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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at MD ANDERSON HOSPITAL

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1.

Research   Open Access

Presence of anaplastic lymphoma kinase in inflammatory breast cancer

Fredika M Robertson, Emanuel F Petricoin III, Steven J Van Laere, Francois Bertucci, Khoi Chu, Sandra V Fernandez, Zhaomei Mu, Katherine Alpaugh, Jianming Pei, Rita Circo, Julia Wulfkuhle, Zaiming Ye, Kimberly M Boley, Hui Liu, Ricardo Moraes, Xuejun Zhang, Ruggero DeMaria, Sanford H Barsky, Guoxian Sun, Massimo Cristofanilli SpringerPlus 2013, 2:497 (1 October 2013)

Abstract | Full text | PDF

2.

Research   Open Access

Integrative network-based Bayesian analysis of diverse genomics data

Wenting Wang, Veerabhadran Baladandayuthapani, Chris C Holmes, Kim-Anh Do BMC Bioinformatics 2013, 14(Suppl 13):S8 (1 October 2013)

Abstract | Full text | PDF

3.

Research   Open Access

Bayesian methods for expression-based integration of various types of genomics data

Elizabeth M Jennings, Jeffrey S Morris, Raymond J Carroll, Ganiraju C Manyam, Veerabhadran Baladandayuthapani EURASIP Journal on Bioinformatics and Systems Biology 2013, 2013:13 (21 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Fractal-like kinetics of intracellular enzymatic reactions: a chemical framework of endotoxin tolerance and a possible non-specific contribution of macromolecular crowding to cross-tolerance

Catalin Vasilescu, Mircea Olteanu, Paul Flondor, George A Calin Theoretical Biology and Medical Modelling 2013, 10:55 (14 September 2013)

Abstract | Full text | PDF | PubMed

5.

Research   Open Access

Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells

Julia Billiard, Jennifer B Dennison, Jacques Briand, Roland S Annan, Deping Chai, Mariela Colón, Christopher S Dodson, Seth A Gilbert, Joel Greshock, Junping Jing, Hong Lu, Jeanelle E McSurdy-Freed, Lisa A Orband-Miller, Gordon B Mills, Chad J Quinn, Jessica L Schneck, Gilbert F Scott, Anthony N Shaw, Gregory M Waitt, Richard F Wooster, Kevin J Duffy Cancer & Metabolism 2013, 1:19 (6 September 2013)

Abstract | Full text | PDF |  Editor’s summary

Quinoline 3-sulfonamids were found to inhibit lactate dehydrogenease, a key driver of oncogenesis through altered cell metabolism, providing information about a potential new class of therapeutics.

6.

Research article   Open Access Highly Accessed

Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency

Rachel L Atkinson, Wei T Yang, Daniel G Rosen, Melissa D Landis, Helen Wong, Michael T Lewis, Chad J Creighton, Krystal R Sexton, Sue G Hilsenbeck, Aysegul A Sahin, Abenaa M Brewster, Wendy A Woodward, Jenny C Chang Breast Cancer Research 2013, 15:R77 (4 September 2013)

Abstract | Provisional PDF | PubMed

7.

Research   Open Access

Expression of CD44v6 and integrin-β1 for the prognosis evaluation of pancreatic cancer patients after cryosurgery

Gang Zhou, David Chiu, Dajiang Qin, Lizhi Niu, Jinlei Cai, Lihua He, Dongfeng Tan, Kecheng Xu Diagnostic Pathology 2013, 8:146 (2 September 2013)

Abstract | Full text | PDF | PubMed

8.

Research   Open Access

Status of the anaplastic lymphoma kinase (ALK) gene in inflammatory breast carcinoma

Savitri Krishnamurthy, Wendy Woodward, Wei Yang, James M Reuben, James Tepperberg, Dai Ogura, Shin-ichiro Niwa, Lei Huo, Yun Gong, Randa El-Zein, Ana M Gonzalez-Angulo, Mariana Chavez-MacGregor, Ricardo Alvarez, Anthony Lucci, Vicente Valero, Naoto T Ueno SpringerPlus 2013, 2:409 (28 August 2013)

Abstract | Full text | PDF

9.

Research   Open Access

Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers

Shaohua Peng, Chad J Creighton, Yiqun Zhang, Banibrata Sen, Tuhina Mazumdar, Jeffery N Myers, Adrian Woolfson, Matthew V Lorenzi, Diana Bell, Michelle D Williams, Faye M Johnson Journal of Translational Medicine 2013, 11:198 (27 August 2013)

Abstract | Full text | PDF | PubMed

10.

Software   Open Access Highly Accessed

BreakTrans: uncovering the genomic architecture of gene fusions

Ken Chen, Nicholas E Navin, Yong Wang, Heather K Schmidt, John W Wallis, Beifang Niu, Xian Fan, Hao Zhao, Michael D Mclellan, Katherine A Hoadley, Elaine R Mardis, Timothy J Ley, Charles M Perou, Richard K Wilson, Li Ding Genome Biology 2013, 14:R87 (23 August 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A new bioinformatic tool for the detection of cancer-related gene fusions and underlying genomic structural rearrangements

11.

Research   Open Access

LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

Fanny Dupuy, Takla Griss, Julianna Blagih, Gäelle Bridon, Daina Avizonis, Chen Ling, Zhifeng Dong, Doris R Siwak, Matthew G Annis, Gordon B Mills, William J Muller, Peter M Siegel, Russell G Jones Cancer & Metabolism 2013, 1:18 (14 August 2013)

Abstract | Full text | PDF |  Editor’s summary

A new mouse model shows the mechanism by which LKB1 causes altered metabolism, apoptosis and tumour initiation in breast cancer.

12.

Research   Open Access

Characterization of aberrant pathways across human cancers

Antti Ylipää, Olli Yli-Harja, Wei Zhang, Matti Nykter BMC Systems Biology 2013, 7(Suppl 1):S1 (12 August 2013)

Abstract | Full text | PDF

13.

Research   Open Access

A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis

Loretta Mancinelli, Teresa Secca, Paula M De Angelis, Francesco Mancini, Matteo Marchesini, Cristiano Marinelli, Lanfranco Barberini, Francesco Grignani Cell Division 2013, 8:11 (6 August 2013)

Abstract | Full text | PDF | PubMed

14.

Review   Open Access

Immunomodulation therapy with lenalidomide in follicular, transformed and diffuse large B cell lymphoma: current data on safety and efficacy

Madhav Desai, Kate J Newberry, Jorge Romaguera, Liang Zhang, Zhishuo Ou, Michael Wang Journal of Hematology & Oncology 2013, 6:55 (2 August 2013)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access Highly Accessed

Comprehensive characterization of malignant phyllodes tumor by whole genomic and proteomic analysis: biological implications for targeted therapy opportunities

Denis Jardim, Anthony Conley, Vivek Subbiah Orphanet Journal of Rare Diseases 2013, 8:112 (30 July 2013)

Abstract | Full text | PDF | PubMed

16.

Review   Open Access

Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors

Willem W Overwijk, Ena Wang, Francesco M Marincola, Hans-Georg Rammensee, Nicholas P Restifo, Journal for ImmunoTherapy of Cancer 2013, 1:11 (29 July 2013)

Abstract | Full text | PDF

17.

Research article   Open Access Highly Accessed

Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis

Mohana Ray, Steve Goldstein, Shiguo Zhou, Konstantinos Potamousis, Deepayan Sarkar, Michael A Newton, Elizabeth Esterberg, Christina Kendziorski, Oliver Bogler, David C Schwartz BMC Genomics 2013, 14:505 (26 July 2013)

Abstract | Full text | PDF | PubMed

18.

Research article   Open Access Highly Accessed

APOBEC3 inhibits DEAD-END function to regulate microRNA activity

Sara Ali, Namrata Karki, Chitralekha Bhattacharya, Rui Zhu, Donna A MacDuff, Mark D Stenglein, April J Schumacher, Zachary L Demorest, Reuben S Harris, Angabin Matin, Sita Aggarwal BMC Molecular Biology 2013, 14:16 (26 July 2013)

Abstract | Full text | PDF | PubMed

19.

Research   Open Access

Predicted risks of radiogenic cardiac toxicity in two pediatric patients undergoing photon or proton radiotherapy

Rui Zhang, Rebecca M Howell, Kenneth Homann, Annelise Giebeler, Phillip J Taddei, Anita Mahajan, Wayne D Newhauser Radiation Oncology 2013, 8:184 (23 July 2013)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access Highly Accessed

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

Keith R Bradnam, Joseph N Fass, Anton Alexandrov, Paul Baranay, Michael Bechner, Inanç Birol, Sébastien Boisvert, Jarrod A Chapman, Guillaume Chapuis, Rayan Chikhi, Hamidreza Chitsaz, Wen-Chi Chou, Jacques Corbeil, Cristian Del Fabbro, T Docking, Richard Durbin, Dent Earl, Scott Emrich, Pavel Fedotov, Nuno A Fonseca, Ganeshkumar Ganapathy, Richard A Gibbs, Sante Gnerre, Élénie Godzaridis, Steve Goldstein, Matthias Haimel, Giles Hall, David Haussler, Joseph B Hiatt, Isaac Y Ho et al. GigaScience 2013, 2:10 (22 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Assemblathon 2 is the largest systematic assessment of how the process of genome assembly is carried out, with 21 participating teams submitting 43 entries based on data from 3 different genomes

21.

Review   Open Access Highly Accessed

Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era

John F Brothers, Kahkeshan Hijazi, Celine Mascaux, Randa A El-Zein, Margaret R Spitz, Avrum Spira BMC Medicine 2013, 11:168 (19 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Early detection of lung cancer is important so patients can be treated as soon as possible; Avrum Spira and colleagues review genetic and genomic biomarkers in development for early diagnosis, and discuss how they could reduce lung cancer deaths.

22.

Research   Open Access

Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma

Lei Jin, Erich M Sturgis, Yang Zhang, Zhigang Huang, Xicheng Song, Chao Li, Qingyi Wei, Guojun Li Molecular Cancer 2013, 12:80 (19 July 2013)

Abstract | Full text | PDF | PubMed

23.

Research   Open Access

Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

Marcus A Lawson, Jennifer M Parrott, Robert H McCusker, Robert Dantzer, Keith W Kelley, Jason C O’Connor Journal of Neuroinflammation 2013, 10:87 (18 July 2013)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

Anesthesia management of patients undergoing hyperthermic isolated limb perfusion with melphalan for melanoma treatment: an analysis of 17 cases

Heiner Ruschulte, Serena Shi, William W Tseng, Kerstin Kolodzie, Philip C Crawford, Darren B Schneider, Mohammed Kashani-Sabet, David Minor, Christian Apfel, Stanley PL Leong BMC Anesthesiology 2013, 13:15 (17 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Hemodynamic changes during melphalan hyperthermic isolated limb perfusion (HILP) as a treatment for unresectable melanoma pose a risk to patients with cardiac compromise, and justify establishing a standard scheme of monitoring, blood testing, and record keeping.

25.

Research article   Open Access Highly Accessed

Cholestasis induces reversible accumulation of periplakin in mouse liver

Shinji Ito, Junko Satoh, Tsutomu Matsubara, Yatrik M Shah, Sung-hoon Ahn, Cherie R Anderson, Weiwei Shan, Jeffrey M Peters, Frank J Gonzalez BMC Gastroenterology 2013, 13:116 (13 July 2013)

Abstract | Full text | PDF | PubMed

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