1.
Presence of anaplastic lymphoma kinase in inflammatory breast cancer
Fredika
M
Robertson,
Emanuel
F
Petricoin III,
Steven
J
Van Laere,
Francois
Bertucci,
Khoi
Chu,
Sandra
V
Fernandez,
Zhaomei
Mu,
Katherine
Alpaugh,
Jianming
Pei,
Rita
Circo,
Julia
Wulfkuhle,
Zaiming
Ye,
Kimberly
M
Boley,
Hui
Liu,
Ricardo
Moraes,
Xuejun
Zhang,
Ruggero
DeMaria,
Sanford
H
Barsky,
Guoxian
Sun,
Massimo
Cristofanilli
SpringerPlus 2013, 2 :497 (1 October 2013)
Abstract | Full text | PDF
2.
Integrative network-based Bayesian analysis of diverse genomics data
Wenting
Wang,
Veerabhadran
Baladandayuthapani,
Chris
C
Holmes,
Kim-Anh
Do
BMC Bioinformatics 2013, 14 (Suppl 13):S8 (1 October 2013)
Abstract | Full text | PDF
3.
Bayesian methods for expression-based integration of various types of genomics data
Elizabeth
M
Jennings,
Jeffrey
S
Morris,
Raymond
J
Carroll,
Ganiraju
C
Manyam,
Veerabhadran
Baladandayuthapani
EURASIP Journal on Bioinformatics and Systems Biology 2013, 2013 :13 (21 September 2013)
Abstract | Full text | PDF | PubMed
4.
Fractal-like kinetics of intracellular enzymatic reactions: a chemical framework of endotoxin tolerance and a possible non-specific contribution of macromolecular crowding to cross-tolerance
Catalin
Vasilescu,
Mircea
Olteanu,
Paul
Flondor,
George
A
Calin
Theoretical Biology and Medical Modelling 2013, 10 :55 (14 September 2013)
Abstract | Full text | PDF | PubMed
5.
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells
Julia
Billiard,
Jennifer
B
Dennison,
Jacques
Briand,
Roland
S
Annan,
Deping
Chai,
Mariela
Colón,
Christopher
S
Dodson,
Seth
A
Gilbert,
Joel
Greshock,
Junping
Jing,
Hong
Lu,
Jeanelle
E
McSurdy-Freed,
Lisa
A
Orband-Miller,
Gordon
B
Mills,
Chad
J
Quinn,
Jessica
L
Schneck,
Gilbert
F
Scott,
Anthony
N
Shaw,
Gregory
M
Waitt,
Richard
F
Wooster,
Kevin
J
Duffy
Cancer & Metabolism 2013, 1 :19 (6 September 2013)
Abstract | Full text | PDF
|
Editor’s summary
Quinoline 3-sulfonamids were found to inhibit lactate dehydrogenease, a key driver of oncogenesis through altered cell metabolism, providing information about a potential new class of therapeutics.
6.
Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency
Rachel
L
Atkinson,
Wei
T
Yang,
Daniel
G
Rosen,
Melissa
D
Landis,
Helen
Wong,
Michael
T
Lewis,
Chad
J
Creighton,
Krystal
R
Sexton,
Sue
G
Hilsenbeck,
Aysegul
A
Sahin,
Abenaa
M
Brewster,
Wendy
A
Woodward,
Jenny
C
Chang
Breast Cancer Research 2013, 15 :R77 (4 September 2013)
Abstract | Provisional PDF
| PubMed
7.
Expression of CD44v6 and integrin-β 1 for the prognosis evaluation of pancreatic cancer patients after cryosurgery
Gang
Zhou,
David
Chiu,
Dajiang
Qin,
Lizhi
Niu,
Jinlei
Cai,
Lihua
He,
Dongfeng
Tan,
Kecheng
Xu
Diagnostic Pathology 2013, 8 :146 (2 September 2013)
Abstract | Full text | PDF | PubMed
8.
Status of the anaplastic lymphoma kinase (ALK) gene in inflammatory breast carcinoma
Savitri
Krishnamurthy,
Wendy
Woodward,
Wei
Yang,
James
M
Reuben,
James
Tepperberg,
Dai
Ogura,
Shin-ichiro
Niwa,
Lei
Huo,
Yun
Gong,
Randa
El-Zein,
Ana
M
Gonzalez-Angulo,
Mariana
Chavez-MacGregor,
Ricardo
Alvarez,
Anthony
Lucci,
Vicente
Valero,
Naoto
T
Ueno
SpringerPlus 2013, 2 :409 (28 August 2013)
Abstract | Full text | PDF
9.
Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers
Shaohua
Peng,
Chad
J
Creighton,
Yiqun
Zhang,
Banibrata
Sen,
Tuhina
Mazumdar,
Jeffery
N
Myers,
Adrian
Woolfson,
Matthew
V
Lorenzi,
Diana
Bell,
Michelle
D
Williams,
Faye
M
Johnson
Journal of Translational Medicine 2013, 11 :198 (27 August 2013)
Abstract | Full text | PDF | PubMed
10.
BreakTrans: uncovering the genomic architecture of gene fusions
Ken
Chen,
Nicholas
E
Navin,
Yong
Wang,
Heather
K
Schmidt,
John
W
Wallis,
Beifang
Niu,
Xian
Fan,
Hao
Zhao,
Michael
D
Mclellan,
Katherine
A
Hoadley,
Elaine
R
Mardis,
Timothy
J
Ley,
Charles
M
Perou,
Richard
K
Wilson,
Li
Ding
Genome Biology 2013, 14 :R87 (23 August 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
A new bioinformatic tool for the detection of cancer-related gene fusions and underlying genomic structural rearrangements
11.
LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer
Fanny
Dupuy,
Takla
Griss,
Julianna
Blagih,
Gäelle
Bridon,
Daina
Avizonis,
Chen
Ling,
Zhifeng
Dong,
Doris
R
Siwak,
Matthew
G
Annis,
Gordon
B
Mills,
William
J
Muller,
Peter
M
Siegel,
Russell
G
Jones
Cancer & Metabolism 2013, 1 :18 (14 August 2013)
Abstract | Full text | PDF
|
Editor’s summary
A new mouse model shows the mechanism by which LKB1 causes altered metabolism, apoptosis and tumour initiation in breast cancer.
12.
Characterization of aberrant pathways across human cancers
Antti
Ylipää,
Olli
Yli-Harja,
Wei
Zhang,
Matti
Nykter
BMC Systems Biology 2013, 7 (Suppl 1):S1 (12 August 2013)
Abstract | Full text | PDF
13.
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis
Loretta
Mancinelli,
Teresa
Secca,
Paula
M
De Angelis,
Francesco
Mancini,
Matteo
Marchesini,
Cristiano
Marinelli,
Lanfranco
Barberini,
Francesco
Grignani
Cell Division 2013, 8 :11 (6 August 2013)
Abstract | Full text | PDF | PubMed
14.
Immunomodulation therapy with lenalidomide in follicular, transformed and diffuse large B cell lymphoma: current data on safety and efficacy
Madhav
Desai,
Kate
J
Newberry,
Jorge
Romaguera,
Liang
Zhang,
Zhishuo
Ou,
Michael
Wang
Journal of Hematology & Oncology 2013, 6 :55 (2 August 2013)
Abstract | Full text | PDF | PubMed
15.
Comprehensive characterization of malignant phyllodes tumor by whole genomic and proteomic analysis: biological implications for targeted therapy opportunities
Denis
Jardim,
Anthony
Conley,
Vivek
Subbiah
Orphanet Journal of Rare Diseases 2013, 8 :112 (30 July 2013)
Abstract | Full text | PDF | PubMed
16.
Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors
Willem
W
Overwijk,
Ena
Wang,
Francesco
M
Marincola,
Hans-Georg
Rammensee,
Nicholas
P
Restifo,
Journal for ImmunoTherapy of Cancer 2013, 1 :11 (29 July 2013)
Abstract | Full text | PDF
17.
Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis
Mohana
Ray,
Steve
Goldstein,
Shiguo
Zhou,
Konstantinos
Potamousis,
Deepayan
Sarkar,
Michael
A
Newton,
Elizabeth
Esterberg,
Christina
Kendziorski,
Oliver
Bogler,
David
C
Schwartz
BMC Genomics 2013, 14 :505 (26 July 2013)
Abstract | Full text | PDF | PubMed
18.
APOBEC3 inhibits DEAD-END function to regulate microRNA activity
Sara
Ali,
Namrata
Karki,
Chitralekha
Bhattacharya,
Rui
Zhu,
Donna
A
MacDuff,
Mark
D
Stenglein,
April
J
Schumacher,
Zachary
L
Demorest,
Reuben
S
Harris,
Angabin
Matin,
Sita
Aggarwal
BMC Molecular Biology 2013, 14 :16 (26 July 2013)
Abstract | Full text | PDF | PubMed
19.
Predicted risks of radiogenic cardiac toxicity in two pediatric patients undergoing photon or proton radiotherapy
Rui
Zhang,
Rebecca
M
Howell,
Kenneth
Homann,
Annelise
Giebeler,
Phillip
J
Taddei,
Anita
Mahajan,
Wayne
D
Newhauser
Radiation Oncology 2013, 8 :184 (23 July 2013)
Abstract | Full text | PDF | PubMed
20.
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
Keith
R
Bradnam,
Joseph
N
Fass,
Anton
Alexandrov,
Paul
Baranay,
Michael
Bechner,
Inanç
Birol,
Sébastien
Boisvert,
Jarrod
A
Chapman,
Guillaume
Chapuis,
Rayan
Chikhi,
Hamidreza
Chitsaz,
Wen-Chi
Chou,
Jacques
Corbeil,
Cristian
Del Fabbro,
T
Docking,
Richard
Durbin,
Dent
Earl,
Scott
Emrich,
Pavel
Fedotov,
Nuno
A
Fonseca,
Ganeshkumar
Ganapathy,
Richard
A
Gibbs,
Sante
Gnerre,
Élénie
Godzaridis,
Steve
Goldstein,
Matthias
Haimel,
Giles
Hall,
David
Haussler,
Joseph
B
Hiatt,
Isaac
Y
Ho
et al.
GigaScience 2013, 2 :10 (22 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Assemblathon 2 is the largest systematic assessment of how the process of genome assembly is carried out, with 21 participating teams submitting 43 entries based on data from 3 different genomes
21.
Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era
John
F
Brothers,
Kahkeshan
Hijazi,
Celine
Mascaux,
Randa
A
El-Zein,
Margaret
R
Spitz,
Avrum
Spira
BMC Medicine 2013, 11 :168 (19 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Early detection of lung cancer is important so patients can be treated as soon as possible; Avrum Spira and colleagues review genetic and genomic biomarkers in development for early diagnosis, and discuss how they could reduce lung cancer deaths.
22.
Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma
Lei
Jin,
Erich
M
Sturgis,
Yang
Zhang,
Zhigang
Huang,
Xicheng
Song,
Chao
Li,
Qingyi
Wei,
Guojun
Li
Molecular Cancer 2013, 12 :80 (19 July 2013)
Abstract | Full text | PDF | PubMed
23.
Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors
Marcus
A
Lawson,
Jennifer
M
Parrott,
Robert
H
McCusker,
Robert
Dantzer,
Keith
W
Kelley,
Jason
C
O’Connor
Journal of Neuroinflammation 2013, 10 :87 (18 July 2013)
Abstract | Full text | PDF | PubMed
24.
Anesthesia management of patients undergoing hyperthermic isolated limb perfusion with melphalan for melanoma treatment: an analysis of 17 cases
Heiner
Ruschulte,
Serena
Shi,
William
W
Tseng,
Kerstin
Kolodzie,
Philip
C
Crawford,
Darren
B
Schneider,
Mohammed
Kashani-Sabet,
David
Minor,
Christian
Apfel,
Stanley
PL
Leong
BMC Anesthesiology 2013, 13 :15 (17 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Hemodynamic changes during melphalan hyperthermic isolated limb perfusion (HILP) as a treatment for unresectable melanoma pose a risk to patients with cardiac compromise, and justify establishing a standard scheme of monitoring, blood testing, and record keeping.
25.
Cholestasis induces reversible accumulation of periplakin in mouse liver
Shinji
Ito,
Junko
Satoh,
Tsutomu
Matsubara,
Yatrik
M
Shah,
Sung-hoon
Ahn,
Cherie
R
Anderson,
Weiwei
Shan,
Jeffrey
M
Peters,
Frank
J
Gonzalez
BMC Gastroenterology 2013, 13 :116 (13 July 2013)
Abstract | Full text | PDF | PubMed