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1.

Research   Open Access

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

Roland F Hoffmann, Sina Zarrintan, Simone M Brandenburg, Arjan Kol, Harold G de Bruin, Shabnam Jafari, Freark Dijk, Dharamdajal Kalicharan, Marco Kelders, Harry R Gosker, Nick HT ten Hacken, Johannes J van der Want, Antoon JM van Oosterhout, Irene H Heijink Respiratory Research 2013, 14:97 (2 October 2013)

Abstract | Provisional PDF

2.

Review   Open Access

Exergaming for balance training of elderly: state of the art and future developments

Mike Van Diest, Claudine JC Lamoth, Jan Stegenga, Gijsbertus J Verkerke, Klaas Postema Journal of NeuroEngineering and Rehabilitation 2013, 10:101 (25 September 2013)

Abstract | Provisional PDF | PubMed

3.

Research   Open Access

Aggravation of myocardial dysfunction by injurious mechanical ventilation in LPS-induced pneumonia in rats

Lonneke Smeding, Jan Kuiper, Frans B Plötz, Martin CJ Kneyber, AB Groeneveld Respiratory Research 2013, 14:92 (18 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase

Johannes Hofland, Leo J Hofland, Peter M van Koetsveld, Jacobie Steenbergen, Wouter W de Herder, Casper H van Eijck, Ronald R de Krijger, Francien H van Nederveen, Maarten O van Aken, Johannes W de Groot, Thera P Links, Frank H de Jong, Richard A Feelders Orphanet Journal of Rare Diseases 2013, 8:142 (13 September 2013)

Abstract | Full text | PDF | PubMed

5.

Commentary   Open Access

Diagnostic heterogeneity in psychiatry: towards an empirical solution

Klaas J Wardenaar, Peter de Jonge BMC Medicine 2013, 11:201 (12 September 2013)

Abstract | Full text | PDF |  Editor’s summary

Given the current challenges in psychiatric medicine, Klaas Wardenaar and Peter de Jonge argue that evidence-based diagnostic methods should be developed by using multimode analysis and modelling to assess heterogeneity across persons and symptoms over time, to accurately identify optimal homogeneous subgroups.

6.

Research article   Open Access

Androgen deficiency in male patients diagnosed with ANCA-associated vasculitis: a cause of fatigue and reduced health-related quality of life?

Janneke Tuin, Jan-Stephan F Sanders, Birgit M Buhl, André P van Beek, Coen A Stegeman Arthritis Research & Therapy 2013, 15:R117 (12 September 2013)

Abstract | Provisional PDF | PubMed

7.

Research   Open Access Highly Accessed

Algorithm for pre-emptive glycopeptide treatment in patients with haematologic malignancies and an Enterococcus faecium bloodstream infection

Xuewei Zhou, Jan P Arends, Lambert FR Span, Alexander W Friedrich Antimicrobial Resistance and Infection Control 2013, 2:24 (11 September 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access Highly Accessed

Quality of life in dementia: a study on proxy bias

Alexander MM Arons, Paul FM Krabbe, Carla JM Schölzel-Dorenbos, Gert van der Wilt, Marcel GM Rikkert BMC Medical Research Methodology 2013, 13:110 (6 September 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Phenylketonuria: reduced tyrosine brain influx relates to reduced cerebral protein synthesis

Martijn J de Groot, Marieke Hoeksma, Dirk-Jan Reijngoud, Harold W de Valk, Anne MJ Paans, Pieter JJ Sauer, Francjan J van Spronsen Orphanet Journal of Rare Diseases 2013, 8:133 (4 September 2013)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access

Associations between smoking, components of metabolic syndrome and lipoprotein particle size

Sandra N Slagter, Jana Vliet-Ostaptchouk, Judith M Vonk, H Boezen, Robin PF Dullaart, Anneke C Muller Kobold, Edith J Feskens, André Beek, Melanie Klauw, Bruce HR Wolffenbuttel BMC Medicine 2013, 11:195 (3 September 2013)

Abstract | Full text | PDF |  Editor’s summary

Smoking is associated with increased prevalence of metabolic syndrome irrespective of sex or body mass index, and the association is related to lipid changes, providing a mechanism linking smoking to increased risk of cardiovascular disease.

11.

Correction   Open Access

Correction: Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy

Joris van Ark, Hans-Peter Hammes, Marcory CRF van Dijk, Chris PH Lexis, Iwan CC van der Horst, Clark J Zeebregts, Marc G Vervloet, Bruce HR Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands Cardiovascular Diabetology 2013, 12:120 (28 August 2013)

Full text | PDF | PubMed

12.

Research article   Open Access

ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

Blanca E Himes, Weiliang Qiu, Barbara Klanderman, John Ziniti, Jody Senter-Sylvia, Stanley J Szefler, Robert F Lemanske, Jr, Robert S Zeiger, Robert C Strunk, Fernando D Martinez, Homer Boushey, Vernon M Chinchilli, Elliot Israel, David Mauger, Gerard H Koppelman, Maartje AE Nieuwenhuis, Dirkje S Postma, Judith M Vonk, Nicholas Rafaels, Nadia N Hansel, Kathleen Barnes, Benjamin Raby, Kelan G Tantisira, Scott T Weiss BMC Medical Genetics 2013, 14:86 (28 August 2013)

Abstract | Full text | PDF | PubMed

13.

Research article   Open Access

Which patient and treatment factors are related to successful cardiovascular risk score reduction in general practice? Results from a randomized controlled trial

Ans H Tiessen, Andries J Smit, Jan Broer, Klaas H Groenier, Klaas Van der Meer BMC Family Practice 2013, 14:123 (23 August 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Multidimensional structure of the Groningen Frailty Indicator in community-dwelling older people

Annemiek Bielderman, Cees P van der Schans, Marie-Rose J van Lieshout, Mathieu HG de Greef, Froukje Boersma, Wim P Krijnen, Nardi Steverink BMC Geriatrics 2013, 13:86 (22 August 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access

Life changes and depressive symptoms: the effects of valence and amount of change

Elise C Bennik, Johan Ormel, Albertine J Oldehinkel BMC Psychology 2013, 1:14 (21 August 2013)

Abstract | Full text | PDF

16.

Original investigation   Open Access

Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy

Joris van Ark, Hans-Peter Hammes, Marcory C R F van Dijk, Marc G Vervloet, Bruce H R Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands Cardiovascular Diabetology 2013, 12:116 (14 August 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Study protocol   Open Access

Implementation of the Participatory Approach to increase supervisors’ self-efficacy in supporting employees at risk for sick leave; design of a randomised controlled trial

Ruben A Kraaijeveld, Frederieke G Schaafsma, Cécile RL Boot, William S Shaw, Ute Bültmann, Johannes R Anema BMC Public Health 2013, 13:750 (13 August 2013)

Abstract | Full text | PDF | PubMed

18.

Original research   Open Access Highly Accessed

Optimized dose regimen for whole-body FDG-PET imaging

Eleonore H de Groot, Nieky Post, Ronald Boellaard, Nils RL Wagenaar, Antoon TM Willemsen, Jorn A van Dalen EJNMMI Research 2013, 3:63 (12 August 2013)

Abstract | Full text | PDF | PubMed

19.

Research   Open Access

GST-omega genes interact with environmental tobacco smoke on adult level of lung function

Kim de Jong, H Boezen, Nick HT ten Hacken, Dirkje S Postma, Judith M Vonk, Respiratory Research 2013, 14:83 (9 August 2013)

Abstract | Full text | PDF | PubMed

20.

Research article   Open Access Highly Accessed

Variability of antibiotic susceptibility and toxin production of Staphylococcus aureus strains isolated from skin, soft tissue, and bone related infections

Haziz Sina, Théodora A Ahoyo, Wardi Moussaoui, Daniel Keller, Honoré S Bankolé, Yves Barogui, Ymkje Stienstra, Simeon O Kotchoni, Gilles Prévost, Lamine Baba-Moussa BMC Microbiology 2013, 13:188 (8 August 2013)

Abstract | Full text | PDF | PubMed

21.

Study protocol   Open Access

Levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation (Novasure) in women with heavy menstrual bleeding: a multicentre randomised controlled trial

Malou C Herman, Marian J van den Brink, Peggy M Geomini, Hannah S van Meurs, Judith A Huirne, Heleen P Eising, Anne Timmermans, Johanna MA Pijnenborg, Ellen R Klinkert, Sjors F Coppus, Theodoor E Nieboer, Ruby Catshoek, Lucet F van der Voet, Hugo WF van Eijndhoven, Giuseppe CM Graziosi, Sebastiaan Veersema, Paul J van Kesteren, Josje Langenveld, Nicol AC Smeets, Huib AAM van Vliet, Jan van der Steeg, Yvonne Lisman-van Leeuwen, Janny H Dekker, Ben W Mol, Marjolein Y Berger, Marlies Y Bongers BMC Women's Health 2013, 13:32 (8 August 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Ursodeoxycholic acid counteracts celecoxib in reduction of duodenal polyps in patients with familial adenomatous polyposis: a multicentre, randomized controlled trial

Bjorn WH van Heumen, Hennie MJ Roelofs, M Vink-Börger, Evelien Dekker, Elisabeth MH Mathus-Vliegen, Jan Dees, Jan J Koornstra, Alexandra MJ Langers, Iris D Nagtegaal, Ellen Kampman, Wilbert HM Peters, Fokko M Nagengast, Orphanet Journal of Rare Diseases 2013, 8:118 (6 August 2013)

Abstract | Full text | PDF | PubMed

23.

Original research   Open Access

18F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study

Kimy M Emonds, Michel Koole, Cindy Casteels, Laura Van den Bergh, Guy M Bormans, Filip Claus, Liesbeth De Wever, Evelyne Lerut, Hendrik Van Poppel, Steven Joniau, Herlinde Dumez, Karin Haustermans, Luc Mortelmans, Karolien Goffin, Koen Van Laere, Christophe M Deroose, Felix M Mottaghy EJNMMI Research 2013, 3:59 (2 August 2013)

Abstract | Full text | PDF | PubMed

24.

Short report   Open Access

Genetic incompatibility drives mate choice in a parasitic wasp

Andra Thiel, Anne C Weeda, Jetske G de Boer, Thomas S Hoffmeister Frontiers in Zoology 2013, 10:43 (30 July 2013)

Abstract | Full text | PDF | PubMed

25.

Study protocol   Open Access

The NLstart2run study: health effects of a running promotion program in novice runners, design of a prospective cohort study

Bas Kluitenberg, Marienke van Middelkoop, Ron L Diercks, Fred Hartgens, Evert Verhagen, Dirk-Wouter Smits, Ida Buist, Henk van der Worp BMC Public Health 2013, 13:685 (26 July 2013)

Abstract | Full text | PDF | PubMed

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