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351.

Research article   Open Access Highly Accessed

The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells

Heather C Workman, Jamie K Miller, Ellen Q Ingalla, Rouminder P Kaur, Diane I Yamamoto, Laurel A Beckett, Lawrence JT Young, Robert D Cardiff, Alexander D Borowsky, Kermit L Carraway, Colleen Sweeney, Kermit L Carraway Breast Cancer Research 2009, 11:R70 (18 September 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The membrane mucin, MUC4, is re-expressed during breast cancer progression and enhances malignancy by promoting the survival and proliferation of non-adherent actively metastizing cells.

352.

Research article   Open Access Highly Accessed

Physician career satisfaction within specialties

J Paul Leigh, Daniel J Tancredi, Richard L Kravitz BMC Health Services Research 2009, 9:166 (16 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

353.

Study protocol   Open Access Highly Accessed

Cancer Health Empowerment for Living without Pain (Ca-HELP): study design and rationale for a tailored education and coaching intervention to enhance care of cancer-related pain

Richard L Kravitz, Daniel J Tancredi, Richard L Street, Donna Kalauokalani, Tim Grennan, Ted Wun, Christina Slee, Dionne Evans Dean, Linda Lewis, Naomi Saito, Peter Franks BMC Cancer 2009, 9:319 (9 September 2009)

Abstract | Full text | PDF | PubMed

354.

Research Article   Open Access

Opportunistic Spectrum Access in Self-Similar Primary Traffic

Xiangyang Xiao, Keqin Liu, Qing Zhao EURASIP Journal on Advances in Signal Processing 2009, 2009:762547 (7 September 2009)

Abstract | Full text | PDF

355.

Research article   Open Access

Comparing genomic expression patterns across plant species reveals highly diverged transcriptional dynamics in response to salt stress

Harkamal Walia, Clyde Wilson, Abdelbagi M Ismail, Timothy J Close, Xinping Cui BMC Genomics 2009, 10:398 (25 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

356.

Research article   Open Access Highly Accessed

A physical map of the papaya genome with integrated genetic map and genome sequence

Qingyi Yu, Eric Tong, Rachel L Skelton, John E Bowers, Meghan R Jones, Jan E Murray, Shaobin Hou, Peizhu Guan, Ricelle A Acob, Ming-Cheng Luo, Paul H Moore, Maqsudul Alam, Andrew H Paterson, Ray Ming BMC Genomics 2009, 10:371 (7 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

357.

Research article   Open Access

Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women

Carolyn J Crandall, Mary E Sehl, Sybil L Crawford, Ellen B Gold, Laurel A Habel, Lesley M Butler, MaryFran R Sowers, Gail A Greendale, Janet S Sinsheimer Breast Cancer Research 2009, 11:R51 (27 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

358.

Research article   Open Access Highly Accessed

Rapid fixation of non-native alleles revealed by genome-wide SNP analysis of hybrid tiger salamanders

Benjamin M Fitzpatrick, Jarrett R Johnson, D Kevin Kump, H Bradley Shaffer, Jeramiah J Smith, S Randal Voss BMC Evolutionary Biology 2009, 9:176 (24 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In hybrid zones, introgression of a few strongly selected alleles from Barred Tiger Salamanders into the endangered Californian Tiger Salamander population might make preservation of genetically distinct populations of the endangered species difficult.

359.

Research article   Open Access Highly Accessed

An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels

Rami Nassir, Roman Kosoy, Chao Tian, Phoebe A White, Lesley M Butler, Gabriel Silva, Rick Kittles, Marta E Alarcon-Riquelme, Peter K Gregersen, John W Belmont, Francisco M De La Vega, Michael F Seldin BMC Genetics 2009, 10:39 (24 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

360.

Research article   Open Access

Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR)

Patrick S Wong, Wen Li, Christoph F Vogel, Fumio Matsumura BMC Cancer 2009, 9:234 (15 July 2009)

Abstract | Full text | PDF | PubMed

361.

Research article   Open Access Highly Accessed

Genetic specificity and potential for local adaptation between dengue viruses and mosquito vectors

Louis Lambrechts, Christine Chevillon, Rebecca G Albright, Butsaya Thaisomboonsuk, Jason H Richardson, Richard G Jarman, Thomas W Scott BMC Evolutionary Biology 2009, 9:160 (9 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

362.

Review   Open Access Highly Accessed

Retinal waves are unlikely to instruct the formation of eye-specific retinogeniculate projections

Leo M Chalupa Neural Development 2009, 4:25 (6 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Please see the related review article from Marla Feller, Neural Development 2009, 4:24

363.

Research   Open Access Highly Accessed

Dealing with heterogeneity of treatment effects: is the literature up to the challenge?

Nicole B Gabler, Naihua Duan, Diana Liao, Joann G Elmore, Theodore G Ganiats, Richard L Kravitz Trials 2009, 10:43 (19 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Heterogeneity of treatment effects was neither rigorously nor routinely reported in a sample of randomised controlled trials published in 5 leading medical journals, suggesting the need for revised standards of reporting.

364.

Research article   Open Access Highly Accessed

Deaths among tuberculosis cases in Shanghai, China: who is at risk?

Xin Shen, Kathryn DeRiemer, Zheng'an Yuan, Mei Shen, Zhen Xia, Xiaohong Gui, Lili Wang, Jian Mei BMC Infectious Diseases 2009, 9:95 (17 June 2009)

Abstract | Full text | PDF | PubMed

365.

Research   Open Access Highly Accessed

Tissue-specific variation in DNA methylation levels along human chromosome 1

Cecilia De Bustos, Edward Ramos, Janet M Young, Robert K Tran, Uwe Menzel, Cordelia F Langford, Evan E Eichler, Li Hsu, Steve Henikoff, Jan P Dumanski, Barbara J Trask Epigenetics & Chromatin 2009, 2:7 (8 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

366.

Short report   Open Access

In vivo multiplex quantitative analysis of 3 forms of alpha melanocyte stimulating hormone in pituitary of prolyl endopeptidase deficient mice

Bertrand Perroud, Rudy J Alvarado, Glenda M Espinal, Alex R Morado, Brett S Phinney, Craig H Warden Molecular Brain 2009, 2:14 (2 June 2009)

Abstract | Full text | PDF | PubMed

367.

Research article   Open Access

Detection and validation of single feature polymorphisms using RNA expression data from a rice genome array

Sung-Hyun Kim, Prasanna R Bhat, Xinping Cui, Harkamal Walia, Jin Xu, Steve Wanamaker, Abdelbagi M Ismail, Clyde Wilson, Timothy J Close BMC Plant Biology 2009, 9:65 (29 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

368.

Research   Open Access

Properties of virion transactivator proteins encoded by primate cytomegaloviruses

Iain P Nicholson, Jane S Sutherland, Tanya N Chaudry, Earl L Blewett, Peter A Barry, Mary Nicholl, Chris M Preston Virology Journal 2009, 6:65 (27 May 2009)

Abstract | Full text | PDF | PubMed

369.

Research   Open Access Highly Accessed

House design modifications reduce indoor resting malaria vector densities in rice irrigation scheme area in western Kenya

Harrysone Atieli, Diana Menya, Andrew Githeko, Thomas Scott Malaria Journal 2009, 8:108 (19 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

House modifications involving insect screen ceilings made from locally available materials and smaller nettings incorporated in house construction have the potential to reduce human exposure to malaria vectors, and thus parasite infection, in a rice irrigation scheme of western Kenya

370.

Review   Free Highly Accessed

Developments in the scientific understanding of osteoporosis

Nancy E Lane, Wei Yao Arthritis Research & Therapy 2009, 11:228 (19 May 2009)

Abstract | Full text | PDF | PubMed

371.

Research article   Open Access Highly Accessed

Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis

Stephanie L Barrow, John RL Constable, Eliana Clark, Faten El-Sabeawy, A Kimberley McAllister, Philip Washbourne Neural Development 2009, 4:17 (18 May 2009)

Abstract | Full text | PDF | PubMed

372.

Minireview   Free

Parental squabbles and genome expression: lessons from the polyploids

Daniela Pignatta, Luca Comai Journal of Biology 2009, 8:43 (1 May 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Many plant species have evolved from hybrids that have retained the diploid genomes of both parents; Pignatta and Comai discuss a study in BMC Biology on cotton allopolyploids illustrating the novel patterns of expression that can result.

373.

Research article   Open Access Highly Accessed

Resource heterogeneity and foraging behaviour of cattle across spatial scales

Santiago A Utsumi, Carlos A Cangiano, Julio R Galli, Mary B McEachern, Montague W Demment, Emilio A Laca BMC Ecology 2009, 9:9 (24 April 2009)

Abstract | Full text | PDF | PubMed

374.

Commentary   Open Access Highly Accessed

Unlocking the bovine genome

Ross L Tellam, Danielle G Lemay, Curtis P Van Tassell, Harris A Lewin, Kim C Worley, Christine G Elsik BMC Genomics 2009, 10:193 (24 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An extensive collaboration involving over 300 scientists from 25 different countries has analyzed the draft genome sequence of cattle, yielding insights into ruminant evolution and domestication and providing an invaluable research resource for the beef and dairy industries.

375.

Research article   Open Access Highly Accessed

Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution

Claus Kemkemer, Matthias Kohn, David N Cooper, Lutz Froenicke, Josef Högel, Horst Hameister, Hildegard Kehrer-Sawatzki BMC Evolutionary Biology 2009, 9:84 (24 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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