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1.

Commentary   Subscription

Antibiotics for the critically ill: more than just selecting appropriate initial therapy

Marin H Kollef Critical Care 2013, 17:146 (23 May 2013)

Abstract | Full text | PDF

2.

Research article   Open Access

Hyperglycemia as a risk factor for the development of retinopathy of prematurity

Shakir Mohamed, Jeffrey C Murray, John M Dagle, Tarah Colaizy BMC Pediatrics 2013, 13:78 (16 May 2013)

Abstract | Provisional PDF | PubMed

3.

Research article   Open Access

Structural and functional annotation of the porcine immunome

Harry D Dawson, Jane E Loveland, Géraldine Pascal, James GR Gilbert, Hirohide Uenishi, Katherine M Mann, Yongming Sang, Jie Zhang, Denise Carvalho-Silva, Toby Hunt, Matthew Hardy, Zhiliang Hu, Shu-Hong Zhao, Anna Anselmo, Hiroki Shinkai, Celine Chen, Bouabid Badaoui, Daniel Berman, Clara Amid, Mike Kay, David Lloyd, Catherine Snow, Takeya Morozumi, Ryan Pei-Yen Cheng, Megan Bystrom, Ronan Kapetanovic, John C Schwartz, Ranjit Kataria, Matthew Astley, Eric Fritz et al. BMC Genomics 2013, 14:332 (15 May 2013)

Abstract | Full text | PDF | PubMed

4.

Debate   Open Access

Depression as a risk factor for adverse outcomes in coronary heart disease

Kenneth E Freedland, Robert M Carney BMC Medicine 2013, 11:131 (15 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Kenneth Freedland and Robert Carney argue that depression predicts coronary heart disease (CHD) but better methods are required to ascertain whether depression is a causal risk factor for CHD, which could help determine treatment strategies for CVD prevention.

5.

Research article   Open Access

Normal cognition in transgenic BRI2-Aβ mice

Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W Dickson, David R Borchelt, Todd Golde, Christopher Janus Molecular Neurodegeneration 2013, 8:15 (12 May 2013)

Abstract | Full text | PDF | PubMed

6.

Research   Open Access

Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis

Katherine C Chang, Carey-Ann Burnham, Stephanie M Compton, David P Rasche, Richard J Mazuski, Jacquelyn S Macdonough, Jacqueline Unsinger, Alan J Korman, Jonathan M Green, Richard S Hotchkiss Critical Care 2013, 17:R85 (11 May 2013)

Abstract | Provisional PDF | PubMed

7.

Research article   Open Access Highly Accessed

Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital

Jonas Marschall, Marilyn L Piccirillo, Betsy Foxman, Lixin Zhang, David K Warren, Jeffrey P Henderson, BMC Infectious Diseases 2013, 13:213 (10 May 2013)

Abstract | Full text | PDF | PubMed

8.

Research   Open Access

A retrospective cross-sectional study: fresh cycle endometrial thickness is a sensitive predictor of inadequate endometrial thickness in frozen embryo transfer cycles

Patricia T Jimenez, Samantha B Schon, Randall R Odem, Valerie S Ratts, Emily S Jungheim Reproductive Biology and Endocrinology 2013, 11:35 (10 May 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Phenotypic characteristics of early Wolfram syndrome

Bess A Marshall, M Alan Permutt, Alexander R Paciorkowski, James Hoekel, Roanne Karzon, Jon Wasson, Amy Viehover, Neil H White, Joshua S Shimony, Linda Manwaring, Paul Austin, Timothy E Hullar, Tamara Hershey, Orphanet Journal of Rare Diseases 2013, 8:64 (27 April 2013)

Abstract | Full text | PDF

10.

Research article   Open Access

Using geographic methods to inform cancer screening interventions for South Asians in Ontario, Canada

Aisha K Lofters, Piotr Gozdyra, Rebecca Lobb BMC Public Health 2013, 13:395 (26 April 2013)

Abstract | Full text | PDF | PubMed

11.

Opinion   Subscription Highly Accessed

Sixty years of genome biology

W Doolittle, Peter Fraser, Mark B Gerstein, Brenton R Graveley, Steven Henikoff, Curtis Huttenhower, Alicia Oshlack, Chris P Ponting, John L Rinn, Michael C Schatz, Jernej Ule, Detlef Weigel, George M Weinstock Genome Biology 2013, 14:113 (25 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Members of Genome Biology's Editorial Board select their highlights from the 60 years of genome biology that followed the double helix

12.

Methodology   Open Access

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

Jason D Ulrich, Jack M Burchett, Jessica L Restivo, Dorothy R Schuler, Philip B Verghese, Thomas E Mahan, Gary E Landreth, Joseph M Castellano, Hong Jiang, John R Cirrito, David M Holtzman Molecular Neurodegeneration 2013, 8:13 (19 April 2013)

Abstract | Full text | PDF | PubMed

13.

Reviewer acknowledgement   Open Access

Journal of Ovarian Research reviewer acknowledgement 2012

David T Curiel, Sham S Kakar, Stefano Palomba, Benjamin K Tsang Journal of Ovarian Research 2013, 6:16 (16 April 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Within-host evolution of Brucella canis during a canine brucellosis outbreak in a kennel

Miklós Gyuranecz, Brandy D Rannals, Christina A Allen, Szilárd Jánosi, Paul S Keim, Jeffrey T Foster BMC Veterinary Research 2013, 9:76 (12 April 2013)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access Highly Accessed

Neuropathic midfoot deformity: associations with ankle and subtalar joint motion

David R Sinacore, David J Gutekunst, Mary K Hastings, Michael J Strube, Kathryn L Bohnert, Fred W Prior, Jeffrey E Johnson Journal of Foot and Ankle Research 2013, 6:11 (25 March 2013)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access

Using concept mapping in the knowledge-to-action process to compare stakeholder opinions on barriers to use of cancer screening among South Asians

Rebecca Lobb, Andrew D Pinto, Aisha Lofters Implementation Science 2013, 8:37 (23 March 2013)

Abstract | Full text | PDF | PubMed

17.

Research   Open Access

Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat

Xianghong Arakaki, Paige McCleary, Matthew Techy, Jiarong Chiang, Linus Kuo, Alfred N Fonteh, Brian Armstrong, Dan Levy, Michael G Harrington Fluids and Barriers of the CNS 2013, 10:14 (14 March 2013)

Abstract | Full text | PDF | PubMed

18.

Research   Open Access Highly Accessed

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes

Adam D Ewing, Tracy J Ballinger, Dent Earl, Christopher C Harris, Li Ding, Richard K Wilson, David Haussler Genome Biology 2013, 14:R22 (13 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An analysis of gene retrocopy insertion polymorphisms in the germlines of individual humans, chimpanzees and mice, and in cancerous somatic tissues

19.

Research article   Open Access

DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs

Cynthia L Innes, Jill E Hesse, Stela S Palii, Beth A Helmink, Abigail J Holub, Barry P Sleckman, Richard S Paules BMC Genomics 2013, 14:163 (12 March 2013)

Abstract | Full text | PDF | PubMed

20.

Short report   Open Access Highly Accessed

Developing the next generation of dissemination and implementation researchers: insights from initial trainees

Katherine A Stamatakis, Wynne E Norton, Shannon W Stirman, Cathy Melvin, Ross C Brownson Implementation Science 2013, 8:29 (12 March 2013)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access

Recruitment and retention of participants in a pragmatic randomized intervention trial at three community health clinics: Results and lessons learned

Erica T Warner, Russell E Glasgow, Karen M Emmons, Gary G Bennett, Sandy Askew, Bernard Rosner, Graham A Colditz BMC Public Health 2013, 13:192 (6 March 2013)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access

Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration

Liangping Yuan, Hongying Zhang, Jingbo Liu, Joshua B Rubin, Yoon-Jae Cho, Hui Kuo Shu, Matthew Schniederjan, Tobey J MacDonald Molecular Cancer 2013, 12:18 (5 March 2013)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access

Quantification of heterogeneity observed in medical images

Frank J Brooks, Perry W Grigsby BMC Medical Imaging 2013, 13:7 (2 March 2013)

Abstract | Provisional PDF | PubMed

24.

Research article   Open Access

A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX

Jay Pendse, Prasanna V Ramachandran, Jianbo Na, Narisu Narisu, Jill L Fink, Ross L Cagan, Francis S Collins, Thomas J Baranski BMC Genomics 2013, 14:136 (27 February 2013)

Abstract | Full text | PDF | PubMed

25.

Research article   Open Access

Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora

Esley Heizer, Dante S Zarlenga, Bruce Rosa, Xin Gao, Robin B Gasser, Jessie De Graef, Peter Geldhof, Makedonka Mitreva BMC Genomics 2013, 14:118 (22 February 2013)

Abstract | Full text | PDF | PubMed

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