1.
jMOSAiCS: joint analysis of multiple ChIP-seq datasets
Xin
Zeng,
Rajendran
Sanalkumar,
Emery
H
Bresnick,
Hongda
Li,
Qiang
Chang,
Sunduz
Keles
Genome Biology 2013, 14 :R38 (29 April 2013)
Abstract | Provisional PDF
|
Editor’s summary
A novel probabilistic method for jointly analyzing multiple ChIP-seq datasets offers an improvement over chromHMM
2.
Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study
Yaseen
M
Arabi,
Saqib
I
Dara,
Hani
M
Tamim,
Asgar
H
Rishu,
Abderrezak
Bouchama,
Mohammad
K
Khedr,
Daniel
Feinstein,
Joseph
E
Parrillo,
Kenneth
E
Wood,
Sean
P
Keenan,
Sergio
Zanotti,
Greg
Martinka,
Aseem
Kumar,
Anand
Kumar,
Critical Care 2013, 17 :R72 (17 April 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The obesity paradox (lower mortality in the obese) is observed in patients admitted to intensive care with septic shock in a large international retrospective cohort study.
3.
The role for scientists in tackling food insecurity and climate change
John
R
Beddington,
Mohammed
Asaduzzaman,
Megan
E
Clark,
Adrian
Bremauntz,
Marion
D
Guillou,
Molly
M
Jahn,
Erda
Lin,
Tekalign
Mamo,
Christine
Negra,
Carlos
A
Nobre,
Robert
J
Scholes,
Rita
Sharma,
Nguyen
Van Bo,
Judi
Wakhungu
Agriculture & Food Security 2012, 1 :10 (20 July 2012)
Abstract | Full text | PDF |
4.
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo
Li,
Colin
N
Dewey
BMC Bioinformatics 2011, 12 :323 (4 August 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
RSEM is a new user-friendly software tool for quantifying transcript abundance from RNA-seq data that does not rely on a reference genome and is particularly useful for quantification with de novo transcriptome assemblies
5.
Bioconductor: open software development for computational biology and bioinformatics
Robert
C
Gentleman,
Vincent
J
Carey,
Douglas
M
Bates,
Ben
Bolstad,
Marcel
Dettling,
Sandrine
Dudoit,
Byron
Ellis,
Laurent
Gautier,
Yongchao
Ge,
Jeff
Gentry,
Kurt
Hornik,
Torsten
Hothorn,
Wolfgang
Huber,
Stefano
Iacus,
Rafael
Irizarry,
Friedrich
Leisch,
Cheng
Li,
Martin
Maechler,
Anthony
J
Rossini,
Gunther
Sawitzki,
Colin
Smith,
Gordon
Smyth,
Luke
Tierney,
Jean
YH
Yang,
Jianhua
Zhang
Genome Biology 2004, 5 :R80 (15 September 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
A detailed description of the aims and methods of the Bioconductor project, an initiative for the collaborative creation of extensible software for computational biology and bioinformatics.
6.
An information integration theory of consciousness
Giulio
Tononi
BMC Neuroscience 2004, 5 :42 (2 November 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central |
|
Editor’s summary
A new theory proposes that consciousness corresponds to the capacity of a system to integrate information, accounting for several neurobiological aspects of consciousness.
7.
Agriculture & Food Security : first anniversary
Malcolm
Elliott,
Molly
Jahn,
Magdy
Madkour
Agriculture & Food Security 2013, 2 :7 (23 April 2013)
Abstract | Full text | PDF
8.
Neutrophil necrosis and annexin 1 degradation associated with airway inflammation in lung transplant recipients with cystic fibrosis
Francis H
C
Tsao,
Zhuzai
Xiang,
Adnan
Abbasi,
Keith
C
Meyer
BMC Pulmonary Medicine 2012, 12 :44 (17 August 2012)
Abstract | Full text | PDF | PubMed
9.
What does the concept of the stem cell niche really mean today?
Arthur
D
Lander,
Judith
Kimble,
Hans
Clevers,
Elaine
Fuchs,
Didier
Montarras,
Margaret
Buckingham,
Anne
L
Calof,
Andreas
Trumpp,
Thordur
Oskarsson
BMC Biology 2012, 10 :19 (9 March 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
How do current researchers view the stem cell niche? Eight experts from different fields provide their perspective, and ask how stem cells evolve in such an environment, launching a new Forum article type within the cross-journal collection on stem cells.
10.
Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence
Benoît
Remenant,
Bénédicte
Coupat-Goutaland,
Alice
Guidot,
Gilles
Cellier,
Emmanuel
Wicker,
Caitilyn
Allen,
Mark
Fegan,
Olivier
Pruvost,
Mounira
Elbaz,
Alexandra
Calteau,
Gregory
Salvignol,
Damien
Mornico,
Sophie
Mangenot,
Valérie
Barbe,
Claudine
Médigue,
Philippe
Prior
BMC Genomics 2010, 11 :379 (15 June 2010)
Abstract | Full text | PDF | PubMed
11.
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing
Sebastiaan
van Heesch,
Wigard
P
Kloosterman,
Nico
Lansu,
Frans-Paul
Ruzius,
Elizabeth
Levandowsky,
Clarence
C
Lee,
Shiguo
Zhou,
Steve
Goldstein,
David
C
Schwartz,
Timothy
T
Harkins,
Victor
Guryev,
Edwin
Cuppen
BMC Genomics 2013, 14 :257 (16 April 2013)
Abstract | Full text | PDF | PubMed
12.
Needs Assessment for cancer patients and their families
Kuang-Yi
Wen,
David
H
Gustafson
Health and Quality of Life Outcomes 2004, 2 :11 (26 February 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
13.
Alcohol use and HIV serostatus of partner predict high-risk sexual behavior among patients receiving antiretroviral therapy in South Western Uganda
Francis
Bajunirwe,
David
R
Bangsberg,
Ajay
K
Sethi
BMC Public Health 2013, 13 :430 (3 May 2013)
Abstract | Full text | PDF | PubMed
14.
Plant cell wall profiling by fast maximum likelihood reconstruction (FMLR) and region-of-interest (ROI) segmentation of solution-state 2D 1H--13C NMR spectra
Roger
A
Chylla,
Rebecca
Van Acker,
Hoon
Kim,
Ali
Azapira,
Purba
Mukerjee,
John
L
Markley,
Véronique
Storme,
Wout
Boerjan,
John
Ralph
Biotechnology for Biofuels 2013, 6 :45 (26 April 2013)
Abstract | Provisional PDF
| PubMed
15.
Lack of evidence of WNT3A as a candidate gene for congenital vertebral malformations
Nader
Ghebranious,
Cathleen
L
Raggio,
Robert
D
Blank,
Elizabeth
McPherson,
James
K
Burmester,
Lynn
Ivacic,
Kristen
Rasmussen,
Jennifer
Kislow,
Ingrid
Glurich,
F Stig
Jacobsen,
Thomas
Faciszewski,
Richard
M
Pauli,
Oheneba
Boachie-Adjei,
Philip
F
Giampietro
Scoliosis 2007, 2 :13 (23 September 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
16.
Cultivation conditions and the diffusion of oxygen into culture media: The rationale for the flask-to-medium ratio in microbiology
Greg
A
Somerville,
Richard
A
Proctor
BMC Microbiology 2013, 13 :9 (16 January 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
As laboratory technology increases in sophistication Greg Somerville and Richard Proctor highlight the importance of considering all bacterial culture conditions, such as the flask-to-medium ratio, when designing experiments, to ensure accuracy in the reporting of results.
17.
Syntenic relationships between cucumber (Cucumis sativus L.) and melon (C. melo L.) chromosomes as revealed by comparative genetic mapping
Dawei
Li,
Hugo
E
Cuevas,
Luming
Yang,
Yuhong
Li,
Jordi
Garcia-Mas,
Juan
Zalapa,
Jack
E
Staub,
Feishi
Luan,
Umesh
Reddy,
Xiaoming
He,
Zhenhui
Gong,
Yiqun
Weng
BMC Genomics 2011, 12 :396 (5 August 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
18.
Testing use of payers to facilitate evidence-based
practice adoption: protocol for a cluster-randomize
d
trial
Todd
Molfenter,
Jee-Seon
Kim,
Andrew
Quanbeck,
Terry
Patel-Porter,
Sandy
Starr,
Dennis
McCarty
Implementation Science 2013, 8 :50 (10 May 2013)
Abstract | Provisional PDF
| PubMed
19.
Improvement of the Oryza sativa Nipponbare reference genome using next generation sequence and optical map data
Yoshihiro
Kawahara,
Melissa
de la Bastide,
John
P
Hamilton,
Hiroyuki
Kanamori,
W Richard
McCombie,
Shu
Ouyang,
David
C
Schwartz,
Tsuyoshi
Tanaka,
Jianzhong
Wu,
Shiguo
Zhou,
Kevin
L
Childs,
Rebecca
M
Davidson,
Haining
Lin,
Lina
Quesada-Ocampo,
Brieanne
Vaillancourt,
Hiroaki
Sakai,
Sung Shin
Lee,
Jungsok
Kim,
Hisataka
Numa,
Takeshi
Itoh,
C Robin
Buell,
Takashi
Matsumoto
Rice 2013, 6 :4 (6 February 2013)
Abstract | Full text | PDF
20.
Tegument protein control of latent herpesvirus establishment and animation
Rhiannon
R
Penkert,
Robert
F
Kalejta
Herpesviridae 2011, 2 :3 (8 February 2011)
Abstract | Full text | PDF | PubMed
21.
BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs
Michele
Carbone,
Laura
Ferris,
Francine
Baumann,
Andrea
Napolitano,
Christopher
A
Lum,
Erin
G
Flores,
Giovanni
Gaudino,
Amy
Powers,
Peter
Bryant-Greenwood,
Thomas
Krausz,
Elizabeth
Hyjek,
Rachael
Tate,
Joseph
Friedberg,
Tracey
Weigel,
Harvey
I
Pass,
Haining
Yang
Journal of Translational Medicine 2012, 10 :179 (30 August 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The presence of melanocytic tumors can provide physicians with a visual marker to identify individuals who may carry germline BAP1 mutations and so are at higher risk of developing melanoma and mesothelioma.
22.
Efficient isolation of live microglia with preserved phenotypes from adult mouse brain
Maria
Nikodemova,
Jyoti
J
Watters
Journal of Neuroinflammation 2012, 9 :147 (28 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
23.
Ryanodine receptors
E Michelle
Capes,
Randall
Loaiza,
Héctor
H
Valdivia
Skeletal Muscle 2011, 1 :18 (4 May 2011)
Abstract | Full text | PDF | PubMed
24.
Collagen density promotes mammary tumor initiation and progression
Paolo
P
Provenzano,
David
R
Inman,
Kevin
W
Eliceiri,
Justin
G
Knittel,
Long
Yan,
Curtis
T
Rueden,
John
G
White,
Patricia
J
Keely
BMC Medicine 2008, 6 :11 (28 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Increased stromal collagen density in mouse mammary tissue increases both tumor formation and tumor cell invasive and migratory properties by three fold; furthermore, a metabolic signature for flavin adenine dinucleotide is identified in invading metastatic cells.
25.
ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication
Shannon
Seidel,
James
Bruce,
Mathias
Leblanc,
Kuo-Fen
Lee,
Hung
Fan,
Paul
Ahlquist,
John AT
Young
Virology Journal 2013, 10 :130 (24 April 2013)
Abstract | Full text | PDF | PubMed