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301.

Research article   Open Access

SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis

Clare C Constantine, Lyle C Gurrin, Christine E McLaren, Melanie Bahlo, Gregory J Anderson, Chris D Vulpe, Susan M Forrest, Katrina J Allen, Dorota M Gertig, BMC Medical Genetics 2008, 9:18 (20 March 2008)

Abstract | Full text | PDF | PubMed

302.

Research article   Open Access Highly Accessed

Evolution of gastropod mitochondrial genome arrangements

Cristina Grande, José Templado, Rafael Zardoya BMC Evolutionary Biology 2008, 8:61 (26 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

303.

Research article   Open Access Highly Accessed

Post-Messinian evolutionary relationships across the Sicilian channel: Mitochondrial and nuclear markers link a new green toad from Sicily to African relatives

Matthias Stöck, Alessandra Sicilia, Natalia M Belfiore, David Buckley, Sabrina Lo Brutto, Mario Lo Valvo, Marco Arculeo BMC Evolutionary Biology 2008, 8:56 (23 February 2008)

Abstract | Full text | PDF | PubMed | 1 comment

304.

Research   Open Access

Comparative hybridization reveals extensive genome variation in the AIDS-associated pathogen Cryptococcus neoformans

Guanggan Hu, Iris Liu, Anita Sham, Jason E Stajich, Fred S Dietrich, James W Kronstad Genome Biology 2008, 9:R41 (22 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Extensive genome variation in the AIDS-associated pathogen Cryptococcus neoformans is revealed through comparative genome hybridization between strains of different mating type, molecular subtype and ploidy.

305.

Research   Open Access

Mechanisms of intron gain and loss in Cryptococcus

Thomas J Sharpton, Daniel E Neafsey, James E Galagan, John W Taylor Genome Biology 2008, 9:R24 (30 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Comparison of five relatively closely related yeast Cryptococcus genomes suggests that recombination causes internal intron loss and that DNA repeat expansion can create new introns in a population.

306.

Research article   Open Access

Comparison of pulmonary and extrapulmonary tuberculosis in Nepal- a hospital-based retrospective study

Chandrashekhar T Sreeramareddy, Kishore V Panduru, Sharat C Verma, Hari S Joshi, Michael N Bates BMC Infectious Diseases 2008, 8:8 (24 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

307.

Research   Open Access Highly Accessed

Horizontal gene transfer and the evolution of transcriptional regulation in Escherichia coli

Morgan N Price, Paramvir S Dehal, Adam P Arkin Genome Biology 2008, 9:R4 (7 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Most Escherichia coli transcription factors have paralogs, but these usually arose by horizontal gene transfer rather than by duplication within the E. coli lineage, as previously believed.

308.

Proceedings   Open Access

Conditional genotype analysis: detecting secondary disease loci in linkage disequilibrium with a primary disease locus

Glenys Thomson, Ana Valdes BMC Proceedings 2007, 1(Suppl 1):S163 (18 December 2007)

Abstract | Full text | PDF | PubMed

309.

Research article   Open Access Highly Accessed

Systematics and plastid genome evolution of the cryptically photosynthetic parasitic plant genus Cuscuta (Convolvulaceae)

Joel R McNeal, Kathiravetpilla Arumugunathan, Jennifer V Kuehl, Jeffrey L Boore, Claude W dePamphilis BMC Biology 2007, 5:55 (13 December 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The parasitic plant genus Cuscuta has undergone complex patterns of evolution according to new evidence from DNA sequence data, therefore classifying this unusual group based on morphological or ecological characteristics alone is misleading.

310.

Research Article   Open Access

Anthropocentric Video Segmentation for Lecture Webcasts

Gerald Friedland, Raul Rojas EURASIP Journal on Image and Video Processing 2007, 2008:195743 (12 December 2007)

Abstract | Full text | PDF

311.

Research article   Open Access Highly Accessed

Analysis of gene expression during neurite outgrowth and regeneration

Moriah L Szpara, Karen Vranizan, Yu Tai, Corey S Goodman, Terence P Speed, John Ngai BMC Neuroscience 2007, 8:100 (23 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

312.

Research Article   Open Access

Energy-Efficient Bandwidth Allocation for Multiuser Scalable Video Streaming over WLAN

Xin Ji, Sofie Pollin, Gauthier Lafruit, Iole Moccagatta, Antoine Dejonghe , Francky Catthoor EURASIP Journal on Wireless Communications and Networking 2008, 2008:219570 (5 November 2007)

Abstract | Full text | PDF

313.

Research   Open Access Highly Accessed

The effect of HIV on morbidity and mortality in children with severe malarial anaemia

Samuel Malamba, Wolfgang Hladik, Arthur Reingold, Flora Banage, Willi McFarland, George Rutherford, Derrick Mimbe, Esau Nzaro, Robert Downing, Jonathan Mermin Malaria Journal 2007, 6:143 (31 October 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study demonstrates that HIV-infected children were approximately three times more likely to die within seven days of a symptomatic malaria episode than HIV-uninfected children, and had more frequent re-admissions due to malaria within 28 days.

314.

Research   Open Access Highly Accessed

Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study

Gladys Block, Christopher D Jensen, Edward P Norkus, Tapashi B Dalvi, Les G Wong, Jamie F McManus, Mark L Hudes Nutrition Journal 2007, 6:30 (24 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

315.

Research article   Open Access Highly Accessed

Complete plastid genome sequences suggest strong selection for retention of photosynthetic genes in the parasitic plant genus Cuscuta

Joel R McNeal, Jennifer V Kuehl, Jeffrey L Boore, Claude W de Pamphilis BMC Plant Biology 2007, 7:57 (24 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Parasitic Cuscuta species have surprisingly retained genes involved in photosynthesis, unlike the parasitic plant Epifagus which lost these genes, suggesting that selection on RuBisCo and photosystems is the primary reason for maintaining the plastid genome in Cuscuta.

316.

Research article   Open Access

Effectiveness of the polysaccharide pneumococcal vaccine among HIV-infected persons in Brazil: a case control study

Maria Veras, Wayne TA Enanoria, Euclides A Castilho, Arthur L Reingold BMC Infectious Diseases 2007, 7:119 (23 October 2007)

Abstract | Full text | PDF | PubMed

317.

Research   Open Access Highly Accessed

Comparative genomic analysis of fungal genomes reveals intron-rich ancestors

Jason E Stajich, Fred S Dietrich, Scott W Roy Genome Biology 2007, 8:R223 (19 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Analysis of intron gain and loss in fungal genomes provides support for an intron-rich fungus-animal ancestor.

318.

Software   Open Access

Strainer: software for analysis of population variation in community genomic datasets

John M Eppley, Gene W Tyson, Wayne M Getz, Jillian F Banfield BMC Bioinformatics 2007, 8:398 (17 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

319.

Research article   Open Access

Longitudinal, population-based study of racial/ethnic differences in colorectal cancer survival: impact of neighborhood socioeconomic status, treatment and comorbidity

Scarlett Gomez, Cynthia D O'Malley, Antoinette Stroup, Sarah J Shema, William A Satariano BMC Cancer 2007, 7:193 (16 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

320.

Research article   Open Access

Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p

Bernhard Suter, Oxana Pogoutse, Xinghua Guo, Nevan Krogan, Peter Lewis, Jack F Greenblatt, Jasper Rine, Andrew Emili BMC Biology 2007, 5:38 (19 September 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The yeast histone acetyltransferase Hat1p is involved in nuclear chromatin assembly, but also interacts with the origin recognition complex and with chromatin during S-phase, suggesting a new role for this histone acetyltransferase in DNA replication.

321.

Research article   Open Access Highly Accessed

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers

Christina Yau, Vita Fedele, Ritu Roydasgupta, Jane Fridlyand, Alan Hubbard, Joe W Gray, Karen Chew, Shanaz H Dairkee, Dan H Moore, Francesco Schittulli, Stefania Tommasi, Angelo Paradiso, Donna G Albertson, Christopher C Benz Breast Cancer Research 2007, 9:R59 (12 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Epigenetic transcriptome changes, more than genotypic variation, account for age-associated differences in the incidence and prognosis of sporadic hormone-dependant breast cancer, according to microarray study.

322.

Research article   Open Access Highly Accessed

The importance of comparative phylogeography in diagnosing introduced species: a lesson from the seal salamander, Desmognathus monticola

Ronald M Bonett, Kenneth H Kozak, David R Vieites, Alison Bare, Jessica A Wooten, Stanley E Trauth BMC Ecology 2007, 7:7 (7 September 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Isolated seal salamanders hundreds of kilometers from their native habitat share identical haplotypes with salamanders in the main population, revealing them to be an invader that threatens local species, rather than a relict that needs conserving.

323.

Research article   Open Access

Can family planning outreach bridge the urban-rural divide in Zambia?

Justin S White, Ilene S Speizer BMC Health Services Research 2007, 7:143 (5 September 2007)

Abstract | Full text | PDF | PubMed

324.

Research article   Open Access Highly Accessed

Global analysis of host response to induction of a latent bacteriophage

Robin E Osterhout, Israel A Figueroa, Jay D Keasling, Adam P Arkin BMC Microbiology 2007, 7:82 (31 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

325.

Commentary   Open Access

Measuring perinatal complications: methodologic issues related to gestational age

Aaron B Caughey BMC Pregnancy and Childbirth 2007, 7:18 (30 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

326.

Research article   Open Access Highly Accessed

Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach

Tiago R Magalhães, Jessica Palmer, Pavel Tomancak, Katherine S Pollard BMC Neuroscience 2007, 8:59 (31 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

327.

Research article   Open Access

Comparative mitochondrial genomics of snakes: extraordinary substitution rate dynamics and functionality of the duplicate control region

Zhi J Jiang, Todd A Castoe, Christopher C Austin, Frank T Burbrink, Matthew D Herron, Jimmy A McGuire, Christopher L Parkinson, David D Pollock BMC Evolutionary Biology 2007, 7:123 (26 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

328.

Research article   Open Access

Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis

Uffe Hellsten, Mustafa K Khokha, Timothy C Grammer, Richard M Harland, Paul Richardson, Daniel S Rokhsar BMC Biology 2007, 5:31 (25 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A doubling of the Xenopus laevis genome accelerated the evolution of over 2,000 gene pairs, and many of these duplicate pairs have substantially different expression levels and patterns corresponding to partially divergent roles or subfunctions.

329.

Research article   Open Access

Proteomic screen in the simple metazoan Hydra identifies 14-3-3 binding proteins implicated in cellular metabolism, cytoskeletal organisation and Ca2+ signalling

Barbara Pauly, Margherita Lasi, Carol MacKintosh, Nick Morrice, Axel Imhof, Jörg Regula, Stephen Rudd, Charles N David, Angelika Böttger BMC Cell Biology 2007, 8:31 (25 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

330.

Oral presentation   Open Access

Molecular steps in sGC activation

Elizabeth M Boon, Stephen PL Cary, Shirley H Huang, Jonathan A Winger, Emily R Derbyshire, Mark S Price, William K Erbil, Michael A Marletta BMC Pharmacology 2007, 7(Suppl 1):S27 (25 July 2007)

Full text | PDF

331.

Research   Open Access Highly Accessed

Global analysis of patterns of gene expression during Drosophila embryogenesis

Pavel Tomancak, Benjamin P Berman, Amy Beaton, Richard Weiszmann, Elaine Kwan, Volker Hartenstein, Susan E Celniker, Gerald M Rubin Genome Biology 2007, 8:R145 (23 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Embryonic expression patterns for 6,003 (44%) of the 13,659 protein-coding genes identified in the Drosophila melanogaster genome were documented, of which 40% show tissue-restricted expression.

332.

Research article   Open Access Highly Accessed

Pbx homeodomain proteins pattern both the zebrafish retina and tectum

Curtis R French, Timothy Erickson, Davon Callander, Karyn M Berry, Ron Koss, Daniel W Hagey, Jennifer Stout, Katrin Wuennenberg-Stapleton, John Ngai, Cecilia B Moens, Andrew J Waskiewicz BMC Developmental Biology 2007, 7:85 (16 July 2007)

Abstract | Full text | PDF | PubMed

333.

Research   Open Access

Automatic image analysis for gene expression patterns of fly embryos

Hanchuan Peng, Fuhui Long, Jie Zhou, Garmay Leung, Michael B Eisen, Eugene W Myers BMC Cell Biology 2007, 8(Suppl 1):S7 (10 July 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

334.

Research article   Open Access

Early prediction of median survival among a large AIDS surveillance cohort

Wayne TA Enanoria, Alan E Hubbard, Mark J van der Laan, Mi Chen, Juan Ruiz, John M Colford BMC Public Health 2007, 7:127 (27 June 2007)

Abstract | Full text | PDF | PubMed

335.

Research   Open Access Highly Accessed

Spatial distribution of traffic induced noise exposures in a US city: an analytic tool for assessing the health impacts of urban planning decisions

Edmund Seto, Ashley Holt, Tom Rivard, Rajiv Bhatia International Journal of Health Geographics 2007, 6:24 (21 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

336.

Research article   Open Access

Comparative chloroplast genomics: analyses including new sequences from the angiosperms Nuphar advena and Ranunculus macranthus

Linda A Raubeson, Rhiannon Peery, Timothy W Chumley, Chris Dziubek, H Matthew Fourcade, Jeffrey L Boore, Robert K Jansen BMC Genomics 2007, 8:174 (15 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

337.

Research   Open Access Highly Accessed

Global analyses of mRNA translational control during early Drosophila embryogenesis

Xiaoli Qin, Soyeon Ahn, Terence P Speed, Gerald M Rubin Genome Biology 2007, 8:R63 (22 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The polysomal profiles of over 15,000 transcripts during the first ten hours after egg laying have been determined.

338.

Research article   Open Access Highly Accessed

Analysis of epistatic interactions and fitness landscapes using a new geometric approach

Niko Beerenwinkel, Lior Pachter, Bernd Sturmfels, Santiago F Elena, Richard E Lenski BMC Evolutionary Biology 2007, 7:60 (13 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A new mathematical description of how multiple genetic mutations affect organism fitness considers previously unappreciated gene interactions to give a more complex picture of fitness landscapes than that depicted by average curvature or pairwise interaction distribution.

339.

Research article   Open Access Highly Accessed

Does vancomycin prescribing intervention affect vancomycin-resistant enterococcus infection and colonization in hospitals? A systematic review

Monique A de Bruin, Lee W Riley BMC Infectious Diseases 2007, 7:24 (10 April 2007)

Abstract | Full text | PDF | PubMed

340.

Correction   Open Access

Correction: PCR and dissection as tools to monitor filarial infection of Aedes polynesiensis mosquitoes in French Polynesia

Catherine Plichart, Sandra J Laney, Yves Sechan, Neil Davies, Anne-Marie Legrand Filaria Journal 2007, 6:5 (30 March 2007)

Abstract | Full text | PDF

341.

Research article   Open Access

Effect of solution saturation state and temperature on diopside dissolution

Suvasis Dixit, Susan A Carroll Geochemical Transactions 2007, 8:3 (26 March 2007)

Abstract | Full text | PDF | PubMed

342.

Research   Open Access Highly Accessed

A comparison of mantle versus involved-field radiotherapy for Hodgkin's lymphoma: reduction in normal tissue dose and second cancer risk

Eng-Siew Koh, Tu Tran, Mostafa Heydarian, Rainer K Sachs, Richard W Tsang, David J Brenner, Melania Pintilie, Tony Xu, June Chung, Narinder Paul, David C Hodgson Radiation Oncology 2007, 2:13 (15 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

343.

Debate   Open Access Highly Accessed

Slum health: Diseases of neglected populations

Lee W Riley, Albert I Ko, Alon Unger, Mitermayer G Reis BMC International Health and Human Rights 2007, 7:2 (7 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

344.

Research article   Open Access

A phylogenomic analysis of the Actinomycetales mce operons

Nicola Casali, Lee W Riley BMC Genomics 2007, 8:60 (26 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

345.

Research article   Open Access

Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis to nitric oxide correlates with disease severity in Tegumentary Leishmaniasis

Angela Giudice, Ilza Camada, Paulo TG Leopoldo, Júlia MB Pereira, Lee W Riley, Mary E Wilson, John L Ho, Amelia de Jesus, Edgar M Carvalho, Roque P Almeida BMC Infectious Diseases 2007, 7:7 (22 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

346.

Research article   Open Access

Dynamics of in silico leukocyte rolling, activation, and adhesion

Jonathan Tang, Klaus F Ley, C Anthony Hunt BMC Systems Biology 2007, 1:14 (19 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

347.

Research   Open Access

FlowerPower: clustering proteins into domain architecture classes for phylogenomic inference of protein function

Nandini Krishnamurthy, Duncan Brown, Kimmen Sjölander BMC Evolutionary Biology 2007, 7(Suppl 1):S12 (8 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

348.

Software   Open Access Highly Accessed

GEVALT: An integrated software tool for genotype analysis

Ofir Davidovich, Gad Kimmel, Ron Shamir BMC Bioinformatics 2007, 8:36 (1 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

349.

Research article   Open Access Highly Accessed

Measuring similarities between gene expression profiles through new data transformations

Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-Beum Lee, Lewis J Feldman, Haiyan Huang BMC Bioinformatics 2007, 8:29 (27 January 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

350.

Research article   Open Access

Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models

Lakshmanaswamy Rajkumar, Frances S Kittrell, Raphael C Guzman, Powel H Brown, Satyabrata Nandi, Daniel Medina Breast Cancer Research 2007, 9:R12 (26 January 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

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