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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at University of California, Irvine

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51.

Research   Open Access Highly Accessed

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

David H Cribbs, Nicole C Berchtold, Victoria Perreau, Paul D Coleman, Joseph Rogers, Andrea J Tenner, Carl W Cotman Journal of Neuroinflammation 2012, 9:179 (23 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

52.

Research   Open Access Highly Accessed

Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal

Koen K A Van Rompay, Kristin A Trott, Kartika Jayashankar, Yongzhi Geng, Celia C LaBranche, Jeffrey A Johnson, Gary Landucci, Jonathan Lipscomb, Ross P Tarara, Don R Canfield, Walid Heneine, Donald N Forthal, David Montefiori, Kristina Abel Retrovirology 2012, 9:57 (17 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Under certain conditions (i.e., prolonged antiviral therapy initiated early after infection; viral mutants with reduced drug susceptibility) a virus-host balance characterized by strong immunologic control of virus replication can be achieved.

53.

Research article   Open Access

DNA variation in the phenotypically-diverse brown alga Saccharina japonica

Evgeniy S Balakirev, Tatiana N Krupnova, Francisco J Ayala BMC Plant Biology 2012, 12:108 (11 July 2012)

Abstract | Full text | PDF | PubMed

54.

Research   Open Access

Modeling personal particle-bound polycyclic aromatic hydrocarbon (pb-pah) exposure in human subjects in Southern California

Jun Wu, Thomas Tjoa, Lianfa Li, Guillermo Jaimes, Ralph J Delfino Environmental Health 2012, 11:47 (11 July 2012)

Abstract | Full text | PDF | PubMed

55.

Review   Open Access Highly Accessed

Complement activation in the injured central nervous system: another dual-edged sword?

Faith H Brennan, Aileen J Anderson, Stephen M Taylor, Trent M Woodruff, Marc J Ruitenberg Journal of Neuroinflammation 2012, 9:137 (21 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

56.

Poster presentation   Open Access

P02.73. Optimal healing environment in a continuing care retirement community: a feasibility study

W Najm, R Chez, W Jonas, W Zhang BMC Complementary and Alternative Medicine 2012, 12(Suppl 1):P129 (12 June 2012)

Full text | PDF

57.

Poster presentation   Open Access

P02.07. A study to assess the validity of applied kinesiology (AK) as a diagnostic tool and as a nonlocal proximity effect

S Schwartz, J Utts, S Spottiswoode, C Shade, L Tully, W Morris, G Nachman BMC Complementary and Alternative Medicine 2012, 12(Suppl 1):P63 (12 June 2012)

Full text | PDF

58.

Review   Open Access Highly Accessed

A unified phylogeny-based nomenclature for histone variants

Paul B Talbert, Kami Ahmad, Geneviève Almouzni, Juan Ausió, Frederic Berger, Prem L Bhalla, William M Bonner, W Cande, Brian P Chadwick, Simon W L Chan, George A M Cross, Liwang Cui, Stefan I Dimitrov, Detlef Doenecke, José M Eirin-López, Martin A Gorovsky, Sandra B Hake, Barbara A Hamkalo, Sarah Holec, Steven E Jacobsen, Kinga Kamieniarz, Saadi Khochbin, Andreas G Ladurner, David Landsman, John A Latham, Benjamin Loppin, Harmit S Malik, William F Marzluff, John R Pehrson, Jan Postberg et al. Epigenetics & Chromatin 2012, 5:7 (31 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In response to an urgent need to rationalize the current schemes for naming histone variants, researchers from over 30 institutions worldwide have developed consistent but flexible naming rules that are informative and database-searchable.

59.

Research article   Open Access

High-throughput comparison of gene fitness among related bacteria

Rocio Canals, Xiao-Qin Xia, Catrina Fronick, Sandra W Clifton, Brian MM Ahmer, Helene L Andrews-Polymenis, Steffen Porwollik, Michael McClelland BMC Genomics 2012, 13:212 (30 May 2012)

Abstract | Full text | PDF | PubMed

60.

Research   Open Access

Prokineticin 2 potentiates acid-sensing ion channel activity in rat dorsal root ganglion neurons

Chun-Yu Qiu, Yu-Qiang Liu, Fang Qiu, Jiliang Wu, Qun-Yong Zhou, Wang-Ping Hu Journal of Neuroinflammation 2012, 9:108 (29 May 2012)

Abstract | Full text | PDF | PubMed

61.

Research article   Open Access Highly Accessed

Children eat their school lunch too quickly: an exploratory study of the effect on food intake

Modjtaba Zandian, Ioannis Ioakimidis, Jakob Bergström, Ulf Brodin, Cecilia Bergh, Michael Leon, Julian Shield, Per Södersten BMC Public Health 2012, 12:351 (14 May 2012)

Abstract | Full text | PDF | PubMed

62.

Research article   Open Access Highly Accessed

Molecular evolution of pentatricopeptide repeat genes reveals truncation in species lacking an editing target and structural domains under distinct selective pressures

Michael L Hayes, Karolyn Giang, R Mulligan BMC Evolutionary Biology 2012, 12:66 (14 May 2012)

Abstract | Full text | PDF | PubMed

63.

Research   Open Access

Increased burst size in multiply infected cells can alter basic virus dynamics

Kara W Cummings, David N Levy, Dominik Wodarz Biology Direct 2012, 7:16 (8 May 2012)

Abstract | Full text | PDF | PubMed

64.

Research article   Open Access

Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster

Man-Sun Kim, Jeong-Rae Kim, Dongsan Kim, Arthur D Lander, Kwang-Hyun Cho BMC Systems Biology 2012, 6:31 (1 May 2012)

Abstract | Full text | PDF | PubMed

65.

Review   Free Highly Accessed

Examining the mechanisms that link β-amyloid and α-synuclein pathologies

Samuel E Marsh, Mathew Blurton-Jones Alzheimer's Research & Therapy 2012, 4:11 (30 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Marsh and Blurton-Jones review evidence suggesting β-amyloid (Aβ) and α-synuclein (α-syn) interact synergistically to enhance aggregation and accelerate cognitive decline, and propose potential mechanistic links between Aβ and α-syn pathologies.

66.

Commentary   Open Access

Major trends in mobility technology research and development: Overview of the results of the NSF-WTEC European study

David J Reinkensmeyer, Paolo Bonato, Michael L Boninger, Leighton Chan, Rachel E Cowan, Benjamin J Fregly, Mary M Rodgers Journal of NeuroEngineering and Rehabilitation 2012, 9:22 (20 April 2012)

Abstract | Full text | PDF | PubMed

67.

Review   Open Access Highly Accessed

Recent trends in assistive technology for mobility

Rachel E Cowan, Benjamin J Fregly, Michael L Boninger, Leighton Chan, Mary M Rodgers, David J Reinkensmeyer Journal of NeuroEngineering and Rehabilitation 2012, 9:20 (20 April 2012)

Abstract | Full text | PDF | PubMed

68.

Research article   Open Access

An optimally evolved connective ratio of neural networks that maximizes the occurrence of synchronized bursting behavior

Chao-Yi Dong, Kwang-Hyun Cho BMC Systems Biology 2012, 6:23 (31 March 2012)

Abstract | Full text | PDF | PubMed

69.

Review   Open Access

Personalized neuromusculoskeletal modeling to improve treatment of mobility impairments: a perspective from European research sites

Benjamin J Fregly, Michael L Boninger, David J Reinkensmeyer Journal of NeuroEngineering and Rehabilitation 2012, 9:18 (30 March 2012)

Abstract | Full text | PDF | PubMed

70.

Commentary   Open Access Highly Accessed

Technologies and combination therapies for enhancing movement training for people with a disability

David J Reinkensmeyer, Michael L Boninger Journal of NeuroEngineering and Rehabilitation 2012, 9:17 (30 March 2012)

Abstract | Full text | PDF | PubMed

71.

Research article   Open Access Highly Accessed

Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice

Zhizhang Dong, Juan Li, Yunxia Leng, Xuerong Sun, Huiling Hu, Yuan He, Zhiqun Tan, Jian Ge BMC Neuroscience 2012, 13:34 (24 March 2012)

Abstract | Full text | PDF | PubMed

72.

Research   Open Access Highly Accessed

Accelerated hypofractionated radiation therapy compared to conventionally fractionated radiation therapy for the treatment of inoperable non-small cell lung cancer

Arya Amini, Steven H Lin, Caimiao Wei, Pamela Allen, James D Cox, Ritsuko Komaki Radiation Oncology 2012, 7:33 (15 March 2012)

Abstract | Full text | PDF | PubMed

73.

Forum   Open Access Highly Accessed

What does the concept of the stem cell niche really mean today?

Arthur D Lander, Judith Kimble, Hans Clevers, Elaine Fuchs, Didier Montarras, Margaret Buckingham, Anne L Calof, Andreas Trumpp, Thordur Oskarsson BMC Biology 2012, 10:19 (9 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

How do current researchers view the stem cell niche? Eight experts from different fields provide their perspective, and ask how stem cells evolve in such an environment, launching a new Forum article type within the cross-journal collection on stem cells.

74.

Research article   Open Access

Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands

Kingsley Badu, Yaw Afrane, John Larbi, Virginia Stewart, John Waitumbi, Evelina Angov, John M Ong'echa, Douglas J Perkins, Guofa Zhou, Andrew Githeko, Guiyun Yan BMC Infectious Diseases 2012, 12:50 (1 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

75.

Review   Open Access Highly Accessed

Point specificity in acupuncture

Emma M Choi, Fang Jiang, John C Longhurst Chinese Medicine 2012, 7:4 (28 February 2012)

Abstract | Full text | PDF | PubMed

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