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1.

Research   Open Access

Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder

Tewarit Sarachana, Valerie W Hu Molecular Autism 2013, 4:14 (22 May 2013)

Abstract | Provisional PDF

2.

Perspective   Open Access Highly Accessed

Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise

William T Riley, Russell E Glasgow, Lynn Etheredge, Amy P Abernethy Clinical and Translational Medicine 2013, 2:10 (10 May 2013)

Abstract | Full text | PDF | PubMed

3.

Research   Open Access

Characteristics of children with the best and poorest first- and second-year growth during rhGH therapy: data from 25 years of the Genentech national cooperative growth study (NCGS)

Paul B Kaplowitz, Dorothy I Shulman, James W Frane, Joan Jacobs, Barbara Lippe International Journal of Pediatric Endocrinology 2013, 2013:9 (1 May 2013)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access Highly Accessed

A phylogeny and revised classification of Squamata, including 4161 species of lizards and snakes

Robert Alexander Pyron, Frank T Burbrink, John J Wiens BMC Evolutionary Biology 2013, 13:93 (29 April 2013)

Abstract | Provisional PDF | PubMed

5.

Research   Open Access

Obsessed maniacs and clairvoyant oracles: empirically validated patterns of entrepreneurial behavior

Elias G Carayannis, McDonald R Stewart Journal of Innovation and Entrepreneurship 2013, 2:2 (9 April 2013)

Abstract | Full text | PDF

6.

Research   Open Access

miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors

Naoe Harafuji, Peter Schneiderat, Maggie C Walter, Yi-Wen Chen Orphanet Journal of Rare Diseases 2013, 8:55 (5 April 2013)

Abstract | Full text | PDF | PubMed

7.

Methodology article   Open Access Highly Accessed

Differential expression analysis for paired RNA-seq data

Lisa M Chung, John P Ferguson, Wei Zheng, Feng Qian, Vincent Bruno, Ruth R Montgomery, Hongyu Zhao BMC Bioinformatics 2013, 14:110 (27 March 2013)

Abstract | Full text | PDF | PubMed

8.

Poster presentation   Free

Strong ion gap can be accurately estimated with a simple bedside equation

L Busse, L Chawla, R Panchamia, D Choi, E Nobakht, E Brasha-Mitchell, M Seneff Critical Care 2013, 17(Suppl 2):P444 (19 March 2013)

Full text | PDF

9.

Research   Open Access

Stereotactic radiosurgery for single brain metastases from non-small cell lung cancer: progression of extracranial disease correlates with distant intracranial failure

Marie-Adele S Kress, Eric Oermann, Matthew G Ewend, Riane B Hoffman, Huma Chaudhry, Brian Collins Radiation Oncology 2013, 8:64 (19 March 2013)

Abstract | Full text | PDF | PubMed

10.

Poster presentation   Open Access

Nuclear envelope laminopathies: evidence for developmentally inappropriate chromatin-nuclear envelope interactions

Jelena Perovanovic, Jyoti Jaiswal, Nikola Markovic, Eric Hoffman Epigenetics & Chromatin 2013, 6(Suppl 1):P65 (18 March 2013)

Full text | PDF

11.

Research   Open Access

Dystechnia: a model of technology deficiency and implications for entrepreneurial opportunity

McDonald R Stewart, Elias G Carayannis Journal of Innovation and Entrepreneurship 2013, 2:1 (18 March 2013)

Abstract | Full text | PDF

12.

Research article   Open Access

Pathogen-specific risk of chronic gastrointestinal disorders following bacterial causes of foodborne illness

Chad K Porter, Daniel Choi, Brooks Cash, Mark Pimentel, Joseph Murray, Larissa May, Mark S Riddle BMC Gastroenterology 2013, 13:46 (8 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

Methodology   Open Access

The work environment disability-adjusted life year for use with life cycle assessment: a methodological approach

Kelly A Scanlon, George M Gray, Royce A Francis, Shannon M Lloyd, Peter LaPuma Environmental Health 2013, 12:21 (6 March 2013)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access

Compressive sensing in distributed radar sensor networks using pulse compression waveforms

Lei Xu, Qilian Liang, Xiuzhen Cheng, Dechang Chen EURASIP Journal on Wireless Communications and Networking 2013, 2013:36 (19 February 2013)

Abstract | Full text | PDF

15.

Research   Open Access Highly Accessed

Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

Kianoush Kashani, Ali Al-Khafaji, Thomas Ardiles, Antonio Artigas, Sean M Bagshaw, Max Bell, Azra Bihorac, Robert Birkhahn, Cynthia M Cely, Lakhmir S Chawla, Danielle L Davison, Thorsten Feldkamp, Lui G Forni, Michelle Gong, Kyle J Gunnerson, Michael Haase, James Hackett, Patrick M Honore, Eric AJ Hoste, Olivier Joannes-Boyau, Michael Joannidis, Patrick Kim, Jay L Koyner, Daniel T Laskowitz, Matthew E Lissauer, Gernot Marx, Peter A McCullough, Scott Mullaney, Marlies Ostermann, Thomas Rimmelé et al. Critical Care 2013, 17:R25 (6 February 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Urine TIMP-2, and IGFBP7, two novel biomarkers for risk stratification of acute kidney injury, have been discovered and validated in more than 1000 critically ill patients. 

16.

Review   Open Access Highly Accessed

E-learning in medical education in resource constrained low- and middle-income countries

Seble Frehywot, Yianna Vovides, Zohray Talib, Nadia Mikhail, Heather Ross, Hannah Wohltjen, Selam Bedada, Kristine Korhumel, Abdel Karim Koumare, James Scott Human Resources for Health 2013, 11:4 (4 February 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Review   Open Access

Mechanical contributors to sex differences in idiopathic knee osteoarthritis

Daniel P Nicolella, Mary I O’Connor, Roger M Enoka, Barbara D Boyan, David A Hart, Eileen Resnick, Karen J Berkley, Kathleen A Sluka, C Kent Kwoh, Laura L Tosi, Richard D Coutts, Lorena M Havill, Wendy M Kohrt Biology of Sex Differences 2012, 3:28 (23 December 2012)

Abstract | Full text | PDF | PubMed

18.

Editorial   Open Access

Current Opinion on Nanotoxicology

Ali Pourmand, Mohammad Abdollahi DARU Journal of Pharmaceutical Sciences 2012, 20:95 (15 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

There are challenges on nanotoxicology that need to be taken care of properly. Materials that might prove to be significantly toxic must be identified. A system for the categorization of nanomaterials must be codified and made available to toxicologists. Also better understanding of nanomaterials biological interactions must be obtained. As requiring toxicologists to become nanotechnology experts would not be feasible, to properly incorporate the care of nanotoxicity into the existing medical framework, a range of experts across multiple fields of study must work in close synchronization. The focus needs to be on mechanism-driven research to ensure a solid scientific foundation for the assessment of nanomaterials and their role in healthcare.

19.

Research article   Open Access Highly Accessed

Pilot evaluation of the text4baby mobile health program

William Douglas Evans, Jasmine L Wallace, Jeremy Snider BMC Public Health 2012, 12:1031 (26 November 2012)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

Immune correlates of aging in outdoor-housed captive rhesus macaques (Macaca mulatta)

Elizabeth S Didier, Chie Sugimoto, Lisa C Bowers, Imtiaz A Khan, Marcelo J Kuroda Immunity & Ageing 2012, 9:25 (14 November 2012)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access

The influence of climatic conditions on the transmission dynamics of the 2009 A/H1N1 influenza pandemic in Chile

Gerardo Chowell, Sherry Towers, Cécile Viboud, Rodrigo Fuentes, Viviana Sotomayor, Lone Simonsen, Mark A Miller, Mauricio Lima, Claudia Villarroel, Monica Chiu, Jose E Villarroel, Andrea Olea BMC Infectious Diseases 2012, 12:298 (13 November 2012)

Abstract | Full text | PDF | PubMed

22.

Research article   Open Access

Duration of patients’ visits to the hospital emergency department

Zeynal Karaca, Herbert S Wong, Ryan L Mutter BMC Emergency Medicine 2012, 12:15 (6 November 2012)

Abstract | Full text | PDF | PubMed

23.

Review article   Open Access

Perspective on lead toxicity, a comparison between the United States and Iran

Ali Pourmand, Tareq Khedir Al-tiae, Maryann Mazer-Amirshahi DARU Journal of Pharmaceutical Sciences 2012, 20:70 (30 October 2012)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

Reintegration of child soldiers in Burundi: a tracer study

Mark JD Jordans, Ivan H Komproe, Wietse A Tol, Aline Ndayisaba, Theodora Nisabwe, Brandon A Kohrt BMC Public Health 2012, 12:905 (25 October 2012)

Abstract | Full text | PDF | PubMed

25.

Original article   Open Access

Ethnic persistence, assimilation and risk proclivity

Holger Bonin, Amelie Constant, Konstantinos Tatsiramos, Klaus F Zimmermann IZA Journal of Migration 2012, 1:5 (18 October 2012)

Abstract | Full text | PDF

26.

Research article   Open Access Highly Accessed

Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells

Georges St Laurent, Dmitry Shtokalo, Michael R Tackett, Zhaoqing Yang, Tatyana Eremina, Claes Wahlestedt, Silvio Urcuqui-Inchima, Bernd Seilheimer, Timothy A McCaffrey, Philipp Kapranov BMC Genomics 2012, 13:504 (24 September 2012)

Abstract | Full text | PDF | PubMed

27.

Research   Open Access

Eps homology domain endosomal transport proteins differentially localize to the neuromuscular junction

Suzanne E Mate, Jack H Van Der Meulen, Priyanka Arya, Sohinee Bhattacharyya, Hamid Band, Eric P Hoffman Skeletal Muscle 2012, 2:19 (13 September 2012)

Abstract | Full text | PDF | PubMed

28.

Editorial   Open Access

Application of nanomedicine in emergency medicine; Point-of-care testing and drug delivery in twenty - first century

Ali Pourmand, Mohammad Pourmand, Justin Wang, Robert Shesser DARU Journal of Pharmaceutical Sciences 2012, 20:26 (10 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

Research   Open Access

Are Dutch patients willing to be seen by a physician assistant instead of a medical doctor?

Luppo Kuilman, Roos MB Nieweg, Cees P van der Schans, Jaap H Strijbos, Roderick S Hooker Human Resources for Health 2012, 10:28 (4 September 2012)

Abstract | Full text | PDF | PubMed

30.

Editorial   Open Access

A survey of poison control centers worldwide

Ali Pourmand, Justin Wang, Maryann Mazer DARU Journal of Pharmaceutical Sciences 2012, 20:13 (28 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

There are some differences in number and activities of poison control centers (PIC) worldwide. In this paper, some PICs from some countries have been studied and compared. The comparison comes up with interesting data. I encourage readers to study this good article.

31.

Research   Open Access Highly Accessed

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model

Vanessa E Jahnke, Jack H Van Der Meulen, Helen K Johnston, Svetlana Ghimbovschi, Terrence Partridge, Eric P Hoffman, Kanneboyina Nagaraju Skeletal Muscle 2012, 2:16 (21 August 2012)

Abstract | Full text | PDF | PubMed

32.

Research   Open Access Highly Accessed

Virus-producing cells determine the host protein profiles of HIV-1 virion cores

Steven Santos, Yuri Obukhov, Sergei Nekhai, Michael Bukrinsky, Sergey Iordanskiy Retrovirology 2012, 9:65 (13 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Profiles of host proteins packaged in the cores of HIV-1 virions depend on the type of virus producing cell. The pool of proteins present in the cores of all virions is likely to contain factors important for viral functions.

33.

Research   Open Access

The Quintuple Helix innovation model: global warming as a challenge and driver for innovation

Elias G Carayannis, Thorsten D Barth, David FJ Campbell Journal of Innovation and Entrepreneurship 2012, 1:2 (8 August 2012)

Abstract | Full text | PDF

34.

Editorial   Open Access

Editorial preface to the first volume of Journal of Innovation and Entrepreneurship

Elias G Carayannis, David FJ Campbell Journal of Innovation and Entrepreneurship 2012, 1:1 (8 August 2012)

Abstract | Full text | PDF

35.

Viewpoint   Subscription Highly Accessed

Permissive hypofiltration

Lakhmir S Chawla, John A Kellum, Claudio Ronco Critical Care 2012, 16:317 (26 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

36.

Research   Open Access Highly Accessed

Effects of ultrasound and ultrasound contrast agent on vascular tissue

Steven C Wood, Sible Antony, Ronald P Brown, Jin Chen, Edward A Gordon, Victoria M Hitchins, Qin Zhang, Yunbo Liu, Subha Maruvada, Gerald R Harris Cardiovascular Ultrasound 2012, 10:29 (17 July 2012)

Abstract | Full text | PDF | PubMed

37.

Research   Open Access

Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

Junfang Wu, Ahdeah Pajoohesh-Ganji, Bogdan A Stoica, Michael Dinizo, Kelsey Guanciale, Alan I Faden Journal of Neuroinflammation 2012, 9:169 (11 July 2012)

Abstract | Full text | PDF | PubMed

38.

Research article   Open Access

Simultaneous delimitation of species and quantification of interspecific hybridization in Amazonian peacock cichlids (genus cichla) using multi-locus data

Stuart C Willis, Jason Macrander, Izeni P Farias, Guillermo Ortí BMC Evolutionary Biology 2012, 12:96 (22 June 2012)

Abstract | Full text | PDF | PubMed

39.

Research article   Open Access

Self-reported evaluation of competencies and attitudes by physicians-in-training before and after a single day legislative advocacy experience

Kristin M Huntoon, Colin J McCluney, Elizabeth A Wiley, Christopher A Scannell, Richard Bruno, Matthew J Stull BMC Medical Education 2012, 12:47 (22 June 2012)

Abstract | Full text | PDF | PubMed

40.

Research article   Open Access

IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse

Matthew C Kostek, Kanneboyina Nagaraju, Emidio Pistilli, Arpana Sali, San-Huei Lai, Brad Gordon, Yi-Wen Chen BMC Musculoskeletal Disorders 2012, 13:106 (20 June 2012)

Abstract | Full text | PDF | PubMed

41.

Poster presentation   Open Access

P02.112. Mind-body medicine therapies for the depression spectrum: a systematic review

S D'Silva, C Poscablo, R Habousha, B Kligler BMC Complementary and Alternative Medicine 2012, 12(Suppl 1):P168 (12 June 2012)

Full text | PDF

42.

Oral presentation   Open Access

Reconsidering the policy options to combat obesity

Christine Ferguson BMC Proceedings 2012, 6(Suppl 3):O5 (1 June 2012)

Full text | PDF

43.

Research article   Open Access

Risk of inflammatory bowel disease following a diagnosis of irritable bowel syndrome

Chad K Porter, Brooks D Cash, Mark Pimentel, Akintunde Akinseye, Mark S Riddle BMC Gastroenterology 2012, 12:55 (28 May 2012)

Abstract | Full text | PDF | PubMed

44.

Case report   Open Access

Case report: rapid spontaneous recovery from severe hypothyroidism in 2 teenage girls

Paul B Kaplowitz International Journal of Pediatric Endocrinology 2012, 2012:9 (2 May 2012)

Abstract | Full text | PDF | PubMed

45.

Review   Free

Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies

William Coley, Sree Rayavarapu, Kanneboyina Nagaraju Arthritis Research & Therapy 2012, 14:209 (27 April 2012)

Abstract | Full text | PDF | PubMed

46.

Research article   Open Access Highly Accessed

Impact of antiviral treatment and hospital admission delay on risk of death associated with 2009 A/H1N1 pandemic influenza in Mexico

Gerardo Chowell, Cécile Viboud, Lone Simonsen, Mark A Miller, Santiago Echevarría-Zuno, Margot González-León, Víctor H Borja Aburto BMC Infectious Diseases 2012, 12:97 (20 April 2012)

Abstract | Full text | PDF | PubMed

47.

Poster presentation   Open Access

Demographics and survival of AIDS cases with cancer, Washington, DC, 1996-2006

Heather A Young, Eric Engels, Ann-Marie Sufian-Kargbo, Alicia Vargas, Kathleen Rogers, Tiffany West, Amanda Castel Infectious Agents and Cancer 2012, 7(Suppl 1):P5 (19 April 2012)

Full text | PDF

48.

Review   Free Highly Accessed

Neurogenic pulmonary edema

Danielle L Davison, Megan Terek, Lakhmir S Chawla Critical Care 2012, 16:212 (20 March 2012)

Abstract | Full text | PDF | PubMed

49.

Poster presentation   Free

Effect of off-pump versus on-pump coronary artery bypass grafting in patients with chronic kidney disease

ME Schroeder, L Chawla, Y Zhao, F Lough, F Najam, M Seneff, JM Brennan Critical Care 2012, 16(Suppl 1):P347 (20 March 2012)

Full text | PDF

50.

Study protocol   Open Access

Progestogens to prevent preterm birth in twin pregnancies: an individual participant data meta-analysis of randomized trials

Ewoud Schuit, Sarah Stock, Rolf HH Groenwold, Kimberly Maurel, C Andrew Combs, Thomas Garite, Cathy Y Spong, Elizabeth A Thom, Dwight J Rouse, Steve N Caritis, George R Saade, Julia M Zachary, Jane E Norman, Line Rode, Katharina Klein, Ann Tabor, Elçin Çetingöz, John C Morrison, Everett F Magann, Christian M Briery, Vicente Serra, Alfredo Perales, Juan Meseguer, Anwar H Nassar, Arianne C Lim, Karel GM Moons, Anneke Kwee, Ben Willem J Mol BMC Pregnancy and Childbirth 2012, 12:13 (15 March 2012)

Abstract | Full text | PDF | PubMed

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