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16 December 2009
 
We are delighted to announce that the Chinese Academy of Sciences (CAS) is now a BioMed Central Member. This Membership means that CAS researchers will receive a heavily subsidized discount on the article-processing charge for all articles published by its researchers in any of our 205 open access journals. By making the decision to become a BioMed Central Member, CAS has shown significant support to open access publishing.

Getting into a rhythm - What are the most effective atrial fibrillation treatment methods?
BMC Medicine   Atrial fibrillation (AF) is the most common type of cardiac arrhythmia affecting about 1% of the general population. Treatments such as rate controlling therapy and anticoagulants are commonly used to stabilise heart AF. But, how
effective are the current range of treatments for AF and does the time of intervention impact on the eventual outcome of this prevalent condition? In BMC Medicine this week, Paulus Kirchhof discusses the range of treatments available to AF sufferers and the reasons why these treatments do not improve outcomes.
 
Unique metabolic roles of PPARdelta
Unique metabolic roles of PPARdelta   The distinct catabolic role of peroxisome proliferator-activated receptor delta is reported in new research published in Genome Medicine, with therapeutic implications for type 2 diabetes, dyslipidemia, and metabolic syndrome.

New supplements
 
BMC Bioinformatics and BMC Genomics   BMC Bioinformatics and BMC Genomics have published the Proceedings of the Eight International Conference on Bioinformatics (InCoB2009): Bioinformatics and the Proceedings of the Eighth International Conference on Bioinformatics (InCoB2009): Computational Biology. Singapore. 7-11 September 2009.
     
Scoliosis   Scoliosis has published the abstracts from the 6th International Conference on Conservative Management of Spinal Deformities. Lyon, France. 21-23 May 2009.
     
BMC Proceedings   BMC Proceedings has published the proceedings of the Genetic Analysis Workshop 16. St Louis, MO, USA. 17-20 September 2008.
 
 New from Journal of Biology
 
Major evolutionary change depends on changes in gene expression. Itay Tirosh and colleagues review recent research on the influence of promoter architecture and mutations in regulatory proteins on divergent expression patterns and suggest what is required for evolvability.

Promoter architecture and the evolvability of gene expression   Opinion
Promoter architecture and the evolvability of gene expression
Itay Tirosh, Naama Barkai and Kevin J Verstrepen
Journal of Biology 2009, 8:95

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Evolution, ecology and the engineered organism: lessons for synthetic biology
Jeffrey M Skerker, Julius B Lucks and Adam P Arkin
Genome Biology 2009, 10:114 (30 November 2009)

 

 
Sperm fertility independent of extraction site

  Sperm fertility independent of extraction site
Reproductive Biology and Endocrinology
2009, 7:142
ICSI live birth rates are similar in sperm extracted from the epididymis compared to the testes and are also similar in obstructed versus non-obstructed types of azoospermia.
 
Men slowed down by insulin resistance?   Men slowed down by insulin resistance?
BMC Geriatrics 2009, 9:49
Insulin resistance is associated with a lower walking speed in older non-diabetic men, but not women, making it a potential target for reducing functional decline with age in men.

 
 


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Proteomic analysis of blastema formation in regenerating axolotl limbs
Proteomic analysis of blastema formation in regenerating axolotl limbs.


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