1.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Suzanne
A
Eccles,
Eric
O
Aboagye,
Simak
Ali,
Annie
S
Anderson,
Jo
Armes,
Fedor
Berditchevski,
Jeremy
P
Blaydes,
Keith
Brennan,
Nicola
J
Brown,
Helen
E
Bryant,
Nigel
J
Bundred,
Joy
M
Burchell,
Anna
M
Campbell,
Jason
S
Carroll,
Robert
B
Clarke,
Charlotte
E
Coles,
Gary
JR
Cook,
Angela
Cox,
Nicola
J
Curtin,
Lodewijk
V
Dekker,
Isabel
dos Santos Silva,
Stephen
W
Duffy,
Douglas
F
Easton,
Diana
M
Eccles,
Dylan
R
Edwards,
Joanne
Edwards,
D
Evans,
Deborah
F
Fenlon,
James
M
Flanagan,
Claire
Foster
et al.
Breast Cancer Research 2013, 15 :R92 (1 October 2013)
Abstract | Full text | PDF
|
Editor’s summary
Current knowledge 'gaps' in the understanding of breast cancer are examined, and research should focus on these to improve future clinical care.
2.
LIHNCS - Lugol’s iodine in head and neck cancer surgery: a multicentre, randomised controlled trial assessing the effectiveness of Lugol’s iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma: study protocol for a randomised controlled trial
James
A
McCaul,
James
A
Cymerman,
Stuart
Hislop,
Chris
McConkey,
Jeremy
McMahon,
Hisham
Mehanna,
Richard
Shaw,
David
N
Sutton,
Janet
Dunn
Trials 2013, 14 :310 (24 September 2013)
Abstract | Full text | PDF | PubMed
3.
Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi
Panagiotis
Ioannidis,
Kelly
L
Johnston,
David
R
Riley,
Nikhil
Kumar,
James
R
White,
Karen
T
Olarte,
Sandra
Ott,
Luke
J
Tallon,
Jeremy
M
Foster,
Mark
J
Taylor,
Julie
C
Dunning Hotopp
BMC Genomics 2013, 14 :639 (22 September 2013)
Abstract | Full text | PDF | PubMed
4.
Removing financial barriers to access reproductive, maternal and newborn health services: the challenges and policy implications for human resources for health
Barbara
McPake,
Sophie
Witter,
Tim
Ensor,
Suzanne
Fustukian,
David
Newlands,
Tim
Martineau,
Yotamu
Chirwa
Human Resources for Health 2013, 11 :46 (22 September 2013)
Abstract | Provisional PDF
| PubMed
5.
Control of household air pollution for child survival: estimates for intervention impacts
Nigel
G
Bruce,
Mukesh
K
Dherani,
Jai
K
Das,
Kalpana
Balakrishnan,
Heather
Adair-Rohani,
Zulfiqar
A
Bhutta,
Dan
Pope
BMC Public Health 2013, 13 (Suppl 3):S8 (17 September 2013)
Abstract | Full text | PDF
6.
Evaluating harm associated with anti-malarial drugs: a survey of methods used by clinical researchers to elicit, assess and record participant-reported adverse events and related data
Elizabeth
N
Allen,
Clare
IR
Chandler,
Nyaradzo
Mandimika,
Cheryl
Pace,
Ushma
Mehta,
Karen
I
Barnes
Malaria Journal 2013, 12 :325 (16 September 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
It is critical to evaluate the safety of anti-malarial drugs being deployed in large, diverse populations. When investigating drug effects, study results are influenced by the methods used to collect, assess, record and report outcomes. This survey compares some of the methods that are used.
7.
Using Caenorhabditis elegans to fight human neurodegenerative diseases
Xi
Chen,
Brian
Kraemer,
Jeff
Barclay,
Robert
Burgoyne,
Alan
Morgan
Molecular Neurodegeneration 2013, 8 (Suppl 1):P12 (13 September 2013)
Full text | PDF
8.
Participatory study of medicinal plants used in the control of gastrointestinal parasites in donkeys in Eastern Shewa and Arsi zones of Oromia region, Ethiopia
Claire
E
Scantlebury,
Laura
Peachey,
Jane
Hodgkinson,
Jacqui
B
Matthews,
Andrew
Trawford,
Getachew
Mulugeta,
Gebre
Tefera,
Gina
L
Pinchbeck
BMC Veterinary Research 2013, 9 :179 (11 September 2013)
Abstract | Full text | PDF | PubMed
9.
Modeling national average household concentrations of PM2.5 from solid cookfuel use for the global burden of disease -2010 assessment: results from cross-sectional assessments in India
Kalpana
Balakrishnan,
Santu
Ghosh,
Bhaswati
Ganguli,
Sankar
Sambandam,
Nigel
Bruce,
Douglas
F
Barnes,
Kirk
R
Smith
Environmental Health 2013, 12 :77 (11 September 2013)
Abstract | Provisional PDF
| PubMed
10.
A cross-sectional study of frequency and factors associated with dog walking in 9–10 year old children in Liverpool, UK
Carri
Westgarth,
Lynne
M
Boddy,
Gareth
Stratton,
Alexander
J
German,
Rosalind
M
Gaskell,
Karen
P
Coyne,
Peter
Bundred,
Sandra
McCune,
Susan
Dawson
BMC Public Health 2013, 13 :822 (10 September 2013)
Abstract | Full text | PDF | PubMed
11.
Screening for alcohol-related liver damage in the community: findings from the PrevAIL (Preventing Alcohol Harm in Liverpool) Study
Penny
A
Cook,
Michela
Morleo,
David
Billington,
Mark
Gabbay,
Nick
Sheron,
Ian
T
Gilmore,
Mark
A
Bellis
Addiction Science & Clinical Practice 2013, 8 (Suppl 1):A18 (4 September 2013)
Full text | PDF
12.
A UK validation of a general measure of subjective well-being: the modified BBC subjective well-being scale (BBC-SWB)
Eleanor
Pontin,
Matthias
Schwannauer,
Sara
Tai,
Peter
Kinderman
Health and Quality of Life Outcomes 2013, 11 :150 (3 September 2013)
Abstract | Full text | PDF | PubMed
13.
Effect of malaria transmission reduction by insecticide-treated bed nets (ITNs) on the genetic diversity of Plasmodium falciparum merozoite surface protein (MSP-1) and circumsporozoite (CSP) in western Kenya
Simon
K
Kariuki,
James
Njunge,
Ann
Muia,
Geofrey
Muluvi,
Wangeci
Gatei,
Feiko
ter Kuile,
Dianne
J
Terlouw,
William
A
Hawley,
Penelope
A
Phillips-Howard,
Bernard
L
Nahlen,
Kim
A
Lindblade,
Mary
J
Hamel,
Laurence
Slutsker,
Ya
Shi
Malaria Journal 2013, 12 :295 (27 August 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The study looked at parasite diversity over time (MSP-1 and CSP haplotypes) in an area in western Kenya where a large community-based ITN trial was based. No obvious pressure on parasite diversity was detected in the trial site.
14.
Identification of key structural elements for neuronal calcium sensor-1 function in the regulation of the temperature-dependency of locomotion in C. elegans
Victoria
M
Martin,
James
R
Johnson,
Lee
P
Haynes,
Jeff
W
Barclay,
Robert
D
Burgoyne
Molecular Brain 2013, 6 :39 (27 August 2013)
Abstract | Full text | PDF | PubMed
15.
Chronic obstructive pulmonary disease and exacerbations: Patient insights from the global Hidden Depths of COPD survey
Neil
Barnes,
Peter
MA
Calverley,
Alan
Kaplan,
Klaus
F
Rabe
BMC Pulmonary Medicine 2013, 13 :54 (23 August 2013)
Abstract | Full text | PDF | PubMed
16.
Valuation of traits of indigenous sheep using hedonic pricing in Central Ethiopia
Zelalem
G
Terfa,
Aynalem
Haile,
Derek
Baker,
Girma
T
Kassie
Agricultural and Food Economics 2013, 1 :6 (20 August 2013)
Abstract | Full text | PDF
17.
Personalizing health care: feasibility and future implications
Brian
Godman,
Alexander
E
Finlayson,
Parneet
K
Cheema,
Eva
Zebedin-Brandl,
Inaki
Gutiérrez-Ibarluzea,
Jan
Jones,
Rickard
E
Malmström,
Elina
Asola,
Christoph
Baumgärtel,
Marion
Bennie,
Iain
Bishop,
Anna
Bucsics,
Stephen
Campbell,
Eduardo
Diogene,
Alessandra
Ferrario,
Jurij
Fürst,
Kristina
Garuoliene,
Miguel
Gomes,
Katharine
Harris,
Alan
Haycox,
Harald
Herholz,
Krystyna
Hviding,
Saira
Jan,
Marija
Kalaba,
Christina
Kvalheim,
Ott
Laius,
Sven-Ake
Lööv,
Kamila
Malinowska,
Andrew
Martin,
Laura
McCullagh
et al.
BMC Medicine 2013, 11 :179 (13 August 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Brian Godman and colleagues review the challenges and concerns associated with personalized medicine, emphasizing that it has the potential to revolutionize care, but knowledge from a payer’s perspective must be integrated to move forwards.
18.
The second study of infectious intestinal disease (IID2): increased rates of recurrent diarrhoea in individuals aged 65 years and above
Clarence
C
Tam,
Laura
Viviani,
Laura
C
Rodrigues,
Sarah
J
O’Brien
BMC Public Health 2013, 13 :739 (9 August 2013)
Abstract | Full text | PDF
19.
Generalist solutions to complex problems: generating practice-based evidence - the example of managing multi-morbidity
Joanne
Reeve,
Tom
Blakeman,
George
K
Freeman,
Larry
A
Green,
Paul
A
James,
Peter
Lucassen,
Carmel
M
Martin,
Joachim
P
Sturmberg,
Chris
van Weel
BMC Family Practice 2013, 14 :112 (7 August 2013)
Abstract | Full text | PDF | PubMed
20.
Electrical stimulation modulates Wnt signaling and regulates genes for the motor endplate and calcium binding in muscle of rats with spinal cord transection
Yong
Wu,
Lauren
Collier,
Weiping
Qin,
Graham
Creasey,
William
A
Bauman,
Jonathan
Jarvis,
Christopher
Cardozo
BMC Neuroscience 2013, 14 :81 (2 August 2013)
Abstract | Full text | PDF | PubMed
21.
Clustering of host-seeking activity of Anopheles gambiae mosquitoes at the top surface of a human-baited bed net
Amy
Lynd,
Philip
J
McCall
Malaria Journal 2013, 12 :267 (31 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Simple and elegant experiments demonstrating that Anopheles gambiae preferentially contacts an untreated bed net by approaching from above, near the sleeper¿s head.
22.
Factors associated with change in exacerbation frequency in COPD
Gavin
C
Donaldson,
Hanna
Müllerova,
Nicholas
Locantore,
John
R
Hurst,
Peter
MA
Calverley,
Jorgen
Vestbo,
Antonio
Anzueto,
Jadwiga
A
Wedzicha
Respiratory Research 2013, 14 :79 (30 July 2013)
Abstract | Full text | PDF | PubMed
23.
The genome and transcriptome of the enteric parasite Entamoeba invadens , a model for encystation
Gretchen
M
Ehrenkaufer,
Gareth
D
Weedall,
Daryl
Williams,
Hernan
A
Lorenzi,
Elisabet
Caler,
Neil
Hall,
Upinder
Singh
Genome Biology 2013, 14 :R77 (26 July 2013)
Abstract | Full text | PDF | PubMed | f1000
|
Editor’s summary
Genome and transcriptome analyses of Entamoeba invadens reveal insights into the process of encystation and its role in pathogenicity
24.
True polyandry and pseudopolyandry: why does a monandrous fly remate?
David
N
Fisher,
Rowan
J
Doff,
Tom A
R
Price
BMC Evolutionary Biology 2013, 13 :157 (25 July 2013)
Abstract | Full text | PDF | PubMed
25.
Sub-inhibitory concentrations of some antibiotics can drive diversification of Pseudomonas aeruginosa populations in artificial sputum medium
Elli
A
Wright,
Joanne
L
Fothergill,
Steve
Paterson,
Michael
A
Brockhurst,
Craig
Winstanley
BMC Microbiology 2013, 13 :170 (23 July 2013)
Abstract | Full text | PDF | PubMed