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76.

Research   Open Access Highly Accessed

Creating a honey bee consensus gene set

Christine G Elsik, Aaron J Mackey, Justin T Reese, Natalia V Milshina, David S Roos, George M Weinstock Genome Biology 2007, 8:R13 (22 January 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A high-quality consensus gene set for the honey bee (Apis mellifera) created using a new algorithm (GLEAN) is described.

77.

Research article   Open Access

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Antonis C Antoniou, Karoline B Kuchenbaecker, Penny Soucy, Jonathan Beesley, Xiaoqing Chen, Lesley McGuffog, Andrew Lee, Daniel Barrowdale, Sue Healey, Olga M Sinilnikova, Maria A Caligo, Niklas Loman, Katja Harbst, Annika Lindblom, Brita Arver, Richard Rosenquist, Per Karlsson, Kate Nathanson, Susan Domchek, Tim Rebbeck, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Elżbieta Złowowcka-Perłowska, Ana Osorio, Mercedes Durán, Raquel Andrés, Javier Benítez, Ute Hamann et al. Breast Cancer Research 2012, 14:R33 (20 February 2012)

Abstract | Full text | PDF | PubMed

78.

Research   Open Access Highly Accessed

Evidence in the learning organization

Gerald E Crites, Megan C McNamara, Elie A Akl, W Scott Richardson, Craig A Umscheid, James Nishikawa Health Research Policy and Systems 2009, 7:4 (26 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

79.

Review   Open Access Highly Accessed

The National Cancer Institute Thyroid fine needle aspiration state of the science conference: a summation

Zubair W Baloch, Edmund S Cibas, Douglas P Clark, Lester J Layfield, Britt-Marie Ljung, Martha Pitman, Andrea Abati CytoJournal 2008, 5:6 (7 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

80.

Research article   Open Access Highly Accessed

DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Nahid Turan, Mohamed F Ghalwash, Sunita Katari, Christos Coutifaris, Zoran Obradovic, Carmen Sapienza BMC Medical Genomics 2012, 5:10 (12 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.

81.

Review   Free Highly Accessed

Strategies to optimize analgesia and sedation

William D Schweickert, John P Kress Critical Care 2008, 12(Suppl 3):S6 (14 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

82.

Review   Open Access

Monogenic hyperinsulinemic hypoglycemia: current insights into the pathogenesis and management

Katherine Lord, Diva D De León International Journal of Pediatric Endocrinology 2013, 2013:3 (6 February 2013)

Abstract | Full text | PDF | PubMed

83.

Research article   Open Access

Prevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators

Sergey Yaklichkin, Alexander Vekker, Steven Stayrook, Mitchell Lewis, Daniel S Kessler BMC Genomics 2007, 8:201 (28 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

84.

Review   Open Access Highly Accessed

Sex differences in microRNA regulation of gene expression: no smoke, just miRs

Christopher P Morgan, Tracy L Bale Biology of Sex Differences 2012, 3:22 (26 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

85.

Research   Open Access Highly Accessed

The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation

Dong Xia, Sanya J Sanderson, Andrew R Jones, Judith H Prieto, John R Yates, Elizabeth Bromley, Fiona M Tomley, Kalpana Lal, Robert E Sinden, Brian P Brunk, David S Roos, Jonathan M Wastling Genome Biology 2008, 9:R116 (21 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A proteomics analysis identifies one third of the predicted Toxoplasma gondii proteins and integrates proteomics and genomics data to refine genome annotation.

86.

Commentary   Open Access Highly Accessed

A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB

Tim F Rayner, Philippe Rocca-Serra, Paul T Spellman, Helen C Causton, Anna Farne, Ele Holloway, Rafael A Irizarry, Junmin Liu, Donald S Maier, Michael Miller, Kjell Petersen, John Quackenbush, Gavin Sherlock, Christian J Stoeckert, Joseph White, Patricia L Whetzel, Farrell Wymore, Helen Parkinson, Ugis Sarkans, Catherine A Ball, Alvis Brazma BMC Bioinformatics 2006, 7:489 (6 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A new spreadsheet-based format for microarray data, MAGE-TAB, is simple to use and fully compliant with MIAME and MAGE-ML standards making it very suitable for labs without bioinformatics expertise.

87.

Research   Open Access

Agricultural chemical exposures and birth defects in the Eastern Cape Province, South Africa A case – control study

Gudrun A Heeren, Joanne Tyler, Andrew Mandeya Environmental Health: A Global Access Science Source 2003, 2:11 (4 October 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

88.

Research article   Open Access Highly Accessed

GAGE: generally applicable gene set enrichment for pathway analysis

Weijun Luo, Michael S Friedman, Kerby Shedden, Kurt D Hankenson, Peter J Woolf BMC Bioinformatics 2009, 10:161 (27 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

89.

Research article   Open Access Highly Accessed

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

Julia Tchou, Andrew V Kossenkov, Lisa Chang, Celine Satija, Meenhard Herlyn, Louise C Showe, Ellen Puré BMC Medical Genomics 2012, 5:39 (6 September 2012)

Abstract | Full text | PDF | PubMed

90.

Research   Open Access

Overview of BioCreative II gene mention recognition

Larry Smith, Lorraine K Tanabe, Rie Ando, Cheng-Ju Kuo, I-Fang Chung, Chun-Nan Hsu, Yu-Shi Lin, Roman Klinger, Christoph M Friedrich, Kuzman Ganchev, Manabu Torii, Hongfang Liu, Barry Haddow, Craig A Struble, Richard J Povinelli, Andreas Vlachos, William A Baumgartner, Lawrence Hunter, Bob Carpenter, Richard Tsai, Hong-Jie Dai, Feng Liu, Yifei Chen, Chengjie Sun, Sophia Katrenko, Pieter Adriaans, Christian Blaschke, Rafael Torres, Mariana Neves, Preslav Nakov, Anna Divoli, Manuel Maña-López, Jacinto Mata, W John Wilbur et al. Genome Biology 2008, 9(Suppl 2):S2 (1 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

91.

Research article   Open Access Highly Accessed

Accurate microRNA target prediction correlates with protein repression levels

Manolis Maragkakis, Panagiotis Alexiou, Giorgio L Papadopoulos, Martin Reczko, Theodore Dalamagas, George Giannopoulos, George Goumas, Evangelos Koukis, Kornilios Kourtis, Victor A Simossis, Praveen Sethupathy, Thanasis Vergoulis, Nectarios Koziris, Timos Sellis, Panagiotis Tsanakas, Artemis G Hatzigeorgiou BMC Bioinformatics 2009, 10:295 (18 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

92.

Research   Open Access Highly Accessed

Many LINE1 elements contribute to the transcriptome of human somatic cells

Sanjida H Rangwala, Lili Zhang, Haig H Kazazian Genome Biology 2009, 10:R100 (22 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Over 600 LINE 1 elements are shown to be transcribed in humans; 400 of these are full-length elements in the reference genome.

93.

Review   Open Access Highly Accessed

Emerging role of radiolabeled nanoparticles as an effective diagnostic technique

AndréLuís de Barros, Andrew Tsourkas, Babak Saboury, Valbert Cardoso, Abass Alavi EJNMMI Research 2012, 2:39 (18 July 2012)

Abstract | Full text | PDF | PubMed

94.

Study protocol   Open Access Highly Accessed

The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes: A cohort study: trial protocol

Gavin D Perkins, Robin P Davies, Sarah Quinton, Sarah Woolley, Fang Gao, Ben Abella, Nigel Stallard, Matthew W Cooke, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2011, 19:58 (18 October 2011)

Abstract | Full text | PDF | PubMed

95.

Research   Open Access

Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation

Erica L Carpenter, Rosemarie Mick, Jens Rüter, Robert H Vonderheide Journal of Translational Medicine 2009, 7:93 (11 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

96.

Research   Open Access

IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells

Saskia JAM Santegoets, Annelies W Turksma, Megan M Suhoski, Anita GM Stam, Steve M Albelda, Erik Hooijberg, Rik J Scheper, Alfons JM van den Eertwegh, Winald R Gerritsen, Daniel J Powell, Carl H June, Tanja D de Gruijl Journal of Translational Medicine 2013, 11:37 (12 February 2013)

Abstract | Full text | PDF | PubMed

97.

Research   Open Access

An endogenous F-box protein regulates ARGONAUTE1 in Arabidopsis thaliana

K Earley, MR Smith, R Weber, BD Gregory, RS Poethig Silence 2010, 1:15 (12 July 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An endogenous F-box protein negatively regulates the protein levels of ARGONAUTE1, a core component of the RNA-induced silencing complex, and affects the sensitivity of plants to the growth regulator abscisic acid.

98.

Research article   Open Access

Stat and interferon genes identified by network analysis differentially regulate primitive and definitive erythropoiesis

Emily Greenfest-Allen, Jeffrey Malik, James Palis, Christian J Stoeckert BMC Systems Biology 2013, 7:38 (15 May 2013)

Abstract | Provisional PDF

99.

Research   Open Access

Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins

Gary LeRoy, Iouri Chepelev, Peter A DiMaggio, Mario A Blanco, Barry M Zee, Keji Zhao, Benjamin A Garcia Genome Biology 2012, 13:R68 (16 August 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

A novel proteogenomic strategy links the histone reader proteins Brd3 and Brd4 to HOX gene regulation

100.

Research   Open Access

Researchers’ perceptions of ethical challenges in cluster randomized trials: a qualitative analysis

Andrew D McRae, Carol Bennett, Judith Belle Brown, Charles Weijer, Robert Boruch, Jamie Brehaut, Shazia Chaudhry, Allan Donner, Martin Eccles, Jeremy Grimshaw, Merrick Zwarenstein, Monica Taljaard Trials 2013, 14:1 (3 January 2013)

Abstract | Full text | PDF | PubMed

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