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51.

Research article   Open Access Highly Accessed

Effect of environmental stress factors on the uptake and survival of Campylobacter jejuni in Acanthamoeba castellanii

Xuan Bui, Klaus Qvortrup, Anders Wolff, Dang Bang, Carole Creuzenet BMC Microbiology 2012, 12:232 (11 October 2012)

Abstract | Full text | PDF | PubMed

52.

Research   Open Access

Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury

Sucheol Gil, Alex W Farnand, William A Altemeier, Sean E Gill, Anna Kurdowska, Agnieszka Krupa, Jon M Florence, Gustavo Matute-Bello Respiratory Research 2012, 13:91 (9 October 2012)

Abstract | Full text | PDF | PubMed

53.

Research article   Open Access

Cost-effectiveness of a 21-gene recurrence score assay versus Canadian clinical practice in women with early-stage estrogen- or progesterone-receptor-positive, axillary lymph-node negative breast cancer

Malek B Hannouf, Bin Xie, Muriel Brackstone, Gregory S Zaric BMC Cancer 2012, 12:447 (2 October 2012)

Abstract | Full text | PDF | PubMed

54.

Research   Open Access

Doxycycline impairs neutrophil migration to the airspaces of the lung in mice exposed to intratracheal lipopolysaccharide

Andres Moon, Sucheol Gil, Sean E Gill, Peter Chen, Gustavo Matute-Bello Journal of Inflammation 2012, 9:31 (3 September 2012)

Abstract | Full text | PDF | PubMed

55.

Research   Open Access

Direct path detection using multipath interference cancelation for communication-based positioning system

Jiaxin Yang, Xianbin Wang, Sung Park, Heung Kim EURASIP Journal on Advances in Signal Processing 2012, 2012:188 (30 August 2012)

Abstract | Full text | PDF

56.

Research article   Open Access

Priorities for research in child maltreatment, intimate partner violence and resilience to violence exposures: results of an international Delphi consensus development process

C Wathen, Jennifer CD MacGregor, Joanne Hammerton, Jeffrey H Coben, Helen Herrman, Donna E Stewart, Harriet L MacMillan, BMC Public Health 2012, 12:684 (21 August 2012)

Abstract | Full text | PDF | PubMed

57.

Research article   Open Access

Perceptions of cardiac rehabilitation patients, specialists and rehabilitation programs regarding cardiac rehabilitation wait times

Sherry L Grace, Yongyao Tan, Louise Marcus, William Dafoe, Chris Simpson, Neville Suskin, Caroline Chessex BMC Health Services Research 2012, 12:259 (16 August 2012)

Abstract | Full text | PDF | PubMed

58.

Research   Open Access Highly Accessed

Social determinants of health in Canada: Are healthy living initiatives there yet? A policy analysis

Dana Gore, Anita Kothari International Journal for Equity in Health 2012, 11:41 (14 August 2012)

Abstract | Full text | PDF | PubMed

59.

Research   Open Access

Factors affecting the value of environmental predictions to the energy sector

Matt Davison, Ozgur Gurtuna, Claude Masse, Brian Mills Environmental Systems Research 2012, 1:4 (14 August 2012)

Abstract | Full text | PDF

60.

Research   Open Access

What is the role and authority of gatekeepers in cluster randomized trials in health research?

Antonio Gallo, Charles Weijer, Angela White, Jeremy M Grimshaw, Robert Boruch, Jamie C Brehaut, Allan Donner, Martin P Eccles, Andrew D McRae, Raphael Saginur, Merrick Zwarenstein, Monica Taljaard Trials 2012, 13:116 (26 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

61.

Review   Open Access Highly Accessed

CSACI Position statement on the testing of food-specific IgG

Stuart Carr, Edmond Chan, Elana Lavine, William Moote Allergy, Asthma & Clinical Immunology 2012, 8:12 (26 July 2012)

Abstract | Full text | PDF | PubMed

62.

Primary research   Open Access

Reducing treatment delay for early intervention: evaluation of a community based crisis helpline

Amresh K Shrivastava, Megan E Johnston, Larry Stitt, Meghana Thakar, Gopa Sakel, Sunita Iyer, Nilesh Shah, Yves Bureau Annals of General Psychiatry 2012, 11:20 (24 July 2012)

Abstract | Full text | PDF | PubMed

63.

Study protocol   Open Access

Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): Study protocol for a randomized phase II trial

David A Palma, Cornelis J A Haasbeek, George B Rodrigues, Max Dahele, Michael Lock, Brian Yaremko, Robert Olson, Mitchell Liu, Jason Panarotto, GwendolynHMJ Griffioen, Stewart Gaede, Ben Slotman, Suresh Senan BMC Cancer 2012, 12:305 (23 July 2012)

Abstract | Full text | PDF | PubMed

64.

Research article   Open Access Highly Accessed

BRCA2 Variants and cardiovascular disease in a multi-ethnic study

Kevin Zbuk, Changchun Xie, Robin Young, Mahyar Heydarpour, Guillaume Pare, A Davis, Ruby Miller, Matthew B Lanktree, Danish Saleheen, John Danesh, Salim Yusuf, James C Engert, Robert A Hegele, Sonia S Anand BMC Medical Genetics 2012, 13:56 (18 July 2012)

Abstract | Full text | PDF | PubMed

65.

Research article   Open Access

Transposable elements in phytopathogenic Verticillium spp.: insights into genome evolution and inter- and intra-specific diversification

Stefan G Amyotte, Xiaoping Tan, Kayla Pennerman, Maria del Mar Jimenez-Gasco, Steven J Klosterman, Li-Jun Ma, Katherine F Dobinson, Paola Veronese BMC Genomics 2012, 13:314 (16 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

66.

Research article   Open Access

Cysteine peptidases and their inhibitors in Tetranychus urticae: a comparative genomic approach

María Santamaría, Pedro Hernández-Crespo, Félix Ortego, Vojislava Grbic, Miodrag Grbic, Isabel Diaz, Manuel Martinez BMC Genomics 2012, 13:307 (11 July 2012)

Abstract | Full text | PDF | PubMed

67.

Research article   Open Access Highly Accessed

Prevalence, determinants and co-morbidities of chronic kidney disease among First Nations adults with diabetes: results from the CIRCLE study

Roland F Dyck, Mariam Naqshbandi Hayward, Stewart B Harris, BMC Nephrology 2012, 13:57 (9 July 2012)

Abstract | Full text | PDF | PubMed

68.

Research article   Open Access Highly Accessed

Impact of a computerized system for evidence-based diabetes care on completeness of records: a before–after study

Pavel S Roshanov, Hertzel C Gerstein, Dereck L Hunt, Rolf J Sebaldt, R Haynes BMC Medical Informatics and Decision Making 2012, 12:63 (7 July 2012)

Abstract | Full text | PDF | PubMed

69.

Research article   Open Access Highly Accessed

The quality of reporting of RCTs used within a postoperative pain management meta-analysis, using the CONSORT statement

Victoria Borg Debono, Shiyuan Zhang, Chenglin Ye, James Paul, Aman Arya, Lindsay Hurlburt, Yamini Murthy, Lehana Thabane BMC Anesthesiology 2012, 12:13 (4 July 2012)

Abstract | Full text | PDF | PubMed

70.

Research   Open Access

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Raymond H Thomas, Melissa M Meeking, Jennifer R Mepham, Lisa Tichenoff, Fred Possmayer, Suya Liu, Derrick F MacFabe Journal of Neuroinflammation 2012, 9:153 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

71.

Research article   Open Access

A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations

Rohan D Gidvani, Peter Sudmant, Grace Li, Lance F DaSilva, Brendan J McConkey, Bernard P Duncker, Brian P Ingalls BMC Systems Biology 2012, 6:78 (27 June 2012)

Abstract | Full text | PDF | PubMed

72.

Research article   Open Access Highly Accessed

Why physicians and nurses ask (or don’t) about partner violence: a qualitative analysis

Charlene E Beynon, Iris A Gutmanis, Leslie M Tutty, C Wathen, Harriet L MacMillan BMC Public Health 2012, 12:473 (21 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

73.

Research article   Open Access

Glomerular disease search filters for Pubmed, Ovid Medline, and Embase: a development and validation study

Ainslie M Hildebrand, Arthur V Iansavichus, Christopher WC Lee, R Haynes, Nancy L Wilczynski, K McKibbon, Michelle A Hladunewich, William F Clark, Daniel C Cattran, Amit X Garg BMC Medical Informatics and Decision Making 2012, 12:49 (6 June 2012)

Abstract | Full text | PDF | PubMed

74.

Study protocol   Open Access

An interdisciplinary knowledge translation intervention in long-term care: Study protocol for the vitamin D and osteoporosis study (ViDOS) pilot cluster randomized controlled trial

Courtney C Kennedy, George Ioannidis, Lora M Giangregorio, Jonathan D Adachi, Lehana Thabane, Suzanne N Morin, Richard G Crilly, Sharon Marr, Robert G Josse, Lynne Lohfeld, Laura E Pickard, Susanne King, Mary-Lou van der Horst, Glenda Campbell, Jackie Stroud, Lisa Dolovich, Anna M Sawka, Ravi Jain, Lynn Nash, Alexandra Papaioannou Implementation Science 2012, 7:48 (24 May 2012)

Abstract | Full text | PDF | PubMed

75.

Hypothesis   Open Access

Decoding the informational properties of the RNA polymerase II Carboxy Terminal Domain

Jim Karagiannis BMC Research Notes 2012, 5:241 (16 May 2012)

Abstract | Full text | PDF | PubMed

76.

Research   Open Access Highly Accessed

Skin prick testing with extensively heated milk or egg products helps predict the outcome of an oral food challenge: a retrospective analysis

Zein Faraj, Harold L Kim Allergy, Asthma & Clinical Immunology 2012, 8:5 (16 May 2012)

Abstract | Full text | PDF | PubMed

77.

Research article   Open Access Highly Accessed

Mcm2 phosphorylation and the response to replicative stress

Brent E Stead, Christopher J Brandl, Matthew K Sandre, Megan J Davey BMC Genetics 2012, 13:36 (7 May 2012)

Abstract | Full text | PDF | PubMed

78.

Research article   Open Access

“Completely out-at-sea” with “two-gender medicine”: A qualitative analysis of physician-side barriers to providing healthcare for transgender patients

John W Snelgrove, Amanda M Jasudavisius, Bradley W Rowe, Evan M Head, Greta R Bauer BMC Health Services Research 2012, 12:110 (4 May 2012)

Abstract | Full text | PDF | PubMed

79.

Research article   Open Access

Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture

Latha Satish, William A LaFramboise, Sandra Johnson, Linda Vi, Anna Njarlangattil, Christina Raykha, John Michael Krill-Burger, Phillip H Gallo, David B O'Gorman, Bing Gan, Mark E Baratz, Garth D Ehrlich, Sandeep Kathju BMC Medical Genomics 2012, 5:15 (4 May 2012)

Abstract | Full text | PDF | PubMed

80.

Research   Open Access

A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe

Charnpal Grewal, Jack Hickmott, Stefan Rentas, Jim Karagiannis Cell Division 2012, 7:13 (4 May 2012)

Abstract | Full text | PDF | PubMed

81.

Short paper   Open Access Highly Accessed

Active video games: the mediating effect of aerobic fitness on body composition

Ralph Maddison, Cliona Mhurchu, Andrew Jull, Harry Prapavessis, Louise S Foley, Yannan Jiang International Journal of Behavioral Nutrition and Physical Activity 2012, 9:54 (3 May 2012)

Abstract | Full text | PDF | PubMed

82.

Review   Open Access Highly Accessed

Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise

Emily C Keats, Zia A Khan Cardiovascular Diabetology 2012, 11:37 (23 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

Research article   Open Access Highly Accessed

High heterogeneity of HIV-related sexual risk among transgender people in Ontario, Canada: a province-wide respondent-driven sampling survey

Greta R Bauer, Robb Travers, Kyle Scanlon, Todd A Coleman BMC Public Health 2012, 12:292 (20 April 2012)

Abstract | Full text | PDF | PubMed

84.

Original research   Open Access

Experimental and theoretical simulation of sublimating dusty water ice with implications for D/H ratios of water ice on Comets and Mars

John E Moores, Robert H Brown, Dante S Lauretta, Peter H Smith Planetary Science 2012, 1:2 (20 April 2012)

Abstract | Full text | PDF

85.

Research article   Open Access Highly Accessed

An optimal search filter for retrieving systematic reviews and meta-analyses

Edwin Lee, Maureen Dobbins, Kara DeCorby, Lyndsey McRae, Daiva Tirilis, Heather Husson BMC Medical Research Methodology 2012, 12:51 (18 April 2012)

Abstract | Full text | PDF | PubMed

86.

Short Report   Open Access Highly Accessed

Hemolytic anemia following intravenous immunoglobulin therapy in patients treated for Kawasaki disease: a report of 4 cases

Roberta Berard, Blair Whittemore, Rosie Scuccimarri Pediatric Rheumatology 2012, 10:10 (16 April 2012)

Abstract | Full text | PDF | PubMed

87.

Research   Open Access

Using learned under-sampling pattern for increasing speed of cardiac cine MRI based on compressive sensing principles

Pooria Zamani, Mohammad Kayvanrad, Hamid Soltanian-Zadeh EURASIP Journal on Advances in Signal Processing 2012, 2012:82 (13 April 2012)

Abstract | Full text | PDF

88.

Research   Open Access

Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition

Crystal R Whitfield, Brian H Shilton, David B Haniford Mobile DNA 2012, 3:7 (13 April 2012)

Abstract | Full text | PDF | PubMed

89.

Research   Open Access Highly Accessed

Loss of PPARγ expression by fibroblasts enhances dermal wound closure

Wei Sha, Katherine Thompson, Jennifer South, Murray Baron, Andrew Leask Fibrogenesis & Tissue Repair 2012, 5:5 (13 April 2012)

Abstract | Full text | PDF | PubMed

90.

Research article   Open Access

The publication of ethically uncertain research: attitudes and practices of journal editors

Carla Angelski, Conrad V Fernandez, Charles Weijer, Jun Gao BMC Medical Ethics 2012, 13:4 (11 April 2012)

Abstract | Full text | PDF | PubMed

91.

Research   Open Access

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

Jillian C Belrose, Yu-Feng Xie, Lynn J Gierszewski, John F MacDonald, Michael F Jackson Molecular Brain 2012, 5:11 (9 April 2012)

Abstract | Full text | PDF | PubMed

92.

Software   Open Access Highly Accessed

The Transcription Factor Encyclopedia

Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Warren A Cheung, Xiao Cindy Zhang, Christopher TD Dickman, Debra L Fulton, Jonathan S Lim, Jake M Schnabl, Oscar HP Ramos, Mireille Vasseur-Cognet, Charles N de Leeuw, Elizabeth M Simpson, Gerhart U Ryffel, Eric W-F Lam, Ralf Kist, Miranda SC Wilson, Raquel Marco-Ferreres, Jan J Brosens, Leonardo L Beccari, Paola Bovolenta, Bérénice A Benayoun, Lara J Monteiro, Helma DC Schwenen, Lars Grontved, Elizabeth Wederell, Susanne Mandrup, Reiner A Veitia et al. Genome Biology 2012, 13:R24 (29 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

A high quality compendium of transcription factor data that allows researchers to add new data via a peer-review system

93.

Original investigation   Open Access Highly Accessed

Cardiovascular disease risk profile and microvascular complications of diabetes: comparison of Indigenous cohorts with diabetes in Australia and Canada

Louise J Maple-Brown, Joan Cunningham, Bernard Zinman, Mary Mamakeesick, Stewart B Harris, Philip W Connelly, Jonathan Shaw, Kerin O'Dea, Anthony J Hanley Cardiovascular Diabetology 2012, 11:30 (28 March 2012)

Abstract | Full text | PDF | PubMed

94.

Research article   Open Access Highly Accessed

Effective lifestyle interventions to improve type II diabetes self-management for those with schizophrenia or schizoaffective disorder: a systematic review

Adriana Cimo, Erene Stergiopoulos, Chiachen Cheng, Sarah Bonato, Carolyn S Dewa BMC Psychiatry 2012, 12:24 (23 March 2012)

Abstract | Full text | PDF | PubMed

95.

Research article   Open Access

Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1

Stephanie Kvas, Gregory B Gloor, Christopher J Brandl BMC Genetics 2012, 13:19 (22 March 2012)

Abstract | Full text | PDF | PubMed

96.

Study protocol   Open Access

A phase II multi-institutional study assessing simultaneous in-field boost helical tomotherapy for 1-3 brain metastases

George Rodrigues, Slav Yartsev, Keng Tay, Gregory R Pond, Frank Lagerwaard, Glenn Bauman Radiation Oncology 2012, 7:42 (21 March 2012)

Abstract | Full text | PDF | PubMed

97.

Preliminary communication   Open Access

Filming a live cell by scanning electrochemical microscopy: label-free imaging of the dynamic morphology in real time

Michelle Zhang, Yi-Tao Long, Zhifeng Ding Chemistry Central Journal 2012, 6:20 (21 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A non-invasive, label-free and high resolution method has been developed to film live cells in real time using scanning electrochemical microscopy. The method was demonstrated by showing the dynamic morphology of a live human bladder cancer cell

98.

Poster presentation   Free

Liver transplantation in the critically ill: a Canadian collaboration

C Karvellas, T Lescot, H Vahidy, P Goldberg, P Chaudhury, P Metrakos, N Kneteman, G Meeberg, M Sharpe, J Ronco, E Renner, E Cook, S Bagshaw Critical Care 2012, 16(Suppl 1):P395 (20 March 2012)

Full text | PDF

99.

Poster presentation   Free

Effect of critical illness on the pharmacokinetics and dose-response relationship of midazolam

D Ovakim, KJ Bosma, GB Young, M Sen, LE Norton, F Priestap, RG Tirona, R Kim, GK Dresser Critical Care 2012, 16(Suppl 1):P330 (20 March 2012)

Full text | PDF

100.

Poster presentation   Free

Corticosteroids for critically ill patients: an international survey of intensivists

F Lamontagne, N Adhikari, D Cook, KK Koo, F Lauzier, KE Burns, I Douglas, AF Turgeon, H Quiroz, Y Poulin, K Choong, N Ferguson, ME Kho, M Duffett, C Chant, O Lesur, MO Meade Critical Care 2012, 16(Suppl 1):P101 (20 March 2012)

Full text | PDF

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