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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Swiss Tropical and Public Health Institute (Swiss TPH)

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1.

Research article   Open Access

Delivering at home or in a health facility? health-seeking behaviour of women and the role of traditional birth attendants in Tanzania

Constanze Pfeiffer, Rosemarie Mwaipopo BMC Pregnancy and Childbirth 2013, 13:55 (28 February 2013)

Abstract | Provisional PDF

2.

Research   Open Access

Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study

Olivier JT Briët, Melissa A Penny, Diggory Hardy, Taiwo S Awolola, Wim Van Bortel, Vincent Corbel, Roch K Dabiré, Josiane Etang, Benjamin G Koudou, Patrick K Tungu, Nakul Chitnis Malaria Journal 2013, 12:77 (25 February 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

The paper shows that standard and combination LLINs are likely to be cost effective against malaria even in areas with strong pyrethroid resistance. There is a strong message to funders and national malaria control programmes not abandon LLINs as the control tool of choice, because of fears that they might no longer be effective due to resistance.

3.

Research   Open Access

Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae

David Wimmersberger, Lucienne Tritten, Jennifer Keiser Parasites & Vectors 2013, 6:42 (22 February 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

We describe the development of a novel drug sensitivity assay for Trichuris muris first-stage larvae (L1). The established L1 motility assay provided accurate and reproducible drug effect data in vitro and will therefore serve as a useful tool in drug discovery for trichuriasis. Image: Trichuris muris first-stage larva.

4.

Research   Open Access

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains

Oyindamola O Abiodun, Reto Brun, Sergio Wittlin Malaria Journal 2013, 12:43 (31 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The study assessed the in vitro interaction of artemisin derivatives with thapsigargin using in vitro P. falciparum cultures. It demonstrated an additive effect of these compounds, suggesting that they do not interact at the same target site, as had previously been suggested.

5.

Research   Open Access

A new rapid diagnostic test for detection of anti-Schistosoma mansoni and anti-Schistosoma haematobium antibodies

Jean T Coulibaly, Eliézer K N’Goran, Jürg Utzinger, Michael J Doenhoff, Emily M Dawson Parasites & Vectors 2013, 6:29 (29 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In this study, we assessed the diagnostic performance of a new rapid diagnostic test that incorporates Schistosoma mansoni cercarial transformation fluid (SmCTF-RDT) for the detection of anti-S. mansoni and anti-S. haematobium antibodies by comparing it with microscopy for egg detection .Image: Two SmCTF-RDTs after adding a drop of whole blood and buffer in the cassette hole.

6.

Review   Open Access Highly Accessed

Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests

Sören L Becker, Jürg Vogt, Stefanie Knopp, Marcus Panning, David C Warhurst, Katja Polman, Hanspeter Marti, Lutz von Müller, Cedric P Yansouni, Jan Jacobs, Emmanuel Bottieau, Moussa Sacko, Suman Rijal, Fransiska Meyanti, Michael A Miles, Marleen Boelaert, Pascal Lutumba, Lisette van Lieshout, Eliézer K N’Goran, François Chappuis, Jürg Utzinger BMC Infectious Diseases 2013, 13:37 (24 January 2013)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Local perceptions of cholera and anticipated vaccine acceptance in Katanga province, democratic republic of Congo

Sonja Merten, Christian Schaetti, Cele Manianga, Bruno Lapika, Claire-Lise Chaignat, Raymond Hutubessy, Mitchell G Weiss BMC Public Health 2013, 13:60 (22 January 2013)

Abstract | Provisional PDF | PubMed

8.

Research   Open Access

Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study

Nicolas Marincek, Ann-Catherine Jörg, Philippe Brunner, Christian Schindler, Michael T Koller, Christoph Rochlitz, Jan Müller-Brand, Helmut R Maecke, Matthias Briel, Martin A Walter Journal of Translational Medicine 2013, 11:17 (15 January 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access Highly Accessed

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region

Salim Abdulla, Nahya Salim, Francisca Machera, Richard Kamata, Omar Juma, Mwanajaa Shomari, Sulende Kubhoja, Ali Mohammed, Grace Mwangoka, Thomas Aebi, Hassan Mshinda, David Schellenberg, Terrell Carter, Tonya Villafana, Marie-Claude Dubois, Amanda Leach, Marc Lievens, Johan Vekemans, Joe Cohen, W Ripley Ballou, Marcel Tanner Malaria Journal 2013, 12:11 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Data from a well designed and rigorously conducted phase II trial as part of RTS,S/AS vaccine clinical development to prevent malaria in sub-Saharan African children, with further results on safety immunogenicity and efficacy of the RTSS vaccine with the AS02 adjuvant.

10.

Research   Open Access

Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide

Benjamin Speich, Hanspeter Marti, Shaali M Ame, Said M Ali, Isaac I Bogoch, Jürg Utzinger, Marco Albonico, Jennifer Keiser Parasites & Vectors 2013, 6:3 (4 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In a randomised controlled trial using albendazole and nitazoxanide, 550 school-aged children on Pemba Island had formalin-fixed stool samples examined with an ether-concentration method before and 3 weeks after treatment. Three-quarters of the children were diagnosed with at least one intestinal protozoa species. Image: A child on Pemba Island during drug administration.

11.

Research   Open Access Highly Accessed

Modelling the cost-effectiveness of mass screening and treatment for reducing Plasmodium falciparum malaria burden

Valerie Crowell, Olivier JT Briët, Diggory Hardy, Nakul Chitnis, Nicolas Maire, Aurelio Pasquale, Thomas A Smith Malaria Journal 2013, 12:4 (3 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper presents a cost-effectiveness modelling study on the introduction of mass screening and treatment in a sub-Saharan African setting, in various transmission contexts and with varying ITN and case management coverage. This is an important potential policy question, with a thoughtful discussion of the limitations.

12.

Editorial   Open Access

Elimination of tropical disease through surveillance and response

Xiao-Nong Zhou, Robert Bergquist, Marcel Tanner Infectious Diseases of Poverty 2013, 2:1 (3 January 2013)

Abstract | Full text | PDF |  Editor’s summary

It is recommended that the surveillance-response systems to take place in two different stages corralling the basic components of the surveillance-response system for NTD elimination in developing countries, based on the innovative and effective One world-One health perspective to detect, report, analyze, interpret and take action. Image: taking surveillance of zoonotic diseases.

13.

Research   Open Access

Concordances and discrepancies between ICD-10 and DSM-IV criteria for anxiety disorders in childhood and adolescence

Carmen Adornetto, Andrea Suppiger, Tina In-Albon, Murielle Neuschwander, Silvia Schneider Child and Adolescent Psychiatry and Mental Health 2012, 6:40 (26 December 2012)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access Highly Accessed

Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change

Guo-Jing Yang, Marcel Tanner, Jürg Utzinger, John B Malone, Robert Bergquist, Emily YY Chan, Qi Gao, Xiao-Nong Zhou Malaria Journal 2012, 11:426 (21 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The authors present a prediction map of P. vivax malaria transmission in China and discuss its implications for future malaria control and elimination within the country, particularly within the context of past and future climate scenarios.

15.

Research   Open Access

Dynamics of Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children

Katarina Stete, Stefanie J Krauth, Jean T Coulibaly, Stefanie Knopp, Jan Hattendorf, Ivan Müller, Laurent K Lohourignon, Winfried V Kern, Eliézer K N’Goran, Jürg Utzinger Parasites & Vectors 2012, 5:298 (21 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study, conducted in south Cote d' Ivoire, assessed the dynamics of Schistosoma haematobium egg output and other infection parameters after praziquantel treatment in order to determine the optimal time point for measuring treatment efficacy in urogenital schistosomiasis. Image: Urine sample from a schoolchild in south Cote d' Ivoire, subjected to the filtration method.

16.

Research article   Open Access

Willingness to use a rapid diagnostic test for malaria in a rural area of central Côte d’Ivoire

Colombe Coffie Comoé, Allassane F Ouattara, Giovanna Raso, Marcel Tanner, Jürg Utzinger, Benjamin G Koudou BMC Public Health 2012, 12:1089 (18 December 2012)

Abstract | Full text | PDF | PubMed

17.

Research article   Open Access

Sex-specific effects of a parasite evolving in a female-biased host population

David Duneau, Pepijn Luijckx, Ludwig F Ruder, Dieter Ebert BMC Biology 2012, 10:104 (18 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A bacterial parasite of Daphnia magna castrates its hosts, apparently as an adaptation to the sex-bias in Daphnia populations towards females. Castration causes the female to grow larger, making it a better host for this parasite.

18.

Research   Open Access

Effect of combinations of marketed human anthelmintic drugs against Trichuris muris in vitro and in vivo

Jennifer Keiser, Lucienne Tritten, Roberto Adelfio, Mireille Vargas Parasites & Vectors 2012, 5:292 (11 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Drug combination effects of albendazole, mebendazole, levamisole, pyrantel pamoate and ivermectin were studied against Trichuris muris. Four synergistic and one additive combination were identified in vivo. Albendazole-mebendazole should be investigated further in preclinical studies. Image: SEM of anterior region of Trichuris muris.

19.

Research article   Open Access Highly Accessed

Molecular phylogeny of microhylid frogs (Anura: Microhylidae) with emphasis on relationships among New World genera

Rafael O de Sá, Jeffrey W Streicher, Relebohile Sekonyela, Mauricio C Forlani, Simon P Loader, Eli Greenbaum, Stephen Richards, Célio F B Haddad BMC Evolutionary Biology 2012, 12:241 (10 December 2012)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

Plasma lipoprotein-associated phospholipase A2 activity in Alzheimer's disease, amnestic mild cognitive impairment, and cognitively healthy elderly subjects: a cross-sectional study

Julie E Davidson, Andrew Lockhart, Leslie Amos, Heide A Stirnadel-Farrant, Vincent Mooser, Marc Sollberger, Axel Regeniter, Andreas U Monsch, Michael C Irizarry Alzheimer's Research & Therapy 2012, 4:51 (7 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Levels of plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) did not correlate with cerebrospinal fluid biomarkers such as Abeta and Tau in Alzheimer's disease patients in a cross-sectional study.

21.

Research article   Open Access

Domestic dog demographic structure and dynamics relevant to rabies control planning in urban areas in Africa: the case of Iringa, Tanzania

Alena S Gsell, Darryn L Knobel, Rudovick R Kazwala, Penelope Vounatsou, Jakob Zinsstag BMC Veterinary Research 2012, 8:236 (5 December 2012)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access Highly Accessed

Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for detection of Leishmania DNA in buffy coat from visceral leishmaniasis patients

Md Gulam Musawwir Khan, Khondaker Rifat Hasan Bhaskar, Md Abdus Salam, Tania Akther, Gerd Pluschke, Dinesh Mondal Parasites & Vectors 2012, 5:280 (3 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Spleen tissue aspiration is an invasive and highly risky procedure which may cause life threatening internal bleeding in 1 of 1000 procedures, sometime with fatal outcomes. Thus there is a need for an accurate but risk-free diagnostic tool for VL. Image: Spleen tissue aspiration for diagnosis of VL.

23.

Research highlight   Subscription Highly Accessed

Dicer partners expand the repertoire of miRNA targets

Lukasz Jaskiewicz, Mihaela Zavolan Genome Biology 2012, 13:179 (29 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A Research Highlight by Lukasz Jaskiewicz and Mihaela Zavolan discusses how cofactors modify Dicer processing and, consequently, transcriptional networks

24.

Research   Open Access

Differences in weight status and energy-balance related behaviors among schoolchildren in German-speaking Switzerland compared to seven countries in Europe

Michael Herzig, Alain Dössegger, Urs Mäder, Susi Kriemler, Tina Wunderlin, Leticia Grize, Johannes Brug, Yannis Manios, Charlotte Braun-Fahrländer, Bettina Bringolf-Isler International Journal of Behavioral Nutrition and Physical Activity 2012, 9:139 (29 November 2012)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

Boonrat Chantong, Denise V Kratschmar, Lyubomir G Nashev, Zoltan Balazs, Alex Odermatt Journal of Neuroinflammation 2012, 9:260 (28 November 2012)

Abstract | Full text | PDF | PubMed

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