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1.

Letter to the Editor   Open Access

A combination of mutations in AKR1D1 and SKIV2L in a family with severe infantile liver disease

Neil V Morgan, Jane L Hartley, Kenneth DR Setchell, Michael A Simpson, Rachel Brown, Louise Tee, Sian Kirkham, Shanaz Pasha, Richard C Trembath, Eamonn R Maher, Paul Gissen, Deirdre A Kelly Orphanet Journal of Rare Diseases 2013, 8:74 (16 May 2013)

Abstract | Full text | PDF | PubMed

2.

Research article   Open Access

An investigation of factors identified at birth in relation to anxiety and depression in old age: the Hordaland Health Study (HUSK)

Jens Christoffer Skogen, Robert Stewart, Arnstein Mykletun, Marit Knapstad, Simon Øverland BMC Psychiatry 2013, 13:136 (10 May 2013)

Abstract | Full text | PDF | PubMed

3.

Proceedings   Open Access

Locating tandem repeats in weighted sequences in proteins

Hui Zhang, Qing Guo, Costas S Iliopoulos BMC Bioinformatics 2013, 14(Suppl 8):S2 (9 May 2013)

Abstract | Full text | PDF

4.

Research article   Open Access Highly Accessed

Physical activity in older people: a systematic review

Fei Sun, Ian J Norman, Alison E While BMC Public Health 2013, 13:449 (6 May 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Attitudinal and perceptual factors in body image distortion: an exploratory study in patients with anorexia nervosa

Amanda Waldman, Rachel Loomes, Victoria A Mountford, Kate Tchanturia Journal of Eating Disorders 2013, 1:17 (3 May 2013)

Abstract | Full text | PDF

6.

Methodology article   Open Access Highly Accessed

Analysis of multiple phenotypes in genome-wide genetic mapping studies

Chen Suo, Timothea Toulopoulou, Elvira Bramon, Muriel Walshe, Marco Picchioni, Robin Murray, Jurg Ott BMC Bioinformatics 2013, 14:151 (2 May 2013)

Abstract | Full text | PDF | PubMed

7.

Methodology article   Open Access Highly Accessed

A data-driven approach to preprocessing Illumina 450K methylation array data

Ruth Pidsley, Chloe C Y Wong, Manuela Volta, Katie Lunnon, Jonathan Mill, Leonard C Schalkwyk BMC Genomics 2013, 14:293 (1 May 2013)

Abstract | Provisional PDF | PubMed

8.

Research article   Open Access

Human Papillomavirus-associated oropharyngeal cancer: an observational study of diagnosis, prevalence and prognosis in a UK population

Mererid Evans, Robert Newcombe, Alison Fiander, James Powell, Martin Rolles, Selvam Thavaraj, Max Robinson, Ned Powell BMC Cancer 2013, 13:220 (1 May 2013)

Abstract | Full text | PDF | PubMed

9.

Study protocol   Open Access

The E Sibling Project – exploratory randomised controlled trial of an online multi-component psychoeducational intervention for siblings of individuals with first episode psychosis

Jacqueline Sin, Claire Henderson, Vanessa Pinfold, Ian Norman BMC Psychiatry 2013, 13:123 (26 April 2013)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access

Evaluating complex interventions in End of Life Care: the MORECare Statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews

Irene J Higginson, Catherine J Evans, Gunn Grande, Nancy Preston, Myfanwy Morgan, Paul McCrone, Penney Lewis, Peter Fayers, Richard Harding, Matthew Hotopf, Scott A Murray, Hamid Benalia, Marjolein Gysels, Morag Farquhar, Chris Todd, BMC Medicine 2013, 11:111 (24 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Irene Higginson and colleagues present the MORECare statement, an evidence-based set of recommendations for improved research methods in end of life care, which aims to provide clear standards and guidance in this overlooked area of medicine.

11.

Research article   Open Access

NRXN1 deletions identified by array comparative genome hybridisation in a clinical case series – further understanding of the relevance of NRXN1 to neurodevelopmental disorders

Sarah Curran, Joo Wook Ahn, Hannah Grayton, David A Collier, Caroline Mackie Ogilvie Journal of Molecular Psychiatry 2013, 1:4 (23 April 2013)

Abstract | Full text | PDF

12.

Research article   Open Access

Management of irritable bowel syndrome in primary care: the results of an exploratory randomised controlled trial of mebeverine, methylcellulose, placebo and a self-management website

Hazel Everitt, Rona Moss-Morris, Alice Sibelli, Laura Tapp, Nicholas Coleman, Lucy Yardley, Peter Smith, Paul Little BMC Gastroenterology 2013, 13:68 (21 April 2013)

Abstract | Full text | PDF | PubMed

13.

Research article   Open Access

Discrimination in relation to parenthood reported by community psychiatric service users in the UK: a framework analysis

Debra Jeffery, Sarah Clement, Elizabeth Corker, Louise M Howard, Joanna Murray, Graham Thornicroft BMC Psychiatry 2013, 13:120 (20 April 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Assessments of mental capacity in psychiatric inpatients: a retrospective cohort study

Penelope F Brown, Alex D Tulloch, Charlotte Mackenzie, Gareth S Owen, George Szmukler, Matthew Hotopf BMC Psychiatry 2013, 13:115 (15 April 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access Highly Accessed

Is computerised CBT really helpful for adult depression?-A meta-analytic re-evaluation of CCBT for adult depression in terms of clinical implementation and methodological validity

Mirai So, Sosei Yamaguchi, Sora Hashimoto, Mitsuhiro Sado, Toshi A Furukawa, Paul McCrone BMC Psychiatry 2013, 13:113 (15 April 2013)

Abstract | Full text | PDF | PubMed

16.

Review   Open Access

The cognitive-interpersonal maintenance model of anorexia nervosa revisited: a summary of the evidence for cognitive, socio-emotional and interpersonal predisposing and perpetuating factors

Janet Treasure, Ulrike Schmidt Journal of Eating Disorders 2013, 1:13 (15 April 2013)

Abstract | Full text | PDF |  Editor’s summary

People with anorexia nervosa may have fundamental problems with thinking style and emotional capacity that predispose and maintain the illness.

17.

Study protocol   Open Access

Study protocol for iQuit in Practice: a randomised controlled trial to assess the feasibility, acceptability and effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care

Stephen Sutton, Susan Smith, James Jamison, Sue Boase, Dan Mason, A Toby Prevost, James Brimicombe, Melanie Sloan, Hazel Gilbert, Felix Naughton BMC Public Health 2013, 13:324 (10 April 2013)

Abstract | Full text | PDF | PubMed

18.

Short report   Open Access

Array CGH as a first line diagnostic test in place of karyotyping for postnatal referrals - results from four years’ clinical application for over 8,700 patients

Joo Wook Ahn, Susan Bint, Anne Bergbaum, Kathy Mann, Richard P Hall, Caroline Mackie Ogilvie Molecular Cytogenetics 2013, 6:16 (5 April 2013)

Abstract | Full text | PDF | PubMed

19.

Research article   Open Access Highly Accessed

The relationship between DXA-based and anthropometric measures of visceral fat and morbidity in women

Kenan Direk, Marina Cecelja, William Astle, Phil Chowienczyk, Tim D Spector, Mario Falchi, Toby Andrew BMC Cardiovascular Disorders 2013, 13:25 (3 April 2013)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

A comparison between the 2010 and 2005 basic life support guidelines during simulated hypogravity and microgravity

Thais Russomano, Justin H Baers, Rochelle Velho, Ricardo B Cardoso, Alexandra Ashcroft, Lucas Rehnberg, Rodrigo D Gehrke, Mariana K P Dias, Rafael R Baptista Extreme Physiology & Medicine 2013, 2:11 (1 April 2013)

Abstract | Full text | PDF

21.

Review   Open Access

Patent foramen ovale and scuba diving: a practical guide for physicians on when to refer for screening

Oliver Sykes, James E Clark Extreme Physiology & Medicine 2013, 2:10 (1 April 2013)

Abstract | Full text | PDF

22.

Research article   Open Access

The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling

Roman H Khonsari, Maisa Seppala, Alan Pradel, Hugo Dutel, Gaël Clément, Oleg Lebedev, Sarah Ghafoor, Michaela Rothova, Abigael Tucker, John G Maisey, Chen-Ming Fan, Maiko Kawasaki, Atsushi Ohazama, Paul Tafforeau, Brunella Franco, Jill Helms, Courtney J Haycraft, Albert David, Philippe Janvier, Martyn T Cobourne, Paul T Sharpe BMC Biology 2013, 11:27 (28 March 2013)

Abstract | Full text | PDF | PubMed

23.

Research   Open Access Highly Accessed

Evaluation of Greek psychiatric reforms: methodological issues

Evangelia Loukidou, Anastasios Mastroyannakis, Tracey Power, Graham Thornicroft, Tom Craig, Nick Bouras International Journal of Mental Health Systems 2013, 7:11 (28 March 2013)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

The association between social relationships and self-harm: a case–control study in Taiwan

Chia-Yi Wu, Chin-Kuo Chang, Hui-Chun Huang, Shen-Ing Liu, Robert Stewart BMC Psychiatry 2013, 13:101 (26 March 2013)

Abstract | Full text | PDF | PubMed

25.

Research article   Open Access Highly Accessed

Developmental time rather than local environment regulates the schedule of epithelial polarization in the zebrafish neural rod

Gemma C Girdler, Claudio Araya, Xiaoyun Ren, Jonathan DW Clarke Neural Development 2013, 8:5 (24 March 2013)

Abstract | Full text | PDF | PubMed

26.

Research article   Open Access

The role of nicotine replacement therapy for temporary abstinence in the home to protect children from environmental tobacco smoke exposure: a qualitative study with disadvantaged smokers

Olesya Atkinson, Tim Coleman, Ann McNeill, Sarah Lewis, Laura L Jones BMC Public Health 2013, 13:262 (22 March 2013)

Abstract | Full text | PDF | PubMed

27.

Review   Open Access Highly Accessed

Applying systems biology methods to the study of human physiology in extreme environments

Lindsay M Edwards, Ines Thiele Extreme Physiology & Medicine 2013, 2:8 (22 March 2013)

Abstract | Full text | PDF |  Editor’s summary

Edwards and Thiele define Systems Biology as "an iterative process of computational model-building and experimental model-revision with the aim of understanding or simulating complex biological systems". Further, they highlight the limited number of physiologically relevant perturbations that are ethically acceptable in humans and highlight the value of environmental and exertional stressors in this context.

28.

Research article   Open Access

Patients’ perceptions of depression and coronary heart disease: a qualitative UPBEAT-UK study

Rosemary L Simmonds, Andre Tylee, Paul Walters, Diana Rose BMC Family Practice 2013, 14:38 (19 March 2013)

Abstract | Full text | PDF | PubMed

29.

Study protocol   Open Access

Financial incentives for smoking cessation in pregnancy: protocol for a single arm intervention study

Theresa M Marteau, Josephine Thorne, Paul Aveyard, Julie Hirst, Rachel Sokal BMC Pregnancy and Childbirth 2013, 13:66 (15 March 2013)

Abstract | Full text | PDF | PubMed

30.

Correspondence   Open Access

Ethical challenges in mental health research among internally displaced people: ethical theory and research implementation

Chesmal Siriwardhana, Anushka Adikari, Kaushalya Jayaweera, Athula Sumathipala BMC Medical Ethics 2013, 14:13 (12 March 2013)

Abstract | Full text | PDF | PubMed

31.

Research article   Open Access

‘Burden to others’ as a public concern in advanced cancer: a comparative survey in seven European countries

Claudia Bausewein, Natalia Calanzani, Barbara A Daveson, Steffen T Simon, Pedro L Ferreira, Irene J Higginson, Dorothee Bechinger-English, Luc Deliens, Marjolein Gysels, Franco Toscani, Lucas Ceulemans, Richard Harding, Barbara Gomes, BMC Cancer 2013, 13:105 (8 March 2013)

Abstract | Full text | PDF | PubMed

32.

Research article   Open Access

Symptoms of common mental disorder and cognitive associations with seropositivity among a cohort of people coming for testing for HIV/AIDS in Goa, India: a cross-sectional survey

Rosie Mayston, Vikram Patel, Melanie Abas, Priya Korgaonkar, Ramesh Paranjape, Savio Rodrigues, Martin Prince BMC Public Health 2013, 13:204 (7 March 2013)

Abstract | Full text | PDF | PubMed

33.

Research   Open Access

Ethnic variation in the activity of lipid desaturases and their relationships with cardiovascular risk factors in control women and an at-risk group with previous gestational diabetes mellitus: a cross-sectional study

Robert G Gray, Eleni Kousta, Mark I McCarthy, Ian F Godsland, Soundarajan Venkatesan, Victor Anyaoku, Desmond G Johnston Lipids in Health and Disease 2013, 12:25 (6 March 2013)

Abstract | Full text | PDF | PubMed

34.

Commentary   Open Access

Neural connectivity abnormalities in autism: Insights from the tuberous sclerosis model

Charlotte Tye, Patrick Bolton BMC Medicine 2013, 11:55 (27 February 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Charlotte Tye and Patrick Bolton comment on a study showing that neural networks differ in tuberous sclerosis patients with and without autism spectrum disorder (ASD), and describe how the results support the theory of altered neural circuitry in ASD.

35.

Research   Open Access

Impact of malocclusion on oral health related quality of life in young people

Yaghma Masood, Mohd Masood, Nurul Nadiah Binti Zainul, Nurhuda Binti Abdul Alim Araby, Saba Fouad Hussain, Tim Newton Health and Quality of Life Outcomes 2013, 11:25 (26 February 2013)

Abstract | Full text | PDF | PubMed

36.

Short report   Open Access Highly Accessed

Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection

Caroline Goujon, Torsten Schaller, Rui Pedro Galão, Sarah M Amie, Baek Kim, Kevin Olivieri, Stuart JD Neil, Michael H Malim Retrovirology 2013, 10:23 (25 February 2013)

Abstract | Full text | PDF | PubMed

37.

Research   Open Access

Management of adult attention deficit hyperactivity disorder in UK primary care: a survey of general practitioners

Suzanne McCarthy, Lynda Wilton, Macey Murray, Paul Hodgkins, Philip Asherson, Ian CK Wong Health and Quality of Life Outcomes 2013, 11:22 (22 February 2013)

Abstract | Full text | PDF | PubMed

38.

Study protocol   Open Access

Effectiveness of alcohol brief intervention delivered by community pharmacists: study protocol of a two-arm randomised controlled trial

Ranjita Dhital, Ian Norman, Cate Whittlesea, Jim McCambridge BMC Public Health 2013, 13:152 (18 February 2013)

Abstract | Full text | PDF | PubMed

39.

Correspondence   Open Access Highly Accessed

Occupational issues of adults with ADHD

Marios Adamou, Muhammad Arif, Philip Asherson, Tar-Ching Aw, Blanca Bolea, David Coghill, Gísli Guðjónsson, Anne Halmøy, Paul Hodgkins, Ulrich Müller, Mark Pitts, Anna Trakoli, Nerys Williams, Susan Young BMC Psychiatry 2013, 13:59 (17 February 2013)

Abstract | Full text | PDF | PubMed

40.

Review   Subscription Highly Accessed

Genes and epigenetic processes as prospective pain targets

Megan Crow, Franziska Denk, Stephen B McMahon Genome Medicine 2013, 5:12 (15 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Stephen McMahon and colleagues review treatments for pain relief, which are often inadequate, and discuss how understanding of the genomic and epigenomic mechanisms might lead to improved drugs.

41.

Research article   Open Access Highly Accessed

Heterogeneity and changes in preferences for dying at home: a systematic review

Barbara Gomes, Natalia Calanzani, Marjolein Gysels, Sue Hall, Irene J Higginson BMC Palliative Care 2013, 12:7 (15 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Evidence from the literature suggests that as illness progresses, most people prefer to die at home and most do not change their preferred location to die, however, there is a significant minority whose views must be taken into account.

42.

Review   Open Access

Therapygenetics: Using genetic markers to predict response to psychological treatment for mood and anxiety disorders

Kathryn J Lester, Thalia C Eley Biology of Mood & Anxiety Disorders 2013, 3:4 (7 February 2013)

Abstract | Full text | PDF | PubMed

43.

Review   Open Access

Depression pathogenesis and treatment: what can we learn from blood mRNA expression?

Nilay Hepgul, Annamaria Cattaneo, Patricia A Zunszain, Carmine M Pariante BMC Medicine 2013, 11:28 (5 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Carmine Pariante and colleagues review the altered pattern of peripheral gene expression in patients with major depressive disorder, and comment on the clinical applicability of potential biomarkers to measure these reversible changes in patients.

44.

Research article   Open Access

Development and psychometric properties of a five-language multiperspective instrument to assess clinical decision making style in the treatment of people with severe mental illness (CDMS)

Bernd Puschner, Petra Neumann, Harriet Jordan, Mike Slade, Andrea Fiorillo, Domenico Giacco, Anikó Égerházi, Tibor Ivánka, Malene Krogsgaard Bording, Helle Østermark Sørensen, Arlette Bär, Wolfram Kawohl, Sabine Loos, BMC Psychiatry 2013, 13:48 (4 February 2013)

Abstract | Full text | PDF | PubMed

45.

Research   Open Access

Exploring the perspectives and experiences of health workers at primary health facilities in Kenya following training

Rachel Jenkins, Caleb Othieno, Stephen Okeyo, Julyan Aruwa, Jan Wallcraft, Ben Jenkins International Journal of Mental Health Systems 2013, 7:6 (4 February 2013)

Abstract | Full text | PDF | PubMed

46.

Research   Open Access

Iron status is inversely associated with dietary iron intakes in patients with inactive or mildly active inflammatory bowel disease

Jonathan J Powell, William B Cook, Mark Chatfield, Carol Hutchinson, Dora IA Pereira, Miranda CE Lomer Nutrition & Metabolism 2013, 10:18 (1 February 2013)

Abstract | Full text | PDF | PubMed

47.

Short Report   Open Access

Investigation of the ZNF804A gene polymorphism with genetic risk for bipolar disorder in attention deficit hyperactivity disorder

Xiaohui Xu, Gerome Breen, Lucy Luo, Bo Sun, Chih-Ken Chen, Ursula M Paredes, Yu-Shu Huang, Yu-Yu Wu, Philip Asherson BMC Research Notes 2013, 6:29 (26 January 2013)

Abstract | Full text | PDF | PubMed

48.

Research highlight   Subscription

Thick and thin fingers point out Turing waves

Andrew D Economou, Jeremy BA Green Genome Biology 2013, 14:101 (24 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A Research Highlight on the mystery of finger formation: how Alan Turing's proposed reaction-diffusion mechanism underlies digit development

49.

Study protocol   Open Access Highly Accessed

Implementing training and support, financial reimbursement, and referral to an internet-based brief advice program to improve the early identification of hazardous and harmful alcohol consumption in primary care (ODHIN): study protocol for a cluster randomized factorial trial

Myrna N Keurhorst, Peter Anderson, Fredrik Spak, Preben Bendtsen, Lidia Segura, Joan Colom, Jillian Reynolds, Colin Drummond, Paolo Deluca, Ben van Steenkiste, Artur Mierzecki, Karolina Kłoda, Paul Wallace, Dorothy Newbury-Birch, Eileen Kaner, Toni Gual, Miranda GH Laurant Implementation Science 2013, 8:11 (24 January 2013)

Abstract | Full text | PDF | PubMed

50.

Research article   Open Access

Integrating mobile-phone based assessment for psychosis into people’s everyday lives and clinical care: a qualitative study

Jasper E Palmier-Claus, Anne Rogers, John Ainsworth, Matt Machin, Christine Barrowclough, Louise Laverty, Emma Barkus, Shitij Kapur, Til Wykes, Shôn W Lewis BMC Psychiatry 2013, 13:34 (23 January 2013)

Abstract | Full text | PDF | PubMed

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