151.
An in vitro -identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo
Lia
E
Gracey,
Zhi-Ying
Chen,
Jay
M
Maniar,
Anton
Valouev,
Arend
Sidow,
Mark
A
Kay,
Andrew
Z
Fire
Epigenetics & Chromatin 2010, 3 :13 (1 July 2010)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The introduction of a synthetic high-affinity nucleosome-positioning signal into a DNA plasmid vector in mice results in the strong yet transient positioning of nucleosomes in vivo.
152.
Is breast cancer a part of Lynch syndrome?
James
M
Ford
Breast Cancer Research 2012, 14 :110 (22 August 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
153.
Occurrence of breast cancer subtypes in adolescent and young adult women
Theresa
HM
Keegan,
Mindy
C
DeRouen,
David
J
Press,
Allison
W
Kurian,
Christina
A
Clarke
Breast Cancer Research 2012, 14 :R55 (27 March 2012)
Abstract | Full text | PDF | PubMed
154.
STOP using just GO: a multi-ontology hypothesis generation tool for high throughput experimentation
Tobias
Wittkop,
Emily
TerAvest,
Uday
S
Evani,
K
Fleisch,
Ari
E
Berman,
Corey
Powell,
Nigam
H
Shah,
Sean
D
Mooney
BMC Bioinformatics 2013, 14 :53 (14 February 2013)
Abstract | Full text | PDF | PubMed
155.
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
Xiaoyan
Zhao,
Nwora
Okeke,
Orr
Sharpe,
Franak
M
Batliwalla,
Annette
T
Lee,
Peggy
P
Ho,
Beren
H
Tomooka,
Peter
K
Gregersen,
William
H
Robinson
Arthritis Research & Therapy 2008, 10 :R94 (18 August 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
156.
Inflammation signals airway smooth muscle cell proliferation in asthma pathogenesis
Mohammad Afzal
Khan
Multidisciplinary Respiratory Medicine 2013, 8 :11 (6 February 2013)
Abstract | Full text | PDF | PubMed
157.
Correction: Mechanisms of stomatal development: an evolutionary view
Anne
Vatén,
Dominique
C
Bergmann
EvoDevo 2013, 4 :11 (4 April 2013)
Abstract | Full text | PDF | PubMed
158.
Africa and the global carbon cycle
Christopher
A
Williams,
Niall
P
Hanan,
Jason
C
Neff,
Robert
J
Scholes,
Joseph
A
Berry,
A Scott
Denning,
David
F
Baker
Carbon Balance and Management 2007, 2 :3 (7 March 2007)
Abstract | Full text | PDF | PubMed
159.
Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report
Steven
M
Chan,
Tracy
George,
Athena
M
Cherry,
Bruno
C
Medeiros
Cases Journal 2009, 2 :121 (4 February 2009)
Abstract | Full text | PDF | PubMed
160.
Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action
Maureen
E
Hillenmeyer,
Elke
Ericson,
Ronald
W
Davis,
Corey
Nislow,
Daphne
Koller,
Guri
Giaever
Genome Biology 2010, 11 :R30 (12 March 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The relationship between co-fitness and co-inhibition of genes in chemicogenomic yeast screens provides insights into gene function and drug target prediction.
161.
Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers
Robert
C
Spitale,
Michelle
Y
Cheng,
Kimberly
A
Chun,
Emily
S
Gorell,
Claudia
A
Munoz,
Dale
G
Kern,
Steve
M
Wood,
Helen
E
Knaggs,
Jacob
Wulff,
Kirk
D
Beebe,
Anne Lynn
S
Chang
Genome Medicine 2012, 4 :14 (23 February 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A study of the effects of antioxidant dietary supplementation
on the metabolomes and the skin of smokers and non-smokers suggests that antioxidants may be of more benefit to smokers.
162.
Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey
Eleni
Linos,
David
Fiorentino,
Bharathi
Lingala,
Eswar
Krishnan,
Lorinda
Chung
Arthritis Research & Therapy 2013, 15 :R7 (8 January 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Patients suffering from both dermatomyositis and an atherosclerotic cardiovascular disease (CVD) are twice as likely to die during inpatient stay compared to controls with CVD, and dermatomyositis patients without CVD.
163.
Text mining for biology - the way forward: opinions from leading scientists
Russ
B
Altman,
Casey
M
Bergman,
Judith
Blake,
Christian
Blaschke,
Aaron
Cohen,
Frank
Gannon,
Les
Grivell,
Udo
Hahn,
William
Hersh,
Lynette
Hirschman,
Lars
Jensen,
Martin
Krallinger,
Barend
Mons,
Seán
I
O'Donoghue,
Manuel
C
Peitsch,
Dietrich
Rebholz-Schuhmann,
Hagit
Shatkay,
Alfonso
Valencia
Genome Biology 2008, 9 (Suppl 2):S7 (1 September 2008)
Abstract | Full text | PDF
164.
Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
Basil
Honegger,
Milos
Galic,
Katja
Köhler,
Franz
Wittwer,
Walter
Brogiolo,
Ernst
Hafen,
Hugo
Stocker
Journal of Biology 2008, 7 :10 (15 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The first functional insulin-binding protein identified in invertebrates, Imp-L2, controls Drosophila body size by regulating insulin-mediated growth and is essential for larval survival and dampening insulin signaling under starvation conditions.
165.
Inhaled Nitric Oxide in preterm infants: a systematic review and individual patient data meta-analysis
Lisa
M
Askie,
Roberta
A
Ballard,
Gary
Cutter,
Carlo
Dani,
Diana
Elbourne,
David
Field,
Jean-Michel
Hascoet,
Anna
Hibbs,
John
P
Kinsella,
Jean-Christophe
Mercier,
Wade
Rich,
Michael
D
Schreiber,
Pimol
Srisuparp,
Nim
V
Subhedar,
Krisa
P
Van Meurs,
Merryn
Voysey,
Keith
Barrington,
Richard
A
Ehrenkranz,
Neil
Finer,
BMC Pediatrics 2010, 10 :15 (23 March 2010)
Abstract | Full text | PDF | PubMed
166.
A Meta-analysis of the effects of Exercise Training on Left Ventricular Remodeling Following Myocardial Infarction: Start early and go longer for greatest exercise benefits on remodeling
Mark
Haykowsky,
Jessica
Scott,
Ben
Esch,
Don
Schopflocher,
Jonathan
Myers,
Ian
Paterson,
Darren
Warburton,
Lee
Jones,
Alexander
M
Clark
Trials 2011, 12 :92 (4 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
167.
Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development
James
F
Fries,
Eswar
Krishnan
Arthritis Res Ther 2004, 6 :R250-R255 (18 March 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The 'uncertainty principle' states that randomised controlled trials are only ethical if true uncertainty exists about which treatment is likely to be superior. Is this principle being violated in industry-sponsored trials?
168.
Tools for loading MEDLINE into a local relational database
Diane
E
Oliver,
Gaurav
Bhalotia,
Ariel
S
Schwartz,
Russ
B
Altman,
Marti
A
Hearst
BMC Bioinformatics 2004, 5 :146 (7 October 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
169.
World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malaria
Christopher
V
Plowe,
Cally
Roper,
John
W
Barnwell,
Christian
T
Happi,
Hema
H
Joshi,
Wilfred
Mbacham,
Steven
R
Meshnick,
Kefas
Mugittu,
Inbarani
Naidoo,
Ric
N
Price,
Robert
W
Shafer,
Carol
H
Sibley,
Colin
J
Sutherland,
Peter
A
Zimmerman,
Philip
J
Rosenthal
Malaria Journal 2007, 6 :121 (6 September 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
The review describes previous successes on using molecular markers of drug resistance and lessons learned. A standardized global database of molecular markers of drug resistance linking up with databases containing in vivo efficacy trial results, in vitro and pharmacokinetic studies could form an essential resource to guide policy makers in choice of first line antimalarial drugs, drugs for intermittent preventive treatment (IPT) and prophylactic drugs for travellers.
170.
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
Aaron
L
Sarver,
Amy
J
French,
Pedro
M
Borralho,
Venugopal
Thayanithy,
Ann
L
Oberg,
Kevin
AT
Silverstein,
Bruce
W
Morlan,
Shaun
M
Riska,
Lisa
A
Boardman,
Julie
M
Cunningham,
Subbaya
Subramanian,
Liang
Wang,
Tom
C
Smyrk,
Cecilia
MP
Rodrigues,
Stephen
N
Thibodeau,
Clifford
J
Steer
BMC Cancer 2009, 9 :401 (18 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
171.
An ontology for cell types
Jonathan
Bard,
Seung
Y
Rhee,
Michael
Ashburner
Genome Biology 2005, 6 :R21 (14 January 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
An ontology for cell types that covers the prokaryotic, fungal, animal and plant worlds is described. It includes over 680 cell types. These cell types are classified under several generic categories and are organized as a directed acyclic graph.
172.
Isolation by distance, web service
Jeffrey
L
Jensen,
Andrew
J
Bohonak,
Scott
T
Kelley
BMC Genetics 2005, 6 :13 (11 March 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
173.
Changing computational research. The challenges ahead
Cameron
Neylon,
Jan
Aerts,
C
Brown,
Simon
J
Coles,
Les
Hatton,
Daniel
Lemire,
K
Millman,
Peter
Murray-Rust,
Fernando
Perez,
Neil
Saunders,
Nigam
Shah,
Arfon
Smith,
Gaël
Varoquaux,
Egon
Willighagen
Source Code for Biology and Medicine 2012, 7 :2 (28 May 2012)
Abstract | Full text | PDF | PubMed
174.
Restoration of disk height through non-surgical spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort study
Christian
C
Apfel,
Ozlem
S
Cakmakkaya,
William
Martin,
Charlotte
Richmond,
Alex
Macario,
Elizabeth
George,
Maximilian
Schaefer,
Joseph
V
Pergolizzi
BMC Musculoskeletal Disorders 2010, 11 :155 (8 July 2010)
Abstract | Full text | PDF | PubMed
175.
Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
Dong
Sohn,
Jeremy
Sokolove,
Orr
Sharpe,
Jennifer
C
Erhart,
Piyanka
E
Chandra,
Lauren
J
Lahey,
Tamsin
M
Lindstrom,
Inyong
Hwang,
Katherine
A
Boyer,
Thomas
P
Andriacchi,
William
H
Robinson
Arthritis Research & Therapy 2012, 14 :R7 (8 January 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central