26.
Identification of significant periodic genes in microarray gene expression data
Jie
Chen
BMC Bioinformatics 2005, 6 :286 (30 November 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
An approach using both Bartlett's C-statistic and Fisher's G-statistic can successfully identity genes which are significantly periodic in microarray time series data.
27.
Evaluation of developmental phenotypes produced by morpholino antisense targeting of a sea urchin Runx gene
James
A
Coffman,
Carrie
Dickey-Sims,
Jeffrey
S
Haug,
John
J
McCarthy,
Anthony
J
Robertson
BMC Biology 2004, 2 :6 (7 May 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The sea urchin's Runx transcription factor is crucial both for embryonic development and for cell proliferation and differentiation, according to a study using `morpholino' antisense oligonucleotides to knock down gene expression.
28.
Global nucleosome distribution and the regulation of transcription in yeast
Sevinc
Ercan,
Michael
J
Carrozza,
Jerry
L
Workman
Genome Biology 2004, 5 :243 (30 September 2004)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Recent studies show that active regulatory regions of the yeast genome have a lower density of nucleosomes than other regions, and that there is an inverse correlation between nucleosome density and the transcription rate of a gene.
29.
Sea urchin vault structure, composition, and differential localization during development
Phoebe
L
Stewart,
Miriam
Makabi,
Jennifer
Lang,
Carrie
Dickey-Sims,
Anthony
J
Robertson,
James
A
Coffman,
Kathy
A
Suprenant
BMC Developmental Biology 2005, 5 :3 (14 February 2005)
Abstract | Full text | PDF | PubMed
30.
Chromatin reassembly following RNA polymerase II transcription
Swaminathan
Venkatesh,
Michaela
Smolle,
Hua
Li,
Madelaine
Gogol,
Ying
Zhang,
Florence
Laurens,
Michael
P
Washburn,
Jerry
L
Workman
Epigenetics & Chromatin 2013, 6 (Suppl 1):O27 (18 March 2013)
Full text | PDF
31.
Use of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1
Cécile
Delouis,
Philippe
Prochasson,
Madeleine
Laithier,
Olivier
Brison
BMC Molecular Biology 2005, 6 :8 (14 April 2005)
Abstract | Full text | PDF | PubMed
32.
A topological algorithm for identification of structural domains of proteins
Frank
Emmert-Streib,
Arcady
Mushegian
BMC Bioinformatics 2007, 8 :237 (3 July 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
33.
CBFβ is a facultative Runx partner in the sea urchin embryo
Anthony
J
Robertson,
Carrie
Dickey-Sims,
Andrew
Ransick,
Dawn
E
Rupp,
John
J
McCarthy,
James
A
Coffman
BMC Biology 2006, 4 :4 (9 February 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Like its mammalian homologs, sea urchin Core Binding Factor beta binds to a Runx partner, but although Runt-1 deficiency affects embryonic differentiation and cell survival, CBFbeta knockdown affects only differentiation.
34.
Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo
Carrie
Dickey-Sims,
Anthony
J
Robertson,
Dawn
E
Rupp,
John
J
McCarthy,
James
A
Coffman
BMC Biology 2005, 3 :18 (2 August 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Sea urchin embryonic knockdown of either Runx protein or protein kinase C causes extensive apoptosis, while Runx deficiency is rescued by inhibition of caspase-3 and by PKC mRNA injection, providing evidence that Runx maintains PKC levels to ensure cell survival.
35.
Characterization of the minimum domain required for targeting budding yeast myosin II to the site of cell division
Ida
MB
Lister,
Nicola
J
Tolliday,
Rong
Li
BMC Biology 2006, 4 :19 (26 June 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The budding yeast myosin II protein Myo1 is likely to exist as a trimer and within the Myo1 minimum localization domain as now defined, the hinge region is required for contraction of the contractile ring during cytokinesis.
36.
Histones: should I stay or should I go?
Bing
Li,
Chun
Ruan,
Jerry
L
Workman
Genome Biology 2005, 6 :306 (14 January 2005)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A report on the American Society for Biochemistry and Molecular Biology symposium 'Transcriptional Regulation by Chromatin and RNA polymerase II', Lake Tahoe, USA, 29 October-1 November 2004.
37.
Chromatin dynamics rule the genome
Samantha
G
Pattenden,
Mark
JK
Chandy,
José
L
Gutiérrez,
Jerry
L
Workman
Genome Biology 2005, 6 :355 (31 October 2005)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A report on the FASEB Summer Research Conference 'Chromatin and Transcription', Snowmass, USA, 9-14 July 2005.
38.
Detecting epistatic interactions contributing to human gene expression using the CEPH family data
Hua
Li,
Guimin
Gao,
Jian
Li,
Grier
P
Page,
Kui
Zhang
BMC Proceedings 2007, 1 (Suppl 1):S67 (18 December 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
39.
Systems biology of bacteriophage proteins and new dimensions of the virus world discovered through metagenomics
David
M
Kristensen,
Arcady
R
Mushegian,
Eugene
V
Koonin
Genome Biology 2011, 12 (Suppl 1):P9 (19 September 2011)
Full text | PDF
The Stowers Institute for Medical Research seeks more effective means of preventing and curing disease through basic research on genes and proteins that control fundamental processes of cellular life. Scientists at the Institute study the way genes determine biological fate and how they can be altered to prevent or slow disease.
