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1.

Review   Open Access Highly Accessed

Near-highway pollutants in motor vehicle exhaust: A review of epidemiologic evidence of cardiac and pulmonary health risks

Doug Brugge, John L Durant, Christine Rioux Environmental Health 2007, 6:23 (9 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

Research article   Open Access Highly Accessed

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

Christine M Fillmore, Charlotte Kuperwasser Breast Cancer Research 2008, 10:R25 (26 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

Review   Open Access Highly Accessed

Colistin: recent data on pharmacodynamics properties and clinical efficacy in critically ill patients

Argyris S Michalopoulos, Matthew E Falagas Annals of Intensive Care 2011, 1:30 (2 August 2011)

Abstract | Full text | PDF | PubMed

4.

Review   Open Access Highly Accessed

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

Brandi N Davis, Akiko Hata Cell Communication and Signaling 2009, 7:18 (10 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

Review   Open Access Highly Accessed

Patellofemoral pain syndrome (PFPS): a systematic review of anatomy and potential risk factors

Gregory R Waryasz, Ann Y McDermott Dynamic Medicine 2008, 7:9 (26 June 2008)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access Highly Accessed

Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review

Petros I Rafailidis, Eleni G Mourtzoukou, Ioannis C Varbobitis, Matthew E Falagas Virology Journal 2008, 5:47 (27 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

Review   Open Access Highly Accessed

Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials?

John PA Ioannidis Philosophy, Ethics, and Humanities in Medicine 2008, 3:14 (27 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 2 comments

8.

Research article   Open Access Highly Accessed

Tai Chi on psychological well-being: systematic review and meta-analysis

Chenchen Wang, Raveendhara Bannuru, Judith Ramel, Bruce Kupelnick, Tammy Scott, Christopher H Schmid BMC Complementary and Alternative Medicine 2010, 10:23 (21 May 2010)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access Highly Accessed

Toxicity of polymyxins: a systematic review of the evidence from old and recent studies

Matthew E Falagas, Sofia K Kasiakou Critical Care 2006, 10:R27 (13 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

Review   Free Highly Accessed

Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)

John A Kellum, Norbert Lameire, Critical Care 2013, 17:204 (4 February 2013)

Abstract | Full text | PDF | PubMed

11.

Review   Open Access Highly Accessed

Sex differences in human adipose tissues – the biology of pear shape

Kalypso Karastergiou, Steven R Smith, Andrew S Greenberg, Susan K Fried Biology of Sex Differences 2012, 3:13 (31 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

Research article   Open Access Highly Accessed

The effect of psychosocial factors on breast cancer outcome: a systematic review

Matthew E Falagas, Effie A Zarkadoulia, Eleni N Ioannidou, George Peppas, Christos Christodoulou, Petros I Rafailidis Breast Cancer Research 2007, 9:R44 (17 July 2007)

Abstract | Full text | PDF | PubMed

13.

Review   Open Access Highly Accessed

Histological variants of cutaneous Kaposi sarcoma

Wayne Grayson, Liron Pantanowitz Diagnostic Pathology 2008, 3:31 (25 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

Software   Open Access Highly Accessed

Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data

Byron C Wallace, Christopher H Schmid, Joseph Lau, Thomas A Trikalinos BMC Medical Research Methodology 2009, 9:80 (4 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Meta-Analyst is an intuitive tool for conducting meta-analysis and meta-regression on binary and continuous data and for Bayesian or frequentist analyses of diagnostic and prognostic studies, comparing well with Stata and analyses in the Cochrane Library.

15.

Research article   Open Access Highly Accessed

Healthy-lifestyle behaviors associated with overweight and obesity in US rural children

Alison Tovar, Kenneth Chui, Raymond R Hyatt, Julia Kuder, Vivica I Kraak, Silvina F Choumenkovitch, Alia Hastings, Julia Bloom, Christina D Economos BMC Pediatrics 2012, 12:102 (18 July 2012)

Abstract | Full text | PDF | PubMed

16.

Hypothesis   Open Access Highly Accessed

Neuro-inflammation, blood-brain barrier, seizures and autism

Theoharis C Theoharides, Bodi Zhang Journal of Neuroinflammation 2011, 8:168 (30 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Research article   Open Access Highly Accessed

Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines

Patricia J Keller, Amy F Lin, Lisa M Arendt, Ina Klebba, Ainsley D Jones, Jenny A Rudnick, Theresa A DiMeo , Hannah Gilmore, Douglas M Jefferson, Roger A Graham, Stephen P Naber, Stuart Schnitt, Charlotte Kuperwasser Breast Cancer Research 2010, 12:R87 (21 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

Research article   Open Access Highly Accessed

Post tracheostomy and post intubation tracheal stenosis: Report of 31 cases and review of the literature

Nikolaos Zias, Alexandra Chroneou, Maher K Tabba, Anne V Gonzalez, Anthony W Gray, Carla R Lamb, David R Riker, John F Beamis BMC Pulmonary Medicine 2008, 8:18 (21 September 2008)

Abstract | Full text | PDF | PubMed

19.

Research   Open Access Highly Accessed

Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis

Argyris Michalopoulos, Sofia K Kasiakou, Zefi Mastora, Kostas Rellos, Anastasios M Kapaskelis, Matthew E Falagas Critical Care 2005, 9:R53-R59 (6 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

Research article   Open Access Highly Accessed

Imagable 4T1 model for the study of late stage breast cancer

Kai Tao, Min Fang, Joseph Alroy, G Gary Sahagian BMC Cancer 2008, 8:228 (9 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

Short report   Open Access Highly Accessed

Intravascular lesions of the hand

Liron Pantanowitz, Wayne H Duke Diagnostic Pathology 2008, 3:24 (30 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

Review   Free Highly Accessed

Contrast-induced acute kidney injury and renal support for acute kidney injury: a KDIGO summary (Part 2)

Norbert Lameire, John A Kellum, Critical Care 2013, 17:205 (4 February 2013)

Abstract | Full text | PDF | PubMed

23.

Review   Open Access Highly Accessed

Teratogenicity of depleted uranium aerosols: A review from an epidemiological perspective

Rita Hindin, Doug Brugge, Bindu Panikkar Environmental Health: A Global Access Science Source 2005, 4:17 (26 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Methodology article   Open Access Highly Accessed

Genotyping 1000 yeast strains by next-generation sequencing

Stefan Wilkening, Manu M Tekkedil, Gen Lin, Emilie S Fritsch, Wu Wei, Julien Gagneur, David W Lazinski, Andrew Camilli, Lars M Steinmetz BMC Genomics 2013, 14:90 (9 February 2013)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access Highly Accessed

Antibiotic resistance as a global threat: Evidence from China, Kuwait and the United States

Ruifang Zhang, Karen Eggleston, Vincent Rotimi, Richard J Zeckhauser Globalization and Health 2006, 2:6 (7 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

26.

Research article   Open Access

Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects

Howard A Smithline, Michael Donnino, David J Greenblatt BMC Clinical Pharmacology 2012, 12:4 (4 February 2012)

Abstract | Full text | PDF | PubMed

27.

Review   Open Access Highly Accessed

Review and application of group theory to molecular systems biology

Edward A Rietman, Robert L Karp, Jack A Tuszynski Theoretical Biology and Medical Modelling 2011, 8:21 (22 June 2011)

Abstract | Full text | PDF | PubMed

28.

Research article   Open Access Highly Accessed

Cognitive and memory training in adults at risk of dementia: A Systematic Review

Nicola J Gates, Perminder S Sachdev, Maria A Fiatarone Singh, Michael Valenzuela BMC Geriatrics 2011, 11:55 (25 September 2011)

Abstract | Full text | PDF | PubMed

29.

Research article   Open Access Highly Accessed

The prevalence of obesity in children with autism: a secondary data analysis using nationally representative data from the National Survey of Children's Health

Carol Curtin, Sarah E Anderson, Aviva Must, Linda Bandini BMC Pediatrics 2010, 10:11 (23 February 2010)

Abstract | Full text | PDF | PubMed

30.

Research   Open Access Highly Accessed

Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

Mark W Silby, Ana M Cerdeño-Tárraga, Georgios S Vernikos, Stephen R Giddens, Robert W Jackson, Gail M Preston, Xue-Xian Zhang, Christina D Moon, Stefanie M Gehrig, Scott AC Godfrey, Christopher G Knight, Jacob G Malone, Zena Robinson, Andrew J Spiers, Simon Harris, Gregory L Challis, Alice M Yaxley, David Harris, Kathy Seeger, Lee Murphy, Simon Rutter, Rob Squares, Michael A Quail, Elizabeth Saunders, Konstantinos Mavromatis, Thomas S Brettin, Stephen D Bentley, Joanne Hothersall, Elton Stephens, Christopher M Thomas, Julian Parkhill, Stuart B Levy, Paul B Rainey, Nicholas R Thomson et al. Genome Biology 2009, 10:R51 (11 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Comparison of the genome sequences of three Pseudomonas fluorescens strains reveals a heterogeneity reminiscent of a species complex rather than a single species

31.

Research article   Open Access Highly Accessed

A qualitative study of leadership characteristics among women who catalyze positive community change

Sara C Folta, Rebecca A Seguin, Jennifer Ackerman, Miriam E Nelson BMC Public Health 2012, 12:383 (28 May 2012)

Abstract | Full text | PDF | PubMed

32.

Research   Open Access Highly Accessed

Physical activity, energy requirements, and adequacy of dietary intakes of older persons in a rural Filipino community

Maria Risonar, Pura Rayco-Solon, Judy D Ribaya-Mercado, Juan Solon, Aegina B Cabalda, Lorena W Tengco, Florentino S Solon Nutrition Journal 2009, 8:19 (4 May 2009)

Abstract | Full text | PDF | PubMed

33.

Research article   Open Access

Eating attitudes and food intakes of elite adolescent female figure skaters: a cross sectional study

Johanna Dwyer, Alanna Eisenberg, Kathy Prelack, Won O Song, Kendrin Sonneville, Paula Ziegler Journal of the International Society of Sports Nutrition 2012, 9:53 (13 December 2012)

Abstract | Full text | PDF | PubMed

34.

Review   Open Access Highly Accessed

Perinatal stress, brain inflammation and risk of autism-Review and proposal

Asimenia Angelidou, Shahrzad Asadi, Konstantinos-Dionysios Alysandratos, Anna Karagkouni, Stella Kourembanas, Theoharis C Theoharides BMC Pediatrics 2012, 12:89 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

Research   Open Access Highly Accessed

Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents

Yulia Shamis, Kyle J Hewitt, Mark W Carlson, Mariam Margvelashvilli, Shumin Dong, Catherine K Kuo, Laurence Daheron, Christophe Egles, Jonathan A Garlick Stem Cell Research & Therapy 2011, 2:10 (21 February 2011)

Abstract | Full text | PDF | PubMed

36.

Research   Open Access Highly Accessed

Parent-child interactions and objectively measured child physical activity: a cross-sectional study

Erin Hennessy, Sheryl O Hughes, Jeanne P Goldberg, Raymond R Hyatt, Christina D Economos International Journal of Behavioral Nutrition and Physical Activity 2010, 7:71 (7 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

Research article   Open Access Highly Accessed

Active play and screen time in US children aged 4 to 11 years in relation to sociodemographic and weight status characteristics: a nationally representative cross-sectional analysis

Sarah E Anderson, Christina D Economos, Aviva Must BMC Public Health 2008, 8:366 (22 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

Research article   Open Access

Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met

Kelly L Mueller, Julie M Madden, Gina L Zoratti, Charlotte Kuperwasser, Karin List, Julie L Boerner Breast Cancer Research 2012, 14:R104 (12 July 2012)

Abstract | Full text | PDF | PubMed

39.

Commentary   Open Access Highly Accessed

A Web-based archive of systematic review data

Stanley Ip, Nira Hadar, Sarah Keefe, Christopher Parkin, Ramon Iovin, Ethan M Balk, Joseph Lau Systematic Reviews 2012, 1:15 (21 February 2012)

Abstract | Full text | PDF | PubMed | 1 comment

40.

Research   Open Access

New fat free mass - fat mass model for use in physiological energy balance equations

Diana Thomas, Sai Das, James A Levine, Corby K Martin, Laurel Mayer, Andrew McDougall, Boyd J Strauss, Steven B Heymsfield Nutrition & Metabolism 2010, 7:39 (9 May 2010)

Abstract | Full text | PDF | PubMed

41.

Research article   Open Access Highly Accessed

Epidemiology of constipation in Europe and Oceania: a systematic review

George Peppas, Vangelis G Alexiou, Eleni Mourtzoukou, Matthew E Falagas BMC Gastroenterology 2008, 8:5 (12 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

Research   Open Access

Auto-titrating versus fixed continuous positive airway pressure for the treatment of obstructive sleep apnea: a systematic review with meta-analyses

Stanley Ip, Carolyn D'Ambrosio, Kamal Patel, Ndidiamaka Obadan, Georgios D Kitsios, Mei Chung, Ethan M Balk Systematic Reviews 2012, 1:20 (8 March 2012)

Abstract | Full text | PDF | PubMed

43.

Research   Open Access

The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text

Martin Krallinger, Miguel Vazquez, Florian Leitner, David Salgado, Andrew Chatr-aryamontri, Andrew Winter, Livia Perfetto, Leonardo Briganti, Luana Licata, Marta Iannuccelli, Luisa Castagnoli, Gianni Cesareni, Mike Tyers, Gerold Schneider, Fabio Rinaldi, Robert Leaman, Graciela Gonzalez, Sergio Matos, Sun Kim, W Wilbur, Luis Rocha, Hagit Shatkay, Ashish V Tendulkar, Shashank Agarwal, Feifan Liu, Xinglong Wang, Rafal Rak, Keith Noto, Charles Elkan, Zhiyong Lu et al. BMC Bioinformatics 2011, 12(Suppl 8):S3 (3 October 2011)

Abstract | Full text | PDF | PubMed

44.

Research   Open Access Highly Accessed

Osteoblastic differentiation and stress response of human mesenchymal stem cells exposed to alternating current electric fields

Marie Hronik-Tupaj, William L Rice, Mark Cronin-Golomb, David L Kaplan, Irene Georgakoudi BioMedical Engineering OnLine 2011, 10:9 (26 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

Review   Open Access Highly Accessed

Focal brain inflammation and autism

Theoharis C Theoharides, Shahrzad Asadi, Arti B Patel Journal of Neuroinflammation 2013, 10:46 (9 April 2013)

Abstract | Full text | PDF | PubMed

46.

Research   Open Access Highly Accessed

Mercury induces inflammatory mediator release from human mast cells

Duraisamy Kempuraj, Shahrzad Asadi, Bodi Zhang, Akrivi Manola, Jennifer Hogan, Erika Peterson, Theoharis C Theoharides Journal of Neuroinflammation 2010, 7:20 (11 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

Research   Open Access Highly Accessed

Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients

Marjolein de Wit, Chris Gennings, Wendy I Jenvey, Scott K Epstein Critical Care 2008, 12:R70 (20 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Medicine | F1000 Biology

48.

Method   Open Access Highly Accessed

FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data

Andrea Sboner, Lukas Habegger, Dorothee Pflueger, Stephane Terry, David Z Chen, Joel S Rozowsky, Ashutosh K Tewari, Naoki Kitabayashi, Benjamin J Moss, Mark S Chee, Francesca Demichelis, Mark A Rubin, Mark B Gerstein Genome Biology 2010, 11:R104 (21 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

FusionSeq is a method for identifying fusion transcripts from RNA-seq data. Novel fusions are identified in prostate cancer datasets.

49.

Review   Open Access

Novel strategies in tendon and ligament tissue engineering: Advanced biomaterials and regeneration motifs

Catherine K Kuo, Joseph E Marturano, Rocky S Tuan Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology 2010, 2:20 (20 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

Research article   Open Access Highly Accessed

Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil

Antonio Camargo, Juan Ruano, Juan M Fernandez, Laurence D Parnell, Anabel Jimenez, Monica Santos-Gonzalez, Carmen Marin, Pablo Perez-Martinez, Marino Uceda, Jose Lopez-Miranda, Francisco Perez-Jimenez BMC Genomics 2010, 11:253 (20 April 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Eating a breakfast containing olive oil rich in phenolic compounds reduced the expression of pro-inflammatory genes associated with cardiovascular disease and diabetes in patients with metabolic syndrome, compared to those eating breakfasts with low-phenolic olive oil.

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