Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus
Journal of Neuroinflammation 2008, 5:16 (19 May 2008)
The metazoan history of the COE transcription factors. Selection of a variant HLH motif by mandatory inclusion of a duplicated exon in vertebrates
BMC Evolutionary Biology 2008, 8:131 (2 May 2008)
Gpnmb allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma R150 X
BMC Genetics 2008, 9:30 (10 April 2008)
Early virological suppression despite high frequency NNRTI resistance following perinatal prophylaxis in HIV-infected African infants
Retrovirology 2008, 5(Suppl 1):O27 (9 April 2008)
Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q
BMC Cancer 2008, 8:87 (1 April 2008)
Genome-wide linkage analysis reveals that the 3q21.1-q26.2 locus is consistently associated with the development of colorectal cancer in Swedish families with a strong family history of this malignancy.
Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation
BMC Developmental Biology 2008, 8:35 (1 April 2008)
Innate recognition of non-self nucleic acids
Genome Biology 2008, 9:211 (10 March 2008)
A variety of innate immune system receptors recognize and respond to the nucleic acids of invading pathogens.
Gene expression-based screening for inhibitors of PDGFR signaling
Genome Biology 2008, 9:R47 (1 March 2008)
Inhibitors of the platelet derived growth factor receptor (PDGFR) signaling pathway are isolated using gene expression-based high-throughput screening (GE-HTS), a method that is applicable to other pathways.
6 th International Symposium on Retroviral Nucleocapsid
Retrovirology 2008, 5:21 (25 February 2008)
The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse
BMC Neuroscience 2008, 9:26 (24 February 2008)
Hominoid chromosomal rearrangements on 17q map to complex regions of segmental duplication
Genome Biology 2008, 9:R28 (7 February 2008)
A FISH analysis of chromosome 17 homologs in primates suggests that genomic architecture has a direct role in karyotype evolution and in the genomic instability associated with human disease.
Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins
BMC Biochemistry 2008, 9:4 (30 January 2008)
Temporal order of bipolar cell genesis in the neural retina
Neural Development 2008, 3:2 (23 January 2008)
A genome-wide screen for noncoding elements important in primate evolution
BMC Evolutionary Biology 2008, 8:17 (23 January 2008)
Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling
BMC Biology 2008, 6:1 (14 January 2008)
Although the activation of Notch requires chaperone-mediated secretion and glycosylation, both performed by an O-fucosyltransferase (OFUT1), the chaperone activity of OFUT1 alone is sufficient to rescue neurogenesis in Ofut1 null mutant Drosophila embryos.
Low-level HIV-1 replication and the dynamics of the resting CD4 + T cell reservoir for HIV-1 in the setting of HAART
BMC Infectious Diseases 2008, 8:2 (2 January 2008)
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model
BMC Neuroscience 2007, 8:108 (19 December 2007)
Although nitric oxide synthase 2 (NOS2) is implicated in retinal ganglion cell degeneration in one experimental rat glaucoma model, pharmacologically or genetically decreased NOS2 activity does not impact on glaucomatous neurodegeneration in an inherited mouse model.
LGMD2I in a North American population
BMC Musculoskeletal Disorders 2007, 8:115 (24 November 2007)
The distributions, mechanisms, and structures of metabolite-binding riboswitches
Genome Biology 2007, 8:R239 (12 November 2007)
Phylogenetic analyses revealed insights into the distribution of riboswitch classes in different microbial groups, and structural analyses led to updated aptamer structure models and insights into the mechanism of these non-coding RNA structures.
Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans
van der Linden,
Neural Development 2007, 2:24 (6 November 2007)
Expression profiling in APP23 mouse brain: inhibition of A β amyloidosis and inflammation in response to LXR agonist treatment
Molecular Neurodegeneration 2007, 2:20 (22 October 2007)
A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila
Genome Biology 2007, 8:R203 (28 September 2007)
A second generation dsRNA library was used to re-assess factors that influence the outcome of transcriptional reporter-based whole-genome RNAi screens for the Wnt/Wingless (wg) and Hedgehog (hh)-signaling pathways.
Uncovering the mutation-fixation correlation in short lineages
BMC Evolutionary Biology 2007, 7:168 (21 September 2007)
Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer
Genome Biology 2007, 8:R191 (14 September 2007)
In an effort to deconvolute global gene-expression profiles, an interaction between some breast cancer cells and stromal fibroblasts was found to induce an interferon response, which may be associated with a greater propensity for tumor progression.
The promoter regions of the Myb-regulated Adora2B and Mcm4 genes co-localize with origins of DNA replication
BMC Molecular Biology 2007, 8:75 (6 September 2007)