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101.

Research   Open Access

Personal endotoxin exposure in a panel study of school children with asthma

Ralph J Delfino, Norbert Staimer, Thomas Tjoa Environmental Health 2011, 10:69 (2 August 2011)

Abstract | Full text | PDF | PubMed | F1000 Medicine | F1000 Biology

102.

Research   Open Access

The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease

Hayk Davtyan, Anahit Ghochikyan, Richard Cadagan, Dmitriy Zamarin, Irina Petrushina, Nina Movsesyan, Luis Martinez-Sobrido, Randy A Albrecht, Adolfo García-Sastre, Michael G Agadjanyan Journal of Translational Medicine 2011, 9:127 (1 August 2011)

Abstract | Full text | PDF | PubMed

103.

Software   Open Access Highly Accessed

Applications of the pipeline environment for visual informatics and genomics computations

Ivo D Dinov, Federica Torri, Fabio Macciardi, Petros Petrosyan, Zhizhong Liu, Alen Zamanyan, Paul Eggert, Jonathan Pierce, Alex Genco, James A Knowles, Andrew P Clark, John D Van Horn, Joseph Ames, Carl Kesselman, Arthur W Toga BMC Bioinformatics 2011, 12:304 (26 July 2011)

Abstract | Full text | PDF | PubMed | 1 comment

104.

Keynote lecture presentation   Open Access

Functional network connectivity of the control and epileptic hippocampus

Ivan Soltesz BMC Neuroscience 2011, 12(Suppl 1):K1 (18 July 2011)

Full text | PDF

105.

Research   Open Access Highly Accessed

Characterization of Kupffer cells in livers of developing mice

Bryan G Lopez, Monica S Tsai, Janie L Baratta, Kenneth J Longmuir, Richard T Robertson Comparative Hepatology 2011, 10:2 (12 July 2011)

Abstract | Full text | PDF | PubMed

106.

Research   Open Access

Predation efficiency of Anopheles gambiae larvae by aquatic predators in western Kenya highlands

Eliningaya J Kweka, Guofa Zhou, Thomas M Gilbreath, Yaw Afrane, Mramba Nyindo, Andrew K Githeko, Guiyun Yan Parasites & Vectors 2011, 4:128 (5 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This is the first study reporting the predation efficiency of five locally available predators in western Kenya highlands against malaria vectors, Anopheles gambiae s.s. Image: Semi natural habitat with refugia used for predation experiments.

107.

Commentary   Open Access Highly Accessed

Robustness and fault tolerance make brains harder to study

Shyam Srinivasan, Charles F Stevens BMC Biology 2011, 9:46 (29 June 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A method commonly used to infer functional connectivity in neural circuits, Granger causality, has been put to the test on the well-defined crab pyloric network by Eve Marder and colleagues in a paper in Neural Systems and Circuits. Commenting in BMC Biology, Charles Stevens and Shyam Srinivasan posit that the need for nervous systems to be robust and fault tolerant makes it inevitable that inferential techniques of this kind will be error-prone.

108.

Research   Open Access

Enjoyment of exercise moderates the impact of a school-based physical activity intervention

Margaret Schneider, Dan M Cooper International Journal of Behavioral Nutrition and Physical Activity 2011, 8:64 (20 June 2011)

Abstract | Full text | PDF | PubMed

109.

Original research   Open Access Highly Accessed

Evaluation of 18F-nifene binding to α4β2 nicotinic receptors in the rat brain using microPET imaging

Ritu Kant, Cristian C Constantinescu, Puja Parekh, Suresh K Pandey, Min-Liang Pan, Balu Easwaramoorthy, Jogeshwar Mukherjee EJNMMI Research 2011, 1:6 (20 June 2011)

Abstract | Full text | PDF

110.

Research   Open Access Highly Accessed

Insecticide-treated net (ITN) ownership, usage, and malaria transmission in the highlands of western Kenya

Harrysone E Atieli, Guofa Zhou, Yaw Afrane, Ming-Chieh Lee, Isaac Mwanzo, Andrew K Githeko, Guiyun Yan Parasites & Vectors 2011, 4:113 (18 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study highlights how, despite high mosquito bed-net ownership recorded in most malaria risk regions, in practice, only half of them are actually used to provide protection against vector bites. Image: Properly hung mosquito bed-net.

111.

Research   Open Access

Evaluation of two methods of estimating larval habitat productivity in western Kenya highlands

Eliningaya J Kweka, Guofa Zhou, Ming-Chieh Lee, Thomas M Gilbreath, Franklin Mosha, Stephen Munga, Andrew K Githeko, Guiyun Yan Parasites & Vectors 2011, 4:110 (17 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study compared the emergence trap and aerial sampler methods in estimating mosquito larvae productivity in different seasons and habitats in western Kenya highlands. Image: Emergence trap located in a swamp for sampling.

112.

Methodology   Open Access

Estimating equations for biomarker based exposure estimation under non-steady-state conditions

Scott M Bartell, Wesley O Johnson Environmental Health 2011, 10:57 (13 June 2011)

Abstract | Full text | PDF | PubMed

113.

Research article   Open Access Highly Accessed

A conserved juxtacrine signal regulates synaptic partner recognition in Caenorhabditis elegans

Joori Park, Philip Knezevich, William Wung, Shanté O'Hanlon, Akshi Goyal, Kelli Benedetti, Benjamin Barsi-Rhyne, Mekala Raman, Natalyn Mock, Martina Bremer, Miri VanHoven Neural Development 2011, 6:28 (10 June 2011)

Abstract | Full text | PDF | PubMed

114.

Short report   Open Access Highly Accessed

An XMRV Derived Retroviral Vector as a Tool for Gene Transfer

Daniel Cervantes-Garcia, Augusto Rojas-Martinez, David Camerini Virology Journal 2011, 8:284 (8 June 2011)

Abstract | Full text | PDF | PubMed

115.

Research   Open Access

Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections

Paul H Smith, Jonathan M Mwangi, Yaw A Afrane, Guiyun Yan, Darren J Obbard, Lisa C Ranford-Cartwright, Tom J Little Malaria Journal 2011, 10:156 (8 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Insects lack a homologue of the vertebrate adaptive immune system, but different mechanisms, such as alternatively spliced Dscam, may exist for the detection of diverse antigenic patterns. The Dscam expression repertoire seems to differ when exposed to bacteria, Plasmodium berghei and P. falciparum.

116.

Comment   Open Access Highly Accessed

The individuality of stem cells

Arthur D Lander BMC Biology 2011, 9:40 (7 June 2011)

Full text | PDF | PubMed |  Editor’s summary

Arthur Lander reflects on how current assumptions that stem cells divide asymmetrically and are programmed to produce the right differentiated cell types at the right times may fail to acknowledge a fundamental contribution of stem cell individuality.

117.

Research   Open Access

Identification of malaria transmission and epidemic hotspots in the western Kenya highlands: its application to malaria epidemic prediction

Christine L Wanjala, John Waitumbi, Guofa Zhou, Andrew K Githeko Parasites & Vectors 2011, 4:81 (19 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The project identified three ecosystems based on terrain and topography controlling drainage and subsequently the availability and stability of vector breeding habitats, malaria prevalence, immune response and epidemic risks. Image: Poorly drained U-shaped Emutete valley - one of the study sites

118.

Research   Open Access

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

Jason G Weinger, Celia F Brosnan, Olivier Loudig, Michael F Goldberg, Fernando Macian, Heather A Arnett, Anne L Prieto, Vladislav Tsiperson, Bridget Shafit-Zagardo Journal of Neuroinflammation 2011, 8:49 (15 May 2011)

Abstract | Full text | PDF | PubMed

119.

Research   Open Access

Effect of visual distraction and auditory feedback on patient effort during robot-assisted movement training after stroke

Riccardo Secoli, Marie-Helene Milot, Giulio Rosati, David J Reinkensmeyer Journal of NeuroEngineering and Rehabilitation 2011, 8:21 (23 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

120.

Research   Open Access

Environmental resources moderate the relationship between social support and school sports participation among adolescents: a cross-sectional analysis

Dan J Graham, Margaret Schneider, Sally S Dickerson International Journal of Behavioral Nutrition and Physical Activity 2011, 8:34 (18 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

121.

Methodology article   Open Access Highly Accessed

SNP-based pathway enrichment analysis for genome-wide association studies

Lingjie Weng, Fabio Macciardi, Aravind Subramanian, Guia Guffanti, Steven G Potkin, Zhaoxia Yu, Xiaohui Xie BMC Bioinformatics 2011, 12:99 (15 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

122.

Research article   Open Access

The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort

Eunjung Lee, Fredrick Schumacher, Juan Pablo Lewinger, Susan L Neuhausen, Hoda Anton-Culver, Pamela L Horn-Ross, Katherine D Henderson, Argyrios Ziogas, David Van Den Berg, Leslie Bernstein, Giske Ursin Breast Cancer Research 2011, 13:R37 (1 April 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Polymorphisms of a solute carrier organic anion transporter gene, SLCO1B1, are associated with breast cancer risk in postmenopausal women, particularly among combined estrogen-progestin therapy users.

123.

Meeting report   Open Access

At the frontiers of surgery: review

Tahwinder Upile, Waseem K Jerjes, Henricus J Sterenborg, Brian J Wong, Adel K El-Naggar, Justus F Ilgner, Ann Sandison, Max J Witjes, Merrill A Biel, Robert van Veen, Zaid Hamdoon, Ann Gillenwater, Charles A Mosse, Dominic J Robinson, Christian S Betz, Herbert Stepp, Lina Bolotine, Gordon McKenzie, Hugh Barr, Zhongping Chen, Kristian Berg, Anil K D'Cruz, Holger Sudhoff, Nicholas Stone, Catherine Kendall, Sheila Fisher, Alexander J MacRobert, Andreas Leunig, Malini Olivo, Rebecca Richards-Kortum et al. Head & Neck Oncology 2011, 3:7 (9 February 2011)

Abstract | Full text | PDF | PubMed

124.

Opinion   Open Access

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

Blanca-Liliana Perlaza, Jean-Pierre Sauzet, Karima Brahimi, Lbachir BenMohamed, Pierre Druilhe Malaria Journal 2011, 10:27 (8 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Evidence that has been gathered in vitro and in vivo, in higher primates and in humans, is reviewed here, emphasizing the significant role of IFN-γ, either as a critical immune mediator or at least as a valuable surrogate marker of protection

125.

Research   Open Access Highly Accessed

The effects of the HEALTHY study intervention on middle school student dietary intakes

Anna Siega-Riz, Laurie El Ghormli, Connie Mobley, Bonnie Gillis, Diane Stadler, Jill Hartstein, Stella L Volpe, Amy Virus, Jessica Bridgman, International Journal of Behavioral Nutrition and Physical Activity 2011, 8:7 (4 February 2011)

Abstract | Full text | PDF | PubMed

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