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76.

Commentary   Open Access

OMERACT: An international initiative to improve outcome measurement in rheumatology

Peter Tugwell, Maarten Boers, Peter Brooks, Lee Simon, Vibeke Strand, Leanne Idzerda Trials 2007, 8:38 (26 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

77.

Research   Open Access

Multi-Country analysis of palm oil consumption and cardiovascular disease mortality for countries at different stages of economic development: 1980-1997

Brian K Chen, Benjamin Seligman, John W Farquhar, Jeremy D Goldhaber-Fiebert Globalization and Health 2011, 7:45 (16 December 2011)

Abstract | Full text | PDF | PubMed

78.

Research article   Open Access Highly Accessed

Genome reannotation of the lizard Anolis carolinensis based on 14 adult and embryonic deep transcriptomes

Walter L Eckalbar, Elizabeth D Hutchins, Glenn J Markov, April N Allen, Jason J Corneveaux, Kerstin Lindblad-Toh, Federica Di Palma, Jessica Alföldi, Matthew J Huentelman, Kenro Kusumi BMC Genomics 2013, 14:49 (23 January 2013)

Abstract | Full text | PDF | PubMed

79.

Research article   Open Access Highly Accessed

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies

Chih Liu, Stephanie Tangsombatvisit, Jacob M Rosenberg, Gil Mandelbaum, Emily C Gillespie, Or P Gozani, Ash A Alizadeh, Paul J Utz Arthritis Research & Therapy 2012, 14:R25 (2 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

80.

Methodology article   Open Access Highly Accessed

Digital PCR provides sensitive and absolute calibration for high throughput sequencing

Richard A White, Paul C Blainey, H Christina Fan, Stephen R Quake BMC Genomics 2009, 10:116 (19 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

81.

Review   Open Access

Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

Jie Hu, Zhonghua Zhang, Wen-Jun Shen, Salman Azhar Nutrition & Metabolism 2010, 7:47 (1 June 2010)

Abstract | Full text | PDF | PubMed

82.

Research   Open Access Highly Accessed

A Meta-analysis of the effects of Exercise Training on Left Ventricular Remodeling Following Myocardial Infarction: Start early and go longer for greatest exercise benefits on remodeling

Mark Haykowsky, Jessica Scott, Ben Esch, Don Schopflocher, Jonathan Myers, Ian Paterson, Darren Warburton, Lee Jones, Alexander M Clark Trials 2011, 12:92 (4 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

Method   Open Access

A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis

Simon E Alfred, Anuradha Surendra, Chris Le, Ken Lin, Alexander Mok, Iain M Wallace, Michael Proctor, Malene L Urbanus, Guri Giaever, Corey Nislow Genome Biology 2012, 13:R105 (18 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An automated small molecule screening method for Chlamydomonas reinhardtii, and its application to identify bioactive compounds for agriculture, biofuels and therapeutics

84.

Proceedings   Open Access Highly Accessed

The Translational Medicine Ontology and Knowledge Base: driving personalized medicine by bridging the gap between bench and bedside

Joanne S Luciano, Bosse Andersson, Colin Batchelor, Olivier Bodenreider, Tim Clark, Christine K Denney, Christopher Domarew, Thomas Gambet, Lee Harland, Anja Jentzsch, Vipul Kashyap, Peter Kos, Julia Kozlovsky, Timothy Lebo, Scott M Marshall, James P McCusker, Deborah L McGuinness, Chimezie Ogbuji, Elgar Pichler, Robert L Powers, Eric Prud’hommeaux, Matthias Samwald, Lynn Schriml, Peter J Tonellato, Patricia L Whetzel, Jun Zhao, Susie Stephens, Michel Dumontier Journal of Biomedical Semantics 2011, 2(Suppl 2):S1 (17 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

85.

Review   Open Access

Mental health issues in unaccompanied refugee minors

Julia Huemer, Niranjan S Karnik, Sabine Voelkl-Kernstock, Elisabeth Granditsch, Kanita Dervic, Max H Friedrich, Hans Steiner Child and Adolescent Psychiatry and Mental Health 2009, 3:13 (2 April 2009)

Abstract | Full text | PDF | PubMed

86.

Methodology article   Open Access Highly Accessed

STOP using just GO: a multi-ontology hypothesis generation tool for high throughput experimentation

Tobias Wittkop, Emily TerAvest, Uday S Evani, K Fleisch, Ari E Berman, Corey Powell, Nigam H Shah, Sean D Mooney BMC Bioinformatics 2013, 14:53 (14 February 2013)

Abstract | Full text | PDF | PubMed

87.

Correspondence   Open Access Highly Accessed

Translational bioinformatics in the cloud: an affordable alternative

Joel T Dudley, Yannick Pouliot, Rong Chen, Alexander A Morgan, Atul J Butte Genome Medicine 2010, 2:51 (6 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Cloud-based analysis offers a valid alternative both in terms of performance and cost to local computational clusters for the integration and analysis of large-scale genomic datasets relevant for translational research.

88.

Research   Open Access Highly Accessed

Human umbilical cord blood-derived mononuclear cell transplantation: case series of 30 subjects with Hereditary Ataxia

Wan-Zhang Yang, Yun Zhang, Fang Wu, Min Zhang, SC Cho, Chun-Zhen Li, Shao-Hui Li, Guo-Jian Shu, You-Xiang Sheng, Ning Zhao, Ying Tang, Shu Jiang, Shan Jiang, Matthew Gandjian, Thomas E Ichim, Xiang Hu Journal of Translational Medicine 2011, 9:65 (16 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

89.

Research article   Open Access Highly Accessed

Development of an EGFRvIII specific recombinant antibody

Puja Gupta, Shuang-Yin Han, Marina Holgado-Madruga, Siddhartha S Mitra, Gordon Li, Ryan T Nitta, Albert J Wong BMC Biotechnology 2010, 10:72 (7 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

90.

Method   Open Access Highly Accessed

Modeling non-uniformity in short-read rates in RNA-Seq data

Jun Li, Hui Jiang, Wing Wong Genome Biology 2010, 11:R50 (11 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Methods for modeling read counts from short read RNA-seq data.

91.

Research article   Open Access Highly Accessed

Breast cancer risk assessment across the risk continuum: genetic and nongenetic risk factors contributing to differential model performance

Anne S Quante, Alice S Whittemore, Tom Shriver, Konstantin Strauch, Mary B Terry Breast Cancer Research 2012, 14:R144 (5 November 2012)

Abstract | Full text | PDF | PubMed

92.

Research   Open Access Highly Accessed

Measurement of a model of implementation for health care: toward a testable theory

Joan M Cook, Casey O’Donnell, Stephanie Dinnen, James C Coyne, Josef I Ruzek, Paula P Schnurr Implementation Science 2012, 7:59 (3 July 2012)

Abstract | Full text | PDF | PubMed

93.

Letter   Free Highly Accessed

Potential for overuse of corticosteroids and vasopressin in septic shock

Joe L Hsu, Vincent Liu, Andrew J Patterson, Greg S Martin, Mark R Nicolls, James A Russell Critical Care 2012, 16:447 (6 September 2012)

Abstract | Full text | PDF | PubMed

94.

Research article   Open Access Highly Accessed

Cell-type specific gene expression profiles of leukocytes in human peripheral blood

Chana Palmer, Maximilian Diehn, Ash A Alizadeh, Patrick O Brown BMC Genomics 2006, 7:115 (16 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

95.

Research article   Open Access Highly Accessed

Occurrence of breast cancer subtypes in adolescent and young adult women

Theresa HM Keegan, Mindy C DeRouen, David J Press, Allison W Kurian, Christina A Clarke Breast Cancer Research 2012, 14:R55 (27 March 2012)

Abstract | Full text | PDF | PubMed

96.

Research article   Open Access Highly Accessed

The coming of the Greeks to Provence and Corsica: Y-chromosome models of archaic Greek colonization of the western Mediterranean

Roy J King, Julie Di Cristofaro, Anastasia Kouvatsi, Costas Triantaphyllidis, Walter Scheidel, Natalie M Myres, Alice A Lin, Alexandre Eissautier, Michael Mitchell, Didier Binder, Ornella Semino, Andrea Novelletto, Peter A Underhill, Jacques Chiaroni BMC Evolutionary Biology 2011, 11:69 (14 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

97.

Research   Open Access

Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs

Michelle Kudron, Wei Niu, Zhi Lu, Guilin Wang, Mark Gerstein, Michael Snyder, Valerie Reinke Genome Biology 2013, 14:R5 (23 January 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

The tissue specificity of Rb/E2F binding profiles enables the promotion of both somatic and germline transcriptional programs

98.

Research   Open Access Highly Accessed

Neural temporal dynamics of stress in comorbid major depressive disorder and social anxiety disorder

Christian E Waugh, J Hamilton, Michael C Chen, Jutta Joormann, Ian H Gotlib Biology of Mood & Anxiety Disorders 2012, 2:11 (22 June 2012)

Abstract | Full text | PDF | PubMed

99.

Research   Open Access Highly Accessed

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways

Rachid Kacimi, Rona G Giffard, Midori A Yenari Journal of Inflammation 2011, 8:7 (7 March 2011)

Abstract | Full text | PDF | PubMed

100.

Methodology article   Open Access Highly Accessed

Targeted sequencing library preparation by genomic DNA circularization

Samuel Myllykangas, Georges Natsoulis, John M Bell, Hanlee P Ji BMC Biotechnology 2011, 11:122 (14 December 2011)

Abstract | Full text | PDF | PubMed

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