Systems Biology Gateway

Welcome to the BioMed Central Systems Biology gateway, highlighting recent articles and news in Systems Biology.


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  • Image attributed to: from Erdmann and colleagues

    Stem cell fingerprinting

    A robust method for cellular phenotyping in primary human mesenchymal stem cells using kinome fingerprinting to identify gene networks that characterize distinct primary cell populations.

    Genome Medicine 2015, 7:46
  • SDG8 in plants

    Histone methyltransferase SDG8 regulates methylation marks associated with light and carbon responses in Arabidopsis

    Genome Biology 2015, 16:79
  • Image attributed to: From Fig 4, Vikes? et al, BMC Cancer 15:151

    Molecular features of CUPs

    Cancers of unknown primary origin (CUP) exhibit distinct molecular features compared to metastases of known origin and display signatures of chromosome instability which may account for their uncommon clinical presentation and poor outcome.

    BMC Cancer 2015, 15:151
  • Transcriptome population genetics

    An RNA-seq study of human placenta reveals variation in transcription between individuals and between human groups

    Genome Biology 2015, 16:54
  • Solving the myseries of congenital imprinting disorders

    The new consortium aims to promote better clinical care and scientific investigation of imprinting disorders, a group of eight rare but probably underdiagnosed congenital diseases affecting growth, development and metabolism.

    Clinical Epigenetics 2015, 7:23

News and events

Da_Vinci_Vitruvian_man_clip Cell Communication and Signaling has published a review series on 'Systems Biology and Medicine'

The collection, edited by Fred Schaper and Stephan Feller, provides a comprehensive overview of current models and known networks in signal transduction, including reviews on apoptosis, dopamine metabolism and probabilistic Boolean networks. BioMed Central's magazine Biome published a feature about the series.

Beyond the Genome 2013