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76.

Research   Open Access

Acute exercise exacerbates ischemia-induced diastolic rigor in hypertensive myocardium

Patricia O Reger, Stephen C Kolwicz, Joseph R Libonati SpringerPlus 2012, 1:46 (2 November 2012)

Abstract | Full text | PDF

77.

Correspondence   Open Access Highly Accessed

“Nonparametric Local Smoothing” is not image registration

Torsten Rohlfing, Brian Avants BMC Research Notes 2012, 5:610 (1 November 2012)

Abstract | Full text | PDF | PubMed

78.

Research article   Open Access

Comorbidities as a driver of the excess costs of community-acquired pneumonia in U.S. commercially-insured working age adults

Daniel Polsky, Machaon Bonafede, Jose A Suaya BMC Health Services Research 2012, 12:379 (31 October 2012)

Abstract | Full text | PDF | PubMed

79.

Research article   Open Access

Cascaded discrimination of normal, abnormal, and confounder classes in histopathology: Gleason grading of prostate cancer

Scott Doyle, Michael D Feldman, Natalie Shih, John Tomaszewski, Anant Madabhushi BMC Bioinformatics 2012, 13:282 (30 October 2012)

Abstract | Full text | PDF | PubMed

80.

Research   Open Access Highly Accessed

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

Hongshuo Song, Jeffrey W Pavlicek, Fangping Cai, Tanmoy Bhattacharya, Hui Li, Shilpa S Iyer, Katharine J Bar, Julie M Decker, Nilu Goonetilleke, Michael KP Liu, Anna Berg, Bhavna Hora, Mark S Drinker, Josh Eudailey, Joy Pickeral, M Moody, Guido Ferrari, Andrew McMichael, Alan S Perelson, George M Shaw, Beatrice H Hahn, Barton F Haynes, Feng Gao Retrovirology 2012, 9:89 (30 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper reveals a broad spectrum of fitness costs to CTL escape mutations in HIV-1l genomes, similar to recent findings reported for neutralizing antibody escape mutations. The findings highlight the extraordinary plasticity and adaptive potential of the HIV-1 genome.

81.

Research   Open Access

Cost of palliative radiation to the bone for patients with bone metastases secondary to breast or prostate cancer

Gregory Hess, Arie Barlev, Karen Chung, Jerrold W Hill, Eileen Fonseca Radiation Oncology 2012, 7:168 (12 October 2012)

Abstract | Full text | PDF | PubMed

82.

Short report   Open Access Highly Accessed

HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells

Rik Schrijvers, Sofie Vets, Jan De Rijck, Nirav Malani, Frederic D Bushman, Zeger Debyser, Rik Gijsbers Retrovirology 2012, 9:84 (9 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

HRP-2 overexpression can compensate for the absence of LEDGF/p75 and indicate that the residual bias in integration targeting observed in the absence of LEDGF/p75 can be ascribed to HRP-2. Knockdown of HRP-2 upon LEDGF/p75 depletion results in a more random HIV-1 integration pattern.

83.

Review   Open Access Highly Accessed

Sex differences in microRNA regulation of gene expression: no smoke, just miRs

Christopher P Morgan, Tracy L Bale Biology of Sex Differences 2012, 3:22 (26 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

84.

Research   Open Access

Early data from project engage: a program to identify and transition medically hospitalized patients into addictions treatment

Anna Pecoraro, Terry Horton, Edward Ewen, Julie Becher, Patricia A Wright, Basha Silverman, Patty McGraw, George E Woody Addiction Science & Clinical Practice 2012, 7:20 (25 September 2012)

Abstract | Full text | PDF | PubMed

85.

Research article   Open Access Highly Accessed

Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23

Jianhua Zhao, Sandra Deliard, Ali Aziz, Struan FA Grant BMC Medical Genetics 2012, 13:89 (24 September 2012)

Abstract | Full text | PDF | PubMed

86.

Research article   Open Access

Shared decision making and behavioral impairment: a national study among children with special health care needs

Alexander G Fiks, Stephanie Mayne, A Localio, Chris Feudtner, Evaline A Alessandrini, James P Guevara BMC Pediatrics 2012, 12:153 (21 September 2012)

Abstract | Full text | PDF | PubMed

87.

Commentary   Open Access Highly Accessed

The dendritic cell niche in chronic obstructive pulmonary disease

Angela Haczku Respiratory Research 2012, 13:80 (19 September 2012)

Abstract | Full text | PDF | PubMed

88.

Review   Open Access Highly Accessed

Care of the injured worldwide: trauma still the neglected disease of modern society

Joseph V Sakran, Sarah E Greer, Evan Werlin, Maureen McCunn Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:64 (15 September 2012)

Abstract | Full text | PDF | PubMed

89.

Poster presentation   Open Access

E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost

NA Hutnick, M Karuppiah, J Pollara, J Yan, DJ Myles, K Broderick, M Morrow, N Sardasai, D Montefiori, S Barnett, G Ferrari, DB Weiner Retrovirology 2012, 9(Suppl 2):P364 (13 September 2012)

Full text | PDF

90.

Poster presentation   Open Access

2G12/PGT-binding yeast glycoprotein Gp38 elicits mannose-specific HIV-1 Env cross-reactive antibodies

H Zhang, H Fu, B Liu, RJ Luallen, RW Doms, DF Smith, Y Geng Retrovirology 2012, 9(Suppl 2):P357 (13 September 2012)

Full text | PDF

91.

Poster presentation   Open Access

Comparison of cellular and humoral immune responses induced by primary, consensus or mosaic HIV-1 Env DNA vaccines

J Yan, P Pankhong, AS Khan, NY Sardesai, DB Weiner Retrovirology 2012, 9(Suppl 2):P333 (13 September 2012)

Full text | PDF

92.

Poster presentation   Open Access

Increased mucosal CD4+ T-cell activation following vaccination with an adenoviral vector in rhesus macaques

I Bukh, R Calcedo, S Roy, DG Carnathan, R Grant, SJ Ratcliffe, JM Wilson, MR Betts Retrovirology 2012, 9(Suppl 2):P267 (13 September 2012)

Full text | PDF

93.

Poster presentation   Open Access

Improved systemic and mucosal antibody responses with a CCR10 ligand adjuvant

N Hutnick, DJ Myles, A Ginsberg, AS Khan, J Yan, Z Moldoveanu, J Mestecky, PA Marx, M Kutzler, DB Weiner Retrovirology 2012, 9(Suppl 2):P203 (13 September 2012)

Full text | PDF

94.

Poster presentation   Open Access

Postnatally-transmitted HIV-1 variants are efficient at dendritic cell trans-infection and sensitive to autologous and heterologous neutralization

GG Fouda, T Mahlokozera, K Rizzolo, J Salazar-Gonzalez, M Salazar, G Learn, S Barotra, M Sekaran, E Russell, F Jaeger, F Cai, F Gao, B Hahn, R Swanstrom, S Meshnick, V Mwapasa, L Kalilani, S Fiscus, D Montefiori, B Haynes, J Kwiek, M Alam, S Permar Retrovirology 2012, 9(Suppl 2):P148 (13 September 2012)

Full text | PDF

95.

Poster presentation   Open Access

Incident cases characterization and deep sequencing provide new insight into multiplicity of infection and HIV evolution in very early acute infection

G Kijak, E Sanders-Buell, M Rolland, H Li, A Bates, M Bose, A O'Sullivan, L Eller, R O'Connell, G Shaw, N Michael, J Kim, M Robb, S Tovanabutra Retrovirology 2012, 9(Suppl 2):P143 (13 September 2012)

Full text | PDF

96.

Poster presentation   Open Access

First-in-human phase I clinical trial of a recombinant vesicular stomatitis virus (rVSV)-based preventive HIV-1 vaccine

JD Fuchs, I Frank, N Kochar, M Elizaga, M Allen, D Carter, N Frahm, SA Kalams, M Mulligan, R Sheets, M Pensiero, D Clarke, J Eldridge Retrovirology 2012, 9(Suppl 2):P134 (13 September 2012)

Full text | PDF

97.

Poster presentation   Open Access

Feasibility of recruiting high-risk women in the US for HIV vaccine efficacy trials (HVTN 906)

B Koblin, B Metch, C Morgan, R Novak, E Swann, D Metzger, D Lucy, D Dunbar, P Graham, T Madenwald, G Escamia, I Frank Retrovirology 2012, 9(Suppl 2):P123 (13 September 2012)

Full text | PDF

98.

Poster presentation   Open Access

Using an internet consumer marketing strategy to reach men who have sex with men for participation in a preventive HIV vaccine clinical trial

CD Voytek, KT Jones, BL Curtis, DT Fiore, D Dunbar, I Frank, DS Metzger, Retrovirology 2012, 9(Suppl 2):P119 (13 September 2012)

Full text | PDF

99.

Oral presentation   Open Access

DNA vaccines expressing conserved elements provide potent and broad immune responses

GN Pavlakis, V Kulkarni, A Valentin, M Rosati, NY Sardesai, B Mothe, C Brander, S LeGall, DB Weiner, M Rolland, JI Mullins, BK Felber Retrovirology 2012, 9(Suppl 2):O67 (13 September 2012)

Full text | PDF

100.

Oral presentation   Open Access

Distinct gene expression profiles associated with the susceptibility of pathogen-specific CD4+ T cells to HIV-1 infection

H Hu, M Nau, P Ehrenberg, A Chenine, Z Daye, Z Wei, N Michael, M Vahey, J Kim, M Marovich, S Ratto-Kim Retrovirology 2012, 9(Suppl 2):O46 (13 September 2012)

Full text | PDF

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