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1.

Software   Open Access

JSME: a free molecule editor in JavaScript

Bruno Bienfait, Peter Ertl Journal of Cheminformatics 2013, 5:24 (21 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

A free molecule editor written in JavaScript was developed and is released under the terms of permissive BSD license. The editor is compatible with JME, has practically the same user interface as well as the web application programming interface.

2.

Commentary   Open Access

Fulani show decreased susceptibility to Plasmodium falciparum infection versus Mossi: data from a community-wide screening and treatment of asymptomatic carriers in Burkina Faso

Alfred B Tiono, Sodiomon B Sirima, Kamal Hamed Malaria Journal 2013, 12:163 (16 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study confirmed that, in the same environment, individuals belonging to the Fulani ethnic group have a lower susceptibility to Plasmodium falciparum infection than Mossi individuals.

3.

Research   Open Access

Potential of patient-reported outcomes as nonprimary endpoints in clinical trials

Ari Gnanasakthy, Sandra Lewis, Marci Clark, Margaret Mordin, Carla DeMuro Health and Quality of Life Outcomes 2013, 11:83 (15 May 2013)

Abstract | Provisional PDF | PubMed

4.

Poster presentation   Open Access

Reduction in oral corticosteroid use in patients with severe allergic (IgE-mediated) asthma receiving omalizumab in a real-world setting

Gert-Jan Braunstahl, Jan Chlumsky, Guy Peachey, Robert Maykut, Chien-Wei Chen Clinical and Translational Allergy 2013, 3(Suppl 1):P13 (3 May 2013)

Full text | PDF

5.

Oral presentation   Open Access

Omalizumab in the treatment of severe allergic (IgE-mediated) asthma: an update on recent developments

Marc Humbert, Janice Canvin, Tamara Kiechle, Phil Lowe, Veit Erpenbeck Clinical and Translational Allergy 2013, 3(Suppl 1):O12 (3 May 2013)

Full text | PDF

6.

Poster presentation   Open Access

Healthcare utilization and indirect cost of treatment associated with severe allergic asthma in a real-world setting

Gert-Jan Braunstahl, Marco Deenstra, Janice Canvin, Guy Peachey, Chien-Wei Chen, Panayiotis Georgiou, Robert Maykut Clinical and Translational Allergy 2013, 3(Suppl 1):P1 (3 May 2013)

Full text | PDF

7.

Research article   Open Access Highly Accessed

Robenacoxib versus meloxicam for the management of pain and inflammation associated with soft tissue surgery in dogs: a randomized, non-inferiority clinical trial

Philippe Gruet, Wolfgang Seewald, Jonathan N King BMC Veterinary Research 2013, 9:92 (2 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A treatment regimen of a new NSAID, robenacoxib, by subcutaneous injection followed by oral tablets, demonstrates good tolerability and non inferior efficacy compared to meloxicam for the management of perioperative pain and inflammation associated with soft tissue surgery in dogs.

8.

Research article   Open Access Highly Accessed

Boceprevir for previously untreated patients with chronic hepatitis C Genotype 1 infection: a US-based cost-effectiveness modeling study

Shannon Allen Ferrante, Jagpreet Chhatwal, Clifford A Brass, Antoine C El Khoury, Fred Poordad, Jean-Pierre Bronowicki, Elamin H Elbasha BMC Infectious Diseases 2013, 13:190 (27 April 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

Indacaterol on dyspnea in chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized placebo-controlled trials

Jiangna Han, Lu Dai, Nanshan Zhong BMC Pulmonary Medicine 2013, 13:26 (25 April 2013)

Abstract | Full text | PDF | PubMed

10.

Meeting abstract   Open Access

Asthma diagnosis and treatment – 1015. Improvements in lung function in an indian population with IgE mediated asthma receiving omalizumab in a real-world setting

Randeep Guleria, Deepak Talwar, Ashok Mahashur, Mangala Kotnis World Allergy Organization Journal 2013, 6(Suppl 1):P15 (23 April 2013)

Full text | PDF

11.

Research   Open Access

Artemisinin-based combination therapy availability and use in the private sector of five AMFm phase 1 countries

Ben Davis, Joel Ladner, Kelley Sams, Ebru Tekinturhan, Donald de Korte, Joseph Saba Malaria Journal 2013, 12:135 (22 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The objective of this study was to assess anti-malarial stock and purchase patterns at private outlets in five Phase 1 countries in the Affordable Medicines Facility-malaria programme, in regard to three of the core AMFm goals: increase the affordability of quality-assured artemisinin combination therapy, increase the availability of ACT, and crowd out artemisinin monotherapies and other substandard therapies.

12.

Research   Open Access

Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation

Xi-Ning Zhu, Dong Hyun Kim, Horng-Ru Lin, Varija N Budhavarapu, Herbert B Rosenbaum, Paul R Mueller, P Renee Yew Cell Division 2013, 8:5 (22 April 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Notch4 is required for tumor onset and perfusion

Maria José Costa, Xiaoqing Wu, Henar Cuervo, Ruchika Srinivasan, Seth K Bechis, Ellen Cheang, Olivera Marjanovic, Thomas Gridley, Christin A Cvetic, Rong A Wang Vascular Cell 2013, 5:7 (20 April 2013)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Resource utilization, costs and treatment patterns of switching and discontinuing treatment of MS patients with high relapse activity

Karina Raimundo, Haijun Tian, Huanxue Zhou, Xin Zhang, Kristijan H Kahler, Neetu Agashivala, Edward Kim BMC Health Services Research 2013, 13:131 (8 April 2013)

Abstract | Full text | PDF | PubMed

15.

Original investigation   Open Access Highly Accessed

Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus – results from an exploratory study

Christine Berndt-Zipfel, Georg Michelson, Markus Dworak, Michael Mitry, Andrea Löffler, Andreas Pfützner, Thomas Forst Cardiovascular Diabetology 2013, 12:59 (8 April 2013)

Abstract | Full text | PDF | PubMed

16.

Research article   Open Access

Rapid initial decline in BCR-ABL1 is associated with superior responses to second-line nilotinib in patients with chronic-phase chronic myeloid leukemia

Andrew M Stein, Giovanni Martinelli, Timothy P Hughes, Martin C Müller, Lan Beppu, Enrico Gottardi, Susan Branford, Simona Soverini, Richard C Woodman, Andreas Hochhaus, Dong-Wook Kim, Giuseppe Saglio, Jerald P Radich BMC Cancer 2013, 13:173 (2 April 2013)

Abstract | Full text | PDF | PubMed

17.

New method   Open Access

A quantitative homogeneous assay for fragile X mental retardation 1 protein

Gabi Schutzius, Dorothee Bleckmann, Sandra Kapps-Fouthier, Francesco di Giorgio, Bernd Gerhartz, Andreas Weiss Journal of Neurodevelopmental Disorders 2013, 5:8 (2 April 2013)

Abstract | Full text | PDF | PubMed

18.

Methodology article   Open Access Highly Accessed

Differential expression analysis for paired RNA-seq data

Lisa M Chung, John P Ferguson, Wei Zheng, Feng Qian, Vincent Bruno, Ruth R Montgomery, Hongyu Zhao BMC Bioinformatics 2013, 14:110 (27 March 2013)

Abstract | Provisional PDF | PubMed

19.

Review   Open Access

Experimental designs for small randomised clinical trials: an algorithm for choice

Catherine Cornu, Behrouz Kassai, Roland Fisch, Catherine Chiron, Corinne Alberti, Renzo Guerrini, Anna Rosati, Gerard Pons, Harm Tiddens, Sylvie Chabaud, Daan Caudri, Clément Ballot, Polina Kurbatova, Anne-Charlotte Castellan, Agathe Bajard, Patrice Nony, Orphanet Journal of Rare Diseases 2013, 8:48 (25 March 2013)

Abstract | Full text | PDF | PubMed

20.

Research   Open Access

Gamma radiation mediated green synthesis of gold nanoparticles using fermented soybean-garlic aqueous extract and their antimicrobial activity

Ahmed Ibrahim El-Batal, Abd-Algawad M Hashem, Noha M Abdelbaky SpringerPlus 2013, 2:129 (23 March 2013)

Abstract | Full text | PDF

21.

Research article   Open Access Highly Accessed

Improving basic and translational science by accounting for litter-to-litter variation in animal models

Stanley E Lazic, Laurent Essioux BMC Neuroscience 2013, 14:37 (22 March 2013)

Abstract | Full text | PDF | PubMed

22.

Oral presentation   Open Access

Reproducibility in cheminformatics and computational chemistry research: certainly we can do better than this

Gregory A Landrum Journal of Cheminformatics 2013, 5(Suppl 1):O4 (22 March 2013)

Full text | PDF

23.

Oral presentation   Open Access

Get your chemistry right with KNIME

Thorsten Meinl, Gregory Landrum Journal of Cheminformatics 2013, 5(Suppl 1):F1 (22 March 2013)

Full text | PDF

24.

Research article   Open Access

Safety and efficacy of everolimus in Chinese patients with metastatic renal cell carcinoma resistant to vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy: an open-label phase 1b study

Jun Guo, Yiran Huang, Xu Zhang, Fangjian Zhou, Yinghao Sun, Shukui Qin, Zhangqun Ye, Hui Wang, Annette Jappe, Patrick Straub, Nicoletta Pirotta, Sven Gogov BMC Cancer 2013, 13:136 (21 March 2013)

Abstract | Full text | PDF | PubMed

25.

Poster presentation   Free

In vitro efficiency of Amikacin Inhale, a novel drug-device delivery system

N Kadrichu, S Boc, K Corkery, P Challoner Critical Care 2013, 17(Suppl 2):P81 (19 March 2013)

Full text | PDF

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