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51.

Research article   Open Access

Treatment-independent miRNA signature in blood of wilms tumor patients

Jana Schmitt, Christina Backes, Nasenien Nourkami-Tutdibi, Petra Leidinger, Stephanie Deutscher, Markus Beier, Manfred Gessler, Norbert Graf, Hans-Peter Lenhof, Andreas Keller, Eckart Meese BMC Genomics 2012, 13:379 (7 August 2012)

Abstract | Full text | PDF | PubMed

52.

Methodology   Open Access

Methods of staining and visualization of sphingolipid enriched and non-enriched plasma membrane regions of Arabidopsis thaliana with fluorescent dyes and lipid analogues

Jörg O Blachutzik, Fatih Demir, Ines Kreuzer, Rainer Hedrich, Gregory S Harms Plant Methods 2012, 8:28 (6 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Lipid rafts are microdomains within the plasma membrane in which the lipids are more ordered than in the surrounding bilayer and they play an important role in processes such as signalling, membrane fluidity and protein trafficking. Staining methods for visualizing these lipid domains have in the past been developed almost exclusively for animal cells and tissues. Here the authors describe procedures they have developed and verified for the successful fluorescent staining of lipid domains in living leaf tissue and protoplasts.

53.

Research article   Open Access

Bioinformatic cis-element analyses performed in Arabidopsis and rice disclose bZIP- and MYB-related binding sites as potential AuxRE-coupling elements in auxin-mediated transcription

Kenneth W Berendzen, Christoph Weiste, Dierk Wanke, Joachim Kilian, Klaus Harter, Wolfgang Dröge-Laser BMC Plant Biology 2012, 12:125 (1 August 2012)

Abstract | Full text | PDF | PubMed

54.

Research   Open Access Highly Accessed

Diffusion-weighted MRI of bone marrow oedema, soft tissue oedema and synovitis in paediatric patients: feasibility and initial experience

Henning Neubauer, Laura Evangelista, Henner Morbach, Hermann Girschick, Martina Prelog, Herbert Köstler, Dietbert Hahn, Meinrad Beer Pediatric Rheumatology 2012, 10:20 (31 July 2012)

Abstract | Full text | PDF | PubMed

55.

Letter to the Editor   Open Access

GOLD or lower limit of normal definition? a letter and authors’ response

Philip Quanjer, Carlos A Fragoso, Martin R Miller, Gülmisal Güder, Stefan Störk, Arno W Hoes, Frans Rutten Respiratory Research 2012, 13:61 (26 July 2012)

Abstract | Full text | PDF | PubMed

56.

Research article   Open Access Highly Accessed

Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells

Andre F Steinert, Manuel Weissenberger, Manuela Kunz, Fabian Gilbert, Steven C Ghivizzani, Sascha Göbel, Franz Jakob, Ulrich Nöth, Maximilian Rudert Arthritis Research & Therapy 2012, 14:R168 (20 July 2012)

Abstract | Full text | PDF | PubMed

57.

Oral presentation   Open Access

Systemic juvenile idiopathic arthritis is associated with HLA-DRB1 in Europeans and Americans of European descent

Michael Ombrello, Elaine F Remmers, Alexei A Grom, Wendy Thomson, Alberto Martini, Marco Gattorno, Seza Ozen, Ahmet Gul, John F Bohnsack, Andrew S Zeft, Elizabeth D Mellins, Jane L Park, Claudio Len, Colleen Satorius, Ricardo AG Russo, Terri H Finkel, Rae SM Yeung, Rayfel Schneider, Sampath Prahalad, David N Glass, Roger C Allen, Nico Wulffraat, Pierre Quartier, Maria Odete E Hilario, Kevin Murray, Sheila Oliveira, Jordi Anton, Anne Hinks, Eleftheria Zeggini, Carl Langefeld, Susan Thompson, Jeffrey Chaitow, Justine Ellis, Davinder Singh, Andre Cavalvanti, Blanca Bica, Flavio Sztajnbok, Hakon Hakonarson, Katherine A Siminovitch, Kirsten Minden, Peter Haas, Tobias Schwarz, Daniel L Kastner, Patricia Woo et al. Pediatric Rheumatology 2012, 10(Suppl 1):A6 (13 July 2012)

Full text | PDF

58.

Research article   Open Access Highly Accessed

Prospective evaluation of quality of life effects in patients undergoing palliative radiotherapy for brain metastases

Diana Steinmann, Yvonne Paelecke-Habermann, Hans Geinitz, Raimund Aschoff, Anja Bayerl, Tobias Bölling, Elisabeth Bosch, Frank Bruns, Ute Eichenseder-Seiss, Johanna Gerstein, Nadine Gharbi, Juliane Hagg, Matthias Hipp, Irmgard Kleff, Axel Müller, Christof Schäfer, Ursula Schleicher, Susanne Sehlen, Marilena Theodorou, Hans-Joachim Wypior, Franz Zehentmayr, Birgitt van Oorschot, Dirk Vordermark BMC Cancer 2012, 12:283 (10 July 2012)

Abstract | Full text | PDF | PubMed

59.

Review   Open Access

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

Edgar Serfling, Andris Avots, Stefan Klein-Hessling, Ronald Rudolf, Martin Vaeth, Friederike Berberich-Siebelt Cell Communication and Signaling 2012, 10:16 (5 July 2012)

Abstract | Full text | PDF | PubMed

60.

Study protocol   Open Access Highly Accessed

Prevalence of mental disorders, psychosocial distress and need for psychosocial support in cancer patients – study protocol of an epidemiological multi-center study

Anja Mehnert, Uwe Koch, Holger Schulz, Karl Wegscheider, Joachim Weis, Hermann Faller, Monika Keller, Elmar Brähler, Martin Härter BMC Psychiatry 2012, 12:70 (2 July 2012)

Abstract | Full text | PDF | PubMed

61.

Research article   Open Access

A multi-center, prospective, open-label, 8-week study of certoparin for anticoagulation during maintenance hemodialysis – the membrane study

Oliver Dorsch, Detlef H Krieter, Horst-Dieter Lemke, Stefan Fischer, Nima Melzer, Christian Sieder, Peter Bramlage, Job Harenberg BMC Nephrology 2012, 13:50 (28 June 2012)

Abstract | Full text | PDF | PubMed

62.

Research   Open Access

Radiotherapy alone for stage I-III low grade follicular lymphoma: long-term outcome and comparison of extended field and total nodal irradiation

Matthias Guckenberger, Nikolaus Alexandrow, Michael Flentje Radiation Oncology 2012, 7:103 (24 June 2012)

Abstract | Full text | PDF | PubMed

63.

Research   Open Access

Combination of peptide receptor radionuclide therapy with fractionated external beam radiotherapy for treatment of advanced symptomatic meningioma

Michael C Kreissl, Heribert Hänscheid, Mario Löhr, Frederik A Verburg, Markus Schiller, Michael Lassmann, Christoph Reiners, Samuel S Samnick, Andreas K Buck, Michael Flentje, Reinhart A Sweeney Radiation Oncology 2012, 7:99 (21 June 2012)

Abstract | Full text | PDF | PubMed

64.

Methodology article   Open Access

Integrated pathway modules using time-course metabolic profiles and EST data from Milnesium tardigradum

Daniela Beisser, Markus A Grohme, Joachim Kopka, Marcus Frohme, Ralph O Schill, Steffen Hengherr, Thomas Dandekar, Gunnar W Klau, Marcus Dittrich, Tobias Müller BMC Systems Biology 2012, 6:72 (19 June 2012)

Abstract | Full text | PDF | PubMed

65.

Short Report   Open Access

Clinical characteristics of pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Northern Bavaria, Germany

Anna Wieching, Jasmin Benser, Christina Kohlhauser-Vollmuth, Benedikt Weissbrich, Andrea Streng, Johannes G Liese BMC Research Notes 2012, 5:304 (18 June 2012)

Abstract | Full text | PDF | PubMed

66.

Research   Open Access

A multi-institution evaluation of deformable image registration algorithms for automatic organ delineation in adaptive head and neck radiotherapy

Nicholas Hardcastle, Wolfgang A Tomé, Donald M Cannon, Charlotte L Brouwer, Paul WH Wittendorp, Nesrin Dogan, Matthias Guckenberger, Stéphane Allaire, Yogish Mallya, Prashant Kumar, Markus Oechsner, Anne Richter, Shiyu Song, Michael Myers, Bülent Polat, Karl Bzdusek Radiation Oncology 2012, 7:90 (15 June 2012)

Abstract | Full text | PDF | PubMed

67.

Research   Open Access

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain

Bernhard T Baune, Carsten Konrad, Dominik Grotegerd, Thomas Suslow, Eva Birosova, Patricia Ohrmann, Jochen Bauer, Volker Arolt, Walter Heindel, Katharina Domschke, Sonja Schöning, Astrid V Rauch, Christina Uhlmann, Harald Kugel, Udo Dannlowski Journal of Neuroinflammation 2012, 9:125 (13 June 2012)

Abstract | Full text | PDF | PubMed

68.

Review   Open Access Highly Accessed

Accuracy and inter-observer variability of 3D versus 4D cone-beam CT based image-guidance in SBRT for lung tumors

Reinhart A Sweeney, Benedikt Seubert, Silke Stark, Vanessa Homann, Gerd Müller, Michael Flentje, Matthias Guckenberger Radiation Oncology 2012, 7:81 (8 June 2012)

Abstract | Full text | PDF | PubMed

69.

Research article   Open Access

Tumor thrombus of inferior vena cava in patients with renal cell carcinoma – clinical and oncological outcome of 50 patients after surgery

Daniel Vergho, Andreas Loeser, Arkadius Kocot, Martin Spahn, Hubertus Riedmiller BMC Research Notes 2012, 5:264 (1 June 2012)

Abstract | Full text | PDF | PubMed

70.

Research article   Open Access Highly Accessed

A molecular signature in blood identifies early Parkinson’s disease

Leonid Molochnikov, Jose M Rabey, Evgenya Dobronevsky, Ubaldo Bonuccelli, Roberto Ceravolo, Daniela Frosini, Edna Grünblatt, Peter Riederer, Christian Jacob, Judith Aharon-Peretz, Yulia Bashenko, Moussa BH Youdim, Silvia A Mandel Molecular Neurodegeneration 2012, 7:26 (31 May 2012)

Abstract | Full text | PDF | PubMed

71.

Research article   Open Access Highly Accessed

Tumour size measurement in a mouse model using high resolution MRI

Mikael Montelius, Maria Ljungberg, Michael Horn, Eva Forssell-Aronsson BMC Medical Imaging 2012, 12:12 (30 May 2012)

Abstract | Full text | PDF | PubMed

72.

Review   Open Access

The 1027th target candidate in stroke: Will NADPH oxidase hold up?

Kim A Radermacher, Kirstin Wingler, Pamela Kleikers, Sebastian Altenhöfer, Johannes JR Hermans, Christoph Kleinschnitz, Harald HHW Schmidt Experimental & Translational Stroke Medicine 2012, 4:11 (24 May 2012)

Abstract | Full text | PDF | PubMed

73.

Review   Open Access Highly Accessed

Minimizing Risk of Nephrogenic systemic fibrosis in Cardiovascular Magnetic Resonance

Theresa Reiter, Oliver Ritter, Martin R Prince, Peter Nordbeck, Christoph Wanner, Eike Nagel, Wolfgang Bauer Journal of Cardiovascular Magnetic Resonance 2012, 14:31 (20 May 2012)

Abstract | Full text | PDF | PubMed

74.

Research   Open Access

The prototype foamy virus protease is active independently of the integrase domain

Ralf Spannaus, Maximilian J Hartl, Birgitta M Wöhrl, Axel Rethwilm, Jochen Bodem Retrovirology 2012, 9:41 (10 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper shows that the FV integrase is required for Pol encapsidation and that the FV PR activity is integrase independent. The study shows that an active PR can be encapsidated in trans as a GagPR-RT fusion protein.

75.

Research article   Open Access

Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress

Christoph Klingelhoeffer, Ulrike Kämmerer, Monika Koospal, Bettina Mühling, Manuela Schneider, Michaela Kapp, Alexander Kübler, Christoph-Thomas Germer, Christoph Otto BMC Complementary and Alternative Medicine 2012, 12:61 (2 May 2012)

Abstract | Full text | PDF | PubMed

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