126.
Quantitative and qualitative assessment of structural magnetic resonance imaging data in a two-center study
Sima
Chalavi,
Andrew
Simmons,
Hildebrand
Dijkstra,
Gareth
J
Barker,
A A T Simone
Reinders
BMC Medical Imaging 2012, 12 :27 (6 August 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Pooling images in multi-centre MRI studies requires an optimized and standardized protocol for minimizing differences in sequence patterns.
127.
Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost
Yi
Li,
Armin
Sturm,
Phil
Cunningham,
Nicolas
R
Bury
BMC Evolutionary Biology 2012, 12 :137 (3 August 2012)
Abstract | Full text | PDF | PubMed
128.
Single breath-hold assessment of cardiac function using an accelerated 3D single breath-hold acquisition technique - comparison of an intravascular and extravascular contrast agent
Marcus
R
Makowski,
Andrea
J
Wiethoff,
Christian
HP
Jansen,
Sergio
Uribe,
Victoria
Parish,
Andreas
Schuster,
Rene
M
Botnar,
Aaron
Bell,
Christoph
Kiesewetter,
Reza
Razavi,
Tobias
Schaeffter,
Gerald
F
Greil
Journal of Cardiovascular Magnetic Resonance 2012, 14 :53 (31 July 2012)
Abstract | Full text | PDF | PubMed
129.
Screening for personality disorder in incarcerated adolescent boys: preliminary validation of an adolescent version of the standardised assessment of personality – abbreviated scale (SAPAS-AV)
Mickey
Kongerslev,
Paul
Moran,
Sune
Bo,
Erik
Simonsen
BMC Psychiatry 2012, 12 :94 (30 July 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
130.
Physical health symptoms reported by trafficked women receiving post-trafficking support in Moldova: prevalence, severity and associated factors
Siân
Oram,
Nicolae
V
Ostrovschi,
Viorel
I
Gorceag,
Mihai
A
Hotineanu,
Lilia
Gorceag,
Carolina
Trigub,
Melanie
Abas
BMC Women's Health 2012, 12 :20 (26 July 2012)
Abstract | Full text | PDF | PubMed
131.
Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature
Pietro
Invernizzi,
Maria
Alessio,
Daniel
S
Smyk,
Ana
Lleo,
Aurelio
Sonzogni,
Luca
Fabris,
Manila
Candusso,
Dimitrios
P
Bogdanos,
Raffaele
Iorio,
Giuliano
Torre
BMC Gastroenterology 2012, 12 :92 (20 July 2012)
Abstract | Full text | PDF | PubMed
132.
The diagnosis of urinary tract infections in young children (DUTY): protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness
Harriet
Downing,
Emma
Thomas-Jones,
Micaela
Gal,
Cherry-Ann
Waldron,
Jonathan
Sterne,
William
Hollingworth,
Kerenza
Hood,
Brendan
Delaney,
Paul
Little,
Robin
Howe,
Mandy
Wootton,
Alastair
Macgowan,
Christopher
C
Butler,
Alastair
D
Hay,
BMC Infectious Diseases 2012, 12 :158 (19 July 2012)
Abstract | Full text | PDF | PubMed
133.
Investigating the genetic and environmental bases of biases in threat recognition and avoidance in children with anxiety problems
Jennifer Y
F
Lau,
Kevin
Hilbert,
Robert
Goodman,
Alice
M
Gregory,
Daniel
S
Pine,
Essi
M
Viding,
Thalia
C
Eley
Biology of Mood & Anxiety Disorders 2012, 2 :12 (12 July 2012)
Abstract | Full text | PDF | PubMed
134.
Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers
Gareth
A
Wilson,
Pawandeep
Dhami,
Andrew
Feber,
Daniel
Cortázar,
Yuka
Suzuki,
Reiner
Schulz,
Primo
Schär,
Stephan
Beck
GigaScience 2012, 1 :3 (12 July 2012)
Abstract | Full text | PDF
|
Editor’s summary
MeDUSA is a novel MeDIP-seq-based methylation analysis pipeline, and all the tools and 18 mouse methylomes are available at GigaDB to test it out yourselves
135.
The effect of body position on compartmental intra-abdominal pressure following liver transplantation
Adrian
B
Cresswell,
Wayel
Jassem,
Parthi
Srinivasan,
Andreas
A
Prachalias,
Elizabeth
Sizer,
William
Burnal,
Georg
Auzinger,
Paolo
Muiesan,
Mohammed
Rela,
Nigel
D
Heaton,
Matthew
J
Bowles,
Julia
A
Wendon
Annals of Intensive Care 2012, 2 (Suppl 1):S12 (5 July 2012)
Abstract | Full text | PDF | PubMed
136.
ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
James
R
Perkins,
John
M
Dawes,
Steve
B
McMahon,
David
LH
Bennett,
Christine
Orengo,
Matthias
Kohl
BMC Genomics 2012, 13 :296 (2 July 2012)
Abstract | Full text | PDF | PubMed
137.
Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression
Emanuel
Severus,
Florian
Seemüller,
Michael
Berger,
Sandra
Dittmann,
Michael
Obermeier,
Andrea
Pfennig,
Michael
Riedel,
Sophia
Frangou,
Hans-Jürgen
Möller,
Michael
Bauer
BMC Medicine 2012, 10 :67 (2 July 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
In clinical trials for depression, blinded placebo use could influence outcome; Emanuel Severus et al. propose an alternative design whereby patients can choose to receive treatment and are informed of the benefits, in order to improve trial validity.
138.
Mass social contact interventions and their effect on mental health related stigma and intended discrimination
Sara
Evans-Lacko,
Jillian
London,
Sarah
Japhet,
Nicolas
Rüsch,
Clare
Flach,
Elizabeth
Corker,
Claire
Henderson,
Graham
Thornicroft
BMC Public Health 2012, 12 :489 (28 June 2012)
Abstract | Full text | PDF | PubMed
139.
Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice
Manu
Shankar-Hari,
Peter
S
Kruger,
Stefania
Di Gangi,
Damon
C
Scales,
Gavin
D
Perkins,
Danny
F
McAuley,
Marius
Terblanche
BMC Clinical Pharmacology 2012, 12 :13 (28 June 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Physicians in the UK, Australia and New Zealand report similar statin prescription practices and support conducting a trial to investigate whether statins can prevent the onset of new organ failure in patients with sepsis.
140.
Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response
Karen
Hodgson,
Shaista
Mufti,
Rudolf
Uher,
Peter
McGuffin
Genome Medicine 2012, 4 :52 (27 June 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Peter McGuffin and colleagues review recent GWASs of antidepressant response, and discuss factors that might contribute to variability in treatment outcomes and progress towards predicting responses.
141.
How good are we at implementing evidence to support the management of birth related perineal trauma? A UK wide survey of midwifery practice
Debra
E
Bick,
Khaled
M
Ismail,
Sue
Macdonald,
Peter
Thomas,
Sue
Tohill,
Christine
Kettle
BMC Pregnancy and Childbirth 2012, 12 :57 (25 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
142.
Detection of thrombus size and protein content by ex vivo magnetization transfer and diffusion weighted MRI
Alkystis
Phinikaridou,
Ye
Qiao,
Nick
Giordano,
James
A
Hamilton
Journal of Cardiovascular Magnetic Resonance 2012, 14 :45 (25 June 2012)
Abstract | Full text | PDF | PubMed
143.
Freestanding midwifery units versus obstetric units: does the effect of place of birth differ with level of social disadvantage?
Charlotte
Overgaard,
Morten
Fenger-Grøn,
Jane
Sandall
BMC Public Health 2012, 12 :478 (22 June 2012)
Abstract | Full text | PDF | PubMed
144.
Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses
Shetal
Arjan-Odedra,
Chad
M
Swanson,
Nathan
M
Sherer,
Steven
M
Wolinsky,
Michael
H
Malim
Retrovirology 2012, 9 :53 (22 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
MOV10 overexpression substantially decreased the production of infectious retrovirus particles, as well the propagation of LTR and non-LTR endogenous retroelements. Most significantly, RNAi-mediated silencing of endogenous MOV10 enhanced the replication of both LTR and non-LTR endogenous retroelements, but not the production of infectious retrovirus particles demonstrating that natural levels of MOV10 suppress retrotransposition, but have no impact on infection by exogenous retroviruses.
145.
Validating self-reported strokes in a longitudinal UK cohort study (Whitehall II): Extracting information from hospital medical records versus the Hospital Episode Statistics database
Annie
Britton,
Beverly
Milne,
Therese
Butler,
Adelaida
Sanchez-Galvez,
Martin
Shipley,
Anthony
Rudd,
Charles
DA Wolfe,
Ajay
Bhalla,
Eric
J
Brunner
BMC Medical Research Methodology 2012, 12 :83 (21 June 2012)
Abstract | Full text | PDF | PubMed
146.
Coronary collaterals and risk for restenosis after percutaneous coronary interventions: a meta-analysis
Pascal
Meier,
Andreas
Indermuehle,
Bertram
Pitt,
Tobias
Traupe,
Stefano
F
de Marchi,
Tom
Crake,
Guido
Knapp,
Alexandra
J
Lansky,
Christian
Seiler
BMC Medicine 2012, 10 :62 (21 June 2012)
Abstract | Full text | PDF | PubMed |
|
Editor’s summary
A meta-analysis finds that increased coronary collateral circulation after a heart attack augments the risk of restenosis after percutaneous coronary interventions (PCI), so could be a useful marker in risk stratification.
147.
Inter-study reproducibility of cardiovascular magnetic resonance myocardial feature tracking
Geraint
Morton,
Andreas
Schuster,
Roy
Jogiya,
Shelby
Kutty,
Philipp
Beerbaum,
Eike
Nagel
Journal of Cardiovascular Magnetic Resonance 2012, 14 :43 (21 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
148.
Prognostic signatures in breast cancer: correlation does not imply causation
Charlotte
Ng,
Britta
Weigelt,
Anita
Grigoriadis,
Jorge
S
Reis-Filho
Breast Cancer Research 2012, 14 :313 (19 June 2012)
Abstract | Full text | PDF | PubMed
149.
The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD) in children, adolescents and adults in UK primary care
Suzanne
McCarthy,
Lynda
Wilton,
Macey
L
Murray,
Paul
Hodgkins,
Philip
Asherson,
Ian
CK
Wong
BMC Pediatrics 2012, 12 :78 (19 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
150.
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
Matthew
N
Davies,
Manuela
Volta,
Ruth
Pidsley,
Katie
Lunnon,
Abhishek
Dixit,
Simon
Lovestone,
Cristian
Coarfa,
R Alan
Harris,
Aleksandar
Milosavljevic,
Claire
Troakes,
Safa
Al-Sarraj,
Richard
Dobson,
Leonard
C
Schalkwyk,
Jonathan
Mill
Genome Biology 2012, 13 :R43 (15 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
Differentially methylated regions are annotated using matched blood and brain samples from multiple individuals