1.
Polyploidization increases meiotic recombination frequency in Arabidopsis
Ales
Pecinka,
Wei
Fang,
Marc
Rehmsmeier,
Avraham
A
Levy,
Ortrun
Mittelsten Scheid
BMC Biology 2011, 9 :24 (21 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
In evolutionary terms, polyploidy has both costs and benefits for an organism. Help in quantifying these is given by an elegant assay involving fluorescent Arabidopsis seeds, which shows that polyploids have an elevated rate of meiotic recombination.
2.
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation
Hubert
Hackl,
Thomas
Burkard,
Alexander
Sturn,
Renee
Rubio,
Alexander
Schleiffer,
Sun
Tian,
John
Quackenbush,
Frank
Eisenhaber,
Zlatko
Trajanoski
Genome Biology 2005, 6 :R108 (19 December 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
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Editor’s summary
In-depth bioinformatics analyses of expressed sequence tags found to be differentially expressed during differentiation of 3T3-L1 pre-adipocyte cells were combined with de novo functional annotation and mapping onto known pathways to generate a molecular atlas of fat-cell development.
3.
MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins
Sebastian
Maurer-Stroh,
Masaki
Gouda,
Maria
Novatchkova,
Alexander
Schleiffer,
Georg
Schneider,
Fernanda
L
Sirota,
Michael
Wildpaner,
Nobuhiro
Hayashi,
Frank
Eisenhaber
Genome Biology 2004, 5 :R21 (13 February 2004)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
MYRbase is a database of glycine myristoylation in eukaryotes. This study shows that the functional spectrum of myristoylated proteins has been underestimated and five membrane-attachment factors that occur frequently with myristoylation have been classified.
4.
Refinement and prediction of protein prenylation motifs
Sebastian
Maurer-Stroh,
Frank
Eisenhaber
Genome Biology 2005, 6 :R55 (27 May 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Three prenylation motif predictors are presented that allow discrimination between proteins that are unique substrates of farnesyltransferase (FT) and those that can be alternatively processed by geranylgeranyltransferase I (GGT1).
5.
Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo
Wolfgang
Benetka,
Manfred
Koranda,
Sebastian
Maurer-Stroh,
Fritz
Pittner,
Frank
Eisenhaber
BMC Biochemistry 2006, 7 :6 (28 February 2006)
Abstract | Full text | PDF | PubMed
6.
Large-scale mapping of mutations affecting zebrafish development
Robert
Geisler,
Gerd-Jörg
Rauch,
Silke
Geiger-Rudolph,
Andrea
Albrecht,
Frauke
van Bebber,
Andrea
Berger,
Elisabeth
Busch-Nentwich,
Ralf
Dahm,
Marcus
PS
Dekens,
Christopher
Dooley,
Alexandra
F
Elli,
Ines
Gehring,
Horst
Geiger,
Maria
Geisler,
Stefanie
Glaser,
Scott
Holley,
Matthias
Huber,
Andy
Kerr,
Anette
Kirn,
Martina
Knirsch,
Martina
Konantz,
Axel
M
Küchler,
Florian
Maderspacher,
Stephan
C
Neuhauss,
Teresa
Nicolson,
Elke
A
Ober,
Elke
Praeg,
Russell
Ray,
Brit
Rentzsch,
Jens
M
Rick
et al.
BMC Genomics 2007, 8 :11 (9 January 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
7.
Protein prenyltransferases
Sebastian
Maurer-Stroh,
Stefan
Washietl,
Frank
Eisenhaber
Genome Biology 2003, 4 :212 (1 April 2003)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Three different protein prenyltransferases catalyze the attachment of prenyl lipid anchors to a variety of eukaryotic proteins. Farnesyltransferase-inhibitor drugs have been developed as anti-cancer agents and may also be able to treat several other diseases.
8.
The ring between ring fingers (RBR) protein family
Birgit
Eisenhaber,
Nina
Chumak,
Frank
Eisenhaber,
Marie-Theres
Hauser
Genome Biology 2007, 8 :209 (15 March 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
An overview of the large and functionally diverse RBR protein family that mediates protein-protein interactions of various kinds in development and disease.
9.
A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database
José
L
Jiménez,
Björn
Hegemann,
James
RA
Hutchins,
Jan-Michael
Peters,
Richard
Durbin
Genome Biology 2007, 8 :R90 (23 May 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
mtcPTM is a new database of phosphorylated protein sequences and atomic models. Analysis of the phosphosites in mtcPTM showed that phosphorylation sites are found in a highly heterogeneous range of structural and sequence contexts.
10.
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease
Rainer
Zenz,
Robert
Eferl,
Clemens
Scheinecker,
Kurt
Redlich,
Josef
Smolen,
Helia
B
Schonthaler,
Lukas
Kenner,
Erwin
Tschachler,
Erwin
F
Wagner
Arthritis Research & Therapy 2008, 10 :201 (18 January 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
11.
From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach
Astrid
R
Mach-Aigner,
Karin
Grosstessner-Hain,
Marcio
J
Poças-Fonseca,
Karl
Mechtler,
Robert
L
Mach
BMC Genomics 2010, 11 :644 (18 November 2010)
Abstract | Full text | PDF | PubMed
12.
Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors
Sara
Molatore,
Eva
Kiermaier,
Christian
B
Jung,
Misu
Lee,
Elke
Pulz,
Heinz
Höfler,
Michael
J
Atkinson,
Natalia
S
Pellegata
Molecular Cancer 2010, 9 :116 (21 May 2010)
Abstract | Full text | PDF | PubMed
13.
Patterns of perceptions of workplace violence in the Portuguese health care sector
Paulo
Ferrinho,
André
Biscaia,
Inês
Fronteira,
Isabel
Craveiro,
Ana
Antunes,
Claudia
Conceição,
Isabel
Flores,
Osvaldo
Santos
Human Resources for Health 2003, 1 :11 (7 November 2003)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
14.
Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation
Maxime
Bouchard,
Dominique
de Caprona,
Meinrad
Busslinger,
Pinxian
Xu,
Bernd
Fritzsch
BMC Developmental Biology 2010, 10 :89 (20 August 2010)
Abstract | Full text | PDF | PubMed
15.
Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction
Nedim
Mujezinovic,
Georg
Schneider,
Michael
Wildpaner,
Karl
Mechtler,
Frank
Eisenhaber
BMC Genomics 2010, 11 (Suppl 1):S13 (10 February 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
16.
Comparison of different methods for preparation and characterization of total RNA from cartilage samples to uncover osteoarthritis in vivo
Anke
Ruettger,
Steffi
Neumann,
Bernd
Wiederanders,
René
Huber
BMC Research Notes 2010, 3 :7 (18 January 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
17.
Direct cooling of the catheter tip increases safety for CMR-guided electrophysiological procedures
Theresa
Reiter,
Daniel
Gensler,
Oliver
Ritter,
Ingo
Weiss,
Wolfgang
Geistert,
Ralf
Kaufmann,
Sabine
Hoffmeister,
Michael
T
Friedrich,
Stefan
Wintzheimer,
Markus
Düring,
Peter
Nordbeck,
Peter
M
Jakob,
Mark
E
Ladd,
Harald
H
Quick,
Wolfgang
R
Bauer
Journal of Cardiovascular Magnetic Resonance 2012, 14 :12 (1 February 2012)
Abstract | Full text | PDF | PubMed
18.
Establishment of a Cre/loxP recombination system for N-terminal epitope tagging of genes in Tetrahymena
Clara
Busch,
Alexander
Vogt,
Kazufumi
Mochizuki
BMC Microbiology 2010, 10 :191 (13 July 2010)
Abstract | Full text | PDF | PubMed
19.
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
Maria
Novatchkova,
Andreas
Bachmair,
Birgit
Eisenhaber,
Frank
Eisenhaber
BMC Bioinformatics 2005, 6 :22 (7 February 2005)
Abstract | Full text | PDF | PubMed
20.
Dynamic localisation of Ran GTPase during the cell cycle
James
RA
Hutchins,
William
J
Moore,
Paul
R
Clarke
BMC Cell Biology 2009, 10 :66 (18 September 2009)
Abstract | Full text | PDF | PubMed
21.
Application of a sensitive collection heuristic for very large protein families: Evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases
Georg
Schneider,
Georg
Neuberger,
Michael
Wildpaner,
Sun
Tian,
Igor
Berezovsky,
Frank
Eisenhaber
BMC Bioinformatics 2006, 7 :164 (21 March 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
22.
Nuclear distribution and chromatin association of DNA polymerase α -primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast
Xiaowen
Yang,
Juraj
Gregan,
Karola
Lindner,
Hedi
Young,
Stephen
E
Kearsey
BMC Molecular Biology 2005, 6 :13 (7 June 2005)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
23.
Comparative analysis of sequence features involved in the recognition of tandem splice sites
Ralf
Bortfeldt,
Stefanie
Schindler,
Karol
Szafranski,
Stefan
Schuster,
Dirk
Holste
BMC Genomics 2008, 9 :202 (30 April 2008)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
24.
Reannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenoviruses
Stefan
Washietl,
Frank
Eisenhaber
BMC Bioinformatics 2003, 4 :55 (7 November 2003)
Abstract | Full text | PDF | PubMed
25.
Induction of HIV mucosal immunity at distal sites after encapsulation of NOD1 and NOD2 ligands in biodegradable nanocarriers
V
Pavot,
N
Rochereau,
V
Lahaye,
C
Genin,
E
Perouzel,
T
Lioux,
C
Primard,
T
Delair,
S
Paul,
B
Verrier
Retrovirology 2012, 9 (Suppl 2):P194 (13 September 2012)
Full text | PDF