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1.

Methodology   Open Access

Principled missing data methods for researchers

Yiran Dong, Chao-Ying Joanne Peng SpringerPlus 2013, 2:222 (14 May 2013)

Abstract | Provisional PDF

2.

Research   Open Access

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy

Aylin Yilmaz, Constantin T Yiannoutsos, Dietmar Fuchs, Richard W Price, Kathryn Crozier, Lars Hagberg, Serena Spudich, Magnus Gisslén Journal of Neuroinflammation 2013, 10:62 (10 May 2013)

Abstract | Full text | PDF | PubMed

3.

Study protocol   Open Access

Medication adherence and tolerability of Alzheimer’s disease medications: study protocol for a randomized controlled trial

Noll L Campbell, Paul Dexter, Anthony J Perkins, Sujuan Gao, Lang Li, Todd C Skaar, Amie Frame, Hugh C Hendrie, Chris M Callahan, Malaz A Boustani Trials 2013, 14:125 (4 May 2013)

Abstract | Full text | PDF

4.

Research   Open Access

The housing first model (HFM) fidelity index: designing and testing a tool for measuring integrity of housing programs that serve active substance users

Dennis P Watson, John Orwat, Dana E Wagner, Valery Shuman, Randi Tolliver Substance Abuse Treatment, Prevention, and Policy 2013, 8:16 (3 May 2013)

Abstract | Full text | PDF | PubMed

5.

Research   Open Access Highly Accessed

CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

Quan Zhang, Mina Rho, Haixu Tang, Thomas G. Doak, Yuzhen Ye Genome Biology 2013, 14:R40 (29 April 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements

6.

Research article   Open Access

Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity

Sara Martinez-Pasamar, Elena Abad, Beatriz Moreno, Nieves Velez de Mendizabal, Ivan Martinez-Forero, Jordi Garcia-Ojalvo, Pablo Villoslada BMC Systems Biology 2013, 7:34 (26 April 2013)

Abstract | Full text | PDF | PubMed

7.

Research   Open Access

Ammonia-oxidizing archaea and bacteria are structured by geography in biological soil crusts across North American arid lands

Yevgeniy Marusenko, Scott T Bates, Ian Anderson, Shannon L Johnson, Tanya Soule, Ferran Garcia-Pichel Ecological Processes 2013, 2:9 (26 April 2013)

Abstract | Full text | PDF

8.

Research   Open Access

The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells

Hui Cai, Yan Xu Cell Communication and Signaling 2013, 11:31 (24 April 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

The “fossilized” mitochondrial genome of Liriodendron tulipifera: ancestral gene content and order, ancestral editing sites, and extraordinarily low mutation rate

Aaron O Richardson, Danny W Rice, Gregory J Young, Andrew J Alverson, Jeffrey D Palmer BMC Biology 2013, 11:29 (15 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The mitochondrial genome of the tulip tree has a remarkably slow rate of nucleotide substitution, and could offer insight into the content and organisation of this genome in the ancestral flowering plant.

10.

Case report   Open Access

Refractory bleeding from a chest wall sarcoma: a rare indication for palliative resection

Daniel J Weber, John J Coleman, Kenneth A Kesler Journal of Cardiothoracic Surgery 2013, 8:82 (12 April 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

Molecular cloning of doublesex genes of four cladocera (water flea) species

Kenji Toyota, Yasuhiko Kato, Masaru Sato, Naomi Sugiura, Shinichi Miyagawa, Hitoshi Miyakawa, Hajime Watanabe, Shigeto Oda, Yukiko Ogino, Chizue Hiruta, Takeshi Mizutani, Norihisa Tatarazako, Susanne Paland, Craig Jackson, John K Colbourne, Taisen Iguchi BMC Genomics 2013, 14:239 (10 April 2013)

Abstract | Full text | PDF | PubMed

12.

Research article   Open Access

An efficient post-hoc integration method improving peak alignment of metabolomics data from GCxGC/TOF-MS

Jaesik Jeong, Xiang Zhang, Xue Shi, Seongho Kim, Changyu Shen BMC Bioinformatics 2013, 14:123 (10 April 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Data dependence results of new multi-step and S-iterative schemes for contractive-like operators

Faik Gürsoy, Vatan Karakaya, Billy E Rhoades Fixed Point Theory and Applications 2013, 2013:76 (28 March 2013)

Abstract | Full text | PDF

14.

Review   Open Access

Drug-induced uveitis

Nikolas JS London, Sunir J Garg, Ramana S Moorthy, Emmett T Cunningham Journal of Ophthalmic Inflammation and Infection 2013, 3:43 (25 March 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access Highly Accessed

5'-Serial Analysis of Gene Expression studies reveal a transcriptomic switch during fruiting body development in Coprinopsis cinerea

Chi Keung Cheng, Chun Hang Au, Sarah K Wilke, Jason E Stajich, Miriam E Zolan, Patricia J Pukkila, Hoi Shan Kwan BMC Genomics 2013, 14:195 (20 March 2013)

Abstract | Full text | PDF | PubMed

16.

Research article   Open Access

Inducing extra copies of the Hsp70 gene in Drosophila melanogaster increases energetic demand

Luke A Hoekstra, Kristi L Montooth BMC Evolutionary Biology 2013, 13:68 (19 March 2013)

Abstract | Full text | PDF | PubMed

17.

Research article   Open Access

Uphill treadmill running does not induce histopathological changes in the rat Achilles tendon

Rachel C Dirks, Jeffrey S Richard, Angela M Fearon, Alexander Scott, Lauren G Koch, Steven L Britton, Stuart J Warden BMC Musculoskeletal Disorders 2013, 14:90 (11 March 2013)

Abstract | Full text | PDF | PubMed

18.

Research article   Open Access

Towards defining the chloroviruses: a genomic journey through a genus of large DNA viruses

Adrien Jeanniard, David D Dunigan, James R Gurnon, Irina V Agarkova, Ming Kang, Jason Vitek, Garry Duncan, O McClung, Megan Larsen, Jean-Michel Claverie, James L Van Etten, Guillaume Blanc BMC Genomics 2013, 14:158 (8 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment

19.

Methodology article   Open Access

Age-adjusted nonparametric detection of differential DNA methylation with case–control designs

Hanwen Huang, Zhongxue Chen, Xudong Huang BMC Bioinformatics 2013, 14:86 (6 March 2013)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

Enhancing sorafenib-mediated sensitization to gemcitabine in experimental pancreatic cancer through EMAP II

Niranjan Awasthi, Changhua Zhang, Stefan Hinz, Margaret A Schwarz, Roderich E Schwarz Journal of Experimental & Clinical Cancer Research 2013, 32:12 (6 March 2013)

Abstract | Full text | PDF | PubMed

21.

Research   Open Access

Functional genetic characterization of salivary gland development in Aedes aegypti

Chilinh Nguyen, Emily Andrews, Christy Le, Longhua Sun, Zeinab Annan, Anthony Clemons, David W Severson, Molly Duman-Scheel EvoDevo 2013, 4:9 (6 March 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Gaining the PROMIS perspective from children with nephrotic syndrome: a Midwest pediatric nephrology consortium study

Debbie S Gipson, David T Selewski, Susan F Massengill, Larysa Wickman, Kassandra L Messer, Emily Herreshoff, Corinna Bowers, Maria E Ferris, John D Mahan, Larry A Greenbaum, Jackie MacHardy, Gaurav Kapur, Deepa H Chand, Jens Goebel, Gina Barletta, Denis Geary, David B Kershaw, Cynthia G Pan, Rasheed Gbadegesin, Guillermo Hidalgo, Jerome C Lane, Jeffrey D Leiser, Brett W Plattner, Peter X Song, David Thissen, Yang Liu, Heather E Gross, Darren A DeWalt Health and Quality of Life Outcomes 2013, 11:30 (4 March 2013)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Why so many unknown genes? Partitioning orphans from a representative transcriptome of the lone star tick Amblyomma americanum

Amanda K Gibson, Zach Smith, Clay Fuqua, Keith Clay, John K Colbourne BMC Genomics 2013, 14:135 (27 February 2013)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access

Development of the Adult PedsQL™ Neurofibromatosis Type 1 Module: Initial Feasibility, Reliability and Validity

Kavitha Nutakki, Cynthia M Hingtgen, Patrick Monahan, James W Varni, Nancy L Swigonski Health and Quality of Life Outcomes 2013, 11:21 (21 February 2013)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access

Effects of donepezil 23 mg on Severe Impairment Battery domains in patients with moderate to severe Alzheimer's disease: evaluating the impact of baseline severity

Steven Ferris, Jeffrey Cummings, Daniel Christensen, Rachelle Doody, Martin Farlow, Marwan Sabbagh, Liang Liu, Joan Mackell, Randi Fain Alzheimer's Research & Therapy 2013, 5:12 (21 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Donepezil 23 mg/day provides significant benefits over 10 mg/day across a range of cognitive domains in patients with moderate to severe Alzheimer's disease, especially in the language domain.

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