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1.

Research   Open Access

Understanding the sequential activation of Type III and Type VI Secretion Systems in Salmonella typhimurium using Boolean modeling

Chandrani Das, Anirban Dutta, Hannah Rajasingh, Sharmila S Mande Gut Pathogens 2013, 5:28 (30 September 2013)

Abstract | Full text | PDF | PubMed

2.

Software   Open Access

Similarity maps - a visualization strategy for molecular fingerprints and machine-learning methods

Sereina Riniker, Gregory A Landrum Journal of Cheminformatics 2013, 5:43 (24 September 2013)

Abstract | Provisional PDF | PubMed | Graphical abstract

3.

Review   Open Access

Cardiac implications of hypoglycaemia in patients with diabetes – a systematic review

Markolf Hanefeld, Eva Duetting, Peter Bramlage Cardiovascular Diabetology 2013, 12:135 (21 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9

Selina ER Bopp, Evelyn Rodrigo, Gonzalo E González-Páez, Mary Frazer, S Barnes, Clarissa Valim, James Watson, John R Walker, Christian Schmedt, Elizabeth A Winzeler Malaria Journal 2013, 12:316 (11 September 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This paper describes the mapping of a host response locus to chromosome 9 in the mouse in response to infection by P. berghei ANKA strain.

5.

Research   Open Access

Methodological challenges in monitoring new treatments for rare diseases: lessons from the cryopyrin-associated periodic syndrome registry

Hugh Tilson, Paola Primatesta, Dennis Kim, Barbara Rauer, Philip N Hawkins, Hal M Hoffman, Jasmin Kuemmerle-Deschner, Tom van der Poll, Ulrich A Walker Orphanet Journal of Rare Diseases 2013, 8:139 (10 September 2013)

Abstract | Full text | PDF | PubMed

6.

Research   Open Access

Evaluation of two novel tablet formulations of artemether-lumefantrine (Coartem®) for bioequivalence in a randomized, open-label, two-period study

Gilbert Lefèvre, Prafulla Bhad, Jay Jain, Sampath Kalluri, Yi Cheng, Hardik Dave, Daniel S Stein Malaria Journal 2013, 12:312 (8 September 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Bioequivalence of two novel formulations of Coartem in healthy volunteers. These novel formulations are easy to administer and may improve adherence in the treatment of uncomplicated malaria.

7.

Research   Open Access

Drug versus vaccine investment: a modelled comparison of economic incentives

Stéphane A Régnier, Jasper Huels Cost Effectiveness and Resource Allocation 2013, 11:23 (8 September 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Concurrent short-term use of prednisolone with cyclosporine A accelerates pruritus reduction and improvement in clinical scoring in dogs with atopic dermatitis

Ramiro Dip, James Carmichael, Ingrid Letellier, Guenther Strehlau, Elizabeth Roberts, Emmanuel Bensignor, Wayne Rosenkrantz BMC Veterinary Research 2013, 9:173 (3 September 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access

Cytochrome P450 2C19*2 polymorphism in patients with stable coronary heart disease and risk for secondary cardiovascular disease events: results of a long-term follow-up study in routine clinical care

Dietrich Rothenbacher, Michael M Hoffmann, Lutz P Breitling, Iris Rajman, Wolfgang Koenig, Hermann Brenner BMC Cardiovascular Disorders 2013, 13:61 (27 August 2013)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access

PET imaging to non-invasively study immune activation leading to antitumor responses with a 4-1BB agonistic antibody

Helena Escuin-Ordinas, Mark W Elliott, Mohammad Atefi, Michelle Lee, Charles Ng, Liu Wei, Begoña Comin-Anduix, Encarnacion Montecino-Rodriguez, Earl Avramis, Caius Radu, Leslie L Sharp, Antoni Ribas Journal for ImmunoTherapy of Cancer 2013, 1:14 (27 August 2013)

Abstract | Full text | PDF

11.

Research article   Open Access

Efficacy and safety of diclofenac diethylamine 1.16% gel in acute neck pain: a randomized, double-blind, placebo-controlled study

Hans-Georg Predel, Bruno Giannetti, Helmut Pabst, Axel Schaefer, Agnes M Hug, Ian Burnett BMC Musculoskeletal Disorders 2013, 14:250 (21 August 2013)

Abstract | Full text | PDF | PubMed

12.

Study protocol   Open Access Highly Accessed

Efficacy and safety of combination therapy with vildagliptin and metformin versus metformin up-titration in Chinese patients with type 2 diabetes mellitus: study design and rationale of the vision study

Li-Nong Ji, Chang-Yu Pan, Ju-Ming Lu, Hong Li, Qiang Li, Qi-Fu Li, Yong-De Peng, Hao-Ming Tian, Chen Yao, Zhi-Gang Zhao, Ru-Ya Zhang, Xiang-Ling Wang, Lei Wang, Cardiovascular Diabetology 2013, 12:118 (19 August 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Budget impact analysis on erythropoiesis–stimulating agents use for the management of chemotherapy-induced anaemia in Greece

Eleftheria Nikolaidi, Magdalini Hatzikou, Mary Geitona Cost Effectiveness and Resource Allocation 2013, 11:16 (16 July 2013)

Abstract | Full text | PDF | PubMed

14.

Research   Open Access

Efficacy and safety of concentration-controlled everolimus with reduced-dose cyclosporine in Japanese de novo renal transplant patients: 12-month results

Kota Takahashi, Kazuharu Uchida, Norio Yoshimura, Shiro Takahara, Satoshi Teraoka, Rie Teshima, Catherine Cornu-Artis, Eiji Kobayashi Transplantation Research 2013, 2:14 (16 July 2013)

Abstract | Full text | PDF | PubMed

15.

Short Report   Open Access

Identification of the likely translational start of Mycobacterium tuberculosis GyrB

Shantanu Karkare, Amanda C Brown, Tanya Parish, Anthony Maxwell BMC Research Notes 2013, 6:274 (15 July 2013)

Abstract | Full text | PDF | PubMed

16.

Methodology article   Open Access Highly Accessed

Multiplexed Illumina sequencing libraries from picogram quantities of DNA

Sarah K Bowman, Matthew D Simon, Aimee M Deaton, Michael Tolstorukov, Mark L Borowsky, Robert E Kingston BMC Genomics 2013, 14:466 (9 July 2013)

Abstract | Full text | PDF | PubMed

17.

Review   Open Access

Molecular signatures of chronic myeloid leukemia stem cells

Yaoyu Chen, Shaoguang Li Biomarker Research 2013, 1:21 (6 June 2013)

Abstract | Full text | PDF

18.

Research article   Open Access Highly Accessed

Open-source platform to benchmark fingerprints for ligand-based virtual screening

Sereina Riniker, Gregory A Landrum Journal of Cheminformatics 2013, 5:26 (30 May 2013)

Abstract | Full text | PDF | PubMed | Graphical abstract

19.

Research   Open Access

The Caregiver Burden Questionnaire for Heart Failure (CBQ-HF): face and content validity

Louise Humphrey, Karoly Kulich, Celine Deschaseaux, Steven Blackburn, Laura Maguire, Anna Strömberg Health and Quality of Life Outcomes 2013, 11:84 (25 May 2013)

Abstract | Full text | PDF | PubMed

20.

Software   Open Access Highly Accessed

JSME: a free molecule editor in JavaScript

Bruno Bienfait, Peter Ertl Journal of Cheminformatics 2013, 5:24 (21 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary | Graphical abstract

A free molecule editor written in JavaScript was developed and is released under the terms of permissive BSD license. The editor is compatible with JME, has practically the same user interface as well as the web application programming interface.

21.

Commentary   Open Access

Fulani show decreased susceptibility to Plasmodium falciparum infection versus Mossi: data from a community-wide screening and treatment of asymptomatic carriers in Burkina Faso

Alfred B Tiono, Sodiomon B Sirima, Kamal Hamed Malaria Journal 2013, 12:163 (16 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This study confirmed that, in the same environment, individuals belonging to the Fulani ethnic group have a lower susceptibility to Plasmodium falciparum infection than Mossi individuals.

22.

Research   Open Access Highly Accessed

Potential of patient-reported outcomes as nonprimary endpoints in clinical trials

Ari Gnanasakthy, Sandra Lewis, Marci Clark, Margaret Mordin, Carla DeMuro Health and Quality of Life Outcomes 2013, 11:83 (15 May 2013)

Abstract | Full text | PDF | PubMed

23.

Poster presentation   Open Access

Reduction in oral corticosteroid use in patients with severe allergic (IgE-mediated) asthma receiving omalizumab in a real-world setting

Gert-Jan Braunstahl, Jan Chlumsky, Guy Peachey, Robert Maykut, Chien-Wei Chen Clinical and Translational Allergy 2013, 3(Suppl 1):P13 (3 May 2013)

Full text | PDF

24.

Oral presentation   Open Access

Omalizumab in the treatment of severe allergic (IgE-mediated) asthma: an update on recent developments

Marc Humbert, Janice Canvin, Tamara Kiechle, Phil Lowe, Veit Erpenbeck Clinical and Translational Allergy 2013, 3(Suppl 1):O12 (3 May 2013)

Full text | PDF

25.

Poster presentation   Open Access

Healthcare utilization and indirect cost of treatment associated with severe allergic asthma in a real-world setting

Gert-Jan Braunstahl, Marco Deenstra, Janice Canvin, Guy Peachey, Chien-Wei Chen, Panayiotis Georgiou, Robert Maykut Clinical and Translational Allergy 2013, 3(Suppl 1):P1 (3 May 2013)

Full text | PDF

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