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101.

Research article   Open Access Highly Accessed

Rapid fixation of non-native alleles revealed by genome-wide SNP analysis of hybrid tiger salamanders

Benjamin M Fitzpatrick, Jarrett R Johnson, D Kevin Kump, H Bradley Shaffer, Jeramiah J Smith, S Randal Voss BMC Evolutionary Biology 2009, 9:176 (24 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In hybrid zones, introgression of a few strongly selected alleles from Barred Tiger Salamanders into the endangered Californian Tiger Salamander population might make preservation of genetically distinct populations of the endangered species difficult.

102.

Research   Open Access

Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase

Brian TD Tobe, Ana A Kitazono, Jacqueline S Garcia, Renee A Gerber, Brooke J Bevis, John S Choy, Daniel Chasman, Stephen J Kron Cell Division 2009, 4:12 (1 July 2009)

Abstract | Full text | PDF | PubMed

103.

Research   Open Access

Leucine modulation of mitochondrial mass and oxygen consumption in skeletal muscle cells and adipocytes

Xiaocun Sun, Michael B Zemel Nutrition & Metabolism 2009, 6:26 (5 June 2009)

Abstract | Full text | PDF | PubMed

104.

Methodology   Open Access Highly Accessed

The FAST technique: a simplified Agrobacterium-based transformation method for transient gene expression analysis in seedlings of Arabidopsis and other plant species

Jian-Feng Li, Eunsook Park, Albrecht G von Arnim, Andreas Nebenführ Plant Methods 2009, 5:6 (20 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

105.

Research article   Open Access Highly Accessed

Frequency-dependent selection by wild birds promotes polymorphism in model salamanders

Benjamin M Fitzpatrick, Kim Shook, Reuben Izally BMC Ecology 2009, 9:12 (8 May 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Birds attack salamander models with or without a stripe on their back with a frequency that depends on how common each type is, suggesting that predation may maintain variation in prey color and patterning.

106.

Research article   Open Access

The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota

Iain J Anderson, Lakshmi Dharmarajan, Jason Rodriguez, Sean Hooper, Iris Porat, Luke E Ulrich, James G Elkins, Kostas Mavromatis, Hui Sun, Miriam Land, Alla Lapidus, Susan Lucas, Kerrie Barry, Harald Huber, Igor B Zhulin, William B Whitman, Biswarup Mukhopadhyay, Carl Woese, James Bristow, Nikos Kyrpides BMC Genomics 2009, 10:145 (2 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

107.

Research article   Open Access

The relative ages of ectomycorrhizal mushrooms and their plant hosts estimated using Bayesian relaxed molecular clock analyses

David S Hibbett, P Brandon Matheny BMC Biology 2009, 7:13 (10 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The ancestor of Agaricomycete fungi that form ectomycorrhizal symbioses with woody plants was free living before forming several independent associations with gymnosperms as it is of more ancient origin than any of its potential hosts.

108.

Research article   Open Access

A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation

Reza Mobini, Bengt A Andersson, Jonas Erjefält, Mirjana Hahn-Zoric, Michael A Langston, Andy D Perkins, Lars Cardell, Mikael Benson BMC Systems Biology 2009, 3:19 (12 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A strategy of identifying modules of co-expressed and interacting genes in complex disorders can be used to discover novel disease genes, and has been used to demonstrate the important role of the gene IL7R in allergy.

109.

Research Article   Open Access

Reconstructing Generalized Logical Networks of Transcriptional Regulation in Mouse Brain from Temporal Gene Expression Data

Mingzhou(Joe) Song, Chris K Lewis, Eric R Lance, Elissa J Chesler, Roumyana Kirova Yordanova, Michael A Langston, Kerrie H Lodowski, Susan E Bergeson EURASIP Journal on Bioinformatics and Systems Biology 2009, 2009:545176 (27 January 2009)

Abstract | Full text | PDF

110.

Research   Open Access

n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes

Patrick Wortman, Yuko Miyazaki, Nishan S Kalupahana, Suyeon Kim, Melissa Hansen-Petrik, Arnold M Saxton, Kate J Claycombe, Brynn H Voy, Jay Whelan, Naima Moustaid-Moussa Nutrition & Metabolism 2009, 6:5 (21 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

111.

Review   Open Access Highly Accessed

Feeling manipulated: cytomegalovirus immune manipulation

Mindy Miller-Kittrell, Tim E Sparer Virology Journal 2009, 6:4 (9 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

112.

Research article   Open Access

Local and regional factors influence the structure of treehole metacommunities

Christopher J Paradise, Jarrod D Blue, John Q Burkhart, Justin Goldberg, Lauren Harshaw, Katherine D Hawkins, Benjamin Kegan, Tyler Krentz, Leslie Smith, Shawn Villalpando BMC Ecology 2008, 8:22 (19 December 2008)

Abstract | Full text | PDF | PubMed

113.

Research   Open Access Highly Accessed

Effects of dairy intake on weight maintenance

Michael B Zemel, Joseph E Donnelly, Bryan K Smith, Debra K Sullivan, Joanna Richards, Danielle Morgan-Hanusa, Matthew S Mayo, Xiaocun Sun, Galen Cook-Wiens, Bruce W Bailey, Emily L Van Walleghen, Richard A Washburn Nutrition & Metabolism 2008, 5:28 (24 October 2008)

Abstract | Full text | PDF | PubMed

114.

Methodology   Open Access

Mutational optimization of the coelenterazine-dependent luciferase from Renilla

Jongchan Woo, Albrecht G von Arnim Plant Methods 2008, 4:23 (30 September 2008)

Abstract | Full text | PDF | PubMed

115.

Oral presentation   Open Access

Efficacy of an ankle orthosis with a subtalar locking system in restricting ankle kinetics and kinematics in lateral cutting

Songning Zhang, Michael Wortley, Qingjian Chen, Julia Freedman, Casey Riley Journal of Foot and Ankle Research 2008, 1(Suppl 1):O19 (26 September 2008)

Full text | PDF

116.

Research   Open Access

Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production

James D Godkin, Mary P Roberts, Mona Elgayyar, Wei Guan, Patricia K Tithof Reproductive Biology and Endocrinology 2008, 6:44 (23 September 2008)

Abstract | Full text | PDF | PubMed

117.

Short report   Open Access

Genome sequence of the Bacteroides fragilis phage ATCC 51477-B1

Shawn A Hawkins, Alice C Layton, Steven Ripp, Dan Williams, Gary S Sayler Virology Journal 2008, 5:97 (18 August 2008)

Abstract | Full text | PDF | PubMed

118.

Research article   Open Access

Transcriptional responses of Arabidopsis thaliana plants to As (V) stress

Jason M Abercrombie, Matthew D Halfhill, Priya Ranjan, Murali R Rao, Arnold M Saxton, Joshua S Yuan, C Neal Stewart BMC Plant Biology 2008, 8:87 (6 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

119.

Research Article   Open Access

Statistical Analysis of Multipath Fading Channels Using Generalizations of Shot Noise

CharalambosD Charalambous, SeddikM Djouadi, Christos Kourtellaris EURASIP Journal on Wireless Communications and Networking 2008, 2008:186020 (29 July 2008)

Abstract | Full text | PDF

120.

Poster presentation   Open Access

Using a literature-based NMF model for discovering gene functional relationships

Elina Tjioe, Michael Berry, Ramin Homayouni, Kevin Heinrich BMC Bioinformatics 2008, 9(Suppl 7):P1 (8 July 2008)

Full text | PDF

121.

Research   Open Access

Differential transferrin expression in placentae from normal and abnormal pregnancies: a pilot study

Alena Kralova, Marta Svetlikova, Jindrich Madar, Zdena Ulcova-Gallova, Antonin Bukovsky, Jana Peknicova Reproductive Biology and Endocrinology 2008, 6:27 (2 July 2008)

Abstract | Full text | PDF | PubMed

122.

Research article   Open Access

Hybridization produces novelty when the mapping of form to function is many to one

Nicholas F Parnell, C Darrin Hulsey, J Todd Streelman BMC Evolutionary Biology 2008, 8:122 (28 April 2008)

Abstract | Full text | PDF | PubMed

123.

Research Article   Open Access

Neural Network Adaptive Control for Discrete-Time Nonlinear Nonnegative Dynamical Systems

WassimM Haddad, VijaySekhar Chellaboina, Qing Hui, Tomohisa Hayakawa Advances in Difference Equations 2008, 2008:868425 (9 April 2008)

Abstract | Full text | PDF

124.

Research Article   Open Access

Asymptotic Analysis of Large Cooperative Relay Networks Using Random Matrix Theory

Husheng Li, Z Han, H Poor EURASIP Journal on Advances in Signal Processing 2008, 2008:235867 (5 March 2008)

Abstract | Full text | PDF

125.

Methodology   Open Access

NFU-Enabled FASTA: moving bioinformatics applications onto wide area networks

Erich J Baker, Guan N Lin, Huadong Liu, Ravi Kosuri Source Code for Biology and Medicine 2007, 2:8 (26 November 2007)

Abstract | Full text | PDF | PubMed

126.

Research   Open Access

Home grocery delivery improves the household food environments of behavioral weight loss participants: Results of an 8-week pilot study

Amy A Gorin, Hollie A Raynor, Heather M Niemeier, Rena R Wing International Journal of Behavioral Nutrition and Physical Activity 2007, 4:58 (14 November 2007)

Abstract | Full text | PDF | PubMed

127.

Proceedings   Open Access Highly Accessed

Statistical tools for transgene copy number estimation based on real-time PCR

Joshua S Yuan, Jason Burris, Nathan R Stewart, Ayalew Mentewab, C Neal Stewart BMC Bioinformatics 2007, 8(Suppl 7):S6 (1 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

128.

Methodology article   Open Access

Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework

Michael A Gilchrist, Hong Qin, Russell Zaretzki BMC Bioinformatics 2007, 8:403 (18 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

129.

Research article   Open Access

Genomic and microarray analysis of aromatics degradation in Geobacter metallireducens and comparison to a Geobacter isolate from a contaminated field site

Jessica E Butler, Qiang He, Kelly P Nevin, Zhili He, Jizhong Zhou, Derek R Lovley BMC Genomics 2007, 8:180 (19 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

130.

Research   Open Access

Distinct phospholipase A2 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial cells

Patricia K Tithof, Mary P Roberts, Wei Guan, Mona Elgayyar, James D Godkin Reproductive Biology and Endocrinology 2007, 5:16 (25 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

131.

Research article   Open Access

Risk factors of gastrointestinal nematode parasite infections in small ruminants kept in smallholder mixed farms in Kenya

Agricola Odoi, Joseph M Gathuma, Charles K Gachuiri, Amos Omore BMC Veterinary Research 2007, 3:6 (20 April 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The grazing system and farmer education affect the success of deworming strategies against nematode infections in sheep and goats in Kenya.

132.

Research   Open Access

On the functions of the h subunit of eukaryotic initiation factor 3 in late stages of translation initiation

Byung-Hoon Kim, Xue Cai, Justin N Vaughn, Albrecht G von Arnim Genome Biology 2007, 8:R60 (17 April 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Reporter transgene assays and comparative polysome-microarray analysis reveal that the intact h subunit of Arabidopsis eIF3 contributes to efficient translation initiation on mRNA leader sequences harbouring multiple uORFs.

133.

Research Article   Open Access

A Reconfigurable FPGA System for Parallel Independent Component Analysis

Hongtao Du, Hairong Qi EURASIP Journal on Embedded Systems 2006, 2006:023025 (19 November 2006)

Abstract | Full text | PDF

134.

Research article   Open Access Highly Accessed

RNA:protein ratio of the unicellular organism as a characteristic of phosphorous and nitrogen stoichiometry and of the cellular requirement of ribosomes for protein synthesis

Tatiana V Karpinets, Duncan J Greenwood, Carl E Sams, John T Ammons BMC Biology 2006, 4:30 (5 September 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The link between decreased ratios of RNA:protein and phosphorus:nitrogen and lower growth rates in microorganisms is explained by changes in protein synthesis efficiency, connecting the nutrient dynamics of complex ecosystems to cellular mechanisms.

135.

Research article   Open Access

Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells

Madhu S Dhar, Howard K Plummer BMC Physiology 2006, 6:8 (31 August 2006)

Abstract | Full text | PDF | PubMed

136.

Original basic research   Open Access

Soluble fibrin inhibits monocyte adherence and cytotoxicity against tumor cells: implications for cancer metastasis

John P Biggerstaff, Brandy Weidow, Jacqueline Vidosh, Judith Dexheimer, Shonak Patel, Pretesh Patel Thrombosis Journal 2006, 4:12 (22 August 2006)

Abstract | Full text | PDF | PubMed | 1 comment

137.

Methodology article   Open Access

Enumeration of leukocyte infiltration in solid tumors by confocal laser scanning microscopy

J Biggerstaff, B Weidow, A Amirkhosravi, JL Francis BMC Immunology 2006, 7:16 (21 July 2006)

Abstract | Full text | PDF | PubMed

138.

Research article   Open Access

A statistical investigation of normal regional intra-subject heterogeneity of brain metabolism and perfusion by F-18 FDG and O-15 H2O PET imaging

Ching-yee Wong, Joseph Thie, Marianne Gaskill, Richard Ponto, Jack Hill, Hai-yan Tian, Helena Balon, Dafang Wu, Darlene Fink-Bennett, Conrad Nagle BMC Nuclear Medicine 2006, 6:4 (12 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

139.

Research Article   Open Access

Stochastic Power Control for Time-Varying Long-Term Fading Wireless Networks

Mohammed M Olama, Seddik M Djouadi, Charalambos D Charalambous EURASIP Journal on Advances in Signal Processing 2006, 2006:089864 (29 June 2006)

Abstract | Full text | PDF

140.

Methodology   Open Access Highly Accessed

A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene

Larry A Hanson, Mary R Rudis, Marcia Vasquez-Lee, Roy D Montgomery Virology Journal 2006, 3:28 (11 April 2006)

Abstract | Full text | PDF | PubMed

141.

Review   Open Access

Recent developments in primer design for DNA polymorphism and mRNA profiling in higher plants

Xiaohan Yang, Brian E Scheffler, Leslie A Weston Plant Methods 2006, 2:4 (1 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

142.

Methodology article   Open Access Highly Accessed

Statistical analysis of real-time PCR data

Joshua S Yuan, Ann Reed, Feng Chen, C Neal Stewart BMC Bioinformatics 2006, 7:85 (22 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

143.

Research article   Open Access Highly Accessed

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice

Edward J Michaud, Cymbeline T Culiat, Mitchell L Klebig, Paul E Barker, KT Cain, Debra J Carpenter, Lori L Easter, Carmen M Foster, Alysyn W Gardner, ZY Guo, Kay J Houser, Lori A Hughes, Marilyn K Kerley, Zhaowei Liu, Robert E Olszewski, Irina Pinn, Ginger D Shaw, Sarah G Shinpock, Ann M Wymore, Eugene M Rinchik, Dabney K Johnson BMC Genomics 2005, 6:164 (21 November 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

144.

Research Article   Open Access

Thermodynamic modeling, energy equipartition, and nonconservation of entropy for discrete-time dynamical systems

Wassim M Haddad, Qing Hui, Sergey G Nersesov, Vijaysekhar Chellaboina Advances in Difference Equations 2005, 2005:248040 (27 September 2005)

Abstract | Full text | PDF

145.

Research article   Open Access

Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines

Howard K Plummer, Madhu S Dhar, Maria Cekanova, Hildegard M Schuller BMC Cancer 2005, 5:104 (18 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

146.

Debate   Open Access Highly Accessed

Can ovarian infertility be treated with bone marrow- or ovary-derived germ cells?

Antonin Bukovsky Reproductive Biology and Endocrinology 2005, 3:36 (15 August 2005)

Abstract | Full text | PDF | PubMed

147.

Research   Open Access Highly Accessed

Oogenesis in cultures derived from adult human ovaries

Antonin Bukovsky, Marta Svetlikova, Michael R Caudle Reproductive Biology and Endocrinology 2005, 3:17 (5 May 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments |  Editor’s summary

Culturing ovarian surface epithelial cells in the presence of an oestrogen-containing medium yields mature oocytes which are capable of being fertilised for use in fertility treatments and stem cell research.

148.

Research   Open Access

Expression of the α7 nicotinic acetylcholine receptor in human lung cells

Howard K Plummer, Madhu Dhar, Hildegard M Schuller Respiratory Research 2005, 6:29 (4 April 2005)

Abstract | Full text | PDF | PubMed

149.

Database   Open Access Highly Accessed

Floral gene resources from basal angiosperms for comparative genomics research

Victor A Albert, Douglas E Soltis, John E Carlson, William G Farmerie, P Kerr Wall, Daniel C Ilut, Teri M Solow, Lukas A Mueller, Lena L Landherr, Yi Hu, Matyas Buzgo, Sangtae Kim, Mi-Jeong Yoo, Michael W Frohlich, Rafael Perl-Treves, Scott E Schlarbaum, Barbara J Bliss, Xiaohong Zhang, Steven D Tanksley, David G Oppenheimer, Pamela S Soltis, Hong Ma, Claude W dePamphilis, James H Leebens-Mack BMC Plant Biology 2005, 5:5 (30 March 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Initial findings from the Floral Genome Project demonstrate the utility of basal angiosperm EST datasets for revealing the basic floral transcriptome and addressing evolutionary genomic areas of research.

150.

Database   Open Access

GeneKeyDB: A lightweight, gene-centric, relational database to support data mining environments

SA Kirov, X Peng, E Baker, D Schmoyer, B Zhang, J Snoddy BMC Bioinformatics 2005, 6:72 (24 March 2005)

Abstract | Full text | PDF | PubMed

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