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1.

Research article   Open Access

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Suzanne A Eccles, Eric O Aboagye, Simak Ali, Annie S Anderson, Jo Armes, Fedor Berditchevski, Jeremy P Blaydes, Keith Brennan, Nicola J Brown, Helen E Bryant, Nigel J Bundred, Joy M Burchell, Anna M Campbell, Jason S Carroll, Robert B Clarke, Charlotte E Coles, Gary JR Cook, Angela Cox, Nicola J Curtin, Lodewijk V Dekker, Isabel dos Santos Silva, Stephen W Duffy, Douglas F Easton, Diana M Eccles, Dylan R Edwards, Joanne Edwards, D Evans, Deborah F Fenlon, James M Flanagan, Claire Foster et al. Breast Cancer Research 2013, 15:R92 (1 October 2013)

Abstract | Full text | PDF |  Editor’s summary

Current knowledge 'gaps' in the understanding of breast cancer are examined, and research should focus on these to improve future clinical care.

2.

Research   Open Access

How reliable is the linear noise approximation of gene regulatory networks?

Philipp Thomas, Hannes Matuschek, Ramon Grima BMC Genomics 2013, 14(Suppl 4):S5 (1 October 2013)

Abstract | Full text | PDF

3.

Research   Open Access

Cattle movements and trypanosomes: restocking efforts and the spread of Trypanosoma brucei rhodesiense sleeping sickness in post-conflict Uganda

Richard Selby, Kevin Bardosh, Kim Picozzi, Charles Waiswa, Susan C Welburn Parasites & Vectors 2013, 6:281 (27 September 2013)

Abstract | Provisional PDF |  Editor’s summary

As demand for draft oxen (predominately Zebu cattle) and private cattle trading continues from endemic to pathogen-free areas of northern Uganda, treatment at market is essential to limit the continued expansion of the T. b. rhodesiense focus and prevent the potential overlap with the Gambian sleeping sickness focus. Although implementation of effective zoonotic disease control in resource-poor areas may appear challenging, the costs of neglecting to prevent the future spread of T. b. rhodesiense will be much higher. Image: Demand for draft oxen is high in post- conflict Uganda - Proud farmer and Prize Ox

4.

Research article   Open Access

Identification of genes expressed in the sex pheromone gland of the black cutworm Agrotis ipsilon with putative roles in sex pheromone biosynthesis and transport

Shao-Hua Gu, Kong-Ming Wu, Yu-Yuan Guo, John A Pickett, Linda M Field, Jing-Jiang Zhou, Yong-Jun Zhang BMC Genomics 2013, 14:636 (22 September 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

An expression atlas of human primary cells: inference of gene function from coexpression networks

Neil A Mabbott, J Baillie, Helen Brown, Tom C Freeman, David A Hume BMC Genomics 2013, 14:632 (20 September 2013)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access

Breastfeeding for reducing the risk of pneumonia morbidity and mortality in children under two: a systematic literature review and meta-analysis

Laura M Lamberti, Irena Zakarija-Grković, Christa L Fischer Walker, Evropi Theodoratou, Harish Nair, Harry Campbell, Robert E Black BMC Public Health 2013, 13(Suppl 3):S18 (17 September 2013)

Abstract | Full text | PDF

7.

Review   Open Access

An evaluation of the emerging vaccines against influenza in children

Harish Nair, Eva Lau, W Brooks, Ang Seong, Evropi Theodoratou, Lina Zgaga, Tanvir Huda, Suresh S Jadhav, Igor Rudan, Harry Campbell BMC Public Health 2013, 13(Suppl 3):S14 (17 September 2013)

Abstract | Full text | PDF

8.

Study protocol   Open Access

Muslim communities learning about second-hand smoke (MCLASS): study protocol for a pilot cluster randomised controlled trial

Hannah Ainsworth, Sarwat Shah, Faraz Ahmed, Amanda Amos, Ian Cameron, Caroline Fairhurst, Rebecca King, Ghazala Mir, Steve Parrott, Aziz Sheikh, David Torgerson, Heather Thomson, Kamran Siddiqi Trials 2013, 14:295 (13 September 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

Splice site SNPs of phospholipase PLCXD3 are significantly associated with variant and sporadic Creutzfeldt-Jakob disease

Matthew T Bishop, Pascual Sanchez-Juan, Richard SG Knight BMC Medical Genetics 2013, 14:91 (12 September 2013)

Abstract | Full text | PDF | PubMed

10.

Study protocol   Open Access

Goal-setting intervention in patients with active asthma: protocol for a pilot cluster-randomised controlled trial

Gaylor Hoskins, Purva Abhyankar, Anne D Taylor, Edward Duncan, Aziz Sheikh, Hilary Pinnock, Marjon van der Pol, Peter T Donnan, Brian Williams Trials 2013, 14:289 (11 September 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla --selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

Peter Simmonds, Wenjun Xia, J Kenneth Baillie, Ken McKinnon BMC Genomics 2013, 14:610 (10 September 2013)

Abstract | Provisional PDF | PubMed

12.

Research article   Open Access Highly Accessed

Mortality in East African shorthorn zebu cattle under one year: predictors of infectious-disease mortality

Samuel M Thumbi, Mark Bronsvoort, Henry Kiara, PG Toye, Jane Poole, Mary Ndila, Ilana Conradie, Amy Jennings, Ian G Handel, JAW Coetzer, Johan Steyl, Olivier Hanotte, Mark EJ Woolhouse BMC Veterinary Research 2013, 9:175 (8 September 2013)

Abstract | Full text | PDF | PubMed

13.

Methodology   Open Access

Study of therapeutic hypothermia (32 to 35°C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial): outcome of the pilot phase of the trial

Peter J D Andrews, Louise H Sinclair, Bridget Harris, Melissa J Baldwin, Claire G Battison, Jonathan K J Rhodes, Gordon Murray, Daniel De Backer, Trials 2013, 14:277 (3 September 2013)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access

A UK validation of a general measure of subjective well-being: the modified BBC subjective well-being scale (BBC-SWB)

Eleanor Pontin, Matthias Schwannauer, Sara Tai, Peter Kinderman Health and Quality of Life Outcomes 2013, 11:150 (3 September 2013)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access Highly Accessed

On estimation of genetic variance within families using genome-wide identity-by-descent sharing

William G Hill Genetics Selection Evolution 2013, 45:32 (3 September 2013)

Abstract | Provisional PDF | PubMed

16.

Research article   Open Access

Design and descriptive epidemiology of the Infectious Diseases of East African Livestock (IDEAL) project, a longitudinal calf cohort study in western Kenya

Barend de Clare Bronsvoort, Samuel Thumbi, Elizabeth Poole, Henry Kiara, Olga Auguet, Ian Handel, Amy Jennings, Ilana Conradie, Mary Mbole-Kariuki, Philip G Toye, Olivier Hanotte, JAW Coetzer, Mark EJ Woolhouse BMC Veterinary Research 2013, 9:171 (30 August 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Research article   Open Access

The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide

Ronan Kapetanovic, Lynsey Fairbairn, Alison Downing, Dario Beraldi, David P Sester, Tom C Freeman, Christopher K Tuggle, Alan L Archibald, David A Hume BMC Genomics 2013, 14:581 (28 August 2013)

Abstract | Full text | PDF | PubMed

18.

Short Report   Open Access

EMAP/EMAPA ontology of mouse developmental anatomy: 2013 update

Terry F Hayamizu, Michael N Wicks, Duncan R Davidson, Albert Burger, Martin Ringwald, Richard A Baldock Journal of Biomedical Semantics 2013, 4:15 (26 August 2013)

Abstract | Provisional PDF | PubMed

19.

Research   Open Access

Suppression of ovine lymphocyte activation by Teladorsagia circumcincta larval excretory-secretory products

Tom N McNeilly, Mara Rocchi, Yvonne Bartley, Jeremy K Brown, David Frew, Cassandra Longhi, Louise McLean, Jenni McIntyre, Alasdair J Nisbet, Sean Wattegedera, John F Huntley, Jacqueline B Matthews Veterinary Research 2013, 44:70 (21 August 2013)

Abstract | Full text | PDF | PubMed

20.

Research article   Open Access Highly Accessed

Mapping the sex determination locus in the Atlantic halibut (Hippoglossus hippoglossus) using RAD sequencing

Christos Palaiokostas, Michaël Bekaert, Andrew Davie, Mairi E Cowan, Münevver Oral, John B Taggart, Karim Gharbi, Brendan J McAndrew, David J Penman, Hervé Migaud BMC Genomics 2013, 14:566 (20 August 2013)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access Highly Accessed

Hydrogen ion concentration and coronary artery bypass graft surgery with and without cardiopulmonary bypass

Cher Chuah, Rachael Kirkbride, R Alston, Joanne Irons Journal of Cardiothoracic Surgery 2013, 8:184 (20 August 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

A longitudinal survey of African animal trypanosomiasis in domestic cattle on the Jos Plateau, Nigeria: prevalence, distribution and risk factors

Ayodele O Majekodunmi, Akinyemi Fajinmi, Charles Dongkum, Kim Picozzi, Michael V Thrusfield, Susan C Welburn Parasites & Vectors 2013, 6:239 (19 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper investigated the epidemiology of African Animal Trypanosomiasis in cattle on the Jos Plateau, Nigeria, and describes the prevalence and distribution of the disease, as well as risk factors for infection. Image: Fulani pastoralist and calf, Jos Plateau, Nigeria.

23.

Meeting abstract   Open Access

Comparative analysis of breast and colorectal tumours uncouples loss of DNA methylation in cancer from association with the nuclear periphery

Elizabeth Kerr, Richard R Meehan, Wendy A Bickmore, Duncan Sproul Clinical Epigenetics 2013, 5(Suppl 1):S8 (19 August 2013)

Full text | PDF

24.

Research article   Open Access Highly Accessed

Identifying potential RNAi targets in grain aphid (Sitobion avenae F.) based on transcriptome profiling of its alimentary canal after feeding on wheat plants

Min Zhang, Yuwen Zhou, Hui Wang, Huw Jones, Qiang Gao, Dahai Wang, Youzhi Ma, Lanqin Xia BMC Genomics 2013, 14:560 (16 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Transcriptome profiling of wheat aphid alimentary canal identifies 5 novel and effective target genes for potential aphid control in wheat through a plant-mediated RNA interference (RNAi) strategy.

25.

Software   Open Access Highly Accessed

ArkMAP: integrating genomic maps across species and data sources

Trevor Paterson, Andy Law BMC Bioinformatics 2013, 14:246 (13 August 2013)

Abstract | Full text | PDF | PubMed

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