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326.

Research article   Open Access Highly Accessed

A compact VEGF signature associated with distant metastases and poor outcomes

Zhiyuan Hu, Cheng Fan, Chad Livasy, Xiaping He, Daniel S Oh, Matthew G Ewend, Lisa A Carey, Subbaya Subramanian, Robert West, Francis Ikpatt, Olufunmilayo I Olopade, Matt van de Rijn, Charles M Perou BMC Medicine 2009, 7:9 (16 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Expression of the 13-gene VEGF (vascular endothelial growth factor) profile occurs in distant cancer metastases and is predictive of poor outcome, but may help to target anti-angiogenesis therapies.

327.

Research   Open Access Highly Accessed

Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells

Wei Wei, Mei-Sze Chua, Susan Grepper, Samuel K So Molecular Cancer 2009, 8:76 (24 September 2009)

Abstract | Full text | PDF | PubMed

328.

Research   Open Access

In vivo USPIO magnetic resonance imaging shows that minocycline mitigates macrophage recruitment to a peripheral nerve injury

Pejman Ghanouni, Deepak Behera, Jin Xie, Xiaoyuan Chen, Michael Moseley, Sandip Biswal Molecular Pain 2012, 8:49 (28 June 2012)

Abstract | Full text | PDF | PubMed

329.

Research article   Open Access

Different selective pressures lead to different genomic outcomes as newly-formed hybrid yeasts evolve

Jeff S Piotrowski, Saisubramanian Nagarajan, Evgueny Kroll, Alison Stanbery, Kami E Chiotti, Arthur L Kruckeberg, Barbara Dunn, Gavin Sherlock, Frank Rosenzweig BMC Evolutionary Biology 2012, 12:46 (2 April 2012)

Abstract | Full text | PDF | PubMed

330.

Research   Open Access

Genome-wide analysis of mRNA lengths in Saccharomyces cerevisiae

Evan H Hurowitz, Patrick O Brown Genome Biology 2003, 5:R2 (22 December 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

A novel 'Virtual Northern' method provides a practical and efficient method for genome-scale analysis of mRNA transcript lengths. A study in Saccharomyces cerevisiae has revealed that approximately 12-15% of the yeast genome is represented in untranslated sequences of mRNAs.

331.

Technical advance   Open Access Highly Accessed

Myocardial strains from 3D displacement encoded magnetic resonance imaging

Katarina Kindberg, Henrik Haraldsson, Andreas Sigfridsson, Jan Engvall, Neil B Ingels, Tino Ebbers, Matts Karlsson BMC Medical Imaging 2012, 12:9 (25 April 2012)

Abstract | Full text | PDF | PubMed

332.

Research   Open Access

Interim-treatment quantitative PET parameters predict progression and death among patients with hodgkin's disease

Diane Tseng, Leelanand P Rachakonda, Zheng Su, Ranjana Advani, Sandra Horning, Richard T Hoppe, Andrew Quon, Edward E Graves, Billy W Loo, Phuoc T Tran Radiation Oncology 2012, 7:5 (19 January 2012)

Abstract | Full text | PDF | PubMed

333.

Case report   Open Access

Large B- Cell lymphoma presenting as acute abdominal pain and spontaneous splenic rupture; A case report and review of relevant literature

Saptarshi Biswas, Judith Keddington, James McClanathan World Journal of Emergency Surgery 2006, 1:35 (28 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

334.

Research   Open Access

Differential regulation of PGC-1α expression in rat liver and skeletal muscle in response to voluntary running

Renata Matiello, Rosa T Fukui, Maria ER Silva, Dalva M Rocha, Bernardo L Wajchenberg, Salman Azhar, Rosa F Santos Nutrition & Metabolism 2010, 7:36 (30 April 2010)

Abstract | Full text | PDF | PubMed

335.

Original investigation   Open Access Highly Accessed

Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance

Urszula Razny, Beata Kiec-Wilk, Lukasz Wator, Anna Polus, Grzegorz Dyduch, Bogdan Solnica, Maciej Malecki, Romana Tomaszewska, John P Cooke, Aldona Dembinska-Kiec Cardiovascular Diabetology 2011, 10:68 (22 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

336.

Method   Open Access

Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays

Melissa H Pespeni, Thomas A Oliver, Mollie K Manier, Stephen R Palumbi Genome Biology 2010, 11:R44 (19 April 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A method for the simultaneous identification of polymorphic loci and the quantitative genotyping of thousands of loci in individuals is presented.

337.

Research article   Open Access

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Andreas M Grabrucker, Michael J Schmeisser, Patrick T Udvardi, Magali Arons, Michael Schoen, Nathaniel S Woodling, Katrin I Andreasson, Patrick R Hof, Joseph D Buxbaum, Craig C Garner, Tobias M Boeckers Molecular Neurodegeneration 2011, 6:65 (22 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

338.

Research article   Open Access

Predicting environmental chemical factors associated with disease-related gene expression data

Chirag J Patel, Atul J Butte BMC Medical Genomics 2010, 3:17 (6 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

339.

Research   Open Access

Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode

Shai S Shen-Orr, Yitzhak Pilpel, Craig P Hunter Genome Biology 2010, 11:R58 (1 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Analysis of maternal and zygotic transcripts reveals regulatory differences between mammals and egg- laying animals.

340.

Research   Open Access

Balance billing: the patients' perspective

Mathias Kifmann, Florian Scheuer Health Economics Review 2011, 1:14 (17 September 2011)

Abstract | Full text | PDF

341.

Short communication   Open Access Highly Accessed

A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice

Alice C Fan, Marianna M Goldrick, Jennifer Ho, Yu Liang, Pavan Bachireddy, Dean W Felsher Molecular Cancer 2008, 7:74 (30 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

342.

Commentary   Open Access

MIAME/Plant – adding value to plant microarrray experiments

Philip Zimmermann, Beatrice Schildknecht, David Craigon, Margarita Garcia-Hernandez, Wilhelm Gruissem, Sean May, Gaurab Mukherjee, Helen Parkinson, Seung Rhee, Ulrich Wagner, Lars Hennig Plant Methods 2006, 2:1 (9 January 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

343.

Question & Answer   Free Highly Accessed

Q&A: Systems biology

James E Ferrell Journal of Biology 2009, 8:2 (26 January 2009)

Full text | PDF | PubMed | Cited on BioMed Central

344.

Debate   Open Access

What is the potential of oligodendrocyte progenitor cells to successfully treat human spinal cord injury?

Robert A Watson, Trevor M Yeung BMC Neurology 2011, 11:113 (23 September 2011)

Abstract | Full text | PDF | PubMed

345.

Primary research   Open Access Highly Accessed

Cognitive status and behavioral problems in older hospitalized patients

Ruth O'Hara, Martin S Mumenthaler, Helen Davies, Erin L Cassidy, Martha Buffum, Sarojini Namburi, Roxanne Shakoori, Claire E Danielsen, Patricia Tsui, Art Noda, Helena C Kraemer, Javaid I Sheikh Annals of General Hospital Psychiatry 2002, 1:1 (27 September 2002)

Abstract | Full text | PDF | PubMed

346.

Research   Open Access Highly Accessed

Identification of potential therapeutic targets in human head & neck squamous cell carcinoma

Jing Han, Mitomu Kioi, Wei-Sing Chu, Jan L Kasperbauer, Scott E Strome, Raj K Puri Head & Neck Oncology 2009, 1:27 (14 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Five genes and their products, shown to be upregulated in human head and neck squamous cell carcinomas, have been characterised and may serve as potential new diagnostic markers and therapeutic targets.

347.

Research article   Open Access Highly Accessed

Combined optical trapping and single-molecule fluorescence

Matthew J Lang, Polly M Fordyce, Steven M Block Journal of Biology 2003, 2:6 (24 February 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

348.

Proceedings   Open Access

Combining joint models for biomedical event extraction

David McClosky, Sebastian Riedel, Mihai Surdeanu, Andrew McCallum, Christopher D Manning BMC Bioinformatics 2012, 13(Suppl 11):S9 (26 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

349.

Research   Open Access Highly Accessed

The complete genome of klassevirus – a novel picornavirus in pediatric stool

Alexander L Greninger, Charles Runckel, Charles Y Chiu, Thomas Haggerty, Julie Parsonnet, Donald Ganem, Joseph L DeRisi Virology Journal 2009, 6:82 (18 June 2009)

Abstract | Full text | PDF | PubMed

350.

Research article   Open Access

A diagnostic algorithm combining clinical and molecular data distinguishes Kawasaki disease from other febrile illnesses

Xuefeng B Ling, Kenneth Lau, John T Kanegaye , Zheng Pan, Sihua Peng, Jun Ji, Gigi Liu, Yuichiro Sato, Tom TS Yu, John C Whitin, James Schilling, Jane C Burns, Harvey J Cohen BMC Medicine 2011, 9:130 (6 December 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Diagnosis of Kawasaki disease, an acute vasculitis of infants and young children characterized by an array of symptoms that can mimic other benign conditions, may be easier with a new multi-step algorithm

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