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Work published with BioMed Central in the last 12 months by researchers at Howard Hughes Medical Institute HHMI
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Research article
Considering scores between unrelated proteins in the search database improves profile comparison Sadreyev RI, Wang Y, Grishin NV BMC Bioinformatics 2009, 10 :399 (4 December 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analysis of recent segmental duplications in the bovine genome Liu GE, Ventura M, Cellamare A, Chen L, Cheng Z, Zhu B, Li C, Song J, Eichler EE BMC Genomics 2009, 10 :571 (1 December 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Correction
Correction: Digital PCR provides sensitive and absolute calibration for high throughput sequencing White RA, Blainey PC, Fan HC, Quake SR BMC Genomics 2009, 10 :541 (19 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila Zhou B, Williams DW, Altman J, Riddiford LM, Truman JW Neural Development 2009, 4 :39 (2 November 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Editorial
Epigenetics & Chromatin celebrates its first anniversaryHenikoff S, Grosveld F Epigenetics & Chromatin 2009, 2 :13 (2 November 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Review
Synthetic lethality: a framework for the development of wiser cancer therapeutics Kaelin WG Genome Medicine 2009, 1 :99 (27 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Poster presentation
P09-11. Reduced replication capacity of NL4-3 chimeric viruses encoding RT-Integrase sequences from HIV-1 elite controllers Li C, Brumme ZL, Miura T, Rosato PC, Sela J, Brumme CJ, Heckerman D, Pereyra F, Walker BD, Brockman MA Retrovirology 2009, 6 (Suppl 3):P124 (22 October 2009) [Abstract ] [Full text ] [PDF ]
Research article
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye Wu Y, Zhuang Y, Han M, Xu T, Deng K BMC Developmental Biology 2009, 9 :53 (20 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Automated DNA mutation detection using universal conditions direct sequencing: application to ten muscular dystrophy genes Bennett RR, Schneider HE, Estrella E, Burgess S, Cheng AS, Barrett C, Lip V, Lai PS, Shen Y, Wu BL, Darras BT, Beggs AH, Kunkel LM BMC Genetics 2009, 10 :66 (18 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Invited speaker presentation
Retroviral restriction factors: new mechanisms of innate immunity Wolf D, Gao G, Guo X, Bick MJ, Carroll JWN, MacDonald MR, Goff SP Retrovirology 2009, 6 (Suppl 2):I1 (24 September 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Oral presentation
Targeting of MuLV Gag to the plasma membrane is mediated by PI(4,5)P2 and PhosphatidylSerine Hamard-Peron E, Juilliard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D Retrovirology 2009, 6 (Suppl 2):O15 (24 September 2009) [Abstract ] [Full text ] [PDF ]
Poster presentation
Identification of the 'basal' human LINE-1 retrotransposition complex Doucet AJ, Sahinovic E, Bucheton A, Moran JV, Gilbert N Retrovirology 2009, 6 (Suppl 2):P32 (24 September 2009) [Abstract ] [Full text ] [PDF ]
Poster presentation
The first crystal structure of cyclic GMP-dependent protein kinase I dimerization/docking domain reveals molecular details of isoform-specific anchoring Casteel DE, Smith-Nguyen EV, Sankaran B, Spraggon G, Hampton EN, Pilz RB, Taylor SS, Kim C BMC Pharmacology 2009, 9 (Suppl 1):P6 (11 August 2009) [Abstract ] [Full text ] [PDF ]
Methodology article
Efficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates Voehringer D, Wu D, Liang HE, Locksley RM BMC Biotechnology 2009, 9 :69 (28 July 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions MacArthur S, Li XY, Li J, Brown JB, Chu HC, Zeng L, Grondona BP, Hechmer A, Simirenko L, Keränen SVE, Knowles DW, Stapleton M, Bickel P, Biggin MD, Eisen MB Genome Biology 2009, 10 :R80 (23 July 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Semi-automated curation of protein subcellular localization: a text mining-based approach to Gene Ontology (GO) Cellular Component curation Van Auken K, Jaffery J, Chan J, Müller HM, Sternberg PW BMC Bioinformatics 2009, 10 :228 (21 July 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus ) inoculated with brain homogenates containing avian bornavirus 4 Gancz AY, Kistler AL, Greninger AL, Farnoushi Y, Mechani S, Perl S, Berkowitz A, Perez N, Clubb S, DeRisi JL, Ganem D, Lublin A Virology Journal 2009, 6 :100 (9 July 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior Whittaker AJ, Sternberg PW BMC Biology 2009, 7 :33 (22 June 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
The complete genome of klassevirus a novel picornavirus in pediatric stool Greninger AL, Runckel C, Chiu CY, Haggerty T, Parsonnet J, Ganem D, DeRisi JL Virology Journal 2009, 6 :82 (18 June 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of candidate structured RNAs in the marine organism 'Candidatus Pelagibacter ubique' Meyer MM, Ames TD, Smith DP, Weinberg Z, Schwalbach MS, Giovannoni SJ, Breaker RR BMC Genomics 2009, 10 :268 (16 June 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana Zhang X, Bernatavichute YV, Cokus S, Pellegrini M, Jacobsen SE Genome Biology 2009, 10 :R62 (9 June 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Tissue-specific variation in DNA methylation levels along human chromosome 1 De Bustos C, Ramos E, Young JM, Tran RK, Menzel U, Langford CF, Eichler EE, Hsu L, Henikoff S, Dumanski JP, Trask BJ Epigenetics & Chromatin 2009, 2 :7 (8 June 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice Stowell NC, Seideman J, Raymond HA, Smalley KA, Lamb RJ, Egenolf DD, Bugelski PJ, Murray LA, Marsters PA, Bunting RA, Flavell RA, Alexopoulou L, San Mateo LR, Griswold DE, Sarisky RT, Mbow ML, Das AM Respiratory Research 2009, 10 :43 (1 June 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays Bloom JS, Khan Z, Kruglyak L, Singh M, Caudy AA BMC Genomics 2009, 10 :221 (12 May 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research
PfeIK1, a eukaryotic initiation factor 2 kinase of the human malaria parasite Plasmodium falciparum , regulates stress-response to amino-acid starvation Fennell C, Babbitt S, Russo I, Wilkes J, Ranford-Cartwright L, Goldberg DE, Doerig C Malaria Journal 2009, 8 :99 (12 May 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Technical advance
Identification of microbial DNA in human cancer Duncan CG, Leary RJ, Lin JCH, Cummins J, Di C, Schaefer CF, Wang TL, Riggins GJ, Edwards J, Bigner D, Kopelovich L, Vogelstein B, Kinzler KW, Velculescu VE, Yan H BMC Medical Genomics 2009, 2 :22 (8 May 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Transcriptomic analysis of the entomopathogenic nematode Heterorhabditis bacteriophora TTO1 Bai X, Adams BJ, Ciche TA, Clifton S, Gaugler R, Hogenhout SA, Spieth J, Sternberg PW, Wilson RK, Grewal PS BMC Genomics 2009, 10 :205 (30 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Identifying promoter features of co-regulated genes with similar network motifs Harari O, del Val C, Romero-Zaliz R, Shin D, Huang H, Groisman EA, Zwir I BMC Bioinformatics 2009, 10 (Suppl 4):S1 (29 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Profile analysis and prediction of tissue-specific CpG island methylation classes Previti C, Harari O, Zwir I, del Val C BMC Bioinformatics 2009, 10 :116 (21 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Review
Sheldon-Hall syndrome Toydemir RM, Bamshad MJ Orphanet Journal of Rare Diseases 2009, 4 :11 (23 March 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Digital PCR provides sensitive and absolute calibration for high throughput sequencing White RA, Blainey PC, Fan HC, Quake SR BMC Genomics 2009, 10 :116 (19 March 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2) Winger JA, Hantschel O, Superti-Furga G, Kuriyan J BMC Structural Biology 2009, 9 :7 (24 February 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Sec61 , a subunit of the Sec61 protein translocation channel at the Endoplasmic Reticulum, is involved in the transport of Gurken to the plasma membrane. Kelkar A, Dobberstein B BMC Cell Biology 2009, 10 :11 (18 February 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A circuit supporting concentration-invariant odor perception in Drosophila Asahina K, Louis M, Piccinotti S, Vosshall LB Journal of Biology 2009, 8 :9 (26 January 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif Kinch LN, Grishin NV Biology Direct 2009, 4 :2 (21 January 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research
Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo Michel N, Goffinet C, Ganter K, Allespach I, KewalRamani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT Retrovirology 2009, 6 :2 (13 January 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Studying alternative splicing regulatory networks through partial correlation analysis Chen L, Zheng S Genome Biology 2009, 10 :R3 (9 January 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Heterogeneity in the developmental potential of motor neuron progenitors revealed by clonal analysis of single cells in vitro Agalliu D, Schieren I Neural Development 2009, 4 :2 (5 January 2009) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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