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1.

Research article   Open Access Highly Accessed

Novel core promoter elements in the oomycete pathogen Phytophthora infestans and their influence on expression detected by genome-wide analysis

Sourav Roy, Laetitia Poidevin, Tao Jiang, Howard S Judelson BMC Genomics 2013, 14:106 (16 February 2013)

Abstract | Provisional PDF | PubMed

2.

Original research   Open Access

Agonist and antagonist binding to the nuclear vitamin D receptor: dynamics, mutation effects and functional implications

Sepideh Yaghmaei, Christopher Roberts, Rizi Ai, Mathew T Mizwicki, Chia-en A Chang In Silico Pharmacology 2013, 1:2 (12 February 2013)

Abstract | Full text | PDF

3.

Research article   Open Access

Comparison of class 2 transposable elements at superfamily resolution reveals conserved and distinct features in cereal grass genomes

Yujun Han, Shanshan Qin, Susan R Wessler BMC Genomics 2013, 14:71 (31 January 2013)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access Highly Accessed

Molecular decay of enamel matrix protein genes in turtles and other edentulous amniotes

Robert W Meredith, John Gatesy, Mark S Springer BMC Evolutionary Biology 2013, 13:20 (23 January 2013)

Abstract | Full text | PDF | PubMed

5.

Proceedings   Open Access

A linear-time algorithm for reconstructing zero-recombinant haplotype configuration on a pedigree

En-Yu Lai, Wei-Bung Wang, Tao Jiang, Kun-Pin Wu BMC Bioinformatics 2012, 13(Suppl 17):S19 (13 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

Proceedings   Open Access

A fast and accurate algorithm for single individual haplotyping

Minzhu Xie, Jianxin Wang, Tao Jiang BMC Systems Biology 2012, 6(Suppl 2):S8 (12 December 2012)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Analyses of expressed sequence tags in Neurospora reveal rapid evolution of genes associated with the early stages of sexual reproduction in fungi

Kristiina Nygren, Andreas Wallberg, Nicklas Samils, Jason E Stajich, Jeffrey P Townsend, Magnus Karlsson, Hanna Johannesson BMC Evolutionary Biology 2012, 12:229 (27 November 2012)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

A reference genetic map of C. clementina hort. ex Tan.; citrus evolution inferences from comparative mapping

Patrick Ollitrault, Javier Terol, Chunxian Chen, Claire T Federici, Samia Lotfy, Isabelle Hippolyte, Frédérique Ollitrault, Aurélie Bérard, Aurélie Chauveau, Jose Cuenca, Gilles Costantino, Yildiz Kacar, Lisa Mu, Andres Garcia-Lor, Yann Froelicher, Pablo Aleza, Anne Boland, Claire Billot, Luis Navarro, François Luro, Mikeal L Roose, Frederick G Gmitter, Manuel Talon, Dominique Brunel BMC Genomics 2012, 13:593 (5 November 2012)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells

Gang Chen, Maiara S Severo, Mohammad Sohail, Olivia S Sakhon, Stephen K Wikel, Michail Kotsyfakis, Joao HF Pedra Parasites & Vectors 2012, 5:229 (10 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study demonstrates that Ixodes scapularis saliva inhibits Toll-like (TLR) and Nod-like receptor (NLR) induced-inflammatory cytokine secretion by mouse and human immune cells. I. scapularis saliva also mitigates the cytokine response by macrophages during challenge with Anaplasma phagocytophilum. Image: Anaplasma phagocytophilum engulfed by macrophages [membranes (green), A. phagocytophilum (red), and nuclei (blue)]. Magnification is 600x4=2400.

10.

Research   Open Access Highly Accessed

Separating metagenomic short reads into genomes via clustering

Olga Tanaseichuk, James Borneman, Tao Jiang Algorithms for Molecular Biology 2012, 7:27 (26 September 2012)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access Highly Accessed

High throughput sequencing reveals novel and abiotic stress-regulated microRNAs in the inflorescences of rice

Blanca E Barrera-Figueroa, Lei Gao, Zhigang Wu, Xuefeng Zhou, Jianhua Zhu, Hailing Jin, Renyi Liu, Jian-Kang Zhu BMC Plant Biology 2012, 12:132 (3 August 2012)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

Rapid selection and identification of Miscanthus genotypes with enhanced glucan and xylan yields from hydrothermal pretreatment followed by enzymatic hydrolysis

Taiying Zhang, Charles E Wyman, Katrin Jakob, Bin Yang Biotechnology for Biofuels 2012, 5:56 (3 August 2012)

Abstract | Full text | PDF | PubMed

13.

Research article   Open Access

Leaf morphology in Cowpea [Vigna unguiculata (L.) Walp]: QTL analysis, physical mapping and identifying a candidate gene using synteny with model legume species

Marti Pottorff, Jeffrey D Ehlers, Christian Fatokun, Philip A Roberts, Timothy J Close BMC Genomics 2012, 13:234 (12 June 2012)

Abstract | Full text | PDF | PubMed

14.

Methods   Open Access

Development of a luciferase-based reporter of transcriptional gene silencing that enables bidirectional mutant screening in Arabidopsis thaliana

So Youn Won, Shengben Li, Binglian Zheng, Yuanyuan Zhao, Dongming Li, Xin Zhao, Huilan Yi, Lei Gao, Thanh Theresa Dinh, Xuemei Chen Silence 2012, 3:6 (7 June 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A luciferase-based reporter system, LUCH, is used to screen for bidirectional mutants that enhance or suppress transcriptional gene silencing, elucidating the mechanisms of DNA methylation and demethylation.

15.

Methodology article   Open Access

Development and application of a 6.5 million feature Affymetrix Genechip® for massively parallel discovery of single position polymorphisms in lettuce (Lactuca spp.)

Kevin Stoffel, Hans van Leeuwen, Alexander Kozik, David Caldwell, Hamid Ashrafi, Xinping Cui, Xiaoping Tan, Theresa Hill, Sebastian Reyes-Chin-Wo, Maria-Jose Truco, Richard W Michelmore, Allen Van Deynze BMC Genomics 2012, 13:185 (14 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

Review   Open Access

Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation

Shahani Noor, Emma H Wilson Journal of Neuroinflammation 2012, 9:77 (25 April 2012)

Abstract | Full text | PDF | PubMed

17.

Software   Open Access Highly Accessed

The Transcription Factor Encyclopedia

Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Warren A Cheung, Xiao Cindy Zhang, Christopher TD Dickman, Debra L Fulton, Jonathan S Lim, Jake M Schnabl, Oscar HP Ramos, Mireille Vasseur-Cognet, Charles N de Leeuw, Elizabeth M Simpson, Gerhart U Ryffel, Eric W-F Lam, Ralf Kist, Miranda SC Wilson, Raquel Marco-Ferreres, Jan J Brosens, Leonardo L Beccari, Paola Bovolenta, Bérénice A Benayoun, Lara J Monteiro, Helma DC Schwenen, Lars Grontved, Elizabeth Wederell, Susanne Mandrup, Reiner A Veitia et al. Genome Biology 2012, 13:R24 (29 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

A high quality compendium of transcription factor data that allows researchers to add new data via a peer-review system

18.

Research   Open Access

Genome-wide analysis of plant nat-siRNAs reveals insights into their distribution, biogenesis and function

Xiaoming Zhang, Jing Xia, Yifan E Lii, Blanca E Barrera-Figueroa, Xuefeng Zhou, Shang Gao, Lu Lu, Dongdong Niu, Zheng Chen, Christy Leung, Timothy Wong, Huiming Zhang, Jianhua Guo, Yi Li, Renyi Liu, Wanqi Liang, Jian-Kang Zhu, Weixiong Zhang, Hailing Jin Genome Biology 2012, 13:R20 (22 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In Arabidopsis and rice, natural antisense transcripts are processed into siRNAs by DCL1 and DCL3

19.

Research   Open Access

Ultrastructure of book gill development in embryos and first instars of the horseshoe crab Limulus polyphemus L. (Chelicerata, Xiphosura)

Roger D Farley Frontiers in Zoology 2012, 9:4 (21 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

Research article   Open Access

M cell targeting by a Claudin 4 targeting peptide can enhance mucosal IgA responses

David D Lo, Jun Ling, A Holly Eckelhoefer BMC Biotechnology 2012, 12:7 (13 March 2012)

Abstract | Full text | PDF | PubMed

21.

Software   Open Access Highly Accessed

ParentChecker: a computer program for automated inference of missing parental genotype calls and linkage phase correction

Zhiqiu Hu, Jeffrey D Ehlers, Philip A Roberts, Timothy J Close, Mitchell R Lucas, Steve Wanamaker, Shizhong Xu BMC Genetics 2012, 13:9 (23 February 2012)

Abstract | Full text | PDF | PubMed

22.

Research article   Open Access Highly Accessed

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties

Aliana López de Victoria, Chris A Kieslich, Apostolos K Rizos, Elias Krambovitis, Dimitrios Morikis BMC Biophysics 2012, 5:3 (7 February 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The spatial distributions of electrostatic potentials and charges in the V3 loop of HIV-1 protein gp120 may be responsible for both long- and short-range interactions with co-receptors, ultimately affecting viral entry into cells

23.

Research article   Open Access

Bilateral enucleation alters gene expression and intraneocortical connections in the mouse

Catherine A Dye, Charles W Abbott, Kelly J Huffman Neural Development 2012, 7:5 (30 January 2012)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

High content live cell imaging for the discovery of new antimalarial marine natural products

Serena Cervantes, Paige E Stout, Jacques Prudhomme, Sebastian Engel, Matthew Bruton, Michael Cervantes, David Carter, Young Tae-Chang, Mark E Hay, William Aalbersberg, Julia Kubanek, Karine G Le Roch BMC Infectious Diseases 2012, 12:1 (3 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Research article   Open Access

The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs

Peter Arensburger, Robert H Hice, Jennifer A Wright, Nancy L Craig, Peter W Atkinson BMC Genomics 2011, 12:606 (15 December 2011)

Abstract | Full text | PDF | PubMed

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