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1.

Research   Open Access

Substantial increase in the frequency of circulating CD4+NKG2D+ T cells in patients with cervical intraepithelial neoplasia grade 1

Mariel Garcia-Chagollan, Luis F Jave-Suarez, Jesse Haramati, Pedro E Sanchez-Hernandez, Adriana Aguilar-Lemarroy, Miriam R Bueno-Topete, Ana L Pereira-Suarez, Mary Fafutis-Morris, Angel Cid-Arregui, Susana del Toro-Arreola Journal of Biomedical Science 2013, 20:60 (16 August 2013)

Abstract | Full text | PDF | PubMed

2.

Research   Open Access Highly Accessed

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

Keith R Bradnam, Joseph N Fass, Anton Alexandrov, Paul Baranay, Michael Bechner, Inanç Birol, Sébastien Boisvert, Jarrod A Chapman, Guillaume Chapuis, Rayan Chikhi, Hamidreza Chitsaz, Wen-Chi Chou, Jacques Corbeil, Cristian Del Fabbro, T Docking, Richard Durbin, Dent Earl, Scott Emrich, Pavel Fedotov, Nuno A Fonseca, Ganeshkumar Ganapathy, Richard A Gibbs, Sante Gnerre, Élénie Godzaridis, Steve Goldstein, Matthias Haimel, Giles Hall, David Haussler, Joseph B Hiatt, Isaac Y Ho et al. GigaScience 2013, 2:10 (22 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Assemblathon 2 is the largest systematic assessment of how the process of genome assembly is carried out, with 21 participating teams submitting 43 entries based on data from 3 different genomes

3.

Research article   Open Access Highly Accessed

Phylogenomics of strongylocentrotid sea urchins

Kord M Kober, Giacomo Bernardi BMC Evolutionary Biology 2013, 13:88 (23 April 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access Highly Accessed

The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage

H Bradley Shaffer, Patrick Minx, Daniel E Warren, Andrew M Shedlock, Robert C Thomson, Nicole Valenzuela, John Abramyan, Chris T Amemiya, Daleen Badenhorst, Kyle K Biggar, Glen M Borchert, Christopher W Botka, Rachel M Bowden, Edward L Braun, Anne M Bronikowski, Benoit G Bruneau, Leslie T Buck, Blanche Capel, Todd A Castoe, Mike Czerwinski, Kim D Delehaunty, Scott V Edwards, Catrina C Fronick, Matthew K Fujita, Lucinda Fulton, Tina A Graves, Richard E Green, Wilfried Haerty, Ramkumar Hariharan, Omar Hernandez et al. Genome Biology 2013, 14:R28 (28 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The genome of the western painted turtle, Chrysemys picta bellii, reveals insights into its extreme tolerance to anoxia and freezing

5.

Book review   Open Access Highly Accessed

Review of “Introduction to BioMEMS” by Albert Folch

Joel A Kubby BioMedical Engineering OnLine 2013, 12:25 (25 March 2013)

Abstract | Full text | PDF

6.

Research   Open Access Highly Accessed

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes

Adam D Ewing, Tracy J Ballinger, Dent Earl, Christopher C Harris, Li Ding, Richard K Wilson, David Haussler Genome Biology 2013, 14:R22 (13 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An analysis of gene retrocopy insertion polymorphisms in the germlines of individual humans, chimpanzees and mice, and in cancerous somatic tissues

7.

Proceedings   Open Access

Combining heterogeneous data sources for accurate functional annotation of proteins

Artem Sokolov, Christopher Funk, Kiley Graim, Karin Verspoor, Asa Ben-Hur BMC Bioinformatics 2013, 14(Suppl 3):S10 (28 February 2013)

Abstract | Full text | PDF | PubMed

8.

Research   Open Access

Stem cell biology is population biology: differentiation of hematopoietic multipotent progenitors to common lymphoid and myeloid progenitors

Marc Mangel, Michael B Bonsall Theoretical Biology and Medical Modelling 2013, 10:5 (17 January 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access

Bayesian semiparametric regression models to characterize molecular evolution

Saheli Datta, Abel Rodriguez, Raquel Prado BMC Bioinformatics 2012, 13:278 (30 October 2012)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access Highly Accessed

G-NEST: a gene neighborhood scoring tool to identify co-conserved, co-expressed genes

Danielle G Lemay, William F Martin, Angie S Hinrichs, Monique Rijnkels, J Bruce German, Ian Korf, Katherine S Pollard BMC Bioinformatics 2012, 13:253 (28 September 2012)

Abstract | Full text | PDF | PubMed

11.

Open letter   Free Highly Accessed

An encyclopedia of mouse DNA elements (Mouse ENCODE)

John A Stamatoyannopoulos, Michael Snyder, Ross Hardison, Bing Ren, Thomas Gingeras, David M Gilbert, Mark Groudine, Michael Bender, Rajinder Kaul, Theresa Canfield, Erica Giste, Audra Johnson, Mia Zhang, Gayathri Balasundaram, Rachel Byron, Vaughan Roach, Peter J Sabo, Richard Sandstrom, A Sandra Stehling, Robert E Thurman, Sherman M Weissman, Philip Cayting, Manoj Hariharan, Jin Lian, Yong Cheng, Stephen G Landt, Zhihai Ma, Barbara J Wold, Job Dekker et al. Genome Biology 2012, 13:418 (13 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The Mouse ENCODE Consortium is applying the same experimental pipelines developed for human ENCODE to annotate the mouse genome

12.

Research article   Open Access

Composition and organization of active centromere sequences in complex genomes

Karen E Hayden, Huntington F Willard BMC Genomics 2012, 13:324 (20 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

Review   Open Access

Tissue sampling methods and standards for vertebrate genomics

Pamela BY Wong, Edward O Wiley, Warren E Johnson, Oliver A Ryder, Stephen J O’Brien, David Haussler, Klaus-Peter Koepfli, Marlys L Houck, Polina Perelman, Gabriela Mastromonaco, Andrew C Bentley, Byrappa Venkatesh, Ya-ping Zhang, Robert W Murphy, GigaScience 2012, 1:8 (12 July 2012)

Abstract | Full text | PDF

14.

Research article   Open Access Highly Accessed

Molecular phylogeny of grunts (Teleostei, Haemulidae), with an emphasis on the ecology, evolution, and speciation history of New World species

José Tavera, Arturo P, Eduardo F Balart, Giacomo Bernardi BMC Evolutionary Biology 2012, 12:57 (26 April 2012)

Abstract | Full text | PDF | PubMed

15.

Methodology article   Open Access Highly Accessed

Molecular probe technology detects bacteria without culture

Richard W Hyman, Robert P St Onge, Hyunsung Kim, John S Tamaresis, Molly Miranda, Ana Aparicio, Marilyn Fukushima, Nader Pourmand, Linda C Giudice, Ronald W Davis BMC Microbiology 2012, 12:29 (9 March 2012)

Abstract | Full text | PDF | PubMed

16.

Open letter   Free Highly Accessed

Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes

John A St John, Edward L Braun, Sally R Isberg, Lee G Miles, Amanda Y Chong, Jaime Gongora, Pauline Dalzell, Christopher Moran, Bertrand Bed'Hom, Arkhat Abzhanov, Shane C Burgess, Amanda M Cooksey, Todd A Castoe, Nicholas G Crawford, Llewellyn D Densmore, Jennifer C Drew, Scott V Edwards, Brant C Faircloth, Matthew K Fujita, Matthew J Greenwold, Federico G Hoffmann, Jonathan M Howard, Taisen Iguchi, Daniel E Janes, Shahid Khan, Satomi Kohno, AP Jason de Koning, Stacey L Lance, Fiona M McCarthy, John E McCormack et al. Genome Biology 2012, 13:415 (31 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An Open Letter describing the project to sequence the genomes of the saltwater crocodile, the American alligator and the Indian gharial

17.

Research   Open Access

Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi

Frédéric Landmann, Jeremy M Foster, Barton E Slatko, William Sullivan Parasites & Vectors 2012, 5:16 (13 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This manuscript demonstrates the efficient use of heterogeneous short interfering RNA mixes for performing RNAi in the parasitic nematode Brugia malayi and immunofluorescence-based analysis of cellular phenotypes. Image: Defective 2 cell embryo of Brugia malayi following RNAi targeting the polarity-determining gene, par-1.

18.

Research   Open Access

Robust flash denoising/deblurring by iterative guided filtering

Hae-Jong Seo, Peyman Milanfar EURASIP Journal on Advances in Signal Processing 2012, 2012:3 (6 January 2012)

Abstract | Full text | PDF

19.

Research   Open Access

OpenKnowledge for peer-to-peer experimentation in protein identification by MS/MS

Siu-wai Leung, Xueping Quan, Paolo Besana, Qian Li, Mark Collins, Dietlind Gerloff, Dave Robertson Automated Experimentation 2011, 3:3 (22 December 2011)

Abstract | Full text | PDF | PubMed

20.

Software   Open Access

NanoStriDE: normalization and differential expression analysis of NanoString nCounter data

Christopher D Brumbaugh, Hyunsung J Kim, Mario Giovacchini, Nader Pourmand BMC Bioinformatics 2011, 12:479 (16 December 2011)

Abstract | Full text | PDF | PubMed

21.

Proceedings   Open Access

Prioritizing single-nucleotide variations that potentially regulate alternative splicing

Mingxiang Teng, Yadong Wang, Guohua Wang, Jeesun Jung, Howard J Edenberg, Jeremy R Sanford, Yunlong Liu BMC Proceedings 2011, 5(Suppl 9):S40 (29 November 2011)

Abstract | Full text | PDF

22.

Research   Open Access Highly Accessed

Analysis of induced electrical currents from magnetic field coupling inside implantable neurostimulator leads

Oxana S Pantchenko, Seth J Seidman, Joshua W Guag BioMedical Engineering OnLine 2011, 10:94 (21 October 2011)

Abstract | Full text | PDF | PubMed

23.

Research   Open Access

Electromagnetic compatibility of implantable neurostimulators to RFID emitters

Oxana S Pantchenko, Seth J Seidman, Joshua W Guag, Donald M Witters, Curt L Sponberg BioMedical Engineering OnLine 2011, 10:50 (9 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Primary research   Open Access Highly Accessed

MHC class I-related chain A and B ligands are differentially expressed in human cervical cancer cell lines

Susana del Toro-Arreola, Naela Arreygue-Garcia, Adriana Aguilar-Lemarroy, Angel Cid-Arregui, Miriam Jimenez-Perez, Jesse Haramati, Patricio Barros-Nuñez, Oscar Gonzalez-Ramella, Alicia del Toro-Arreola, Pablo Ortiz-Lazareno, Georgina Hernandez-Flores, Alejandro Bravo-Cuellar, Adrian Daneri-Navarro, Luis F Jave-Suarez Cancer Cell International 2011, 11:15 (1 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Software   Open Access

Meta-Alignment with Crumble and Prune: Partitioning very large alignment problems for performance and parallelization

Krishna M Roskin, Benedict Paten, David Haussler BMC Bioinformatics 2011, 12:144 (10 May 2011)

Abstract | Full text | PDF | PubMed

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