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Member - Leibniz Institute for Age Research - Fritz Lipmann Institute

The institutes mission is to understand the molecular mechanisms that underlie ageing and that lead to age-related diseases. This knowledge will contribute to sustained health in an ageing society.

http://www.fli-leibniz.de

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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Leibniz Institute for Age Research - Fritz Lipmann Institute

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	1.	Research article Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis Stefan Taudien, Gabor Gäbel, Oliver Kuss, Marco Groth, Robert Grützmann, Klaus Huse, Alexander Kluttig, Andreas Wolf, Michael Nothnagel, Philip Rosenstiel, Karin Halina Greiser, Karl Werdan, Michael Krawczak, Christian Pilarsky, Matthias Platzer BMC Research Notes 2012, 5:629 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
	2.	Research article *Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus* reveals novel insights into the genome and MpkA dependent gene expression** Sebastian Müller, Clara Baldin, Marco Groth, Reinhard Guthke, Olaf Kniemeyer, Axel A Brakhage, Vito Valiante BMC Genomics 2012, 13:519 (2 October 2012) Abstract \| Full text \| PDF \| PubMed
	3.	Research article Sequencing of BAC pools by different next generation sequencing platforms and strategies Stefan Taudien, Burkhard Steuernagel, Ruvini Ariyadasa, Daniela Schulte, Thomas Schmutzer, Marco Groth, Marius Felder, Andreas Petzold, Uwe Scholz, Klaus FX Mayer, Nils Stein, Matthias Platzer BMC Research Notes 2011, 4:411 (14 October 2011) Abstract \| Full text \| PDF \| PubMed
	4.	Research article *From RNA-seq to large-scale genotyping - genomics resources for rye (Secale cereale* L.)** Grit Haseneyer, Thomas Schmutzer, Michael Seidel, Ruonan Zhou, Martin Mascher, Chris-Carolin Schön, Stefan Taudien, Uwe Scholz, Nils Stein, Klaus FX Mayer, Eva Bauer BMC Plant Biology 2011, 11:131 (28 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5.	Research article Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing Stefan Taudien, Karol Szafranski, Marius Felder, Marco Groth, Klaus Huse, Francesca Raffaelli, Andreas Petzold, Xinmin Zhang, Philip Rosenstiel, Jochen Hampe, Stefan Schreiber, Matthias Platzer BMC Genomics 2011, 12:243 (18 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6.	Research article Origin of land plants: Do conjugating green algae hold the key? Sabina Wodniok, Henner Brinkmann, Gernot Glöckner, Andrew J Heidel, Hervé Philippe, Michael Melkonian, Burkhard Becker BMC Evolutionary Biology 2011, 11:104 (18 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The closest living algal relative of the land plants appears to be the conjugating green algae rather than the stonewort-like algae, as revealed by phylogenetic analysis of 129 nuclear genes across a broad range of land plants and algal groups.
	7.	Research article *To be or not to be the odd one out - Allele-specific transcription in pentaploid dogroses (Rosa* L. sect. Caninae (DC.) Ser)** Christiane M Ritz, Ines Köhnen, Marco Groth, Günter Theißen, Volker Wissemann BMC Plant Biology 2011, 11:37 (23 February 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Characterization of the Rosa canina pentaploid genome reveals at least four different alleles present for each locus investigated, locating to bivalent and univalent chromosomes; all alleles are expressed suggesting the absence of unidirectional silencing seen in other allopolyploid systems.
	8.	Research Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi Anke Burmester, Ekaterina Shelest, Gernot Glöckner, Christoph Heddergott, Susann Schindler, Peter Staib, Andrew Heidel, Marius Felder, Andreas Petzold, Karol Szafranski, Marc Feuermann, Ivo Pedruzzi, Steffen Priebe, Marco Groth, Robert Winkler, Wenjun Li, Olaf Kniemeyer, Volker Schroeckh, Christian Hertweck, Bernhard Hube, Theodore C White, Matthias Platzer, Reinhard Guthke, Joseph Heitman, Johannes Wöstemeyer, Peter F Zipfel, Michel Monod, Axel A Brakhage Genome Biology 2011, 12:R7 (19 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Genome sequences from two dermatophytic fungi shed light on the biology and pathogenesis of these skin disease-causing organisms
	9.	Research article DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation Theresa Gorsler, Ulrike Murzik, Tobias Ulbricht, Julia Hentschel, Peter Hemmerich, Christian Melle BMC Cell Biology 2010, 11:100 (17 December 2010) Abstract \| Full text \| PDF \| PubMed
	10.	Research article *Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients* Mariya Y Radeva, Franziska Jahns, Anne Wilhelm, Michael Glei, Utz Settmacher, Karl Greulich, Henning Mothes BMC Cancer 2010, 10:588 (27 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11.	Letter to the Editor Potential negative impacts and low effectiveness in the use of African annual killifish in the biocontrol of aquatic mosquito larvae in temporary water bodies Martin Reichard, Brian R Watters, Rudolf H Wildekamp, Rainer Sonnenberg, Béla Nagy, Matej Polačik, Stefano Valdesalici, Alessandro Cellerino, Barry J Cooper, Holger Hengstler, John Rosenstock, Ian Sainthouse Parasites & Vectors 2010, 3:89 (16 September 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Low effectiveness, ecological threats and ethical issues related to a recent suggestion to use an African annual fish as a tool to control mosquito larvae in temporary freshwater habitats are discussed. Image: Wild-caught male Nothobranchius guentheri from Zanzibar Island (courtesy Brian R Watters).
	12.	Short Report NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner Marcel Kramer, Janne Boeck, Daniela Reichenbach, Christoph Kaether, Stefan Schreiber, Matthias Platzer, Philip Rosenstiel, Klaus Huse BMC Research Notes 2010, 3:224 (10 August 2010) Abstract \| Full text \| PDF \| PubMed
	13.	Research article Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system Anna Ivanova, Jens Wuerfel, Juan Zhang, Olaf Hoffmann, Matthias Ballmaier, Christof Dame BMC Developmental Biology 2010, 10:77 (28 July 2010) Abstract \| Full text \| PDF \| PubMed
	14.	Research article *Characterisation of prostate cancer lesions in heterozygous Men1* mutant mice** Christelle Seigne, Sandra Fontanière, Christine Carreira, Jieli Lu, Wei-Ming Tong, Bernard Fontanière, Zhao-Qi Wang, Chang Zhang, Lucien Frappart BMC Cancer 2010, 10:395 (27 July 2010) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	15.	Research article Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor Raoul Frijters, Wilco Fleuren, Erik JM Toonen, Jan P Tuckermann, Holger M Reichardt, Hans van der Maaden, Andrea van Elsas, Marie-Jose van Lierop, Wim Dokter, Jacob de Vlieg, Wynand Alkema BMC Genomics 2010, 11:359 (5 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	16.	Database TassDB2 - A comprehensive database of subtle alternative splicing events Rileen Sinha, Thorsten Lenser, Niels Jahn, Ulrike Gausmann, Swetlana Friedel, Karol Szafranski, Klaus Huse, Philip Rosenstiel, Jochen Hampe, Stefan Schuster, Michael Hiller, Rolf Backofen, Matthias Platzer BMC Bioinformatics 2010, 11:216 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17.	Research article Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens Rileen Sinha, Andreas D Zimmer, Kathrin Bolte, Daniel Lang, Ralf Reski, Matthias Platzer, Stefan A Rensing, Rolf Backofen BMC Plant Biology 2010, 10:76 (28 April 2010) Abstract \| Full text \| PDF \| PubMed
	18.	Research article Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing Stefan Taudien, Marco Groth, Klaus Huse, Andreas Petzold, Karol Szafranski, Jochen Hampe, Philip Rosenstiel, Stefan Schreiber, Matthias Platzer BMC Genomics 2010, 11:252 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19.	Research article Comparative gene expression in toxic versus non-toxic strains of the marine dinoflagellate Alexandrium minutum Ines Yang, Uwe John, Sára Beszteri, Gernot Glöckner, Bernd Krock, Alexander Goesmann, Allan D Cembella BMC Genomics 2010, 11:248 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20.	Research A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization Sven Jarius, Klaus P Wandinger, Sigrun Horn, Heike Heuer, Brigitte Wildemann Journal of Neuroinflammation 2010, 7:21 (12 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	21.	Research article Assembly dynamics of PML nuclear bodies in living cells Peter Brand, Thorsten Lenser, Peter Hemmerich PMC Biophysics 2010, 3:3 (5 March 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Promyelocytic leukemia nuclear bodies (PML NBs) are involved in the regulation of apoptosis, antiviral responses, the DNA damage response and chromatin structure, but their precise biochemical function in these nuclear pathways is unknown. In this study we determined PML NB assembly dynamics by live cell imaging, combined with mathematical modeling.
	22.	Research article Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum Israel Barrantes, Gernot Glockner, Sonja Meyer, Wolfgang Marwan BMC Genomics 2010, 11:115 (17 February 2010) Abstract \| Full text \| PDF \| PubMed
	23.	Research article Transcriptome analysis of the sex pheromone gland of the noctuid moth Heliothis virescens Heiko Vogel, Andrew J Heidel, David G Heckel, Astrid T Groot BMC Genomics 2010, 11:29 (14 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24.	Methodology article De novo 454 sequencing of barcoded BAC pools for comprehensive gene survey and genome analysis in the complex genome of barley Burkhard Steuernagel, Stefan Taudien, Heidrun Gundlach, Michael Seidel, Ruvini Ariyadasa, Daniela Schulte, Andreas Petzold, Marius Felder, Andreas Graner, Uwe Scholz, Klaus FX Mayer, Matthias Platzer, Nils Stein BMC Genomics 2009, 10:547 (20 November 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25.	Research article Adapted Boolean network models for extracellular matrix formation Johannes Wollbold, René Huber, Dirk Pohlers, Dirk Koczan, Reinhard Guthke, Raimund W Kinne, Ulrike Gausmann BMC Systems Biology 2009, 3:77 (21 July 2009) Abstract \| Full text \| PDF \| PubMed