

109.

Research   Open Access Highly Accessed

Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice

Jianteng Gu, Pamela Sun, Hailin Zhao, Helena R Watts, Robert D Sanders, Niccolo Terrando, Peiyuan Xia, Mervyn Maze, Daqing Ma Critical Care 2011, 15:R153 (24 June 2011)

Abstract | Full text | PDF | PubMed

110.

Study protocol   Open Access Highly Accessed

Assessing the outcomes of participatory research: protocol for identifying, selecting, appraising and synthesizing the literature for realist review

Justin Jagosh, Pierre Pluye, Ann C Macaulay, Jon Salsberg, Jim Henderson, Erin Sirett, Paula L Bush, Robbyn Seller, Geoff Wong, Trish Greenhalgh, Margaret Cargo, Carol P Herbert, Sarena D Seifer, Lawrence W Green Implementation Science 2011, 6:24 (20 March 2011)

Abstract | Full text | PDF | PubMed

111.

Review   Open Access Highly Accessed

Roles of planar cell polarity pathways in the development of neutral tube defects

Gang Wu, Xupei Huang, Yimin Hua, Dezhi Mu Journal of Biomedical Science 2011, 18:66 (24 August 2011)

Abstract | Full text | PDF | PubMed

112.

Research   Open Access Highly Accessed

Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial

Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, Critical Care 2010, 14:R38 (16 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Medicine | F1000 Biology

113.

Research   Open Access Highly Accessed

An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data

Katarzyna Bozek, Manon Eckhardt, Saleta Sierra, Maria Anders, Rolf Kaiser, Hans-Georg Kräusslich, Barbara Müller, Thomas Lengauer Retrovirology 2012, 9:60 (25 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study developed a multivariate phenotype descriptor, termed phenotype vector, which facilitates a more detailed characterization of HIV entry phenotypes than currently used binary tropism classifications. For some of the tested virus variants, the multivariant phenotype vector revealed substantial divergences from existing tropism predictions.

114.

Short report   Open Access Highly Accessed

A novel bocavirus in canine liver

Linlin Li, Patricia A Pesavento, Christian M Leutenegger, Marko Estrada, Lark L Coffey, Samia N Naccache, Erik Samayoa, Charles Chiu, Jianming Qiu, Chunlin Wang, Xutao Deng, Eric Delwart Virology Journal 2013, 10:54 (13 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A new species of bocavirus has been identified in the liver of a dog with haemorrhagic gastoenteritis and is highly genetically distinct from the two known canine bocaviruses.

115.

Correspondence   Open Access Highly Accessed

Public health triangulation: approach and application to synthesizing data to understand national and local HIV epidemics

George W Rutherford, William McFarland, Hilary Spindler, Karen White, Sadhna V Patel, John Aberle-Grasse, Keith Sabin, Nathan Smith, Stephanie Taché, Jesus M Calleja-Garcia, Rand L Stoneburner BMC Public Health 2010, 10:447 (29 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

116.

Research article   Open Access Highly Accessed

Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies

Suzanne R Kalb, Wanda I Santana, Isin N Geren, Consuelo Garcia-Rodriguez, Jianlong Lou, Theresa J Smith, James D Marks, Leonard A Smith, James L Pirkle, John R Barr BMC Biochemistry 2011, 12:58 (15 November 2011)

Abstract | Full text | PDF | PubMed

117.

Research   Open Access

Quantification of the physiochemical constraints on the export of spider silk proteins by Salmonella type III secretion

Daniel M Widmaier, Christopher A Voigt Microbial Cell Factories 2010, 9:78 (25 October 2010)

Abstract | Full text | PDF | PubMed

118.

Research   Open Access

How is the balance between protein synthesis and degradation achieved?

Stephen Rothman Theoretical Biology and Medical Modelling 2010, 7:25 (23 June 2010)

Abstract | Full text | PDF | PubMed

119.

Research   Open Access

Gel versus capillary electrophoresis genotyping for categorizing treatment outcomes in two anti-malarial trials in Uganda

Vinay Gupta, Grant Dorsey, Alan E Hubbard, Philip J Rosenthal, Bryan Greenhouse Malaria Journal 2010, 9:19 (15 January 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper presents strong evidence that capillary electrophoresis (CE) is better than gel electrophoresis in discriminating recrudescence from reinfection. This has important implications for drug development.

120.

Research   Open Access

HIV serostatus disclosure is not associated with safer sexual behavior among HIV-positive men who have sex with men (MSM) and their partners at risk for infection in Bangkok, Thailand

Nneka Edwards-Jackson, Nittaya Phanuphak, Hong Van Tieu, Nitiya Chomchey, Nipat Teeratakulpisarn, Wassana Sathienthammawit, Charnwit Pakam, Nutthasun Pharachetsakul, Magdalena E Sobieszczyk, Praphan Phanuphak, Jintanat Ananworanich AIDS Research and Therapy 2012, 9:38 (23 December 2012)

Abstract | Full text | PDF | PubMed

121.

Research   Open Access

Human Endogenous Retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods

R Brad Jones, Fabio E Leal, Aaron M Hasenkrug, Aluisio C Segurado, Douglas F Nixon, Mario A Ostrowski, Esper G Kallas Journal of Negative Results in BioMedicine 2013, 12:3 (10 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The elicitation of human endogenous retrovirus (HERV)-specific T-cells responses may not have a role in human T-cell leukemia virus type 1 (HTLV-1) associated immunopathology suggests this study.

122.

Research article   Open Access

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity

Umesh Masharani, Christine Gjerde, Shelley McCoy, Betty A Maddux, Danielle Hessler, Ira D Goldfine, Jack F Youngren BMC Endocrine Disorders 2012, 12:31 (30 November 2012)

Abstract | Full text | PDF | PubMed

123.

Research   Open Access Highly Accessed

Reliability and development of a new classification of lumbosacral spondylolisthesis

Jean-Marc Mac-Thiong, Hubert Labelle, Stefan Parent, Michael Hresko, Vedat Deviren, Mark Weidenbaum, Scoliosis 2008, 3:19 (10 December 2008)

Abstract | Full text | PDF | PubMed

124.

Case study   Open Access Highly Accessed

Impact of home-based management of malaria on health outcomes in Africa: a systematic review of the evidence

Heidi Hopkins, Ambrose Talisuna, Christopher JM Whitty, Sarah G Staedke Malaria Journal 2007, 6:134 (8 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Home-based management of malaria, which involves presumptively treating febrile children with pre-packaged antimalarial drugs distributed by members of the community, is promoted as a major strategy to improve prompt delivery of effective malaria treatment in Africa. Of 1,069 potentially relevant publications identified, only six studies were identified as meeting inclusion criteria. Heterogeneity of the evaluations, including variability in study design, precluded meta-analysis and overall results were mixed.

125.

Research   Open Access Highly Accessed

Malaria indicator survey 2007, Ethiopia: coverage and use of major malaria prevention and control interventions

Daddi Jima, Asefaw Getachew, Hana Bilak, Richard W Steketee, Paul M Emerson, Patricia M Graves, Teshome Gebre, Richard Reithinger, Jimee Hwang, Malaria Journal 2010, 9:58 (24 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An important finding and conclusion from this study is that although there have been massive gains in intervention coverage in Ethiopia, there is still some work required to make sure that the interventions are used.

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