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1.

Research   Open Access

Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells

Chung-Il An, Edward Ganio, Nobuko Hagiwara Skeletal Muscle 2013, 3:11 (10 May 2013)

Abstract | Provisional PDF | PubMed

2.

Research   Open Access

Testosterone-derived estradiol production by male endothelium is robust and dependent on p450 aromatase via estrogen receptor alpha

Amparo C Villablanca, Sarada Tetali, Robin Altman, Kenneth F Ng, John C Rutledge SpringerPlus 2013, 2:214 (9 May 2013)

Abstract | Provisional PDF

3.

Research   Open Access

Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults

Andrew J Clifford, Gonzalo Rincon, Janel E Owens, Juan F Medrano, Alanna J Moshfegh, David J Baer, Janet A Novotny Lipids in Health and Disease 2013, 12:66 (8 May 2013)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access Highly Accessed

Influence of arthritis-related protein (BBF01) on infectivity of Borrelia burgdorferi B31

Denise Imai, Kevin Holden, Eric M Velazquez, Sunlian Feng, Emir Hodzic, Stephen W Barthold BMC Microbiology 2013, 13:100 (7 May 2013)

Abstract | Provisional PDF | PubMed

5.

Research   Open Access

Sex differences matter in the gut: effect on mucosal immune activation and inflammation

Sumathi Sankaran-Walters, Monica Macal, Irina Grishina, Lauren Nagy, Larissa Goulart, Kathryn Coolidge, Jay Li, Anne Fenton, Theodore Williams, Mary K Miller, Jason Flamm, Thomas Prindiville, Michael George, Satya Dandekar Biology of Sex Differences 2013, 4:10 (7 May 2013)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access

Tracking animals in freshwater with electronic tags: past, present and future

Steven J Cooke, Jonathan D Midwood, Jason D Thiem, Peter Klimley, Martyn C Lucas, Eva B Thorstad, John Eiler, Chris Holbrook, Brendan C Ebner Animal Biotelemetry 2013, 1:5 (1 May 2013)

Abstract | Full text | PDF

7.

Review   Open Access

Evo-devo of human adolescence: beyond disease models of early puberty

Ze'ev Hochberg, Jay Belsky BMC Medicine 2013, 11:113 (29 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ze’ev Hochberg and Jay Belsky review the development of human adolescents from an endocrinological and social perspective, arguing that understanding the environmental impact on development will help inform further research.

8.

Research article   Open Access Highly Accessed

Genome analyses of the wheat yellow (stripe) rust pathogen Puccinia striiformis f. sp. tritici reveal polymorphic and haustorial expressed secreted proteins as candidate effectors

Dario Cantu, Vanesa Segovia, Daniel MacLean, Rosemary Bayles, Xianming Chen, Sophien Kamoun, Jorge Dubcovsky, Diane GO Saunders, Cristobal Uauy BMC Genomics 2013, 14:270 (22 April 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Notch4 is required for tumor onset and perfusion

Maria José Costa, Xiaoqing Wu, Henar Cuervo, Ruchika Srinivasan, Seth K Bechis, Ellen Cheang, Olivera Marjanovic, Thomas Gridley, Christin A Cvetic, Rong A Wang Vascular Cell 2013, 5:7 (20 April 2013)

Abstract | Full text | PDF | PubMed

10.

Study protocol   Open Access

Targeted versus tailored multimedia patient engagement to enhance depression recognition and treatment in primary care: randomized controlled trial protocol for the AMEP2 study

Daniel J Tancredi, Christina K Slee, Anthony Jerant, Peter Franks, Jasmine Nettiksimmons, Camille Cipri, Dustin Gottfeld, Julia Huerta, Mitchell D Feldman, Maja Jackson-Triche, Steven Kelly-Reif, Andrew Hudnut, Sarah Olson, Janie Shelton, Richard L Kravitz BMC Health Services Research 2013, 13:141 (17 April 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access Highly Accessed

No improvement in socioeconomic inequalities in birthweight and preterm birth over four decades: a population-based cohort study

Svetlana V Glinianaia, Rakesh Ghosh, Judith Rankin, Mark S Pearce, Louise Parker, Tanja Pless-Mulloli BMC Public Health 2013, 13:345 (15 April 2013)

Abstract | Full text | PDF | PubMed

12.

Research article   Open Access

Reevaluation of the evolutionary events within recA/RAD51 phylogeny

Sree V Chintapalli, Gaurav Bhardwaj, Jagadish Babu, Loukia Hadjiyianni, Yoojin Hong, George K Todd, Casey A Boosalis, Zhenhai Zhang, Xiaofan Zhou, Hong Ma, Andriy Anishkin, Damian B van Rossum, Randen L Patterson BMC Genomics 2013, 14:240 (10 April 2013)

Abstract | Full text | PDF | PubMed

13.

Study protocol   Open Access Highly Accessed

Values and options in cancer care (VOICE): study design and rationale for a patient-centered communication and decision-making intervention for physicians, patients with advanced cancer, and their caregivers

Michael Hoerger, Ronald M Epstein, Paul C Winters, Kevin Fiscella, Paul R Duberstein, Robert Gramling, Phyllis N Butow, Supriya G Mohile, Paul R Kaesberg, Wan Tang, Sandy Plumb, Adam Walczak, Anthony L Back, Daniel Tancredi, Alison Venuti, Camille Cipri, Gisela Escalera, Carol Ferro, Don Gaudion, Beth Hoh, Blair Leatherwood, Linda Lewis, Mark Robinson, Peter Sullivan, Richard L Kravitz BMC Cancer 2013, 13:188 (9 April 2013)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access Highly Accessed

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

Kelly M Bush, Benjamin TK Yuen, Bonnie L Barrilleaux, John W Riggs, Henriette O’Geen, Rebecca F Cotterman, Paul S Knoepfler Epigenetics & Chromatin 2013, 6:7 (9 April 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access Highly Accessed

Comparison of antioxidant activity and flavanol content of cacao beans processed by modern and traditional Mesoamerican methods

Elizabeth Chin, Kenneth B Miller, Mark J Payne, W Jeffery Hurst, David A Stuart Heritage Science 2013, 1:9 (5 April 2013)

Abstract | Full text | PDF

16.

Methods   Open Access

Generation of a luciferase-based reporter for CHH and CG DNA methylation in Arabidopsis thaliana

Thanh Theresa Dinh, Michael O’Leary, So Youn Won, Shengben Li, Lorena Arroyo, Xigang Liu, Andrew Defries, Binglian Zheng, Sean R Cutler, Xuemei Chen Silence 2013, 4:1 (5 April 2013)

Abstract | Full text | PDF | PubMed

17.

Editorial   Open Access

Why publish Animal Biotelemetry?

A Peter Klimley Animal Biotelemetry 2013, 1:1 (4 April 2013)

Abstract | Full text | PDF |  Editor’s summary

In this introductory editorial from the Editor-in-Chief, Pete Klimley, the aims and purpose of Animal Biotelemetry are discussed in the context along with a brief account of telemetry research and recent advances in this field.

18.

Database   Open Access Highly Accessed

RegTransBase – a database of regulatory sequences and interactions based on literature: a resource for investigating transcriptional regulation in prokaryotes

Michael J Cipriano, Pavel N Novichkov, Alexey E Kazakov, Dmitry A Rodionov, Adam P Arkin, Mikhail S Gelfand, Inna Dubchak BMC Genomics 2013, 14:213 (2 April 2013)

Abstract | Full text | PDF | PubMed

19.

Nano Express   Open Access Highly Accessed

High-reproducibility, flexible conductive patterns fabricated with silver nanowire by drop or fit-to-flow method

Yu Tao, Yuxiao Tao, Liuyang Wang, Biaobing Wang, Zhenguo Yang, Yanlong Tai Nanoscale Research Letters 2013, 8:147 (29 March 2013)

Abstract | Full text | PDF | PubMed

20.

Debate   Open Access Highly Accessed

Enhancing the scoping study methodology: a large, inter-professional team’s experience with Arksey and O’Malley’s framework

Helena ML Daudt, Catherine van Mossel, Samantha J Scott BMC Medical Research Methodology 2013, 13:48 (23 March 2013)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access

Attentional bias for trauma-related words: exaggerated emotional Stroop effect in Afghanistan and Iraq war veterans with PTSD

Victoria Ashley, Nikki Honzel, Jary Larsen, Timothy Justus, Diane Swick BMC Psychiatry 2013, 13:86 (14 March 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model

Gregory T Wurz, Audrey M Gutierrez, Brittany E Greenberg, Daniel P Vang, Stephen M Griffey, Chiao-Jung Kao, Michael Wolf, Michael W DeGregorio Journal of Translational Medicine 2013, 11:64 (13 March 2013)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Comparative analysis of protein-protein interactions in the defense response of rice and wheat

Dario Cantu, Baoju Yang, Randy Ruan, Kun Li, Virginia Menzo, Daolin Fu, Mawsheng Chern, Pamela C Ronald, Jorge Dubcovsky BMC Genomics 2013, 14:166 (12 March 2013)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access

Abundance, behavior and entomological inoculation rates of anthropophilic anophelines from a primary Colombian malaria endemic area

Nelson Naranjo-Diaz, Doris A Rosero, Guillermo Rua-Uribe, Shirley Luckhart, Margarita M Correa Parasites & Vectors 2013, 6:61 (7 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Entomological and transmission parameters were evaluated to incriminate potential anopheline vectors in three localities of a major Colombian malaria endemic region. The results indicated that Anopheles nuneztovari and Anopheles darlingi continue to be the most important malaria vectors in this region. This is the first report of Anopheles triannulatus, natural infection in Colombia. Image: Collection site, El Loro locality, in the UCS malaria endemic region.

25.

Research   Open Access

Deletions in the pyruvate pathway of Salmonella Typhimurium alter SPI1-mediated gene expression and infectivity

Jason Abernathy, Carolina Corkill, Carolee Hinojosa, Xianyao Li, Huaijun Zhou Journal of Animal Science and Biotechnology 2013, 4:5 (25 February 2013)

Abstract | Full text | PDF | PubMed

26.

Research   Open Access

Some inequalities for the minimum eigenvalue of the Hadamard product of an M-matrix and its inverse

Guanghui Cheng, Qin Tan, Zhuande Wang Journal of Inequalities and Applications 2013, 2013:65 (21 February 2013)

Abstract | Full text | PDF

27.

Research article   Open Access Highly Accessed

Evolution of a horizontally acquired legume gene, albumin 1, in the parasitic plant Phelipanche aegyptiaca and related species

Yeting Zhang, Monica Fernandez-Aparicio, Eric K Wafula, Malay Das, Yuannian Jiao, Norman J Wickett, Loren A Honaas, Paula E Ralph, Martin F Wojciechowski, Michael P Timko, John I Yoder, James H Westwood, Claude W dePamphilis BMC Evolutionary Biology 2013, 13:48 (20 February 2013)

Abstract | Full text | PDF | PubMed

28.

Research article   Open Access Highly Accessed

Allometry indicates giant eyes of giant squid are not exceptional

Lars Schmitz, Ryosuke Motani, Christopher E Oufiero, Christopher H Martin, Matthew D McGee, Ashlee R Gamarra, Johanna J Lee, Peter C Wainwright BMC Evolutionary Biology 2013, 13:45 (18 February 2013)

Abstract | Full text | PDF | PubMed

29.

Research article   Open Access

The differentially regulated genes TvQR1 and TvPirin of the parasitic plant Triphysaria exhibit distinctive natural allelic diversity

Quy A Ngo, Huguette Albrecht, Takashi Tsuchimatsu, Ueli Grossniklaus BMC Plant Biology 2013, 13:28 (18 February 2013)

Abstract | Full text | PDF | PubMed

30.

Research   Open Access

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease

Ted Wun, Denis Soulieres, Andrew L Frelinger, Lakshmanan Krishnamurti, Enrico M Novelli, Abdullah Kutlar, Kenneth I Ataga, Charles L Knupp, Lillian E McMahon, John J Strouse, Chunmei Zhou, Lori E Heath, Chuke E Nwachuku, Joseph A Jakubowski, Jeffrey S Riesmeyer, Kenneth J Winters Journal of Hematology & Oncology 2013, 6:17 (17 February 2013)

Abstract | Full text | PDF | PubMed

31.

Short report   Open Access Highly Accessed

A novel bocavirus in canine liver

Linlin Li, Patricia A Pesavento, Christian M Leutenegger, Marko Estrada, Lark L Coffey, Samia N Naccache, Erik Samayoa, Charles Chiu, Jianming Qiu, Chunlin Wang, Xutao Deng, Eric Delwart Virology Journal 2013, 10:54 (13 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A new species of bocavirus has been identified in the liver of a dog with haemorrhagic gastoenteritis and is highly genetically distinct from the two known canine bocaviruses.

32.

Research   Open Access

The regulatory function of social referencing in preschoolers with Down syndrome or Williams syndrome

Angela John Thurman, Carolyn B Mervis Journal of Neurodevelopmental Disorders 2013, 5:2 (13 February 2013)

Abstract | Full text | PDF | PubMed

33.

Research article   Open Access Highly Accessed

Insights into the evolution of Darwin’s finches from comparative analysis of the Geospiza magnirostris genome sequence

Chris M Rands, Aaron Darling, Matthew Fujita, Lesheng Kong, Matthew T Webster, Céline Clabaut, Richard D Emes, Andreas Heger, Stephen Meader, Michael Brent Hawkins, Michael B Eisen, Clotilde Teiling, Jason Affourtit, Benjamin Boese, Peter R Grant, Barbara Rosemary Grant, Jonathan A Eisen, Arhat Abzhanov, Chris P Ponting BMC Genomics 2013, 14:95 (12 February 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

204 years after Charles Darwin’s birth, sequencing of the genome of the Darwin’s Finch Geospiza magnirostris reveals over 13,000 predicted genes, of which two under positive selection may have contributed to beak morphology evolution, which so interested Darwin.

34.

Research   Open Access

Using infrared eye-tracking to explore ordinal numerical processing in toddlers with Fragile X Syndrome

Emily R Owen, Heidi A Baumgartner, Susan M Rivera Journal of Neurodevelopmental Disorders 2013, 5:1 (12 February 2013)

Abstract | Full text | PDF | PubMed

35.

Methodology   Open Access

Predicting non-isometric fatigue induced by electrical stimulation pulse trains as a function of pulse duration

M Susan Marion, Anthony S Wexler, Maury L Hull Journal of NeuroEngineering and Rehabilitation 2013, 10:13 (2 February 2013)

Abstract | Full text | PDF | PubMed

36.

Systematic review   Open Access

Assessing community-based conservation projects: A systematic review and multilevel analysis of attitudinal, behavioral, ecological, and economic outcomes

Jeremy Brooks, Kerry Waylen, Monique Mulder Environmental Evidence 2013, 2:2 (31 January 2013)

Abstract | Full text | PDF

37.

Comment   Free Highly Accessed

The passionate life of Simon Chan

Luca Comai Genome Biology 2013, 14:103 (30 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Luca Comai remembers the late Simon Chan, whose work on centromere evolution features in the current issue of Genome Biology

38.

Research   Open Access Highly Accessed

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution

Daniël P Melters, Keith R Bradnam, Hugh A Young, Natalie Telis, Michael R May, J Ruby, Robert Sebra, Paul Peluso, John Eid, David Rank, José Garcia, Joseph L DeRisi, Timothy Smith, Christian Tobias, Jeffrey Ross-Ibarra, Ian Korf, Simon WL Chan Genome Biology 2013, 14:R10 (30 January 2013)

Abstract | Provisional PDF | PubMed | F1000 Biology |  Editor’s summary

An analysis of centromere tandem repeats in 282 species reveals similar modes of evolution despite the lack of sequence conservation

39.

Research   Open Access

MeCP2 modulates gene expression pathways in astrocytes

Dag H Yasui, Huichun Xu, Keith W Dunaway, Janine M LaSalle, Lee-Way Jin, Izumi Maezawa Molecular Autism 2013, 4:3 (25 January 2013)

Abstract | Full text | PDF | PubMed

40.

Short report   Open Access

Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism

Eleonora Napoli, Sarah Wong, Cecilia Giulivi Molecular Autism 2013, 4:2 (25 January 2013)

Abstract | Full text | PDF | PubMed

41.

Research article   Open Access

A cross-sectional study of the prevalence and risk factors for hypertension in rural Nepali women

Rumana J Khan, Christine P Stewart, Parul Christian, Kerry J Schulze, Lee Wu, Steven C LeClerq, Subarna K Khatry, Keith P West BMC Public Health 2013, 13:55 (21 January 2013)

Abstract | Full text | PDF | PubMed

42.

Research article   Open Access Highly Accessed

Comparative analysis of complete mitochondrial genome sequences confirms independent origins of plant-parasitic nematodes

Tahera Sultana, Jiyeon Kim, Sang-Hwa Lee, Hyerim Han, Sanghee Kim, Gi-Sik Min, Steven A Nadler, Joong-Ki Park BMC Evolutionary Biology 2013, 13:12 (18 January 2013)

Abstract | Full text | PDF | PubMed

43.

Software   Open Access

JContextExplorer: a tree-based approach to facilitate cross-species genomic context comparison

Phillip Seitzer, Tu Anh Huynh, Marc T Facciotti BMC Bioinformatics 2013, 14:18 (16 January 2013)

Abstract | Full text | PDF | PubMed

44.

Letter to the Editor   Open Access

Response to Dr. Roger’s letter: further studies are necessary in order to conclude a causal association between the consumption of monosodium L-glutamate (MSG) and the prevalence of metabolic syndrome in the rural Thai population

Tonkla Insawang, Carlo Selmi, Ubon Cha’on, M Eric Gershwin, Puangrat Yongvanit, Vitoon Prasongwattana Nutrition & Metabolism 2013, 10:10 (15 January 2013)

Abstract | Full text | PDF | PubMed

45.

Software   Open Access Highly Accessed

MetAMOS: a modular and open source metagenomic assembly and analysis pipeline

Todd J Treangen, Sergey Koren, Daniel D Sommer, Bo Liu, Irina Astrovskaya, Brian Ondov, Aaron E Darling, Adam M Phillippy, Mihai Pop Genome Biology 2013, 14:R2 (15 January 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A modular, metagenomic analysis and assembly pipeline that inputs next-generation sequencing reads to generate genomic scaffolds and open reading frames

46.

Research   Open Access

Novel lanthanide-labeled metal oxide nanoparticles improve the measurement of in vivo clearance and translocation

Aamir D Abid, Donald S Anderson, Gautom K Das, Laura S Van Winkle, Ian M Kennedy Particle and Fibre Toxicology 2013, 10:1 (10 January 2013)

Abstract | Full text | PDF | PubMed

47.

Research article   Open Access

Functional genomics of a generalist parasitic plant: Laser microdissection of host-parasite interface reveals host-specific patterns of parasite gene expression

Loren A Honaas, Eric K Wafula, Zhenzhen Yang, Joshua P Der, Norman J Wickett, Naomi S Altman, Christopher G Taylor, John I Yoder, Michael P Timko, James H Westwood, Claude W dePamphilis BMC Plant Biology 2013, 13:9 (9 January 2013)

Abstract | Full text | PDF | PubMed

48.

Study protocol   Open Access

Cellular versus acellular matrix devices in treatment of diabetic foot ulcers: study protocol for a comparative efficacy randomized controlled trial

Hadar Lev-Tov, Chin-Shang Li, Sara Dahle, Roslyn Rivkah Isseroff Trials 2013, 14:8 (9 January 2013)

Abstract | Full text | PDF | PubMed

49.

Research article   Open Access

Injury-elicited stressors alter endogenous retrovirus expression in lymphocytes depending on cell type and source lymphoid organ

Kang-Hoon Lee, Debora Lim, Tajia Green, David Greenhalgh, Kiho Cho BMC Immunology 2013, 14:2 (5 January 2013)

Abstract | Full text | PDF | PubMed

50.

Research   Open Access

A specific family of interspersed repeats (SINEs) facilitates meiotic synapsis in mammals

Matthew E Johnson, Ross A Rowsey, Sofia Shirley, Catherine VandeVoort, Jeffrey Bailey, Terry Hassold Molecular Cytogenetics 2013, 6:1 (1 January 2013)

Abstract | Full text | PDF | PubMed

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